| Definition | Burkholderia phymatum STM815 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010622 |
| Length | 3,479,187 |
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The map label for this gene is kefB [H]
Identifier: 186475101
GI number: 186475101
Start: 372982
End: 374985
Strand: Direct
Name: kefB [H]
Synonym: Bphy_0332
Alternate gene names: 186475101
Gene position: 372982-374985 (Clockwise)
Preceding gene: 186475089
Following gene: 186475102
Centisome position: 10.72
GC content: 65.32
Gene sequence:
>2004_bases ATGATTTCGCCGCTCGAAATGACGCTGTTTCTGCTGCTGGCCTCAGTGGTGGGCGTCGTCGTGTTCCGCTACCTGAACCT GCCGCCGATGCTCGGCTATCTGTCCGTGGGGATCGTGGTCGGACCGCACGCGTTCGGCATCGTGCCCGACTCGGTCGGCG CGCAGAACCTCGCGGAATTCGGCGTGGTGTTCCTGATGTTCTCGATCGGGCTGGAGTTTTCGCTCGCGAAGCTGCGCTCG ATGCGCCGGCTCGTGTTCGGACTGGGCTTGCTGCAGGTGCTCGGCACGATCGCCATCGCGGTGTCGCTCGGTTTCGTGTT CGAGCGCTGGGTGCACATCTCATGGCAGGCAAGCGTCGCACTGGGCGGCGCGCTGGCGATGTCGTCGACGGCCATCGTCA GCAAGATGCTCGCGGAGCGGCTCGAAATCGAAACCGAACACGGCCGCAATATCTTCGGCGTGCTGCTGTTCCAGGATCTG GCCGTGGTGCCGCTGCTGATCGTCATTGCGGCGCTCGGCGGGAGTTCGGACGATCTCGTCAGATCGCTCGGGATCGCGTC GATCAAGATCGTGATCGCATTGGCGCTGCTGCTGATCGTCGGGCAGAAGTTCATGACGCGCTGGTTCAACGTCGTCGCGC GGCGCCGTTCGCAGGAGCTGTTCGTCCTGAACCTGCTGCTTGTCACGCTGGGCGCCGCGTTCATCACGGATAAATTCGGC CTGTCGCTCGCGCTGGGCGCGTTCATCGCGGGCATGCTGATCGCCGAAACGCCGTACCGGCATCAGGTCGAAGAGGACAT CAAGCCGTTCCGTGACGTGCTGCTCGGGCTCTTCTTCGTGACGACGGGCATGCTGCTCAATCCGCGCGTGATCTGGGAGC ATCCGCTGATCGTGCTCGCGTTCCTGATCGGCCCCGTGCTCCTTAAAGCGGTGATGATCACGGGTCTCGCACGTCTGTTC GGTGCCACGCCGGGTGTCGCGATGCGTACGGGTATCGGGCTTGCGCAGGCGGGCGAGTTCGGCTTTGTGCTGCTCAACCT GATTCTCGATAAGCACCTGGTCGACGCAACGCTCTTGCAGGCCATTCTCGCCGCGATGCTGCTGTCGATGCTTGCCGCGC CGTTCATGATCCAGAACGCGGACCGCATCGTGCTGCGGCTGTCGTCGACTGAATGGATGATGCAGTCGTTGCAGATGACG CGCATCGCGACGCAAAGCCTCAAACAGAGCGGCCACGTGATCATCTGCGGCTATGGCCGCGCCGGGCAGAATCTCGCACG CATGCTGGAGCACGAGGGGCTGTCGTATGTCGCGCTCGACCTCGATCCCGACCGTGTGGCGGCCGCGGCGGCGGCGGGCG AGTCGGTCGTGTTCGGCGATGCCGGGCGGCGCGAGTCGCTGCTCGCAGCCGGTATCCACCGGGCGGCGACCGTGGCGATC ACGTATGCGAACACGCCGTCGGCGCTGCGCGTGCTGCATAACATTCACGAGCTCGAGCCGACGCTGCCTGTGATCGTGCG CACTGTCGACGATAGCGACCTCGAAAAGCTCCTCGCCGCGGGCGCGACGGAAGTGATTCCGGAGATCGTCGAGGGCAGCC TGATGCTCGCCTCGCACACGCTCGTCGTGATGGGCGTGCCCATGCGCCGGGTCGTGCGGCGAGTGGAGGAACTGCGCGAC GAGCGCTATAGTCTGCTGCGCGGCTACTTCCACGGCGCCGACGACGTGGATGACGACGACGGTCACGAGCAGGTGCGGCT ACAATCCGTGCCCGTCGACGAAAAGGCCGATGCCGTCGGGCGAACGCTCGAGGAACTCGGGCTGTTCGATCTCGGCGTCG AGGTGACGGCGATTCGCCGGCATGGCATTCGCGGCGTGGAGCCCGATCCATCGACCAAGCTGCGCGCGAGCGACATCGTC GTGCTGCGGGGTCTGCCCGAAGCGCTGGCGGAAGCGGAAGAGCGTCTGTCGAAGCATCGGCGCGCGGGGGCGGCGGCGGC CTGA
Upstream 100 bases:
>100_bases TCCGGACATTGCCTTCACAGGCCTCTCAACCTTGCTGCGCGGGCGTTTGCATGCAGCTTCGCCGACGAACCAGGACGCTC ACCCGGATGCGCTTTTGCCG
Downstream 100 bases:
>100_bases CGTTTGCTGTCGTTCTTCATCGCAGATCACGCGACGCGCTGTTCCCCACGTTTGTCGGACGCGCGCTGCACTCAGGCAAC TCACTGGAATTATCAGGGTC
Product: sodium/hydrogen exchanger
Products: Proton [Cytoplasm]; K (I) [Periplasm] [C]
Alternate protein names: K(+)/H(+) antiporter; NEM-activatable K(+)/H(+) antiporter [H]
Number of amino acids: Translated: 667; Mature: 667
Protein sequence:
>667_residues MISPLEMTLFLLLASVVGVVVFRYLNLPPMLGYLSVGIVVGPHAFGIVPDSVGAQNLAEFGVVFLMFSIGLEFSLAKLRS MRRLVFGLGLLQVLGTIAIAVSLGFVFERWVHISWQASVALGGALAMSSTAIVSKMLAERLEIETEHGRNIFGVLLFQDL AVVPLLIVIAALGGSSDDLVRSLGIASIKIVIALALLLIVGQKFMTRWFNVVARRRSQELFVLNLLLVTLGAAFITDKFG LSLALGAFIAGMLIAETPYRHQVEEDIKPFRDVLLGLFFVTTGMLLNPRVIWEHPLIVLAFLIGPVLLKAVMITGLARLF GATPGVAMRTGIGLAQAGEFGFVLLNLILDKHLVDATLLQAILAAMLLSMLAAPFMIQNADRIVLRLSSTEWMMQSLQMT RIATQSLKQSGHVIICGYGRAGQNLARMLEHEGLSYVALDLDPDRVAAAAAAGESVVFGDAGRRESLLAAGIHRAATVAI TYANTPSALRVLHNIHELEPTLPVIVRTVDDSDLEKLLAAGATEVIPEIVEGSLMLASHTLVVMGVPMRRVVRRVEELRD ERYSLLRGYFHGADDVDDDDGHEQVRLQSVPVDEKADAVGRTLEELGLFDLGVEVTAIRRHGIRGVEPDPSTKLRASDIV VLRGLPEALAEAEERLSKHRRAGAAAA
Sequences:
>Translated_667_residues MISPLEMTLFLLLASVVGVVVFRYLNLPPMLGYLSVGIVVGPHAFGIVPDSVGAQNLAEFGVVFLMFSIGLEFSLAKLRS MRRLVFGLGLLQVLGTIAIAVSLGFVFERWVHISWQASVALGGALAMSSTAIVSKMLAERLEIETEHGRNIFGVLLFQDL AVVPLLIVIAALGGSSDDLVRSLGIASIKIVIALALLLIVGQKFMTRWFNVVARRRSQELFVLNLLLVTLGAAFITDKFG LSLALGAFIAGMLIAETPYRHQVEEDIKPFRDVLLGLFFVTTGMLLNPRVIWEHPLIVLAFLIGPVLLKAVMITGLARLF GATPGVAMRTGIGLAQAGEFGFVLLNLILDKHLVDATLLQAILAAMLLSMLAAPFMIQNADRIVLRLSSTEWMMQSLQMT RIATQSLKQSGHVIICGYGRAGQNLARMLEHEGLSYVALDLDPDRVAAAAAAGESVVFGDAGRRESLLAAGIHRAATVAI TYANTPSALRVLHNIHELEPTLPVIVRTVDDSDLEKLLAAGATEVIPEIVEGSLMLASHTLVVMGVPMRRVVRRVEELRD ERYSLLRGYFHGADDVDDDDGHEQVRLQSVPVDEKADAVGRTLEELGLFDLGVEVTAIRRHGIRGVEPDPSTKLRASDIV VLRGLPEALAEAEERLSKHRRAGAAAA >Mature_667_residues MISPLEMTLFLLLASVVGVVVFRYLNLPPMLGYLSVGIVVGPHAFGIVPDSVGAQNLAEFGVVFLMFSIGLEFSLAKLRS MRRLVFGLGLLQVLGTIAIAVSLGFVFERWVHISWQASVALGGALAMSSTAIVSKMLAERLEIETEHGRNIFGVLLFQDL AVVPLLIVIAALGGSSDDLVRSLGIASIKIVIALALLLIVGQKFMTRWFNVVARRRSQELFVLNLLLVTLGAAFITDKFG LSLALGAFIAGMLIAETPYRHQVEEDIKPFRDVLLGLFFVTTGMLLNPRVIWEHPLIVLAFLIGPVLLKAVMITGLARLF GATPGVAMRTGIGLAQAGEFGFVLLNLILDKHLVDATLLQAILAAMLLSMLAAPFMIQNADRIVLRLSSTEWMMQSLQMT RIATQSLKQSGHVIICGYGRAGQNLARMLEHEGLSYVALDLDPDRVAAAAAAGESVVFGDAGRRESLLAAGIHRAATVAI TYANTPSALRVLHNIHELEPTLPVIVRTVDDSDLEKLLAAGATEVIPEIVEGSLMLASHTLVVMGVPMRRVVRRVEELRD ERYSLLRGYFHGADDVDDDDGHEQVRLQSVPVDEKADAVGRTLEELGLFDLGVEVTAIRRHGIRGVEPDPSTKLRASDIV VLRGLPEALAEAEERLSKHRRAGAAAA
Specific function: Transport system that facilitates potassium-efflux, possibly by potassium-proton antiport [H]
COG id: COG0475
COG function: function code P; Kef-type K+ transport systems, membrane components
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 RCK N-terminal domain [H]
Homologues:
Organism=Homo sapiens, GI157388921, Length=343, Percent_Identity=27.6967930029155, Blast_Score=100, Evalue=4e-21, Organism=Escherichia coli, GI1789749, Length=562, Percent_Identity=33.4519572953737, Blast_Score=253, Evalue=4e-68, Organism=Escherichia coli, GI1786232, Length=536, Percent_Identity=32.4626865671642, Blast_Score=243, Evalue=4e-65, Organism=Escherichia coli, GI1786685, Length=534, Percent_Identity=29.2134831460674, Blast_Score=194, Evalue=2e-50,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR006153 - InterPro: IPR020884 - InterPro: IPR004771 - InterPro: IPR016040 - InterPro: IPR003148 [H]
Pfam domain/function: PF00999 Na_H_Exchanger; PF02254 TrkA_N [H]
EC number: NA
Molecular weight: Translated: 72152; Mature: 72152
Theoretical pI: Translated: 6.42; Mature: 6.42
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.1 %Cys (Translated Protein) 3.3 %Met (Translated Protein) 3.4 %Cys+Met (Translated Protein) 0.1 %Cys (Mature Protein) 3.3 %Met (Mature Protein) 3.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MISPLEMTLFLLLASVVGVVVFRYLNLPPMLGYLSVGIVVGPHAFGIVPDSVGAQNLAEF CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHH GVVFLMFSIGLEFSLAKLRSMRRLVFGLGLLQVLGTIAIAVSLGFVFERWVHISWQASVA HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHH LGGALAMSSTAIVSKMLAERLEIETEHGRNIFGVLLFQDLAVVPLLIVIAALGGSSDDLV HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH RSLGIASIKIVIALALLLIVGQKFMTRWFNVVARRRSQELFVLNLLLVTLGAAFITDKFG HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH LSLALGAFIAGMLIAETPYRHQVEEDIKPFRDVLLGLFFVTTGMLLNPRVIWEHPLIVLA HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHCCCEEEHHHHHHHHH FLIGPVLLKAVMITGLARLFGATPGVAMRTGIGLAQAGEFGFVLLNLILDKHLVDATLLQ HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHH AILAAMLLSMLAAPFMIQNADRIVLRLSSTEWMMQSLQMTRIATQSLKQSGHVIICGYGR HHHHHHHHHHHHCCHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC AGQNLARMLEHEGLSYVALDLDPDRVAAAAAAGESVVFGDAGRRESLLAAGIHRAATVAI CCHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHEEEEE TYANTPSALRVLHNIHELEPTLPVIVRTVDDSDLEKLLAAGATEVIPEIVEGSLMLASHT EECCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCHHHHHHHHHCCCCEEEECC LVVMGVPMRRVVRRVEELRDERYSLLRGYFHGADDVDDDDGHEQVRLQSVPVDEKADAVG CEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCHHHHHH RTLEELGLFDLGVEVTAIRRHGIRGVEPDPSTKLRASDIVVLRGLPEALAEAEERLSKHR HHHHHCCHHHCCCHHHHHHHCCCCCCCCCCCCCEECCCEEEECCCHHHHHHHHHHHHHHH RAGAAAA HCCCCCC >Mature Secondary Structure MISPLEMTLFLLLASVVGVVVFRYLNLPPMLGYLSVGIVVGPHAFGIVPDSVGAQNLAEF CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHH GVVFLMFSIGLEFSLAKLRSMRRLVFGLGLLQVLGTIAIAVSLGFVFERWVHISWQASVA HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHH LGGALAMSSTAIVSKMLAERLEIETEHGRNIFGVLLFQDLAVVPLLIVIAALGGSSDDLV HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH RSLGIASIKIVIALALLLIVGQKFMTRWFNVVARRRSQELFVLNLLLVTLGAAFITDKFG HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH LSLALGAFIAGMLIAETPYRHQVEEDIKPFRDVLLGLFFVTTGMLLNPRVIWEHPLIVLA HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHCCCEEEHHHHHHHHH FLIGPVLLKAVMITGLARLFGATPGVAMRTGIGLAQAGEFGFVLLNLILDKHLVDATLLQ HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHH AILAAMLLSMLAAPFMIQNADRIVLRLSSTEWMMQSLQMTRIATQSLKQSGHVIICGYGR HHHHHHHHHHHHCCHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC AGQNLARMLEHEGLSYVALDLDPDRVAAAAAAGESVVFGDAGRRESLLAAGIHRAATVAI CCHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHEEEEE TYANTPSALRVLHNIHELEPTLPVIVRTVDDSDLEKLLAAGATEVIPEIVEGSLMLASHT EECCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCHHHHHHHHHCCCCEEEECC LVVMGVPMRRVVRRVEELRDERYSLLRGYFHGADDVDDDDGHEQVRLQSVPVDEKADAVG CEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCHHHHHH RTLEELGLFDLGVEVTAIRRHGIRGVEPDPSTKLRASDIVVLRGLPEALAEAEERLSKHR HHHHHCCHHHCCCHHHHHHHCCCCCCCCCCCCCEECCCEEEECCCHHHHHHHHHHHHHHH RAGAAAA HCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Proton [Periplasm]; K (I) [Cytoplasm] [C]
Specific reaction: Proton [Periplasm] + K (I) [Cytoplasm] = Proton [Cytoplasm] + K (I) [Periplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA