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The map label for this gene is ribB [H]

Identifier: 186475186

GI number: 186475186

Start: 476228

End: 476962

Strand: Direct

Name: ribB [H]

Synonym: Bphy_0417

Alternate gene names: 186475186

Gene position: 476228-476962 (Clockwise)

Preceding gene: 186475185

Following gene: 186475190

Centisome position: 13.69

GC content: 64.35

Gene sequence:

>735_bases
ATGTCCGTTGTCTCCCACTCTGCTGCATTTGCCTGGCCTGCACCTTCCGTCGTCGCGGAGGATGCCGTCGCCGATCTCCC
GTTGCTTGCCACCGAACCCGTTCCGCCGCGCGTCGCTGCCGCGCTCCACGCTTTGCGCGCAGGCCGTGCCGTCGTGCTTC
AGGACGATCACGACCGCGAGAACGAAGCCGATCTGATCATGTCCGCGGAGCGTATGAGCGTCGAGATGATGGCGCTGTTC
ATTCGCGAGTGCAGCGGCATCGTGTGTTTGTGCCTGACCGACGAGAAGGTACGCGCGCTCGAGTTGCCGCCGATGACGGC
TCACAACGAGAGCCGCAACACGACGGCGTTTACTGTATCGATAGAGGCACGCGAGGGCGTATCGACTGGGGTATCGGCCG
CGGACCGACTGACGACGATTCGTGCCGCTATCGCGGACGACGCGAAGCCTGCCGATATCGTGCGGCCTGGCCACGTATAT
CCGTTGCGTGCGATGCCAGGCGGCGTGCTCGCGCGTCGCGGGCATACGGAAGGGACCGTCGATCTCGTGACGTTGGCGGG
GCTGAAGCCCGCCGGTGTGTTGTGCGAACTGATGAACGCCGATGGCACGATGATGCGGGGTGCTGATGTCGAGGCGTTTG
CCGCCAGGCATGACATGCCGATGCTGACCATTGCCGAGCTTGTCGAGTTTCGGCGCTCGCTGGCGCTTGCCCGAGAGGCG
TGTGTCGAGGTCTGA

Upstream 100 bases:

>100_bases
CGTTCGTCGCATGGCAGCCGTTTCGGCTGGCGGGGCGCGTTTGTCTGTTTGCAATGCCCTGAAACGTTTTTCGCCCACAC
TCTTGCGAGGAGCGTTTCAT

Downstream 100 bases:

>100_bases
GGTTGTTGTCTGCGACGCGGCCTGCCGGTTTGGGTCTTGATTTCGGCTGTTGGCGAAAAGCGGGCGCTGCCGCGCGGCAG
TCAAAAACTGGCGCTGCGTC

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MSVVSHSAAFAWPAPSVVAEDAVADLPLLATEPVPPRVAAALHALRAGRAVVLQDDHDRENEADLIMSAERMSVEMMALF
IRECSGIVCLCLTDEKVRALELPPMTAHNESRNTTAFTVSIEAREGVSTGVSAADRLTTIRAAIADDAKPADIVRPGHVY
PLRAMPGGVLARRGHTEGTVDLVTLAGLKPAGVLCELMNADGTMMRGADVEAFAARHDMPMLTIAELVEFRRSLALAREA
CVEV

Sequences:

>Translated_244_residues
MSVVSHSAAFAWPAPSVVAEDAVADLPLLATEPVPPRVAAALHALRAGRAVVLQDDHDRENEADLIMSAERMSVEMMALF
IRECSGIVCLCLTDEKVRALELPPMTAHNESRNTTAFTVSIEAREGVSTGVSAADRLTTIRAAIADDAKPADIVRPGHVY
PLRAMPGGVLARRGHTEGTVDLVTLAGLKPAGVLCELMNADGTMMRGADVEAFAARHDMPMLTIAELVEFRRSLALAREA
CVEV
>Mature_243_residues
SVVSHSAAFAWPAPSVVAEDAVADLPLLATEPVPPRVAAALHALRAGRAVVLQDDHDRENEADLIMSAERMSVEMMALFI
RECSGIVCLCLTDEKVRALELPPMTAHNESRNTTAFTVSIEAREGVSTGVSAADRLTTIRAAIADDAKPADIVRPGHVYP
LRAMPGGVLARRGHTEGTVDLVTLAGLKPAGVLCELMNADGTMMRGADVEAFAARHDMPMLTIAELVEFRRSLALAREAC
VEV

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=207, Percent_Identity=60.3864734299517, Blast_Score=248, Evalue=3e-67,
Organism=Saccharomyces cerevisiae, GI6320695, Length=204, Percent_Identity=40.6862745098039, Blast_Score=168, Evalue=7e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422 [H]

Pfam domain/function: PF00926 DHBP_synthase [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 26001; Mature: 25870

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVVSHSAAFAWPAPSVVAEDAVADLPLLATEPVPPRVAAALHALRAGRAVVLQDDHDRE
CCCCCCCCEECCCCCHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHCCCEEEEECCCCCC
NEADLIMSAERMSVEMMALFIRECSGIVCLCLTDEKVRALELPPMTAHNESRNTTAFTVS
CCHHHEEHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCCCCCCCEEEEEE
IEAREGVSTGVSAADRLTTIRAAIADDAKPADIVRPGHVYPLRAMPGGVLARRGHTEGTV
EECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCEEECCCCCCCE
DLVTLAGLKPAGVLCELMNADGTMMRGADVEAFAARHDMPMLTIAELVEFRRSLALAREA
EEEEECCCCCHHHHHHHHCCCCCEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
CVEV
HHCC
>Mature Secondary Structure 
SVVSHSAAFAWPAPSVVAEDAVADLPLLATEPVPPRVAAALHALRAGRAVVLQDDHDRE
CCCCCCCEECCCCCHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHCCCEEEEECCCCCC
NEADLIMSAERMSVEMMALFIRECSGIVCLCLTDEKVRALELPPMTAHNESRNTTAFTVS
CCHHHEEHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCCCCCCCEEEEEE
IEAREGVSTGVSAADRLTTIRAAIADDAKPADIVRPGHVYPLRAMPGGVLARRGHTEGTV
EECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCEEECCCCCCCE
DLVTLAGLKPAGVLCELMNADGTMMRGADVEAFAARHDMPMLTIAELVEFRRSLALAREA
EEEEECCCCCHHHHHHHHCCCCCEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
CVEV
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA