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The map label for this gene is mrdB [H]

Identifier: 183222422

GI number: 183222422

Start: 3186496

End: 3188010

Strand: Direct

Name: mrdB [H]

Synonym: LEPBI_I3076

Alternate gene names: 183222422

Gene position: 3186496-3188010 (Clockwise)

Preceding gene: 183222421

Following gene: 183222423

Centisome position: 88.52

GC content: 42.97

Gene sequence:

>1515_bases
ATGGCTGATCGTAATACCGAAAAACTCGATTATTTTTTAATCTTTTCCGTTGTGCTCGTGGCAATGGCTGGAGTTCTCAC
ACTCTACACACAAGAGGCCAACACTGCCGATGGATTGGGCCGATGGTACAAACAGTTTTCATTTGTGTTTGTGGGTCTCA
TTGCCATGTGGTTTATGTCAAGGATCAACTACCAGTTGATTGGATCTTACGCCCTTTTCATATACCTCTTTGCGATTTTC
CTACTTGTACTCACCCTCATCCCTGGGATTGGTTACCTTCCTTCTGGACGTGGGGCAAGGTCATGGTTAAAACTGGGTCC
GATCACCTTACAAGCATCAGAGTTCTCGAAATTGGCAACAGTGATTTTACTTGGTCAGTATCTTGTGATGAAAGAAAAGG
AAATGCACAAAATTACGGTTCTCATCATACCGTTTATCATTTGTTTGGTGCCGATGCTTTTTATCATCTTACAACCAGAC
TTTGGAACTGCTGTTTCCTTTTTACCAATGTTATTCACCATGTTGTACTTAGGTGGGGCTGATATTTTACACGTTGGATC
CCTTCTCACCTTTGGTGGGATTTCTCTTATGGTGCCCATGTACCTTGCTTACTCACAACTCACACTCATCCAACCACTCG
TTGATTTACTCCGAAAAGATAACAAAACAGAACTCGTATCACTTGTGAACCAACTCCAAGGGAAAATTTGGCTCATCTTA
GATGGGAAAAAAGTATCAGGCCTCACACTGCCTGGGATCGAAAATCCCAAAAACTTACAGATGATCCGTGAAGCCGCTGA
CATCGTCAAAGATGAATATGCAAGTATCGGGTATAAAATTTTATCCAATGAAGCCTTTATGTTTGGGCTTGGTGGCACAC
TAGCACTCATTAGTTTAGTGATGATTTTCATTCGGATCGCACGAGGATCAAGGCATCTTAGAAATTATTATATCACGATT
GGAATTCTAGGGCTTTCTGTTCTCTCTGCCATTGCCGTTCACAAATCCATTCCATTCCGTGAAAACCAAGTGATCCGACT
CACTGCCTTTTTAAACCCAGACCAGTTCAAACAAGGGGCCGGTTACCAACTCCGTGCCTCCAAACCAGCTGTAGGTTCTG
GTAAGGTGTTTGGAAAGGGACTTTTTCATGGTGAGATGACAGAAGGCCGAATCCCCCATGTTCCCGAATCGGGAACAGAC
TTTATCTTTGCTTCTTGGGCAGAACAAACTGGATTTTTTGGAAGTGTATTGTTATTATTTTTTCTCATGTCCATCCCACT
CCGAGGACTTCAAATCAGTTTTGAAAGTAAAGACAGGTTTGGATCCCTACTGGCTGCAGGGATTGTAGCGATGATCTTTT
TCCATATTGCCATCAATGTGGGGATTGTGATTGGACTTCTCCCGGTCACAGGGGTTCCACTTACCTTTATGAGTTATGGT
GGATCGCATTTGGTGATGGCGATGACAGCCGTTGGTATCATTCTATCGATTAAAAAACGTAAGTTCGCCAACTAA

Upstream 100 bases:

>100_bases
TCTTTAAGGCCGCATTCCCACCAGGATCTTTCCCTAGAACCGATAGGTCCCGTGTGAAAACCATGGAAGAAGAAGCACCA
GTCGAACAAGAGGCATTTTA

Downstream 100 bases:

>100_bases
CAAACATCATGAAACCCACCAAAAAAATTCTGGATGCAGATGAGTTCTTCCAAACCAAAGTGAAATTGGAAGAGGAACTC
ATCCGACTGGAAACTTTGGA

Product: rod shape-determining protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 503

Protein sequence:

>504_residues
MADRNTEKLDYFLIFSVVLVAMAGVLTLYTQEANTADGLGRWYKQFSFVFVGLIAMWFMSRINYQLIGSYALFIYLFAIF
LLVLTLIPGIGYLPSGRGARSWLKLGPITLQASEFSKLATVILLGQYLVMKEKEMHKITVLIIPFIICLVPMLFIILQPD
FGTAVSFLPMLFTMLYLGGADILHVGSLLTFGGISLMVPMYLAYSQLTLIQPLVDLLRKDNKTELVSLVNQLQGKIWLIL
DGKKVSGLTLPGIENPKNLQMIREAADIVKDEYASIGYKILSNEAFMFGLGGTLALISLVMIFIRIARGSRHLRNYYITI
GILGLSVLSAIAVHKSIPFRENQVIRLTAFLNPDQFKQGAGYQLRASKPAVGSGKVFGKGLFHGEMTEGRIPHVPESGTD
FIFASWAEQTGFFGSVLLLFFLMSIPLRGLQISFESKDRFGSLLAAGIVAMIFFHIAINVGIVIGLLPVTGVPLTFMSYG
GSHLVMAMTAVGIILSIKKRKFAN

Sequences:

>Translated_504_residues
MADRNTEKLDYFLIFSVVLVAMAGVLTLYTQEANTADGLGRWYKQFSFVFVGLIAMWFMSRINYQLIGSYALFIYLFAIF
LLVLTLIPGIGYLPSGRGARSWLKLGPITLQASEFSKLATVILLGQYLVMKEKEMHKITVLIIPFIICLVPMLFIILQPD
FGTAVSFLPMLFTMLYLGGADILHVGSLLTFGGISLMVPMYLAYSQLTLIQPLVDLLRKDNKTELVSLVNQLQGKIWLIL
DGKKVSGLTLPGIENPKNLQMIREAADIVKDEYASIGYKILSNEAFMFGLGGTLALISLVMIFIRIARGSRHLRNYYITI
GILGLSVLSAIAVHKSIPFRENQVIRLTAFLNPDQFKQGAGYQLRASKPAVGSGKVFGKGLFHGEMTEGRIPHVPESGTD
FIFASWAEQTGFFGSVLLLFFLMSIPLRGLQISFESKDRFGSLLAAGIVAMIFFHIAINVGIVIGLLPVTGVPLTFMSYG
GSHLVMAMTAVGIILSIKKRKFAN
>Mature_503_residues
ADRNTEKLDYFLIFSVVLVAMAGVLTLYTQEANTADGLGRWYKQFSFVFVGLIAMWFMSRINYQLIGSYALFIYLFAIFL
LVLTLIPGIGYLPSGRGARSWLKLGPITLQASEFSKLATVILLGQYLVMKEKEMHKITVLIIPFIICLVPMLFIILQPDF
GTAVSFLPMLFTMLYLGGADILHVGSLLTFGGISLMVPMYLAYSQLTLIQPLVDLLRKDNKTELVSLVNQLQGKIWLILD
GKKVSGLTLPGIENPKNLQMIREAADIVKDEYASIGYKILSNEAFMFGLGGTLALISLVMIFIRIARGSRHLRNYYITIG
ILGLSVLSAIAVHKSIPFRENQVIRLTAFLNPDQFKQGAGYQLRASKPAVGSGKVFGKGLFHGEMTEGRIPHVPESGTDF
IFASWAEQTGFFGSVLLLFFLMSIPLRGLQISFESKDRFGSLLAAGIVAMIFFHIAINVGIVIGLLPVTGVPLTFMSYGG
SHLVMAMTAVGIILSIKKRKFAN

Specific function: May play an essential role not only during sporulation, but also during vegetative growth [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=162, Percent_Identity=40.1234567901235, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1786277, Length=182, Percent_Identity=35.1648351648352, Blast_Score=102, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437
- InterPro:   IPR013438 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 55630; Mature: 55499

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ADRNTEKLDYFLIFSVVLVAMAGVLTLYTQEANTADGLGRWYKQFSFVFVGLIAMWFMS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RINYQLIGSYALFIYLFAIFLLVLTLIPGIGYLPSGRGARSWLKLGPITLQASEFSKLAT
HCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHEECCEEEEHHHHHHHHH
VILLGQYLVMKEKEMHKITVLIIPFIICLVPMLFIILQPDFGTAVSFLPMLFTMLYLGGA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCC
DILHVGSLLTFGGISLMVPMYLAYSQLTLIQPLVDLLRKDNKTELVSLVNQLQGKIWLIL
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEEE
DGKKVSGLTLPGIENPKNLQMIREAADIVKDEYASIGYKILSNEAFMFGLGGTLALISLV
CCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHCCCCEEEEECCHHHHHHHHH
MIFIRIARGSRHLRNYYITIGILGLSVLSAIAVHKSIPFRENQVIRLTAFLNPDQFKQGA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHCCC
GYQLRASKPAVGSGKVFGKGLFHGEMTEGRIPHVPESGTDFIFASWAEQTGFFGSVLLLF
CEEEECCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEEECHHHCCHHHHHHHHH
FLMSIPLRGLQISFESKDRFGSLLAAGIVAMIFFHIAINVGIVIGLLPVTGVPLTFMSYG
HHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCC
GSHLVMAMTAVGIILSIKKRKFAN
CCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2115675; 3098901; 9384377; 8436954; 1391053 [H]