Click here to switch to the map view.

The map label for this gene is ctaC [H]

Identifier: 186475045

GI number: 186475045

Start: 317629

End: 319302

Strand: Direct

Name: ctaC [H]

Synonym: Bphy_0276

Alternate gene names: 186475045

Gene position: 317629-319302 (Clockwise)

Preceding gene: 186475044

Following gene: 186475046

Centisome position: 9.13

GC content: 63.68

Gene sequence:

>1674_bases
ATGGAAATTTTGGGTAAGGAAGCTATGAAAACAATCAAGCGAGCCCTCACGGGTGTGCTGGCGTGTAGCGGACTGCTGTT
CGCCGGTGCCGCCCTTGCAGTCGGCGACAGTCCAGGCGGCCCCCGCGTCAACGAGATCAATCTCCAGCCGCCGGTGACGA
GGATTGCCGAAGAGCTCTACAGCCTCCATACGTTCATGCTGATTCTCTGCACGGTGATTTTCATCGGCGTGTTCGGCGTG
ATGTTCTATTCGATCTTCGCGCACCGCAAGTCGAAGGGCTACAAGGCGGCAAATTTCCACGAAAGCACCACCGTCGAAAT
CATCTGGACGGTCGTCCCGTTCATCATCGTCGTGCTGATGGCGCTGCCCGCCACGAAGACGGTCGTCGCGATGAAAGACA
CCACCAACGCCGACCTGACGGTCAAGGTCACCGGCTATCAGTGGAAGTGGGCCTATGACTACGTTAAGGGTCCGGGCGAA
GGCATCAACTTCTTTTCGACGCTGACCACGCCGCGCGCCGAAGTCGACGGCCGTCAGCCGATCACCGACACGTACCTGCA
GGAAGTCGACAACCCGCTCGTCGTGCCCGTGAACAAGAAGATCCGCATCATCACCACCGCCAACGACGTCGTGCACTCGT
GGTACGTGCCCGCGTTCGGCGTGAAGCAGGACGCTATTCCCGGCTTCGTGCGCGACACGTGGTTCAGGGCGGAGAAGGTA
GGCACCTATCGCGGCTTCTGTACCGAGCTGTGCGGCAAGGAACACGCGTTCATGCCCGTCGTCGTCAACGTGTTGTCGGA
TGAGGATTACGCGAAGTGGGTCGACGACCAGAAGAAGAAAATGGCCGCCGGTCAGGACGACCCGAACAAGAACTACACGC
TGGCCGAACTGATGGAGCGCGGCGGCAAGGTGTATTCGGCGAACTGCGCCGTCTGCCACCAGCCGACGGGCAAGGGCGCA
GGCGCGTTCCCGGCGCTCGACGGCAGCAAGGTCGCGAACGGCCCCCTCGCCGAGCACGTGAGCATCGTGCTGAAGGGCAA
GAATGCGATGCCGTCGTGGGCGCCGACGCTGAACGACGTCGAGATCGCTTCCGTCATCACGTTCGAACGCAATTCGTGGG
GCAACCACACGGGCGACATCCTGCAGCCGAAGCAGGTCGCCGACGCGCGCAACGGTCGTCTGCCGTCGGGCGGCGATCAC
CTCGCAGGCGCAGCAGCGGCCGCAGCATCGGACGCCGCAGCGGCGAGCGGAGCGGAAGGCGCGAGCGGCGCGCCCGCGGC
AAGCGGGGAGGCGGGCGCATCGGCTACCGCGCCAGCTTCGGGTGCATCGGACGGCGCAGCCGCTTCGGCGCCGCAGGCAT
CGCTGCCCGCCAGCGTCTACTTCGAGACCAACAAGAGCTCTCTGCCCACCGACGCGAAAGCGGCCATCGAAGCCGCCGCC
GCATACGCAAAGGCGCATCCGGACGCGAAGTTTGCGCTCTCGGGTTTCACCGACGCAACCGGTTCGGCGGATAAGAATGC
AAAGCTCGCCAAGGCGCGTGCCGAAGCCGTCCGCGATGCGCTCAAGGCGGCAGGCATCGCCGAAGACCATATTATTTTGA
AGAAGCCGGAGACGATCACGGGCGGTGCGGACGCGAAGGAAGCACGCCGTGTAGAGATCAGCCCAGCGGCCTGA

Upstream 100 bases:

>100_bases
GGCTGTGGATCCGGCAGTGCCAGGCGCAAAAAGTTGCGTATTGAATTGCGCGCCGTTCCAGAAGACGAGAGGCAGCCTTC
CAGCGGGGTCGAGGGTTTGA

Downstream 100 bases:

>100_bases
CGTGCCACAGTCAGACAAAAGCAGCATTCGATTTAGGAGATTGTCATGTCTAGCATCGGACACGATGTAGCCGCAGGGCA
CGAGCACGTGCACGGCGACC

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MEILGKEAMKTIKRALTGVLACSGLLFAGAALAVGDSPGGPRVNEINLQPPVTRIAEELYSLHTFMLILCTVIFIGVFGV
MFYSIFAHRKSKGYKAANFHESTTVEIIWTVVPFIIVVLMALPATKTVVAMKDTTNADLTVKVTGYQWKWAYDYVKGPGE
GINFFSTLTTPRAEVDGRQPITDTYLQEVDNPLVVPVNKKIRIITTANDVVHSWYVPAFGVKQDAIPGFVRDTWFRAEKV
GTYRGFCTELCGKEHAFMPVVVNVLSDEDYAKWVDDQKKKMAAGQDDPNKNYTLAELMERGGKVYSANCAVCHQPTGKGA
GAFPALDGSKVANGPLAEHVSIVLKGKNAMPSWAPTLNDVEIASVITFERNSWGNHTGDILQPKQVADARNGRLPSGGDH
LAGAAAAAASDAAAASGAEGASGAPAASGEAGASATAPASGASDGAAASAPQASLPASVYFETNKSSLPTDAKAAIEAAA
AYAKAHPDAKFALSGFTDATGSADKNAKLAKARAEAVRDALKAAGIAEDHIILKKPETITGGADAKEARRVEISPAA

Sequences:

>Translated_557_residues
MEILGKEAMKTIKRALTGVLACSGLLFAGAALAVGDSPGGPRVNEINLQPPVTRIAEELYSLHTFMLILCTVIFIGVFGV
MFYSIFAHRKSKGYKAANFHESTTVEIIWTVVPFIIVVLMALPATKTVVAMKDTTNADLTVKVTGYQWKWAYDYVKGPGE
GINFFSTLTTPRAEVDGRQPITDTYLQEVDNPLVVPVNKKIRIITTANDVVHSWYVPAFGVKQDAIPGFVRDTWFRAEKV
GTYRGFCTELCGKEHAFMPVVVNVLSDEDYAKWVDDQKKKMAAGQDDPNKNYTLAELMERGGKVYSANCAVCHQPTGKGA
GAFPALDGSKVANGPLAEHVSIVLKGKNAMPSWAPTLNDVEIASVITFERNSWGNHTGDILQPKQVADARNGRLPSGGDH
LAGAAAAAASDAAAASGAEGASGAPAASGEAGASATAPASGASDGAAASAPQASLPASVYFETNKSSLPTDAKAAIEAAA
AYAKAHPDAKFALSGFTDATGSADKNAKLAKARAEAVRDALKAAGIAEDHIILKKPETITGGADAKEARRVEISPAA
>Mature_557_residues
MEILGKEAMKTIKRALTGVLACSGLLFAGAALAVGDSPGGPRVNEINLQPPVTRIAEELYSLHTFMLILCTVIFIGVFGV
MFYSIFAHRKSKGYKAANFHESTTVEIIWTVVPFIIVVLMALPATKTVVAMKDTTNADLTVKVTGYQWKWAYDYVKGPGE
GINFFSTLTTPRAEVDGRQPITDTYLQEVDNPLVVPVNKKIRIITTANDVVHSWYVPAFGVKQDAIPGFVRDTWFRAEKV
GTYRGFCTELCGKEHAFMPVVVNVLSDEDYAKWVDDQKKKMAAGQDDPNKNYTLAELMERGGKVYSANCAVCHQPTGKGA
GAFPALDGSKVANGPLAEHVSIVLKGKNAMPSWAPTLNDVEIASVITFERNSWGNHTGDILQPKQVADARNGRLPSGGDH
LAGAAAAAASDAAAASGAEGASGAPAASGEAGASATAPASGASDGAAASAPQASLPASVYFETNKSSLPTDAKAAIEAAA
AYAKAHPDAKFALSGFTDATGSADKNAKLAKARAEAVRDALKAAGIAEDHIILKKPETITGGADAKEARRVEISPAA

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=221, Percent_Identity=34.841628959276, Blast_Score=140, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6226540, Length=224, Percent_Identity=29.9107142857143, Blast_Score=126, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 58539; Mature: 58539

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC ; PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEILGKEAMKTIKRALTGVLACSGLLFAGAALAVGDSPGGPRVNEINLQPPVTRIAEELY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCCCCCCCEEECCCCCHHHHHHHHH
SLHTFMLILCTVIFIGVFGVMFYSIFAHRKSKGYKAANFHESTTVEIIWTVVPFIIVVLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ALPATKTVVAMKDTTNADLTVKVTGYQWKWAYDYVKGPGEGINFFSTLTTPRAEVDGRQP
HCCCCCEEEEEECCCCCEEEEEEECEEEEEEEHHHCCCCCCCCHHHHCCCCCCCCCCCCC
ITDTYLQEVDNPLVVPVNKKIRIITTANDVVHSWYVPAFGVKQDAIPGFVRDTWFRAEKV
CHHHHHHHCCCCEEEECCCCEEEEEECCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHC
GTYRGFCTELCGKEHAFMPVVVNVLSDEDYAKWVDDQKKKMAAGQDDPNKNYTLAELMER
CCHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
GGKVYSANCAVCHQPTGKGAGAFPALDGSKVANGPLAEHVSIVLKGKNAMPSWAPTLNDV
CCCEEECCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHEEEEEEECCCCCCCCCCCCCCE
EIASVITFERNSWGNHTGDILQPKQVADARNGRLPSGGDHLAGAAAAAASDAAAASGAEG
EEEEEEEEECCCCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
ASGAPAASGEAGASATAPASGASDGAAASAPQASLPASVYFETNKSSLPTDAKAAIEAAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHH
AYAKAHPDAKFALSGFTDATGSADKNAKLAKARAEAVRDALKAAGIAEDHIILKKPETIT
HHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCC
GGADAKEARRVEISPAA
CCCCCCCCCEEECCCCC
>Mature Secondary Structure
MEILGKEAMKTIKRALTGVLACSGLLFAGAALAVGDSPGGPRVNEINLQPPVTRIAEELY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCCCCCCCEEECCCCCHHHHHHHHH
SLHTFMLILCTVIFIGVFGVMFYSIFAHRKSKGYKAANFHESTTVEIIWTVVPFIIVVLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ALPATKTVVAMKDTTNADLTVKVTGYQWKWAYDYVKGPGEGINFFSTLTTPRAEVDGRQP
HCCCCCEEEEEECCCCCEEEEEEECEEEEEEEHHHCCCCCCCCHHHHCCCCCCCCCCCCC
ITDTYLQEVDNPLVVPVNKKIRIITTANDVVHSWYVPAFGVKQDAIPGFVRDTWFRAEKV
CHHHHHHHCCCCEEEECCCCEEEEEECCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHC
GTYRGFCTELCGKEHAFMPVVVNVLSDEDYAKWVDDQKKKMAAGQDDPNKNYTLAELMER
CCHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
GGKVYSANCAVCHQPTGKGAGAFPALDGSKVANGPLAEHVSIVLKGKNAMPSWAPTLNDV
CCCEEECCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHEEEEEEECCCCCCCCCCCCCCE
EIASVITFERNSWGNHTGDILQPKQVADARNGRLPSGGDHLAGAAAAAASDAAAASGAEG
EEEEEEEEECCCCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
ASGAPAASGEAGASATAPASGASDGAAASAPQASLPASVYFETNKSSLPTDAKAAIEAAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHH
AYAKAHPDAKFALSGFTDATGSADKNAKLAKARAEAVRDALKAAGIAEDHIILKKPETIT
HHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCC
GGADAKEARRVEISPAA
CCCCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1648008 [H]