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The map label for this gene is ctaE [H]

Identifier: 186475050

GI number: 186475050

Start: 322264

End: 323121

Strand: Direct

Name: ctaE [H]

Synonym: Bphy_0281

Alternate gene names: 186475050

Gene position: 322264-323121 (Clockwise)

Preceding gene: 186475049

Following gene: 186475052

Centisome position: 9.26

GC content: 61.66

Gene sequence:

>858_bases
ATGAGCGGTCAAAACGAGAGCCCGTACTATTTCATACCGCATCCGTCGCGGCATCCGATCAGCGCGGCCGTTGGCCTGCT
GGTCATGCTCGGATCGTTTGCGGCGTGGGTGAACGGCGAGCCGTGGGCGCCCATCACGGCGCTGATCGGTCTGCTGTGGC
TGCTGTTCACGCTGTACCACTGGTTCGGCGATGCGATCTCCGAGTCGGAAGGCGGCATGTACGGCAAGCGTGTCGACACG
TCGTTCCGCTGGAGCATGAGCTGGTTCATCTTCTCCGAAGTCATGTTCTTCGGCGCGTTCTTCGGCGCGCTGTTCTACGC
GCGTGAGATCGCGATGCATCAGCTGGGCAGTCTTGACTACAAGCTGATCTGGCCGGATTTCACCGCGGTATGGCCGAATA
TCGGGCCGGCCGACCTTGTGTCGCACTTCAAGTCGATGACACCGTGGCCCGTACCCACCATCAACACCGCGCTGCTGCTG
TCGTCGGGCGCGACGTTGACGGTCTCGCATCACGCGCTGCGCGACAATCACCGCACGAAGGCAATCGCATGGCTCGCGGC
CACGCTGGTGCTGGGCGTGTCGTTCCTGTTCCTGCAAGGCTTCGAGTATTTCCACGCGTACAACGAACTGAACCTGACGC
TCGCATCGGGCGTGTACGGCTCGACGTTCTTCCTGCTGACGGGCTTCCATGGTTTTCACGTGTTCCTCGGCGGCACGATG
CTGGCGGTGGTGCTGGTGCGGCTGATCCGTGGCCACTTCACGGCTGATCATCACTTCGCCTTCGAGGGCGCGGCGTGGTA
CTGGCACTTTGTCGACGTCGTGTGGCTGGGTCTGTACGTCGTCGTGTATTGGCTGTAA

Upstream 100 bases:

>100_bases
GCAACGCAGCGCGCCGCAGGAGAGAGCCGGGGCGCAGCGCAGTCGGCTGCGGATTCAACCGGACCAAGCGGAACAACTGG
ACTGAAGTGGAGAAACAACA

Downstream 100 bases:

>100_bases
GCGTTGTTTGAAAGTTGCAAAGCGGCTGCGCGCCATGCGTCACATCGACGCAGTGCGGCCGCGAAGGCCGATCGGAAGAA
GTCGTAGACAGCGCCGCCCT

Product: cytochrome c oxidase subunit III

Products: NA

Alternate protein names: Cytochrome aa3 subunit 3; Cytochrome c oxidase polypeptide III; Oxidase aa(3) subunit 3 [H]

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MSGQNESPYYFIPHPSRHPISAAVGLLVMLGSFAAWVNGEPWAPITALIGLLWLLFTLYHWFGDAISESEGGMYGKRVDT
SFRWSMSWFIFSEVMFFGAFFGALFYAREIAMHQLGSLDYKLIWPDFTAVWPNIGPADLVSHFKSMTPWPVPTINTALLL
SSGATLTVSHHALRDNHRTKAIAWLAATLVLGVSFLFLQGFEYFHAYNELNLTLASGVYGSTFFLLTGFHGFHVFLGGTM
LAVVLVRLIRGHFTADHHFAFEGAAWYWHFVDVVWLGLYVVVYWL

Sequences:

>Translated_285_residues
MSGQNESPYYFIPHPSRHPISAAVGLLVMLGSFAAWVNGEPWAPITALIGLLWLLFTLYHWFGDAISESEGGMYGKRVDT
SFRWSMSWFIFSEVMFFGAFFGALFYAREIAMHQLGSLDYKLIWPDFTAVWPNIGPADLVSHFKSMTPWPVPTINTALLL
SSGATLTVSHHALRDNHRTKAIAWLAATLVLGVSFLFLQGFEYFHAYNELNLTLASGVYGSTFFLLTGFHGFHVFLGGTM
LAVVLVRLIRGHFTADHHFAFEGAAWYWHFVDVVWLGLYVVVYWL
>Mature_284_residues
SGQNESPYYFIPHPSRHPISAAVGLLVMLGSFAAWVNGEPWAPITALIGLLWLLFTLYHWFGDAISESEGGMYGKRVDTS
FRWSMSWFIFSEVMFFGAFFGALFYAREIAMHQLGSLDYKLIWPDFTAVWPNIGPADLVSHFKSMTPWPVPTINTALLLS
SGATLTVSHHALRDNHRTKAIAWLAATLVLGVSFLFLQGFEYFHAYNELNLTLASGVYGSTFFLLTGFHGFHVFLGGTML
AVVLVRLIRGHFTADHHFAFEGAAWYWHFVDVVWLGLYVVVYWL

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=281, Percent_Identity=39.5017793594306, Blast_Score=163, Evalue=2e-40,
Organism=Escherichia coli, GI1786633, Length=142, Percent_Identity=32.3943661971831, Blast_Score=71, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6226542, Length=227, Percent_Identity=36.5638766519824, Blast_Score=118, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 32174; Mature: 32043

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGQNESPYYFIPHPSRHPISAAVGLLVMLGSFAAWVNGEPWAPITALIGLLWLLFTLYH
CCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
WFGDAISESEGGMYGKRVDTSFRWSMSWFIFSEVMFFGAFFGALFYAREIAMHQLGSLDY
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
KLIWPDFTAVWPNIGPADLVSHFKSMTPWPVPTINTALLLSSGATLTVSHHALRDNHRTK
EEECCCHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHEEECCCEEEEEHHHHHCCCHHH
AIAWLAATLVLGVSFLFLQGFEYFHAYNELNLTLASGVYGSTFFLLTGFHGFHVFLGGTM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHCHHHHHHHHHHHH
LAVVLVRLIRGHFTADHHFAFEGAAWYWHFVDVVWLGLYVVVYWL
HHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SGQNESPYYFIPHPSRHPISAAVGLLVMLGSFAAWVNGEPWAPITALIGLLWLLFTLYH
CCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
WFGDAISESEGGMYGKRVDTSFRWSMSWFIFSEVMFFGAFFGALFYAREIAMHQLGSLDY
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
KLIWPDFTAVWPNIGPADLVSHFKSMTPWPVPTINTALLLSSGATLTVSHHALRDNHRTK
EEECCCHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHEEECCCEEEEEHHHHHCCCHHH
AIAWLAATLVLGVSFLFLQGFEYFHAYNELNLTLASGVYGSTFFLLTGFHGFHVFLGGTM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHCHHHHHHHHHHHH
LAVVLVRLIRGHFTADHHFAFEGAAWYWHFVDVVWLGLYVVVYWL
HHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3019767; 2832167; 7651515 [H]