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The map label for this gene is ubiE [C]

Identifier: 183222386

GI number: 183222386

Start: 3155051

End: 3155785

Strand: Direct

Name: ubiE [C]

Synonym: LEPBI_I3040

Alternate gene names: 183222386

Gene position: 3155051-3155785 (Clockwise)

Preceding gene: 183222385

Following gene: 183222387

Centisome position: 87.65

GC content: 43.95

Gene sequence:

>735_bases
ATGCCCAGGTTATCCGCGCAGGCCAACCTCCTGAAACTCCTACTCGAGCCATACCTAGATTCGATTGGCTATGAGAAAGA
AGTGGGGACGGCACTCGATGCGGGAGCAGGTCCTGGAGTTCTTACCAGTTTTCTCATGAAAAAAAATCCCAACCTCAAAT
GGATGGCCTGTGACATCTCCGAGGATATGGTGCAATATTGCAAATTGGTCTATCCAAAAGTAGACTGGAAGGTCTCCGAT
GTCCGTGCTTTGGATTATCCGGACAACCATTTTGATTTTATTTTTAATTCCATGGTCCTCATCCACATCAAAGAACCGGA
AAAAGCGTTAAAAGAATTCTATCGTGTGTTAAAACCTGGCGGGAAAATCCTCATCCACTGCCCCAATGACAAATCGTTCA
CAGGCCCGCAGGTCCTCTTAGATATGGTAGCAAAACATGCCACCATCCATCCTGCCGATCGATTTGTGATGGAAAAAGTT
CCAGGGATCATGGAGAGCTTAGGATTCCAGTTGAAACACCGAACCGATTTTATCGCTTCCAACGATGGAAATGATGACAA
ACCAATGGTAGACTATCCAAAAATTCATTTGGGAATGATGACTGGTTGGTCTATGATGTCGTTTATGGGACACCCAGAAG
GGATGCAGGATTTGTATTCCAAGTTACAGTCCGAGTATATGTCCAATCGTGTGAAATTCACGATCAAATTAGAAACACAT
TTGTACCAAAAATAA

Upstream 100 bases:

>100_bases
GACCTATTTTGAAAAAGAGTTCTTTATTTAGAACCACTCCTCTGGCGAATTCACTTTGAGCGAAAACCTTTACACACAGA
AAATATCCATCCAGGATGAA

Downstream 100 bases:

>100_bases
ACGGAGGCAAAATTGAACCAAAAGGCACCCATCATCATTGGTGAATACCACATCATTCCAGAGAATTTGCCTGCGGATGG
CCAACTTCGATTGGTATTCC

Product: hypothetical protein

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: Methyltransferase Type; Ubiquinone/Menaquinone Biosynthesis Methyltransferase

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MPRLSAQANLLKLLLEPYLDSIGYEKEVGTALDAGAGPGVLTSFLMKKNPNLKWMACDISEDMVQYCKLVYPKVDWKVSD
VRALDYPDNHFDFIFNSMVLIHIKEPEKALKEFYRVLKPGGKILIHCPNDKSFTGPQVLLDMVAKHATIHPADRFVMEKV
PGIMESLGFQLKHRTDFIASNDGNDDKPMVDYPKIHLGMMTGWSMMSFMGHPEGMQDLYSKLQSEYMSNRVKFTIKLETH
LYQK

Sequences:

>Translated_244_residues
MPRLSAQANLLKLLLEPYLDSIGYEKEVGTALDAGAGPGVLTSFLMKKNPNLKWMACDISEDMVQYCKLVYPKVDWKVSD
VRALDYPDNHFDFIFNSMVLIHIKEPEKALKEFYRVLKPGGKILIHCPNDKSFTGPQVLLDMVAKHATIHPADRFVMEKV
PGIMESLGFQLKHRTDFIASNDGNDDKPMVDYPKIHLGMMTGWSMMSFMGHPEGMQDLYSKLQSEYMSNRVKFTIKLETH
LYQK
>Mature_243_residues
PRLSAQANLLKLLLEPYLDSIGYEKEVGTALDAGAGPGVLTSFLMKKNPNLKWMACDISEDMVQYCKLVYPKVDWKVSDV
RALDYPDNHFDFIFNSMVLIHIKEPEKALKEFYRVLKPGGKILIHCPNDKSFTGPQVLLDMVAKHATIHPADRFVMEKVP
GIMESLGFQLKHRTDFIASNDGNDDKPMVDYPKIHLGMMTGWSMMSFMGHPEGMQDLYSKLQSEYMSNRVKFTIKLETHL
YQK

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 27881; Mature: 27750

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
6.6 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRLSAQANLLKLLLEPYLDSIGYEKEVGTALDAGAGPGVLTSFLMKKNPNLKWMACDIS
CCCCCHHHHHHHHHHHHHHHHCCCCHHHCCHHCCCCCHHHHHHHHHHCCCCCEEEEECCC
EDMVQYCKLVYPKVDWKVSDVRALDYPDNHFDFIFNSMVLIHIKEPEKALKEFYRVLKPG
HHHHHHHHHHCCCCCCEECCEEEECCCCCHHHHHHCCEEEEEECCHHHHHHHHHHHHCCC
GKILIHCPNDKSFTGPQVLLDMVAKHATIHPADRFVMEKVPGIMESLGFQLKHRTDFIAS
CEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCEEEC
NDGNDDKPMVDYPKIHLGMMTGWSMMSFMGHPEGMQDLYSKLQSEYMSNRVKFTIKLETH
CCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEEEECC
LYQK
CCCC
>Mature Secondary Structure 
PRLSAQANLLKLLLEPYLDSIGYEKEVGTALDAGAGPGVLTSFLMKKNPNLKWMACDIS
CCCCHHHHHHHHHHHHHHHHCCCCHHHCCHHCCCCCHHHHHHHHHHCCCCCEEEEECCC
EDMVQYCKLVYPKVDWKVSDVRALDYPDNHFDFIFNSMVLIHIKEPEKALKEFYRVLKPG
HHHHHHHHHHCCCCCCEECCEEEECCCCCHHHHHHCCEEEEEECCHHHHHHHHHHHHCCC
GKILIHCPNDKSFTGPQVLLDMVAKHATIHPADRFVMEKVPGIMESLGFQLKHRTDFIAS
CEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCEEEC
NDGNDDKPMVDYPKIHLGMMTGWSMMSFMGHPEGMQDLYSKLQSEYMSNRVKFTIKLETH
CCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEEEECC
LYQK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA