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The map label for this gene is degP [H]

Identifier: 186475239

GI number: 186475239

Start: 534937

End: 536439

Strand: Direct

Name: degP [H]

Synonym: Bphy_0471

Alternate gene names: 186475239

Gene position: 534937-536439 (Clockwise)

Preceding gene: 186475238

Following gene: 186475240

Centisome position: 15.38

GC content: 64.6

Gene sequence:

>1503_bases
ATGAAAGCAAATATGCTGACCCGTAGCGCCGTCGCGGCGGCCGTCGTCATCGCTTTGTCGGCGGGTTATGTGGCCGGCCA
CCGCAATGTCCCGGCGCCCGCGGTGATCACCCCGGCCGTGGCCGCGATGATGCCCGCCGAAGCCGCGGCCAAAACGGGTA
TCCCCGATTTCTCGGGTCTCGTCGAAACTTATGGTCCCGCTGTCGTCAACATCAGCGCGAAGCACGTCGTCAAGCAGACG
GCGATGCGCGGCGGCAACAACAGCGGCCAGTTGCCCATCGACCCGAGCGATCCGTTTTATCAGTTCTACCGCCACTTTTT
TGGCCAGATGCCGGGTGGCCCCAATGGCGGCGGTGACGACGGCGGCGACCGTCCGAGCGCGAGCCTCGGCTCCGGCTTCA
TTATCAGCAGCGATGGTTATGTGCTGACCAATGCGCACGTCGTCGACGGTGCGAACGTCGTCACCGTGAAACTCACCGAC
AAGCGCGAGTACAGGGCGAAAGTGGTCGGCGCCGACAAGCAGTCGGATGTCGCAGTCCTGAAGATCGACGCGAAGGATCT
GCCGACCGTGAAGATCGGCGATCCGCGCCAGAGCAAGGTCGGCCAGTGGGTCGTCGCGATCGGCTCGCCCTACGGCTTCG
ACAACACGGTGACGTCGGGCATCATCAGCGCGAAGTCGCGCTCGCTGCCGGACGAGAACTACACGCCGTTCATCCAGACG
GACGTGCCCGTGAATCCGGGTAACTCGGGCGGCCCGCTGTTCAATCTGCAAGGCGAAGTGATCGGCATCAATTCGATGAT
CTATTCGCAGACGGGCGGCTTCCAGGGCCTTTCGTTCGCTATCCCGATCAATGAGGCGATCAAGGTCAAGGACGATCTCG
TAAAGACCGGCCACGTGAGCCGCGGCCGTCTCGGCGTCGCGGTGCAGAGTGTGAACCAGACGCTCGCGGATTCATTCGGC
ATGAAGAAGCCGCAAGGCGCGCTGGTCAGCTCCGTCGATCCGGGCGGCCCGGCGGCGAAAGCAGGCCTGCAGCCCGGCGA
CGTGATCCTGTCGGTGGATGGCGTCGACGTGGTGGATTCGGCGGCGCTGCCTTCGCAGATCGCGGGCATCAGGCCGGGCA
AGCAAGTCGACGTGCAGGTGTGGCGCGACAAGTCGACGAAAGATATGAAAGTGACGATCGGCTCGTTGTCCGACGTGAAA
GCGGCCGCGAACGACGACGGTGGTCCCGCGCAGATGCAAGGCCGCCTCGGCGTCGCCGTGCGTCCGCTGACGCCGCAGGA
GAAGAGCGGCGCGTCTGTGTCGCACGGTCTGTTGGTGCAGGACGCGAGCGGCGCGGCGGCGAGCGCGGGTATCCAGCCCG
GGGACGTGATTCTGGCCGTCAACGGACGCGCGGTGTCGAGCGTCGATCAGCTGAAGCAGGCGGTATCTGGAGCAGGTAAC
AGCATCGCGCTCCTGATCCAGCGCGACAACTCGCAGATCTTCGTGCCCGTCGATCTGGGCTGA

Upstream 100 bases:

>100_bases
CAAGGCTTTCATCGCGGCTGCGTTGTTTAAGACTGATTTAAGAGACGCCACGTACGCTTCGATTCATCGAAGAGTCAACT
CTCCCAATCAGGAGTACACG

Downstream 100 bases:

>100_bases
CATTGAACCCGGACTGACCTGGCGCGAGCAGCGGATGGCGTCGGCAGGCGCGGGACGGTAAAAGCTGCCGGTCATGGAAA
AAGTGGCGGTTCGCTGCGTG

Product: protease Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MKANMLTRSAVAAAVVIALSAGYVAGHRNVPAPAVITPAVAAMMPAEAAAKTGIPDFSGLVETYGPAVVNISAKHVVKQT
AMRGGNNSGQLPIDPSDPFYQFYRHFFGQMPGGPNGGGDDGGDRPSASLGSGFIISSDGYVLTNAHVVDGANVVTVKLTD
KREYRAKVVGADKQSDVAVLKIDAKDLPTVKIGDPRQSKVGQWVVAIGSPYGFDNTVTSGIISAKSRSLPDENYTPFIQT
DVPVNPGNSGGPLFNLQGEVIGINSMIYSQTGGFQGLSFAIPINEAIKVKDDLVKTGHVSRGRLGVAVQSVNQTLADSFG
MKKPQGALVSSVDPGGPAAKAGLQPGDVILSVDGVDVVDSAALPSQIAGIRPGKQVDVQVWRDKSTKDMKVTIGSLSDVK
AAANDDGGPAQMQGRLGVAVRPLTPQEKSGASVSHGLLVQDASGAAASAGIQPGDVILAVNGRAVSSVDQLKQAVSGAGN
SIALLIQRDNSQIFVPVDLG

Sequences:

>Translated_500_residues
MKANMLTRSAVAAAVVIALSAGYVAGHRNVPAPAVITPAVAAMMPAEAAAKTGIPDFSGLVETYGPAVVNISAKHVVKQT
AMRGGNNSGQLPIDPSDPFYQFYRHFFGQMPGGPNGGGDDGGDRPSASLGSGFIISSDGYVLTNAHVVDGANVVTVKLTD
KREYRAKVVGADKQSDVAVLKIDAKDLPTVKIGDPRQSKVGQWVVAIGSPYGFDNTVTSGIISAKSRSLPDENYTPFIQT
DVPVNPGNSGGPLFNLQGEVIGINSMIYSQTGGFQGLSFAIPINEAIKVKDDLVKTGHVSRGRLGVAVQSVNQTLADSFG
MKKPQGALVSSVDPGGPAAKAGLQPGDVILSVDGVDVVDSAALPSQIAGIRPGKQVDVQVWRDKSTKDMKVTIGSLSDVK
AAANDDGGPAQMQGRLGVAVRPLTPQEKSGASVSHGLLVQDASGAAASAGIQPGDVILAVNGRAVSSVDQLKQAVSGAGN
SIALLIQRDNSQIFVPVDLG
>Mature_500_residues
MKANMLTRSAVAAAVVIALSAGYVAGHRNVPAPAVITPAVAAMMPAEAAAKTGIPDFSGLVETYGPAVVNISAKHVVKQT
AMRGGNNSGQLPIDPSDPFYQFYRHFFGQMPGGPNGGGDDGGDRPSASLGSGFIISSDGYVLTNAHVVDGANVVTVKLTD
KREYRAKVVGADKQSDVAVLKIDAKDLPTVKIGDPRQSKVGQWVVAIGSPYGFDNTVTSGIISAKSRSLPDENYTPFIQT
DVPVNPGNSGGPLFNLQGEVIGINSMIYSQTGGFQGLSFAIPINEAIKVKDDLVKTGHVSRGRLGVAVQSVNQTLADSFG
MKKPQGALVSSVDPGGPAAKAGLQPGDVILSVDGVDVVDSAALPSQIAGIRPGKQVDVQVWRDKSTKDMKVTIGSLSDVK
AAANDDGGPAQMQGRLGVAVRPLTPQEKSGASVSHGLLVQDASGAAASAGIQPGDVILAVNGRAVSSVDQLKQAVSGAGN
SIALLIQRDNSQIFVPVDLG

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI7019477, Length=281, Percent_Identity=37.0106761565836, Blast_Score=152, Evalue=9e-37,
Organism=Homo sapiens, GI4506141, Length=252, Percent_Identity=38.8888888888889, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI22129776, Length=258, Percent_Identity=37.5968992248062, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI24308541, Length=245, Percent_Identity=36.3265306122449, Blast_Score=135, Evalue=1e-31,
Organism=Escherichia coli, GI1789629, Length=509, Percent_Identity=34.3811394891945, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1786356, Length=382, Percent_Identity=39.2670157068063, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1789630, Length=271, Percent_Identity=40.9594095940959, Blast_Score=191, Evalue=8e-50,
Organism=Drosophila melanogaster, GI24646839, Length=296, Percent_Identity=36.1486486486487, Blast_Score=152, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 51273; Mature: 51273

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKANMLTRSAVAAAVVIALSAGYVAGHRNVPAPAVITPAVAAMMPAEAAAKTGIPDFSGL
CCCCHHHHHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCHHHH
VETYGPAVVNISAKHVVKQTAMRGGNNSGQLPIDPSDPFYQFYRHFFGQMPGGPNGGGDD
HHHCCCEEEEEHHHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHCCCCCCCCCCCC
GGDRPSASLGSGFIISSDGYVLTNAHVVDGANVVTVKLTDKREYRAKVVGADKQSDVAVL
CCCCCCCCCCCCEEEECCCEEEEEEEEECCCCEEEEEEECCCCEEEEEECCCCCCCEEEE
KIDAKDLPTVKIGDPRQSKVGQWVVAIGSPYGFDNTVTSGIISAKSRSLPDENYTPFIQT
EECCCCCCEEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEE
DVPVNPGNSGGPLFNLQGEVIGINSMIYSQTGGFQGLSFAIPINEAIKVKDDLVKTGHVS
CCCCCCCCCCCCEEEECCCEEEEEEEEEECCCCCCCEEEEECCCCCEEEHHHHHHCCCCC
RGRLGVAVQSVNQTLADSFGMKKPQGALVSSVDPGGPAAKAGLQPGDVILSVDGVDVVDS
CCEEEEEHHHHHHHHHHHCCCCCCCCCEEECCCCCCCHHHCCCCCCCEEEEECCCCHHCC
AALPSQIAGIRPGKQVDVQVWRDKSTKDMKVTIGSLSDVKAAANDDGGPAQMQGRLGVAV
CCCCHHHHCCCCCCEEEEEEECCCCCCEEEEEECCCCHHHHCCCCCCCCCEECCCCCEEE
RPLTPQEKSGASVSHGLLVQDASGAAASAGIQPGDVILAVNGRAVSSVDQLKQAVSGAGN
ECCCCCCCCCCCCCCCEEEECCCCCHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCC
SIALLIQRDNSQIFVPVDLG
EEEEEEEECCCEEEEEEECC
>Mature Secondary Structure
MKANMLTRSAVAAAVVIALSAGYVAGHRNVPAPAVITPAVAAMMPAEAAAKTGIPDFSGL
CCCCHHHHHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCHHHH
VETYGPAVVNISAKHVVKQTAMRGGNNSGQLPIDPSDPFYQFYRHFFGQMPGGPNGGGDD
HHHCCCEEEEEHHHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHCCCCCCCCCCCC
GGDRPSASLGSGFIISSDGYVLTNAHVVDGANVVTVKLTDKREYRAKVVGADKQSDVAVL
CCCCCCCCCCCCEEEECCCEEEEEEEEECCCCEEEEEEECCCCEEEEEECCCCCCCEEEE
KIDAKDLPTVKIGDPRQSKVGQWVVAIGSPYGFDNTVTSGIISAKSRSLPDENYTPFIQT
EECCCCCCEEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEE
DVPVNPGNSGGPLFNLQGEVIGINSMIYSQTGGFQGLSFAIPINEAIKVKDDLVKTGHVS
CCCCCCCCCCCCEEEECCCEEEEEEEEEECCCCCCCEEEEECCCCCEEEHHHHHHCCCCC
RGRLGVAVQSVNQTLADSFGMKKPQGALVSSVDPGGPAAKAGLQPGDVILSVDGVDVVDS
CCEEEEEHHHHHHHHHHHCCCCCCCCCEEECCCCCCCHHHCCCCCCCEEEEECCCCHHCC
AALPSQIAGIRPGKQVDVQVWRDKSTKDMKVTIGSLSDVKAAANDDGGPAQMQGRLGVAV
CCCCHHHHCCCCCCEEEEEEECCCCCCEEEEEECCCCHHHHCCCCCCCCCEECCCCCEEE
RPLTPQEKSGASVSHGLLVQDASGAAASAGIQPGDVILAVNGRAVSSVDQLKQAVSGAGN
ECCCCCCCCCCCCCCCEEEECCCCCHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCC
SIALLIQRDNSQIFVPVDLG
EEEEEEEECCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]