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The map label for this gene is aroC

Identifier: 183222750

GI number: 183222750

Start: 3528236

End: 3529372

Strand: Reverse

Name: aroC

Synonym: LEPBI_I3408

Alternate gene names: 183222750

Gene position: 3529372-3528236 (Counterclockwise)

Preceding gene: 183222755

Following gene: 183222749

Centisome position: 98.05

GC content: 44.33

Gene sequence:

>1137_bases
ATGCCATCAAGTTGGGGAAAAATTTTTCGAGTATCGACCTTTGGAGAGTCTCACGGAACATCCGTCGGAGTGGTTGTGGA
TGGAGTGCCTGCGGGCCTTCCGTTTCCAGAAGAAGAAATCCAAAAAGATCTAACACGCCGTAGACCAGGTCAAAATGACC
TCACCACACCGAGAGATGAAAAGGACCGTATGGTCGTTGAGTCTGGAGTGTTTGAAGGCAAAACCACTGGGAGTCCCATC
CTCATGAAGGTGAACAACCAAAATACGATTGGAAGTGATTATGACGAGATGGCACATGTCTTCCGTCCTTCCCATGCAGA
TTATACCTACTCTGAAAAATATGGCCATAGAGCCCATGTGGGTGGAGGTCGCTCTTCTGTTCGCGAAACCATTGGTCGGG
TTGCCGCAGCGGGACTGGCTCGTGTCATCTTAGAAAATGAATTGGGAATTTCTACGGTTGGTTTTGTGGATTCAATTGGT
CCTATCGACTCTAATATTACGGAAGATGAATATCCCATCTCACGAGATTTGGTAGACCAATTTCCCACACGTTGTCCAAA
AGCATCAGCGAACGAAGAAATGGAAACACTCATTCGTAAACTCCGTGATGAAGGAGATTCTGTTGGTGGAGTGGTGAAGG
TGGTTGTGAGAAACCTTCCTCCAGGTCTTGGTGATCCCGTTTACGATAAGTTAGATGCTGATTTGGCAAAAGCAATTCTT
TCCATTTCTGCCTGTAAGGGTTTTGAAGTAGGATCTGGTTTTTCTGGTACTCGCCAAACAGGCAGTACACACAATGATGA
ATTTTACATAGAAGAAGGCACTGGCAAAGTGAAAACACGGACCAATCGTTCTGGTGGAATCCAAGGTGGAATCTCCAATG
GAATGGATCTTGTGATTCGTGCTGCTTTCAAACCAACATCCACTATCAAAAAAGAACAAAAAACAATCAACGATCAAAAC
AAGGAAACCATTCTGAAAGCAAAAGGTCGTCACGACCCATGTGTACTTCCGAGAGCGGTGCCCATTGTGGAAGCAGTTGT
CAATTTAGTGTTAGTCGATGCGTATTTATACCAAAGAGCCTTACAACCAAAATGGTTCATGAAGTATGCAAATTTAAATG
CAATTCCAAACCAATAA

Upstream 100 bases:

>100_bases
GCAATTGCCTTATATTTGGGTCCATTGAAGATTGAGTGCATTCCAAGTTCATGAAAAACTTTATTGGAGAGAATGCAATC
TCCATTTTCATTGTCCGTAT

Downstream 100 bases:

>100_bases
GGACCGATAACCGATGAACCGTCCCAAAGTATATAAAATTTTACTCCTTGAAGACGATGAAAGTAGCGCAAAACTTTTAT
TACACACTTTGGAACGTTAC

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MPSSWGKIFRVSTFGESHGTSVGVVVDGVPAGLPFPEEEIQKDLTRRRPGQNDLTTPRDEKDRMVVESGVFEGKTTGSPI
LMKVNNQNTIGSDYDEMAHVFRPSHADYTYSEKYGHRAHVGGGRSSVRETIGRVAAAGLARVILENELGISTVGFVDSIG
PIDSNITEDEYPISRDLVDQFPTRCPKASANEEMETLIRKLRDEGDSVGGVVKVVVRNLPPGLGDPVYDKLDADLAKAIL
SISACKGFEVGSGFSGTRQTGSTHNDEFYIEEGTGKVKTRTNRSGGIQGGISNGMDLVIRAAFKPTSTIKKEQKTINDQN
KETILKAKGRHDPCVLPRAVPIVEAVVNLVLVDAYLYQRALQPKWFMKYANLNAIPNQ

Sequences:

