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The map label for this gene is mtrC [H]

Identifier: 186475413

GI number: 186475413

Start: 729678

End: 730955

Strand: Direct

Name: mtrC [H]

Synonym: Bphy_0647

Alternate gene names: 186475413

Gene position: 729678-730955 (Clockwise)

Preceding gene: 186475412

Following gene: 186475414

Centisome position: 20.97

GC content: 68.47

Gene sequence:

>1278_bases
ATGGGATGGACATTTCGACACCCGTCGATACTTGCCGCTTGGCCGCTGGCATCACGCTTTGCGCTCGCGGCGGCATTGGT
GTCCGCCTTGTCCCTGACCGCCTGTAAAAAAGCGCCCACCGAACCCCCGCGCCCGACTGTCGAAGTGACGGTGGTCACGG
TTGCGCAGAAGGAAACGCCCGTCGACTTCGAGTTCACCGCGCAGACGCAGAGTTCGCGCGAAGTCGAAATCCGCGCGCGC
GTCGACGGCTTTCTCGAGCGGCGTCTGTACGACGAAGGCGCGCTGGTCAAGGAAGGCCAGGTGCTGTTCGTGATAGACCG
CAAGCCCTTCGAAGCCGCGCTGCAATCGGCCAGGGGCGTGCTCGCGCAGCAGCAGGCGCGCCTGCTCGTCACCAGACAGA
ACCTCGCGCGCGTCGTGCCGCTCGCCGCGCAGAACGCGCTGAGCAAGAAGGACCTGGACGACGCCACCGGCAACGAGAAG
GAAGCCGAAGCCGCCGTGATCGCCGCGCAGGGCGAGGTGCGCACGGCCGAACTGAACCTGAGCTACTGCACGATCCGCTC
GCCGCTCAAGGGGCTGTCGAGCTTCGCGCGCGTGCAGGACGGCAGCTACGTCACGCCGACGCAATCGGGCCTGCTGACGT
ACGTCTACCAGCTCGATCCGATGTGGGTGAACTTCAGCATCTCCGAGAACGAACTGCTGCGCTACCGCGAGCAGATCGCC
AAGGGCCTGCTGCGCTTTCCCGCCGACAACCGGTTCGACGTGACCGTGATCCAGGCCGACGGCTCGGTCTATCCGCAAAA
AGGCCGTATCGATTTCACGAACCCCGCGTTCAGCCAGCAGACGGGCACCTTCCTCGTGCGCGCGACCTTCGCCAATCCGG
ACGGCACGCTGCGCCCGGGCCAGTTCGTGCGCGCGAAAGTGTCGGGCGCGGTGCGCCCCAACGCGATCCTCGTGCCGCAG
CGCGCGGTGCTGCAGGGCGCGAAGAGCCACTTCGTGTGGGTGCTCGACCAGGACGCGAAGCCGCATCAGCGTGTGGTCGA
TGTCGGCGACTGGCACGGCGACGACTGGTTCGTCAACGAAGGCCTGAAGCCGGGCGAGCGCGTGGTGGTCGACGGCGCGA
TCCGCGTGTCGTCGGATGCGCAGATCAAGGTGGTGAGCGCGCCGCCGGGCTCGGGCGCGCCCGGCACGCCCGCGGCCCCT
GCGTCGGCGCCCGCGGCGGCGGCGTCCGTGCCCGTGGCGACCGTAGCCGGGACGCAGGCGCGTCCGGCCAGCCCCTGA

Upstream 100 bases:

>100_bases
TTGCATCGGACTCGCCAGGTTGGCTGGCGTGCCTACTGTTGGTCTGCCGGGCAACGCAAGCGCGGGCGGACGCAATCGTT
TCGAGTTGGGGAGATTTGTC

Downstream 100 bases:

>100_bases
GCCGATGTGAAGCCCCGATGACCCGACGCCATCCGGCCCCCCCGATCCGATGAACATCTCCCACTTCTGCATCGACCGCC
CGATCTTCGCCTCGGTCATC

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MGWTFRHPSILAAWPLASRFALAAALVSALSLTACKKAPTEPPRPTVEVTVVTVAQKETPVDFEFTAQTQSSREVEIRAR
VDGFLERRLYDEGALVKEGQVLFVIDRKPFEAALQSARGVLAQQQARLLVTRQNLARVVPLAAQNALSKKDLDDATGNEK
EAEAAVIAAQGEVRTAELNLSYCTIRSPLKGLSSFARVQDGSYVTPTQSGLLTYVYQLDPMWVNFSISENELLRYREQIA
KGLLRFPADNRFDVTVIQADGSVYPQKGRIDFTNPAFSQQTGTFLVRATFANPDGTLRPGQFVRAKVSGAVRPNAILVPQ
RAVLQGAKSHFVWVLDQDAKPHQRVVDVGDWHGDDWFVNEGLKPGERVVVDGAIRVSSDAQIKVVSAPPGSGAPGTPAAP
ASAPAAAASVPVATVAGTQARPASP

Sequences:

>Translated_425_residues
MGWTFRHPSILAAWPLASRFALAAALVSALSLTACKKAPTEPPRPTVEVTVVTVAQKETPVDFEFTAQTQSSREVEIRAR
VDGFLERRLYDEGALVKEGQVLFVIDRKPFEAALQSARGVLAQQQARLLVTRQNLARVVPLAAQNALSKKDLDDATGNEK
EAEAAVIAAQGEVRTAELNLSYCTIRSPLKGLSSFARVQDGSYVTPTQSGLLTYVYQLDPMWVNFSISENELLRYREQIA
KGLLRFPADNRFDVTVIQADGSVYPQKGRIDFTNPAFSQQTGTFLVRATFANPDGTLRPGQFVRAKVSGAVRPNAILVPQ
RAVLQGAKSHFVWVLDQDAKPHQRVVDVGDWHGDDWFVNEGLKPGERVVVDGAIRVSSDAQIKVVSAPPGSGAPGTPAAP
ASAPAAAASVPVATVAGTQARPASP
>Mature_424_residues
GWTFRHPSILAAWPLASRFALAAALVSALSLTACKKAPTEPPRPTVEVTVVTVAQKETPVDFEFTAQTQSSREVEIRARV
DGFLERRLYDEGALVKEGQVLFVIDRKPFEAALQSARGVLAQQQARLLVTRQNLARVVPLAAQNALSKKDLDDATGNEKE
AEAAVIAAQGEVRTAELNLSYCTIRSPLKGLSSFARVQDGSYVTPTQSGLLTYVYQLDPMWVNFSISENELLRYREQIAK
GLLRFPADNRFDVTVIQADGSVYPQKGRIDFTNPAFSQQTGTFLVRATFANPDGTLRPGQFVRAKVSGAVRPNAILVPQR
AVLQGAKSHFVWVLDQDAKPHQRVVDVGDWHGDDWFVNEGLKPGERVVVDGAIRVSSDAQIKVVSAPPGSGAPGTPAAPA
SAPAAAASVPVATVAGTQARPASP

Specific function: Cell membrane lipoprotein, involved in cell membrane permeability to hydrophobic compounds such as antibiotics, dyes and detergents [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786668, Length=366, Percent_Identity=34.9726775956284, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1789665, Length=379, Percent_Identity=32.1899736147757, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1789929, Length=371, Percent_Identity=33.4231805929919, Blast_Score=188, Evalue=5e-49,
Organism=Escherichia coli, GI87082036, Length=314, Percent_Identity=31.5286624203822, Blast_Score=143, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 45786; Mature: 45655

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGWTFRHPSILAAWPLASRFALAAALVSALSLTACKKAPTEPPRPTVEVTVVTVAQKETP
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCC
VDFEFTAQTQSSREVEIRARVDGFLERRLYDEGALVKEGQVLFVIDRKPFEAALQSARGV
CCEEEEECCCCCCEEEEEEHHHHHHHHHHHCCCCEEECCCEEEEECCCCHHHHHHHHHHH
LAQQQARLLVTRQNLARVVPLAAQNALSKKDLDDATGNEKEAEAAVIAAQGEVRTAELNL
HHHHHHHHEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEEE
SYCTIRSPLKGLSSFARVQDGSYVTPTQSGLLTYVYQLDPMWVNFSISENELLRYREQIA
EEEEHHHHHHHHHHHHHHCCCCEECCCCCCEEEEEEEECCEEEEEEECHHHHHHHHHHHH
KGLLRFPADNRFDVTVIQADGSVYPQKGRIDFTNPAFSQQTGTFLVRATFANPDGTLRPG
HHHHHCCCCCCEEEEEEEECCCCCCCCCEEECCCCCCCCCCCEEEEEEEEECCCCCCCCC
QFVRAKVSGAVRPNAILVPQRAVLQGAKSHFVWVLDQDAKPHQRVVDVGDWHGDDWFVNE
CEEEEEECCCCCCCEEECCCHHHHCCCCCEEEEEECCCCCCCHHEEECCCCCCCCEEECC
GLKPGERVVVDGAIRVSSDAQIKVVSAPPGSGAPGTPAAPASAPAAAASVPVATVAGTQA
CCCCCCEEEEECEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHCCCEEEECCCCC
RPASP
CCCCC
>Mature Secondary Structure 
GWTFRHPSILAAWPLASRFALAAALVSALSLTACKKAPTEPPRPTVEVTVVTVAQKETP
CCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCC
VDFEFTAQTQSSREVEIRARVDGFLERRLYDEGALVKEGQVLFVIDRKPFEAALQSARGV
CCEEEEECCCCCCEEEEEEHHHHHHHHHHHCCCCEEECCCEEEEECCCCHHHHHHHHHHH
LAQQQARLLVTRQNLARVVPLAAQNALSKKDLDDATGNEKEAEAAVIAAQGEVRTAELNL
HHHHHHHHEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEEE
SYCTIRSPLKGLSSFARVQDGSYVTPTQSGLLTYVYQLDPMWVNFSISENELLRYREQIA
EEEEHHHHHHHHHHHHHHCCCCEECCCCCCEEEEEEEECCEEEEEEECHHHHHHHHHHHH
KGLLRFPADNRFDVTVIQADGSVYPQKGRIDFTNPAFSQQTGTFLVRATFANPDGTLRPG
HHHHHCCCCCCEEEEEEEECCCCCCCCCEEECCCCCCCCCCCEEEEEEEEECCCCCCCCC
QFVRAKVSGAVRPNAILVPQRAVLQGAKSHFVWVLDQDAKPHQRVVDVGDWHGDDWFVNE
CEEEEEECCCCCCCEEECCCHHHHCCCCCEEEEEECCCCCCCHHEEECCCCCCCCEEECC
GLKPGERVVVDGAIRVSSDAQIKVVSAPPGSGAPGTPAAPASAPAAAASVPVATVAGTQA
CCCCCCEEEEECEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHCCCEEEECCCCC
RPASP
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8196548 [H]