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The map label for this gene is yciR [C]

Identifier: 183222770

GI number: 183222770

Start: 3548162

End: 3550618

Strand: Reverse

Name: yciR [C]

Synonym: LEPBI_I3429

Alternate gene names: 183222770

Gene position: 3550618-3548162 (Counterclockwise)

Preceding gene: 183222775

Following gene: 183222769

Centisome position: 98.64

GC content: 37.65

Gene sequence:

>2457_bases
ATGTCACTGAAGCAGATCACAATCTATATTGAAGAATCTGAGCTGAATTTCTTTAACAGGCTATTACGGGACATAACAAA
CATCGATACATGCCATGTGCATAGTTTCCCATCGATCTTAAAAATCAAACCTGGAACCATACAAGACTCTGCCGTTTTTT
TATTTTGGAATGATTCCAATGCGATGGAGAAACAAAAATTTATTTTTGAACACTTTCCAGAATCACCGTATGTCATTTTA
TCCACAAATCTTCTCAGTCCCGAAGATCTCTCGCAAGTGGCACACCCAACATTCTTACATTTAGCAGAACCAACTTACTC
GGTGGGTACTTTAGATTTAGTTTTAAACTTCGCAGAACGCCTGATAGAAGACATGAACCGGTCAATTGCTTATGACAAAA
TCCGTGAAAAGGTTGTGGTCTTAGAAAACGTCTTTGAAGAATCGTTAGACGTATTGATGCAAATAGATCCAAACACCAAA
CATATCATCAATGCGAACAAACAAGCCGTCGTTGTTTTGGAATATGCGCTGGAAGAAATTGTTGGCAAAGAGTTTTCATA
CTTTATGCCACCAGTGGAAGTGGATGAAGACGCTGAGTTTGAAGGAAATTTAATCGAAAGCACGGCCTTACGAACCAAAT
CAGGCAGGTTGATACCCACAGAGTCCTCGTTTCGATTGTTTCCTGTGAATGGTAAGATGGCGATTTGGGCCACCTTTCGT
GATATCACGGATCGTAAACGTTCCCAAGAACAAGTCAAAAACCAAAAAGCTTTTTATGAATTCATTTTGGATAATTTAGA
TTCAGACATTGCCGTATTAAATTCCAATTTTGAATATGAGTATACAAATCCAGTATTTTTATCCAATCGGGAAATTCGTA
AGTGGTTGTACAAAAAAACAGATGTTGATCTAGCTGAAAAGTTGGACCTTCCTCAAGAATTTTATGAACGTAGAAAAAAA
TTCTTAGATATTGCCGCTAAAAATAATGAAATTGTCGAATTTGAAGAACTCATTCAGGACCAAAACGACAAAGTAACCTA
TTTACTTAGAAAATACATACCGATTGATGACTCAGAAACCAATCAAAAACGGTTTATTAGTTTTGGAGTTGATATCACAG
AACGAAAGTTATCCGAAGAAAGGATCACCTATCTTGCTTACTACGATGCGTTGACAGGTTTAGCAAACCGAACTTTATTC
ATCGACCATGCCAACCAAGCTCTTAAAAATCATAAATCGACGGAAACCTTACTCGCCTTCTATTTTTTTGATATCGATAA
TTTTAAATTCATCAATGACAGTTTGGGTCATACAAAAGGTGATATTTTATTACAGATGGTCGGAGCCAGACTCAAACGAG
TGATGACAGAAGTGGATACGGTGGCTCGTTTTGGTGGAGATGAATTTGCGATTCTAAAAGTGGATGTTTCGAATAAAAGT
TCAGCCGCTGAATTTGCTCAGAAGATATTAGATATATTAAGCCAACCGTTTCATATTATGGGTCGCGATTTGTTCACAAC
GATTAGTATGGGAATTGCCTTATCTCCGAATGATGGAGTGACTTCGGCAGAATTATTAAAAAATTCAGACATGGCAATGT
ATAAGGCGAAGGAACTTGGCCGAAATAATTATAAATTTTATACCAATGAACTGATATTACGTTCCGAAAAACGATTGTAC
ATCGAAAATTCACTTCGTAAAGCAATTCAAAACGAAGAATTACTCTTATTCTTCCAACCAAAAATATCGACCATCACCAA
CCAAGTTTGTGGGGCAGAAGCTCTCATCCGATGGAAGCACCCGGAACGTGGTTGGGTTCCACCAATTGAATTTATCCCGG
TGGCAGAAGACTCAGGGATCATAGAAAGGATTGGGGATTGGGTTTTGGAAGAAGCTTGTCGTTTGAAAAAACAATGGAGT
GAAAAAAATCTCCCCAGTTTTCCATTGAGTATCAATGTGAGTGGAAAACAACTTGCACGCGCTAACTGGTCGCACCGAGT
GCAGGCAACGATTTTACAATACGGAATCAATCCAGAAGAAATTGAATTGGAACTCACTGAAAGTTCTATCATGGAAAATC
CCGAAAAAAGTATCGAGGCCTTTGAATATCTCTCAGAACTAGGAATTAAAGTTTCTATTGATGATTTTGGAACTGGGTAT
AGTTCGTTAAGTTATTTAAAAAAGATCAATGCTGATGTGATAAAAATTGATCGTTCTTTCGTAGTGGACTTGGAACTGAA
TGAAGATGATAGAGCCATTTGTAAAGCCATCATCAATATGGCACATTCATTGGGACTTGAAGTGATTGCAGAAGGAGTGG
AAAATCCGGCCCAAAGGGATTTGTTACATGATTTAGGATGCCATATGATCCAAGGTTATTTGTATAGTAAACCCCTCCCT
GAAGATGAATTTGTTGTCTTTGTGCAAAAATTTAACGAATCTGCCAAAACAAAATAG

Upstream 100 bases:

>100_bases
ACAACACGCGAATGGGGAACCTTGCTTGTGCATCGCATAGGCGTATGGTTAAAAAAATCAATTGTAAGGAAAAGGATTTT
TCGTCTACTATGCCTAGGTC

Downstream 100 bases:

>100_bases
CCGAAATTTTGAATGATGGTTCGTTCTATTTCTATCCTATCCTTCATTTTATTTTTTGTCCAAGCCGTTCCCGCAGAATC
TCGCGAAGTCAAAAAGAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 818; Mature: 817

Protein sequence:

>818_residues
MSLKQITIYIEESELNFFNRLLRDITNIDTCHVHSFPSILKIKPGTIQDSAVFLFWNDSNAMEKQKFIFEHFPESPYVIL
STNLLSPEDLSQVAHPTFLHLAEPTYSVGTLDLVLNFAERLIEDMNRSIAYDKIREKVVVLENVFEESLDVLMQIDPNTK
HIINANKQAVVVLEYALEEIVGKEFSYFMPPVEVDEDAEFEGNLIESTALRTKSGRLIPTESSFRLFPVNGKMAIWATFR
DITDRKRSQEQVKNQKAFYEFILDNLDSDIAVLNSNFEYEYTNPVFLSNREIRKWLYKKTDVDLAEKLDLPQEFYERRKK
FLDIAAKNNEIVEFEELIQDQNDKVTYLLRKYIPIDDSETNQKRFISFGVDITERKLSEERITYLAYYDALTGLANRTLF
IDHANQALKNHKSTETLLAFYFFDIDNFKFINDSLGHTKGDILLQMVGARLKRVMTEVDTVARFGGDEFAILKVDVSNKS
SAAEFAQKILDILSQPFHIMGRDLFTTISMGIALSPNDGVTSAELLKNSDMAMYKAKELGRNNYKFYTNELILRSEKRLY
IENSLRKAIQNEELLLFFQPKISTITNQVCGAEALIRWKHPERGWVPPIEFIPVAEDSGIIERIGDWVLEEACRLKKQWS
EKNLPSFPLSINVSGKQLARANWSHRVQATILQYGINPEEIELELTESSIMENPEKSIEAFEYLSELGIKVSIDDFGTGY
SSLSYLKKINADVIKIDRSFVVDLELNEDDRAICKAIINMAHSLGLEVIAEGVENPAQRDLLHDLGCHMIQGYLYSKPLP
EDEFVVFVQKFNESAKTK

Sequences:

>Translated_818_residues
MSLKQITIYIEESELNFFNRLLRDITNIDTCHVHSFPSILKIKPGTIQDSAVFLFWNDSNAMEKQKFIFEHFPESPYVIL
STNLLSPEDLSQVAHPTFLHLAEPTYSVGTLDLVLNFAERLIEDMNRSIAYDKIREKVVVLENVFEESLDVLMQIDPNTK
HIINANKQAVVVLEYALEEIVGKEFSYFMPPVEVDEDAEFEGNLIESTALRTKSGRLIPTESSFRLFPVNGKMAIWATFR
DITDRKRSQEQVKNQKAFYEFILDNLDSDIAVLNSNFEYEYTNPVFLSNREIRKWLYKKTDVDLAEKLDLPQEFYERRKK
FLDIAAKNNEIVEFEELIQDQNDKVTYLLRKYIPIDDSETNQKRFISFGVDITERKLSEERITYLAYYDALTGLANRTLF
IDHANQALKNHKSTETLLAFYFFDIDNFKFINDSLGHTKGDILLQMVGARLKRVMTEVDTVARFGGDEFAILKVDVSNKS
SAAEFAQKILDILSQPFHIMGRDLFTTISMGIALSPNDGVTSAELLKNSDMAMYKAKELGRNNYKFYTNELILRSEKRLY
IENSLRKAIQNEELLLFFQPKISTITNQVCGAEALIRWKHPERGWVPPIEFIPVAEDSGIIERIGDWVLEEACRLKKQWS
EKNLPSFPLSINVSGKQLARANWSHRVQATILQYGINPEEIELELTESSIMENPEKSIEAFEYLSELGIKVSIDDFGTGY
SSLSYLKKINADVIKIDRSFVVDLELNEDDRAICKAIINMAHSLGLEVIAEGVENPAQRDLLHDLGCHMIQGYLYSKPLP
EDEFVVFVQKFNESAKTK
>Mature_817_residues
SLKQITIYIEESELNFFNRLLRDITNIDTCHVHSFPSILKIKPGTIQDSAVFLFWNDSNAMEKQKFIFEHFPESPYVILS
TNLLSPEDLSQVAHPTFLHLAEPTYSVGTLDLVLNFAERLIEDMNRSIAYDKIREKVVVLENVFEESLDVLMQIDPNTKH
IINANKQAVVVLEYALEEIVGKEFSYFMPPVEVDEDAEFEGNLIESTALRTKSGRLIPTESSFRLFPVNGKMAIWATFRD
ITDRKRSQEQVKNQKAFYEFILDNLDSDIAVLNSNFEYEYTNPVFLSNREIRKWLYKKTDVDLAEKLDLPQEFYERRKKF
LDIAAKNNEIVEFEELIQDQNDKVTYLLRKYIPIDDSETNQKRFISFGVDITERKLSEERITYLAYYDALTGLANRTLFI
DHANQALKNHKSTETLLAFYFFDIDNFKFINDSLGHTKGDILLQMVGARLKRVMTEVDTVARFGGDEFAILKVDVSNKSS
AAEFAQKILDILSQPFHIMGRDLFTTISMGIALSPNDGVTSAELLKNSDMAMYKAKELGRNNYKFYTNELILRSEKRLYI
ENSLRKAIQNEELLLFFQPKISTITNQVCGAEALIRWKHPERGWVPPIEFIPVAEDSGIIERIGDWVLEEACRLKKQWSE
KNLPSFPLSINVSGKQLARANWSHRVQATILQYGINPEEIELELTESSIMENPEKSIEAFEYLSELGIKVSIDDFGTGYS
SLSYLKKINADVIKIDRSFVVDLELNEDDRAICKAIINMAHSLGLEVIAEGVENPAQRDLLHDLGCHMIQGYLYSKPLPE
DEFVVFVQKFNESAKTK

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=492, Percent_Identity=36.1788617886179, Blast_Score=313, Evalue=2e-86,
Organism=Escherichia coli, GI87081921, Length=433, Percent_Identity=33.0254041570439, Blast_Score=237, Evalue=2e-63,
Organism=Escherichia coli, GI226510982, Length=467, Percent_Identity=29.3361884368308, Blast_Score=220, Evalue=3e-58,
Organism=Escherichia coli, GI1790496, Length=259, Percent_Identity=34.7490347490347, Blast_Score=163, Evalue=4e-41,
Organism=Escherichia coli, GI87081743, Length=260, Percent_Identity=34.6153846153846, Blast_Score=158, Evalue=1e-39,
Organism=Escherichia coli, GI1786507, Length=238, Percent_Identity=34.0336134453782, Blast_Score=149, Evalue=6e-37,
Organism=Escherichia coli, GI1787055, Length=247, Percent_Identity=36.0323886639676, Blast_Score=147, Evalue=3e-36,
Organism=Escherichia coli, GI1788502, Length=254, Percent_Identity=32.2834645669291, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI87081845, Length=246, Percent_Identity=32.9268292682927, Blast_Score=136, Evalue=5e-33,
Organism=Escherichia coli, GI87081980, Length=255, Percent_Identity=31.3725490196078, Blast_Score=134, Evalue=3e-32,
Organism=Escherichia coli, GI1788849, Length=253, Percent_Identity=32.4110671936759, Blast_Score=133, Evalue=6e-32,
Organism=Escherichia coli, GI87082096, Length=250, Percent_Identity=34.8, Blast_Score=132, Evalue=9e-32,
Organism=Escherichia coli, GI1788381, Length=585, Percent_Identity=23.7606837606838, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1788956, Length=155, Percent_Identity=36.7741935483871, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI87081881, Length=173, Percent_Identity=35.8381502890173, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI87081977, Length=156, Percent_Identity=31.4102564102564, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787410, Length=120, Percent_Identity=35.8333333333333, Blast_Score=78, Evalue=3e-15,
Organism=Escherichia coli, GI1786584, Length=183, Percent_Identity=31.6939890710383, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1789650, Length=427, Percent_Identity=20.3747072599532, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787816, Length=191, Percent_Identity=29.3193717277487, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787262, Length=163, Percent_Identity=28.8343558282209, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI145693134, Length=271, Percent_Identity=28.7822878228782, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI87082007, Length=169, Percent_Identity=28.9940828402367, Blast_Score=70, Evalue=8e-13,
Organism=Escherichia coli, GI87081974, Length=150, Percent_Identity=32.6666666666667, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787802, Length=169, Percent_Identity=30.1775147928994, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 94122; Mature: 93991

