Click here to switch to the map view.

The map label for this gene is ctaD [H]

Identifier: 186475046

GI number: 186475046

Start: 319348

End: 320961

Strand: Direct

Name: ctaD [H]

Synonym: Bphy_0277

Alternate gene names: 186475046

Gene position: 319348-320961 (Clockwise)

Preceding gene: 186475045

Following gene: 186475047

Centisome position: 9.18

GC content: 62.7

Gene sequence:

>1614_bases
ATGTCTAGCATCGGACACGATGTAGCCGCAGGGCACGAGCACGTGCACGGCGACCACGCCCACGAGACGCCGCATGGCTG
GCGCCGCTGGCTGTACGCGACGAACCACAAGGACATCGGTACGCTGTATCTGCTGTTTTCGTTCATCATGTTCCTGTCGG
GCGGCGTGATGGCGCTGGGCATCCGCGCCGAGCTGTTCGAGCCGGGCCTGCAGATCATGCGCCCAGAGTTCTTCAACCAG
CTGACCACCATGCATGGGCTGATCATGGTGTTCGGCGCGATCATGCCGGCCTTCGTCGGCTTCGCTAACTGGATGATTCC
GCTGCAGATCGGCGCATCCGACATGGCGTTCGCACGGATGAACAACTTCAGCTTCTGGCTGCTGCCCGTTGCTGCCGTGC
TGCTGGTCGGTTCGTTCTTCGTGCCGGGCGGCGCGACGGCCGCCGGCTGGACGCTGTACGCGCCGCTGTCAACGCAGATG
GGTCCGGGCATGGACTTCGCCATCTTCGCGGTGCACATCATGGGTGCGTCGTCGATCATGGGCGGCATCAACATCGTCGT
GACGATCCTGAACATGCGCGCGCCGGGCCTTACGCTGATGAAGATGCCGATGTTCGTGTGGACGTGGCTGATCACGGCCT
ACCTGCTAATCGCCGTAATGCCGGTGCTGGCAGGCGCGATCACGATGGTGCTGTTCGACCGTCACTTCGGCACGTCGTTC
TTCAGCGCGGCAGGCGGCGGCGACCCGGTGATGTACCAGCACATCTTCTGGTTCTTCGGCCATCCCGAGGTGTACATCAT
GATCTTGCCGGCGTTCGGGATCGTGTCTCAGGTGATCCCGGCGTTCGCGCGCAAGCCCCTGTTCGGCTATAGCTCGATGG
TGTACGCAACGGCGTCGATCGCGATCCTGTCGTTCATGGTCTGGGCGCACCACATGTTCGCTACGGGCATGCCCGTCACG
GGGCAGTTGTTCTTCATGTACGCGACGATGCTGATCGCCGTGCCGACGGGCGTGAAGGTGTTCAACTGGGTCGCGACGAT
GTGGCGCGGTTCACTGACGTTCGAAACGCCGATGCTGTTCGCGGTGGGCTTCCTGTTCGTGTTCACGTTCGGCGGTCTGA
CGGGGCTGATGCTCGCCATGGCGCCACTCGACATCCAGTATCACGGCACCTACTTCGTGGTCGCGCACTTCCACTACGTG
CTGGTGGCGGGTTCGCTGTTCGGCCTCTTTGCCGGGTGGTATTACTGGTCGCCAAAGTGGACGGGTTGGATGTACAACGA
GACGCGCGGCAAGATCCACTTCTGGTCGTCGCTGATCTTCTTCAACCTCGCGTTCCTGCCCATGCACTTCGTCGGTCTTG
CGGGCATGCCGCGTCGCTACGCCGACTATCCGGCGCAATTCGCCGACTGGAACCAGGTGATCACCATCGGCGCATTCGGC
TTCGGTCTCGCCCAGGTGTATTTCCTGTTCGCGGTCGCGCTGCCGGCTTATCGCGGCGGCGGCGAACTCGAAAAAGCGAG
CGACAAGCCGTGGGACGGCGCGACGGGCCTCGAGTGGACCGTGCCGAGCCCGGCTCCGTTCCACACGTTCGAAAACCCGC
CGACGGTCGAATAA

Upstream 100 bases:

>100_bases
GGGCGGTGCGGACGCGAAGGAAGCACGCCGTGTAGAGATCAGCCCAGCGGCCTGACGTGCCACAGTCAGACAAAAGCAGC
ATTCGATTTAGGAGATTGTC

Downstream 100 bases:

>100_bases
GCCGCAAGCAGTCTTCGATGCTTCCACTTCGGCGTCGCGACGCCGGAGTGGGAGAGGAAGCAAACAGTGCAGCAGTACCG
CATCAAGAAAGTCGAGCATG

Product: cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 537; Mature: 536

Protein sequence:

>537_residues
MSSIGHDVAAGHEHVHGDHAHETPHGWRRWLYATNHKDIGTLYLLFSFIMFLSGGVMALGIRAELFEPGLQIMRPEFFNQ
LTTMHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARMNNFSFWLLPVAAVLLVGSFFVPGGATAAGWTLYAPLSTQM
GPGMDFAIFAVHIMGASSIMGGINIVVTILNMRAPGLTLMKMPMFVWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSF
FSAAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFARKPLFGYSSMVYATASIAILSFMVWAHHMFATGMPVT
GQLFFMYATMLIAVPTGVKVFNWVATMWRGSLTFETPMLFAVGFLFVFTFGGLTGLMLAMAPLDIQYHGTYFVVAHFHYV
LVAGSLFGLFAGWYYWSPKWTGWMYNETRGKIHFWSSLIFFNLAFLPMHFVGLAGMPRRYADYPAQFADWNQVITIGAFG
FGLAQVYFLFAVALPAYRGGGELEKASDKPWDGATGLEWTVPSPAPFHTFENPPTVE

Sequences:

>Translated_537_residues
MSSIGHDVAAGHEHVHGDHAHETPHGWRRWLYATNHKDIGTLYLLFSFIMFLSGGVMALGIRAELFEPGLQIMRPEFFNQ
LTTMHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARMNNFSFWLLPVAAVLLVGSFFVPGGATAAGWTLYAPLSTQM
GPGMDFAIFAVHIMGASSIMGGINIVVTILNMRAPGLTLMKMPMFVWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSF
FSAAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFARKPLFGYSSMVYATASIAILSFMVWAHHMFATGMPVT
GQLFFMYATMLIAVPTGVKVFNWVATMWRGSLTFETPMLFAVGFLFVFTFGGLTGLMLAMAPLDIQYHGTYFVVAHFHYV
LVAGSLFGLFAGWYYWSPKWTGWMYNETRGKIHFWSSLIFFNLAFLPMHFVGLAGMPRRYADYPAQFADWNQVITIGAFG
FGLAQVYFLFAVALPAYRGGGELEKASDKPWDGATGLEWTVPSPAPFHTFENPPTVE
>Mature_536_residues
SSIGHDVAAGHEHVHGDHAHETPHGWRRWLYATNHKDIGTLYLLFSFIMFLSGGVMALGIRAELFEPGLQIMRPEFFNQL
TTMHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARMNNFSFWLLPVAAVLLVGSFFVPGGATAAGWTLYAPLSTQMG
PGMDFAIFAVHIMGASSIMGGINIVVTILNMRAPGLTLMKMPMFVWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSFF
SAAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFARKPLFGYSSMVYATASIAILSFMVWAHHMFATGMPVTG
QLFFMYATMLIAVPTGVKVFNWVATMWRGSLTFETPMLFAVGFLFVFTFGGLTGLMLAMAPLDIQYHGTYFVVAHFHYVL
VAGSLFGLFAGWYYWSPKWTGWMYNETRGKIHFWSSLIFFNLAFLPMHFVGLAGMPRRYADYPAQFADWNQVITIGAFGF
GLAQVYFLFAVALPAYRGGGELEKASDKPWDGATGLEWTVPSPAPFHTFENPPTVE

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=513, Percent_Identity=48.5380116959064, Blast_Score=448, Evalue=1e-126,
Organism=Escherichia coli, GI1786634, Length=518, Percent_Identity=40.5405405405405, Blast_Score=379, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6226519, Length=531, Percent_Identity=48.210922787194, Blast_Score=490, Evalue=1e-139,
Organism=Saccharomyces cerevisiae, GI6226524, Length=323, Percent_Identity=50.7739938080495, Blast_Score=333, Evalue=5e-92,
Organism=Saccharomyces cerevisiae, GI6226523, Length=247, Percent_Identity=47.7732793522267, Blast_Score=219, Evalue=7e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 59583; Mature: 59452

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.3 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIGHDVAAGHEHVHGDHAHETPHGWRRWLYATNHKDIGTLYLLFSFIMFLSGGVMALG
CCCCCCCHHCCCCCCCCCCCCCCCCHHHHHEEECCCCCHHHHHHHHHHHHHHCCCEEEEE
IRAELFEPGLQIMRPEFFNQLTTMHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARM
HHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHH
NNFSFWLLPVAAVLLVGSFFVPGGATAAGWTLYAPLSTQMGPGMDFAIFAVHIMGASSIM
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
GGINIVVTILNMRAPGLTLMKMPMFVWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSF
CCHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
FSAAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFARKPLFGYSSMVYATASI
HHCCCCCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
AILSFMVWAHHMFATGMPVTGQLFFMYATMLIAVPTGVKVFNWVATMWRGSLTFETPMLF
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHH
AVGFLFVFTFGGLTGLMLAMAPLDIQYHGTYFVVAHFHYVLVAGSLFGLFAGWYYWSPKW
HHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEHHHHHHHHHHHHHHHHHHHHEEECCCC
TGWMYNETRGKIHFWSSLIFFNLAFLPMHFVGLAGMPRRYADYPAQFADWNQVITIGAFG
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCEEEEEHHH
FGLAQVYFLFAVALPAYRGGGELEKASDKPWDGATGLEWTVPSPAPFHTFENPPTVE
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSIGHDVAAGHEHVHGDHAHETPHGWRRWLYATNHKDIGTLYLLFSFIMFLSGGVMALG
CCCCCCHHCCCCCCCCCCCCCCCCHHHHHEEECCCCCHHHHHHHHHHHHHHCCCEEEEE
IRAELFEPGLQIMRPEFFNQLTTMHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARM
HHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHH
NNFSFWLLPVAAVLLVGSFFVPGGATAAGWTLYAPLSTQMGPGMDFAIFAVHIMGASSIM
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
GGINIVVTILNMRAPGLTLMKMPMFVWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSF
CCHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
FSAAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFARKPLFGYSSMVYATASI
HHCCCCCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
AILSFMVWAHHMFATGMPVTGQLFFMYATMLIAVPTGVKVFNWVATMWRGSLTFETPMLF
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHH
AVGFLFVFTFGGLTGLMLAMAPLDIQYHGTYFVVAHFHYVLVAGSLFGLFAGWYYWSPKW
HHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEHHHHHHHHHHHHHHHHHHHHEEECCCC
TGWMYNETRGKIHFWSSLIFFNLAFLPMHFVGLAGMPRRYADYPAQFADWNQVITIGAFG
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCEEEEEHHH
FGLAQVYFLFAVALPAYRGGGELEKASDKPWDGATGLEWTVPSPAPFHTFENPPTVE
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2172930; 1965217; 12597275 [H]