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The map label for this gene is qseC [H]

Identifier: 186475238

GI number: 186475238

Start: 533522

End: 534823

Strand: Direct

Name: qseC [H]

Synonym: Bphy_0470

Alternate gene names: 186475238

Gene position: 533522-534823 (Clockwise)

Preceding gene: 186475237

Following gene: 186475239

Centisome position: 15.33

GC content: 68.89

Gene sequence:

>1302_bases
ATGCGTTCGATTCGCCGTCAACTGCTTTTCTGGCTGCTCGCCATCGTGTTGCTCGGCGTCGGCATCGCGGGCTGGCTGAT
CTACCGCCAGGCGCTCGCCGAAGCCAACGAACTGTTCGATTACCAGTTGCAGGAAATCGCCGCCGCACTGCCCGCCGAGC
CGTTCTCGCAGGTGCTTAGCTCGCGCGACACGGGCGACGAAGGCATCGTGCTGCAGATCTGGAATCGCAACGGCGTTCTG
ATGTACTACTCGCATCCGCGCGCGCCGCTCGCGCCGCGCGCCGAACTCGGCTTCTCGACGGAGCGCACGGAGCGCGGCGA
CTGGCGCGTGTATGGCGCGATCGTCGGCGACAACGTCGTTCAGCTCGCGCAGCCGCTGTCGGTGCGCAACCGGCTCGCCG
CGAACGTCGCGCTGCGCACGCTATGGCCGCTGATCGTGCTGCTGCCGCTGCTGGGCGTGGCCGTGTGGGGCGTGGTCGGA
CGCGGGCTCGAGCCGCTGCGGCGCGTGACGGGTGCGCTCGACACGCGTCATCCCGAAGCGCTCGATCCGCTGCCCGACTC
GCGTCTGCCGCTCGAAGTACAGCCGCTCGTGCGGGCGTTGAACGGTCTGCTCGAACGCCTCTCGGTCGCGCTCGATACCC
AGAAGGCTTTTGTCGCCGACGCCGCGCACGAACTGCGCACGCCGCTTGCCGCCGTGCAGATCCAGTCGCAACTGGTGGCG
CGCGCGCAAGACGAAGCCGAGCGCAGCGAAGCGTTGCGCGATCTGCAGGCGGGCGTCACGCGCGCGACGCGTCTCGCCGA
ACAGCTGCTCGCGCTCGCGCGTTCCGAACCGGACGGACACGCGGCGACGGGCACAGTCGACCTCGACGCGCTCGTGCACG
ACTGCGTGACCGCGCATCTGCCGCTCGCGCAGAAGCGCGGCGTCGATCTCGGCATCGAGGCGAGCGAGCCCGCGACCGTT
GCAGGGGACATGGAAGCGCTGCGTGTGATGCTCAACAATCTGATCGACAACGCGACCAAGTACACGCCGGAAGGCGGGCG
TGTCGACGTGTGTCTGCGTGTCGACAATGGCAGACCCGTCGTCGAGATTGGCGACAGCGGCCCCGGCATTCCGCCTGACG
AACGCAGCCGCGTGTTCGATCGCTTCTACCGCGTCGGCGCGGGTGCGAACCGCGCGCGCACCGACGTGTCGGGCAGCGGT
CTCGGCCTCGCGATCGTGCGCCGCATCGCGCTCCAGCATCACGCGAGCGTCGCGCTCGACGACTCCGCATCGGGCGGTTT
GCTGGTCAGCGTGCGCTTCTGA

Upstream 100 bases:

>100_bases
GTCGAAGTCTATATTCACGCGCTTCGCAAGAAGCTTGGCGCGGAATTGATCCGCAACGTGCGCGGTCTCGGTTACATGAT
CGCGAAGGAAGCCTGACACG

Downstream 100 bases:

>100_bases
ATCCCCCATCCAGCAAGGCTTTCATCGCGGCTGCGTTGTTTAAGACTGATTTAAGAGACGCCACGTACGCTTCGATTCAT
CGAAGAGTCAACTCTCCCAA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MRSIRRQLLFWLLAIVLLGVGIAGWLIYRQALAEANELFDYQLQEIAAALPAEPFSQVLSSRDTGDEGIVLQIWNRNGVL
MYYSHPRAPLAPRAELGFSTERTERGDWRVYGAIVGDNVVQLAQPLSVRNRLAANVALRTLWPLIVLLPLLGVAVWGVVG
RGLEPLRRVTGALDTRHPEALDPLPDSRLPLEVQPLVRALNGLLERLSVALDTQKAFVADAAHELRTPLAAVQIQSQLVA
RAQDEAERSEALRDLQAGVTRATRLAEQLLALARSEPDGHAATGTVDLDALVHDCVTAHLPLAQKRGVDLGIEASEPATV
AGDMEALRVMLNNLIDNATKYTPEGGRVDVCLRVDNGRPVVEIGDSGPGIPPDERSRVFDRFYRVGAGANRARTDVSGSG
LGLAIVRRIALQHHASVALDDSASGGLLVSVRF

Sequences:

>Translated_433_residues
MRSIRRQLLFWLLAIVLLGVGIAGWLIYRQALAEANELFDYQLQEIAAALPAEPFSQVLSSRDTGDEGIVLQIWNRNGVL
MYYSHPRAPLAPRAELGFSTERTERGDWRVYGAIVGDNVVQLAQPLSVRNRLAANVALRTLWPLIVLLPLLGVAVWGVVG
RGLEPLRRVTGALDTRHPEALDPLPDSRLPLEVQPLVRALNGLLERLSVALDTQKAFVADAAHELRTPLAAVQIQSQLVA
RAQDEAERSEALRDLQAGVTRATRLAEQLLALARSEPDGHAATGTVDLDALVHDCVTAHLPLAQKRGVDLGIEASEPATV
AGDMEALRVMLNNLIDNATKYTPEGGRVDVCLRVDNGRPVVEIGDSGPGIPPDERSRVFDRFYRVGAGANRARTDVSGSG
LGLAIVRRIALQHHASVALDDSASGGLLVSVRF
>Mature_433_residues
MRSIRRQLLFWLLAIVLLGVGIAGWLIYRQALAEANELFDYQLQEIAAALPAEPFSQVLSSRDTGDEGIVLQIWNRNGVL
MYYSHPRAPLAPRAELGFSTERTERGDWRVYGAIVGDNVVQLAQPLSVRNRLAANVALRTLWPLIVLLPLLGVAVWGVVG
RGLEPLRRVTGALDTRHPEALDPLPDSRLPLEVQPLVRALNGLLERLSVALDTQKAFVADAAHELRTPLAAVQIQSQLVA
RAQDEAERSEALRDLQAGVTRATRLAEQLLALARSEPDGHAATGTVDLDALVHDCVTAHLPLAQKRGVDLGIEASEPATV
AGDMEALRVMLNNLIDNATKYTPEGGRVDVCLRVDNGRPVVEIGDSGPGIPPDERSRVFDRFYRVGAGANRARTDVSGSG
LGLAIVRRIALQHHASVALDDSASGGLLVSVRF

Specific function: Member of a two-component regulatory system qseB/qseC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=457, Percent_Identity=29.3216630196937, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1786783, Length=295, Percent_Identity=32.5423728813559, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1790551, Length=291, Percent_Identity=31.9587628865979, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788393, Length=243, Percent_Identity=31.6872427983539, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788279, Length=300, Percent_Identity=27, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786600, Length=221, Percent_Identity=31.6742081447964, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790346, Length=230, Percent_Identity=28.2608695652174, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790861, Length=301, Percent_Identity=28.9036544850498, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1787374, Length=290, Percent_Identity=27.2413793103448, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87082128, Length=226, Percent_Identity=30.5309734513274, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789808, Length=241, Percent_Identity=27.8008298755187, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1787894, Length=241, Percent_Identity=30.7053941908714, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI48994928, Length=201, Percent_Identity=29.3532338308458, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI145693157, Length=226, Percent_Identity=26.9911504424779, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788713, Length=248, Percent_Identity=25.4032258064516, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1786912, Length=224, Percent_Identity=27.2321428571429, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788549, Length=213, Percent_Identity=26.2910798122066, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789149, Length=205, Percent_Identity=26.8292682926829, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790436, Length=210, Percent_Identity=25.2380952380952, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 46900; Mature: 46900

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSIRRQLLFWLLAIVLLGVGIAGWLIYRQALAEANELFDYQLQEIAAALPAEPFSQVLS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
SRDTGDEGIVLQIWNRNGVLMYYSHPRAPLAPRAELGFSTERTERGDWRVYGAIVGDNVV
CCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCHHCCCCCCCCCCCCEEEEEEECCCHHH
QLAQPLSVRNRLAANVALRTLWPLIVLLPLLGVAVWGVVGRGLEPLRRVTGALDTRHPEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCC
LDPLPDSRLPLEVQPLVRALNGLLERLSVALDTQKAFVADAAHELRTPLAAVQIQSQLVA
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
RAQDEAERSEALRDLQAGVTRATRLAEQLLALARSEPDGHAATGTVDLDALVHDCVTAHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCC
PLAQKRGVDLGIEASEPATVAGDMEALRVMLNNLIDNATKYTPEGGRVDVCLRVDNGRPV
CCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCE
VEIGDSGPGIPPDERSRVFDRFYRVGAGANRARTDVSGSGLGLAIVRRIALQHHASVALD
EEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEC
DSASGGLLVSVRF
CCCCCCEEEEEEC
>Mature Secondary Structure
MRSIRRQLLFWLLAIVLLGVGIAGWLIYRQALAEANELFDYQLQEIAAALPAEPFSQVLS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
SRDTGDEGIVLQIWNRNGVLMYYSHPRAPLAPRAELGFSTERTERGDWRVYGAIVGDNVV
CCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCHHCCCCCCCCCCCCEEEEEEECCCHHH
QLAQPLSVRNRLAANVALRTLWPLIVLLPLLGVAVWGVVGRGLEPLRRVTGALDTRHPEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCC
LDPLPDSRLPLEVQPLVRALNGLLERLSVALDTQKAFVADAAHELRTPLAAVQIQSQLVA
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
RAQDEAERSEALRDLQAGVTRATRLAEQLLALARSEPDGHAATGTVDLDALVHDCVTAHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCC
PLAQKRGVDLGIEASEPATVAGDMEALRVMLNNLIDNATKYTPEGGRVDVCLRVDNGRPV
CCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCE
VEIGDSGPGIPPDERSRVFDRFYRVGAGANRARTDVSGSGLGLAIVRRIALQHHASVALD
EEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEC
DSASGGLLVSVRF
CCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]