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The map label for this gene is dhaR [H]

Identifier: 183222699

GI number: 183222699

Start: 3466480

End: 3467061

Strand: Reverse

Name: dhaR [H]

Synonym: LEPBI_I3355

Alternate gene names: 183222699

Gene position: 3467061-3466480 (Counterclockwise)

Preceding gene: 183222703

Following gene: 183222698

Centisome position: 96.32

GC content: 36.77

Gene sequence:

>582_bases
ATGAAAAAGGAACCAACTAAACTACGACTCCTGTCCGTAAGCCGTAACCTTTTTCTGAGACAAGGTTATTCGGAAACTGG
TTTGAACCAAATCGTTGACGAAGCAAAAACCGTAAAAGCAAGTTTGTACCAACATTTTTCTTCCAAAGAAGAACTTGGAA
AAGAAGTCCTTAAACTTTATTCAGACGAAAATTTAAATCTCCTCAAAACTTTGATGAAACGAAATCCAAAACCTTTGGAT
TTTATCAAGGCATGGGTACGAATCTTAACACGGGAAGCACGACAATCACAATTGTTCGGATGTGGGATGGCAAACTTTCG
TGCTCAGATTAGTCCAGTAGAAACACAAATACGTTCTGAAATCGAAAGGATCGCAAACGAGACCATCGAATGTTTGACAG
AATTTTTAAAAGAATCAATTCAGAATGGATACATAAAACCTGACGTGAACCCATCTACACTCGCAAAACAGTTGTTTATT
GTCTATGAAGGTGTATTACAAAGTTACCGTCTTTTGGATGATAAAAAGTCTTTAGATGAATTGTATAAAATTGCAGAAAA
CCTAATCCCAATCCCCGAATGA

Upstream 100 bases:

>100_bases
AATTTCCCATGATGGCAGTTCTAAACTGTAGATAAAATTTGGACAGACCGGTTGGTGTATTTCTTGCTAGGATTTTGTTT
TTCCTCAATTTAGGATAAAA

Downstream 100 bases:

>100_bases
AATTAATTCCTATCAGATTATTTCATTGTGTTCTATGTTTCACTCTTTTGGTATTTTTTTTGGAAACCAATGCATTGTAC
GCGGAGGGAAAACTCGAAGT

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MKKEPTKLRLLSVSRNLFLRQGYSETGLNQIVDEAKTVKASLYQHFSSKEELGKEVLKLYSDENLNLLKTLMKRNPKPLD
FIKAWVRILTREARQSQLFGCGMANFRAQISPVETQIRSEIERIANETIECLTEFLKESIQNGYIKPDVNPSTLAKQLFI
VYEGVLQSYRLLDDKKSLDELYKIAENLIPIPE

Sequences:

>Translated_193_residues
MKKEPTKLRLLSVSRNLFLRQGYSETGLNQIVDEAKTVKASLYQHFSSKEELGKEVLKLYSDENLNLLKTLMKRNPKPLD
FIKAWVRILTREARQSQLFGCGMANFRAQISPVETQIRSEIERIANETIECLTEFLKESIQNGYIKPDVNPSTLAKQLFI
VYEGVLQSYRLLDDKKSLDELYKIAENLIPIPE
>Mature_193_residues
MKKEPTKLRLLSVSRNLFLRQGYSETGLNQIVDEAKTVKASLYQHFSSKEELGKEVLKLYSDENLNLLKTLMKRNPKPLD
FIKAWVRILTREARQSQLFGCGMANFRAQISPVETQIRSEIERIANETIECLTEFLKESIQNGYIKPDVNPSTLAKQLFI
VYEGVLQSYRLLDDKKSLDELYKIAENLIPIPE

Specific function: Transcriptional repressor for the dhaA haloalkane dehalogenase gene [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22297; Mature: 22297

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEPTKLRLLSVSRNLFLRQGYSETGLNQIVDEAKTVKASLYQHFSSKEELGKEVLKLY
CCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
SDENLNLLKTLMKRNPKPLDFIKAWVRILTREARQSQLFGCGMANFRAQISPVETQIRSE
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHH
IERIANETIECLTEFLKESIQNGYIKPDVNPSTLAKQLFIVYEGVLQSYRLLDDKKSLDE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYKIAENLIPIPE
HHHHHHHCCCCCC
>Mature Secondary Structure
MKKEPTKLRLLSVSRNLFLRQGYSETGLNQIVDEAKTVKASLYQHFSSKEELGKEVLKLY
CCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
SDENLNLLKTLMKRNPKPLDFIKAWVRILTREARQSQLFGCGMANFRAQISPVETQIRSE
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHH
IERIANETIECLTEFLKESIQNGYIKPDVNPSTLAKQLFIVYEGVLQSYRLLDDKKSLDE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYKIAENLIPIPE
HHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10735862 [H]