>Translated_378_residues
MPSSWGKIFRVSTFGESHGTSVGVVVDGVPAGLPFPEEEIQKDLTRRRPGQNDLTTPRDEKDRMVVESGVFEGKTTGSPI
LMKVNNQNTIGSDYDEMAHVFRPSHADYTYSEKYGHRAHVGGGRSSVRETIGRVAAAGLARVILENELGISTVGFVDSIG
PIDSNITEDEYPISRDLVDQFPTRCPKASANEEMETLIRKLRDEGDSVGGVVKVVVRNLPPGLGDPVYDKLDADLAKAIL
SISACKGFEVGSGFSGTRQTGSTHNDEFYIEEGTGKVKTRTNRSGGIQGGISNGMDLVIRAAFKPTSTIKKEQKTINDQN
KETILKAKGRHDPCVLPRAVPIVEAVVNLVLVDAYLYQRALQPKWFMKYANLNAIPNQ
>Mature_377_residues
PSSWGKIFRVSTFGESHGTSVGVVVDGVPAGLPFPEEEIQKDLTRRRPGQNDLTTPRDEKDRMVVESGVFEGKTTGSPIL
MKVNNQNTIGSDYDEMAHVFRPSHADYTYSEKYGHRAHVGGGRSSVRETIGRVAAAGLARVILENELGISTVGFVDSIGP
IDSNITEDEYPISRDLVDQFPTRCPKASANEEMETLIRKLRDEGDSVGGVVKVVVRNLPPGLGDPVYDKLDADLAKAILS
ISACKGFEVGSGFSGTRQTGSTHNDEFYIEEGTGKVKTRTNRSGGIQGGISNGMDLVIRAAFKPTSTIKKEQKTINDQNK
ETILKAKGRHDPCVLPRAVPIVEAVVNLVLVDAYLYQRALQPKWFMKYANLNAIPNQ

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=370, Percent_Identity=45.1351351351351, Blast_Score=291, Evalue=6e-80,
Organism=Saccharomyces cerevisiae, GI6321290, Length=368, Percent_Identity=53.5326086956522, Blast_Score=378, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_LEPBA (B0SHV8)

Other databases:

- EMBL:   CP000777
- RefSeq:   YP_001964337.1
- ProteinModelPortal:   B0SHV8
- SMR:   B0SHV8
- GeneID:   6389011
- GenomeReviews:   CP000777_GR
- KEGG:   lbf:LBF_3292
- HOGENOM:   HBG292336
- OMA:   FIVWNEN
- ProtClustDB:   PRK05382
- BioCyc:   LBIF355278:LBF_3292-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 41220; Mature: 41089

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSSWGKIFRVSTFGESHGTSVGVVVDGVPAGLPFPEEEIQKDLTRRRPGQNDLTTPRDE
CCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCC
KDRMVVESGVFEGKTTGSPILMKVNNQNTIGSDYDEMAHVFRPSHADYTYSEKYGHRAHV
CCCEEHHCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCCCHHHHCCCCCCC
GGGRSSVRETIGRVAAAGLARVILENELGISTVGFVDSIGPIDSNITEDEYPISRDLVDQ
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
FPTRCPKASANEEMETLIRKLRDEGDSVGGVVKVVVRNLPPGLGDPVYDKLDADLAKAIL
HHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
SISACKGFEVGSGFSGTRQTGSTHNDEFYIEEGTGKVKTRTNRSGGIQGGISNGMDLVIR
HHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCEEEEE
AAFKPTSTIKKEQKTINDQNKETILKAKGRHDPCVLPRAVPIVEAVVNLVLVDAYLYQRA
ECCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LQPKWFMKYANLNAIPNQ
CCHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PSSWGKIFRVSTFGESHGTSVGVVVDGVPAGLPFPEEEIQKDLTRRRPGQNDLTTPRDE
CCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCC
KDRMVVESGVFEGKTTGSPILMKVNNQNTIGSDYDEMAHVFRPSHADYTYSEKYGHRAHV
CCCEEHHCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCCCHHHHCCCCCCC
GGGRSSVRETIGRVAAAGLARVILENELGISTVGFVDSIGPIDSNITEDEYPISRDLVDQ
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
FPTRCPKASANEEMETLIRKLRDEGDSVGGVVKVVVRNLPPGLGDPVYDKLDADLAKAIL
HHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
SISACKGFEVGSGFSGTRQTGSTHNDEFYIEEGTGKVKTRTNRSGGIQGGISNGMDLVIR
HHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCEEEEE
AAFKPTSTIKKEQKTINDQNKETILKAKGRHDPCVLPRAVPIVEAVVNLVLVDAYLYQRA
ECCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LQPKWFMKYANLNAIPNQ
CCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA