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The map label for this gene is hexR [H]

Identifier: 186475134

GI number: 186475134

Start: 413349

End: 414242

Strand: Direct

Name: hexR [H]

Synonym: Bphy_0365

Alternate gene names: 186475134

Gene position: 413349-414242 (Clockwise)

Preceding gene: 186475132

Following gene: 186475135

Centisome position: 11.88

GC content: 66.33

Gene sequence:

>894_bases
ATGAATTCCTCTGCCGAACCCGTTGCCTTCGACATCGTCGCCCGCATTGCAGAATGCGCACCCGGGTTGCGCTCGGCCGA
GCGCAAGGTCGCGGCGCTGATTCTCGACGACCTGACGGGCGCGTCGCGCGCTAGCATCGGCGCACTGGCCGAAAGAGCCG
AAGTGAGCGTCGCGACGGTCACGCGGTTCGCGAAGGCCGTCGGTTGCCGCGACGTGCGCGAGCTGAAGTTGCGGCTCGCG
CAGGCGGCGGCCGTCGGCCAGCGCTTCCTGCAGACTAGCGCGCAAAACGATGACACGCCCGAGCCATTGGCGACGCGGGT
CTTCGACGAGTTGCAGACGGCGCTCACGCACAATCATCAGTTGCTGTGTCAGGCACCCGTTGAGCAGGCGGCAGCCGCGC
TGCGCGAAGCGCGCATGATTTACGTGTTCGGCATGGGCGGCGGCTCGACCGCGCTCGCCGACGAAATGCGCTTCCGCCTC
GTCCGTCTGGGCCGGCCTGTTGCGACTTACCAGGACGCGTTGTTGCAGCGCATGGTCGCGTCAACGGTCTCGCGCGACAC
GGTGGTGATTGCGTTGTCGACGACGGGCCGCGTGCCGGAAATGGTGGACAGCTGCAAGATCGCGCGCAGTTACGGCGCGA
CGCTGATCACGGTGACGGCGCCCGCATCGCCGCTCGCGAAGCTGGCCGACTGGGTGATTCCCATCGTCGCGTTTGAAACC
GACTTCATTTACAAGCCGTCGTCGTCGCGCTACGCGATGATGATGGCGCTCGACGTGCTGGTCACCGAACTCGCGTTGAG
TCTCGGTGACGAGAGCCGCGAACTGCTGCGCCGCATGAAGCATGCGCTCGACGCGCATCGCGGCGGCGGCGACCGACAAC
CGCTAGGAGACTGA

Upstream 100 bases:

>100_bases
ACTTTCGTATGTTACCGAAAGTACGATGGTTGATGAAATGTTATTTAGTACCACGCGTGCCGCGACCGATGTTAGCGGCC
GCGCGAGGCACATGCGCGCC

Downstream 100 bases:

>100_bases
TCCATGCATTCGCACCCTGAAGCCGCCGATACGCTGATCGTCGGCGCGCAGTTGTACGATGGCACGGGCGCGCCGCCCGT
CGAACGCGACGTCGCGTTGC

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: Hex regulon repressor [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MNSSAEPVAFDIVARIAECAPGLRSAERKVAALILDDLTGASRASIGALAERAEVSVATVTRFAKAVGCRDVRELKLRLA
QAAAVGQRFLQTSAQNDDTPEPLATRVFDELQTALTHNHQLLCQAPVEQAAAALREARMIYVFGMGGGSTALADEMRFRL
VRLGRPVATYQDALLQRMVASTVSRDTVVIALSTTGRVPEMVDSCKIARSYGATLITVTAPASPLAKLADWVIPIVAFET
DFIYKPSSSRYAMMMALDVLVTELALSLGDESRELLRRMKHALDAHRGGGDRQPLGD

Sequences:

>Translated_297_residues
MNSSAEPVAFDIVARIAECAPGLRSAERKVAALILDDLTGASRASIGALAERAEVSVATVTRFAKAVGCRDVRELKLRLA
QAAAVGQRFLQTSAQNDDTPEPLATRVFDELQTALTHNHQLLCQAPVEQAAAALREARMIYVFGMGGGSTALADEMRFRL
VRLGRPVATYQDALLQRMVASTVSRDTVVIALSTTGRVPEMVDSCKIARSYGATLITVTAPASPLAKLADWVIPIVAFET
DFIYKPSSSRYAMMMALDVLVTELALSLGDESRELLRRMKHALDAHRGGGDRQPLGD
>Mature_297_residues
MNSSAEPVAFDIVARIAECAPGLRSAERKVAALILDDLTGASRASIGALAERAEVSVATVTRFAKAVGCRDVRELKLRLA
QAAAVGQRFLQTSAQNDDTPEPLATRVFDELQTALTHNHQLLCQAPVEQAAAALREARMIYVFGMGGGSTALADEMRFRL
VRLGRPVATYQDALLQRMVASTVSRDTVVIALSTTGRVPEMVDSCKIARSYGATLITVTAPASPLAKLADWVIPIVAFET
DFIYKPSSSRYAMMMALDVLVTELALSLGDESRELLRRMKHALDAHRGGGDRQPLGD

Specific function: Represses the expression of the hex regulon (zwf, eda, glp and gap) [H]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=286, Percent_Identity=32.8671328671329, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1788767, Length=283, Percent_Identity=26.1484098939929, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87082369, Length=245, Percent_Identity=24.8979591836735, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 31983; Mature: 31983

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSSAEPVAFDIVARIAECAPGLRSAERKVAALILDDLTGASRASIGALAERAEVSVATV
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
TRFAKAVGCRDVRELKLRLAQAAAVGQRFLQTSAQNDDTPEPLATRVFDELQTALTHNHQ
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCC
LLCQAPVEQAAAALREARMIYVFGMGGGSTALADEMRFRLVRLGRPVATYQDALLQRMVA
EEEECCHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
STVSRDTVVIALSTTGRVPEMVDSCKIARSYGATLITVTAPASPLAKLADWVIPIVAFET
HHHCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCC
DFIYKPSSSRYAMMMALDVLVTELALSLGDESRELLRRMKHALDAHRGGGDRQPLGD
CEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNSSAEPVAFDIVARIAECAPGLRSAERKVAALILDDLTGASRASIGALAERAEVSVATV
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
TRFAKAVGCRDVRELKLRLAQAAAVGQRFLQTSAQNDDTPEPLATRVFDELQTALTHNHQ
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCC
LLCQAPVEQAAAALREARMIYVFGMGGGSTALADEMRFRLVRLGRPVATYQDALLQRMVA
EEEECCHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
STVSRDTVVIALSTTGRVPEMVDSCKIARSYGATLITVTAPASPLAKLADWVIPIVAFET
HHHCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCC
DFIYKPSSSRYAMMMALDVLVTELALSLGDESRELLRRMKHALDAHRGGGDRQPLGD
CEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]