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF ; PS00284 SERPIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKQITIYIEESELNFFNRLLRDITNIDTCHVHSFPSILKIKPGTIQDSAVFLFWNDSN
CCCEEEEEEEECCHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCCEEEEEECCCC
AMEKQKFIFEHFPESPYVILSTNLLSPEDLSQVAHPTFLHLAEPTYSVGTLDLVLNFAER
CHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHH
LIEDMNRSIAYDKIREKVVVLENVFEESLDVLMQIDPNTKHIINANKQAVVVLEYALEEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEECCCCCEEEEHHHHHHHH
VGKEFSYFMPPVEVDEDAEFEGNLIESTALRTKSGRLIPTESSFRLFPVNGKMAIWATFR
HCCCHHHCCCCCCCCCCCCCCCCEEHHHHEECCCCCEEECCCCCEEEECCCCEEEEEEHH
DITDRKRSQEQVKNQKAFYEFILDNLDSDIAVLNSNFEYEYTNPVFLSNREIRKWLYKKT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEECCCEEECCHHHHHHHHHCC
DVDLAEKLDLPQEFYERRKKFLDIAAKNNEIVEFEELIQDQNDKVTYLLRKYIPIDDSET
CCCHHHHCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHCCCCCHHHHHHHHHCCCCCCCC
NQKRFISFGVDITERKLSEERITYLAYYDALTGLANRTLFIDHANQALKNHKSTETLLAF
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHCCCCHHHEEEE
YFFDIDNFKFINDSLGHTKGDILLQMVGARLKRVMTEVDTVARFGGDEFAILKVDVSNKS
EEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCC
SAAEFAQKILDILSQPFHIMGRDLFTTISMGIALSPNDGVTSAELLKNSDMAMYKAKELG
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCEEECCCCCCCHHHHHCCCCHHHHHHHHCC
RNNYKFYTNELILRSEKRLYIENSLRKAIQNEELLLFFQPKISTITNQVCGAEALIRWKH
CCCCEEEECEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCHHHEEECC
PERGWVPPIEFIPVAEDSGIIERIGDWVLEEACRLKKQWSEKNLPSFPLSINVSGKQLAR
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHH
ANWSHRVQATILQYGINPEEIELELTESSIMENPEKSIEAFEYLSELGIKVSIDDFGTGY
CCCCHHHHHHHHHHCCCHHHEEEEEEHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCH
SSLSYLKKINADVIKIDRSFVVDLELNEDDRAICKAIINMAHSLGLEVIAEGVENPAQRD
HHHHHHHHCCCCEEEECCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LLHDLGCHMIQGYLYSKPLPEDEFVVFVQKFNESAKTK
HHHHHHHHHHHHHHHCCCCCCCHHEEEEEHHCCCCCCC
>Mature Secondary Structure 
SLKQITIYIEESELNFFNRLLRDITNIDTCHVHSFPSILKIKPGTIQDSAVFLFWNDSN
CCEEEEEEEECCHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCCEEEEEECCCC
AMEKQKFIFEHFPESPYVILSTNLLSPEDLSQVAHPTFLHLAEPTYSVGTLDLVLNFAER
CHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHH
LIEDMNRSIAYDKIREKVVVLENVFEESLDVLMQIDPNTKHIINANKQAVVVLEYALEEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEECCCCCEEEEHHHHHHHH
VGKEFSYFMPPVEVDEDAEFEGNLIESTALRTKSGRLIPTESSFRLFPVNGKMAIWATFR
HCCCHHHCCCCCCCCCCCCCCCCEEHHHHEECCCCCEEECCCCCEEEECCCCEEEEEEHH
DITDRKRSQEQVKNQKAFYEFILDNLDSDIAVLNSNFEYEYTNPVFLSNREIRKWLYKKT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEECCCEEECCHHHHHHHHHCC
DVDLAEKLDLPQEFYERRKKFLDIAAKNNEIVEFEELIQDQNDKVTYLLRKYIPIDDSET
CCCHHHHCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHCCCCCHHHHHHHHHCCCCCCCC
NQKRFISFGVDITERKLSEERITYLAYYDALTGLANRTLFIDHANQALKNHKSTETLLAF
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHCCCCHHHEEEE
YFFDIDNFKFINDSLGHTKGDILLQMVGARLKRVMTEVDTVARFGGDEFAILKVDVSNKS
EEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCC
SAAEFAQKILDILSQPFHIMGRDLFTTISMGIALSPNDGVTSAELLKNSDMAMYKAKELG
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCEEECCCCCCCHHHHHCCCCHHHHHHHHCC
RNNYKFYTNELILRSEKRLYIENSLRKAIQNEELLLFFQPKISTITNQVCGAEALIRWKH
CCCCEEEECEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCHHHEEECC
PERGWVPPIEFIPVAEDSGIIERIGDWVLEEACRLKKQWSEKNLPSFPLSINVSGKQLAR
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHH
ANWSHRVQATILQYGINPEEIELELTESSIMENPEKSIEAFEYLSELGIKVSIDDFGTGY
CCCCHHHHHHHHHHCCCHHHEEEEEEHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCH
SSLSYLKKINADVIKIDRSFVVDLELNEDDRAICKAIINMAHSLGLEVIAEGVENPAQRD
HHHHHHHHCCCCEEEECCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LLHDLGCHMIQGYLYSKPLPEDEFVVFVQKFNESAKTK
HHHHHHHHHHHHHHHCCCCCCCHHEEEEEHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]