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The map label for this gene is glmS [H]

Identifier: 186475063

GI number: 186475063

Start: 334589

End: 335596

Strand: Direct

Name: glmS [H]

Synonym: Bphy_0294

Alternate gene names: 186475063

Gene position: 334589-335596 (Clockwise)

Preceding gene: 186475062

Following gene: 186475064

Centisome position: 9.62

GC content: 66.87

Gene sequence:

>1008_bases
ATGCTTAAAGAGGCGCTAGCGTCCGCTGACGTGGTCGCCGCGCAACTCAACGATACGTCGCGTGTGGAAGCGCTCGCGGC
CCGCCTTGCGCTGGAGCCGCGGCATGTCGCGCTGACCGTGGCGCGCGGCAGTTCGGATCACGCGGCGAGTTACTTCGCAT
CGCTGACGATGAGCCGCGTGGGCCTGCCCGTCGCGTCGCTGCCAATGTCCGTCGCCACGCTTCAGCAGGCGCCGCTGAAA
GTGAGCAACCAGCTTGCGCTTGGCTTCTCGCAATCCGGCAAGAGCCCGGATCTGGTCGGCACGATGCAGGCGCTGCGCGA
AGCCGGCGCGCTGACCGTGGCTGCCGTCAACGTGCCTGGCTCGCCGCTCGAACAGGCATGCGAGTTCTATCTGCCCCTCG
TCGCCGGTCCCGAACTGAGCGTCGCGGCAACCAAGAGCTATATCGCGATGCTGTCCGTGTCCGCGCAACTGGTCGCGCAC
TGGCAGAAGGACGATGCGCTGCTCGGCGCGCTGAAATCGCTGCCCGATGCACTCGCGCGTGCAGGCGCGCTCGACTGGTC
GAAGGCCGTGGACGAACTGCGCGACGTCGAACGCATGATCGTGATCGGCCGTGGGCTCGGGCTTGCGATCGCACAGGAAG
CGGCATTGAAACTCAAGGAAACGTCGGGCATCCAGGCCGAGGCGTTTTCGAGCGCGGAAGTGCGTCACGGCCCGATGGAA
CTGATCGACCGCGACTATCCGCTGCTGGTGTTCGCACCCCGCGGGCCGGAGCAGTCGGGCCTGTTGCAGCTGGCCCGCGA
CATGCAGGCGCGCGGCGCTCGCGTGCTGCTCGCGGCACCGGGCGACGTTCCCGAAGCCACCTTGCCGCTCGTATCGACGG
CGCACGCGGCGCTCGATCCGATTGCCGCGATCCTTTCTTTCTATGTGATGGCAGCCGGCCTCGCCGCCGCTCGCGGACGA
AATCCCGATGCGCCGCGCCATCTGATGAAAGTCACCGAAACTCACTGA

Upstream 100 bases:

>100_bases
CGTGGCCGCCTCGCGCGCGGCGCGTGGGCCGATGTCGTGGTGTTCGACCGCGAACTGGCGCTGACGGCGACTTACGTCGA
AGGAGAATCGATTGTCGAAT

Downstream 100 bases:

>100_bases
TCGAGATATTCAGATGCGACGTGTCGAGGAGTCCCGTTTGAAGAGCCATTCCGAAGGCCATATTGTCCTGCTCGCGCCGA
TGACGGGTCCCGTCGTGCCG

Product: glutamine--fructose-6-phosphate transaminase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MLKEALASADVVAAQLNDTSRVEALAARLALEPRHVALTVARGSSDHAASYFASLTMSRVGLPVASLPMSVATLQQAPLK
VSNQLALGFSQSGKSPDLVGTMQALREAGALTVAAVNVPGSPLEQACEFYLPLVAGPELSVAATKSYIAMLSVSAQLVAH
WQKDDALLGALKSLPDALARAGALDWSKAVDELRDVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
LIDRDYPLLVFAPRGPEQSGLLQLARDMQARGARVLLAAPGDVPEATLPLVSTAHAALDPIAAILSFYVMAAGLAAARGR
NPDAPRHLMKVTETH

Sequences:

>Translated_335_residues
MLKEALASADVVAAQLNDTSRVEALAARLALEPRHVALTVARGSSDHAASYFASLTMSRVGLPVASLPMSVATLQQAPLK
VSNQLALGFSQSGKSPDLVGTMQALREAGALTVAAVNVPGSPLEQACEFYLPLVAGPELSVAATKSYIAMLSVSAQLVAH
WQKDDALLGALKSLPDALARAGALDWSKAVDELRDVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
LIDRDYPLLVFAPRGPEQSGLLQLARDMQARGARVLLAAPGDVPEATLPLVSTAHAALDPIAAILSFYVMAAGLAAARGR
NPDAPRHLMKVTETH
>Mature_335_residues
MLKEALASADVVAAQLNDTSRVEALAARLALEPRHVALTVARGSSDHAASYFASLTMSRVGLPVASLPMSVATLQQAPLK
VSNQLALGFSQSGKSPDLVGTMQALREAGALTVAAVNVPGSPLEQACEFYLPLVAGPELSVAATKSYIAMLSVSAQLVAH
WQKDDALLGALKSLPDALARAGALDWSKAVDELRDVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
LIDRDYPLLVFAPRGPEQSGLLQLARDMQARGARVLLAAPGDVPEATLPLVSTAHAALDPIAAILSFYVMAAGLAAARGR
NPDAPRHLMKVTETH

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI205277386, Length=303, Percent_Identity=26.7326732673267, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI4826742, Length=310, Percent_Identity=26.7741935483871, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1790167, Length=266, Percent_Identity=31.203007518797, Blast_Score=114, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17539970, Length=309, Percent_Identity=26.537216828479, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17532897, Length=310, Percent_Identity=26.1290322580645, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17532899, Length=310, Percent_Identity=26.1290322580645, Blast_Score=101, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6322745, Length=309, Percent_Identity=26.2135922330097, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6323731, Length=183, Percent_Identity=24.5901639344262, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357745, Length=308, Percent_Identity=24.6753246753247, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 35039; Mature: 35039

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKEALASADVVAAQLNDTSRVEALAARLALEPRHVALTVARGSSDHAASYFASLTMSRV
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHH
GLPVASLPMSVATLQQAPLKVSNQLALGFSQSGKSPDLVGTMQALREAGALTVAAVNVPG
CCCHHHCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCC
SPLEQACEFYLPLVAGPELSVAATKSYIAMLSVSAQLVAHWQKDDALLGALKSLPDALAR
CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
AGALDWSKAVDELRDVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
HCCCCHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHCCCCHH
LIDRDYPLLVFAPRGPEQSGLLQLARDMQARGARVLLAAPGDVPEATLPLVSTAHAALDP
HHCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHH
IAAILSFYVMAAGLAAARGRNPDAPRHLMKVTETH
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MLKEALASADVVAAQLNDTSRVEALAARLALEPRHVALTVARGSSDHAASYFASLTMSRV
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHH
GLPVASLPMSVATLQQAPLKVSNQLALGFSQSGKSPDLVGTMQALREAGALTVAAVNVPG
CCCHHHCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCC
SPLEQACEFYLPLVAGPELSVAATKSYIAMLSVSAQLVAHWQKDDALLGALKSLPDALAR
CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
AGALDWSKAVDELRDVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
HCCCCHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHCCCCHH
LIDRDYPLLVFAPRGPEQSGLLQLARDMQARGARVLLAAPGDVPEATLPLVSTAHAALDP
HHCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHH
IAAILSFYVMAAGLAAARGRNPDAPRHLMKVTETH
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]