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The map label for this gene is lytS [H]

Identifier: 183222368

GI number: 183222368

Start: 3133398

End: 3135311

Strand: Direct

Name: lytS [H]

Synonym: LEPBI_I3022

Alternate gene names: 183222368

Gene position: 3133398-3135311 (Clockwise)

Preceding gene: 183222367

Following gene: 183222380

Centisome position: 87.05

GC content: 30.3

Gene sequence:

>1914_bases
ATGGGAGTTGCAATAAGCAGATTTTTAGAAAAACCATATCTATCAATCTGCTTATTATTTTTAATTACTTCAGTTTCAAT
CACATCTTATGTTTATTCCATTCTAAAACCAAAAGACAATTCCATTTCAGAGTATTATTTATCTGAGAATGCAGATTATT
TTGTTGGTGATATTCCAGCGGATGATTCAGGTAAAATTGACTTTCAAAGAATGCACAAAGTTTATTGGTTATCAACTTCT
GGTTGGATCAATGATGAAGAATTTAAACGCATTACAGACTCAGAATACATTTGGTTAAGATCAAAGGCATTTTCCGAATT
AGAAAACGAAGAATTACATTTTTTATTAGAACATGCAGGTTTAAACATTGAAATCTTTAATGAATTTGGAGATTCCATCT
TTAAATACGGTGAATTTTCTGACCCGAAATATTTACCGAATATCTTCCAATCCAAATTTTCATGGGTTAAAATCCCGAAA
GACAAATCAGAATACTACTATTTACGTTTATTCCATAAAAAAGGTATTTTGTTTTCCATTACCATAATCGAGAATTTAAT
CGGAAAACAAACGGCATTGTATCGTGAGATAGCATTAAAAAATTTAACCACAATCTTTTTCCATTCTTTCTTTATGATGA
TTGGAATCATATGTGCTTTGGTTTATTTTATCGAATACAAAAAACAGTATAATATACTTTTAGATTTTTCTTCATTCTCA
CTTTGTTTTGGAATATTAGGCTTAACATCGAACGAATTCATTCGATACTTATTTACAAATACTCAAACCTTATACGTATT
ATCTATCATTTCATCTAATTTTGTTTTTATACCAATGTTATCTGGTGTTCGAAGATTGTTTGGAAGTGGATCTTTTCGAA
TATTAGATTTTTTAATTTATATAGATGTTTTTATTTGTTCCATAACAACCCTCTTAGTCTTTTCACTTCCTTTCTCCGAT
ATTTCACATTCATTTCTCATAAGCACTCGTAGTTTTTTTATCATCTTCAATTTATTAAATATTTTAGGTCCAATTTTTAT
CACTTATGAAGCATGGAAAAGAGGAAACAAGGAAGCTTTTGGCCATTTTATAGGATTTAGCATAACATTATTGTTAGTGA
TTTTGGAAATCTTTTTAGCCATCAAATACAATGATACATCACCTTCAGGAATCGTATTTTGGGGAGTTTTATTTGGTGTG
ATTTCTCAAGGATTTGCTCTAGAAAGAACTTTGTTTGCCGATCGCCAAAAAGCTCTCCTTTATAAAGAAGATTTATTAAA
AGCTGAAAAAACATTAAAAGAAAGCCAACTCAAAACTCTTCAAACAAAAATGAATCCTCATTATTTGTTTAATTCGTTAA
ATACTATTCACGCTCTTCATAAAATAAAACCAGAATTGATTGGCGATGCGATTATGAGCCTTGCGAATAACTATCGTTTT
ATATCAGATAGAACAGACCGCGATTGGATTCCATTTGAAGAAGAGTGGAACTTTTTAGAAGACTACTTACATCTCCAGAA
ACTTAGATTTTACGATACAATTCAAATTGATTTTAAAAAATCTGGTGATTTTTCTTCGGTCGTATTACCACCATTACTCT
TACAACCCATCATTGAAAATTCATTTAAGCATGGATTCCGAGGATCCTCAGAAGTCCAATTCCAACTCTTCATCCATGCC
AAAATGATCAAAGACTCCGTGTTCAGTTTTGTTGTATATGATAATGGCACAGGAATTCCGGATGAATTATTATCCGATAA
ACAAAAATTGATGAGTCGATCTTTAGGGAATATAAAAGAAAGATTAAAAAACTTATATTCAGAATTTCATTTTGAAATCA
CGAGAAACTATCCGGAAGGTACTAGATCAGAAATTGAAATTATCTTAACATCTAAGGTGCAGATAACTTCCTAA

Upstream 100 bases:

>100_bases
AATTAATCAAACGGGTTCGTTTTAGTCCAGGATATGTGCAAGGCCAACCCAAAAAGATGGCTCATCGCCTTCCAATCACG
TTCTCTCTCGAAGATTAAAC

Downstream 100 bases:

>100_bases
GTTCAGTAGCCAGTGCATTGGCAGAAACTCCACCTGGAAATGTTTTGATTGTATTTAGTTTTTCATCCAAAACATAAATA
AAATTTGAATGATCAATTCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 637; Mature: 636

Protein sequence:

>637_residues
MGVAISRFLEKPYLSICLLFLITSVSITSYVYSILKPKDNSISEYYLSENADYFVGDIPADDSGKIDFQRMHKVYWLSTS
GWINDEEFKRITDSEYIWLRSKAFSELENEELHFLLEHAGLNIEIFNEFGDSIFKYGEFSDPKYLPNIFQSKFSWVKIPK
DKSEYYYLRLFHKKGILFSITIIENLIGKQTALYREIALKNLTTIFFHSFFMMIGIICALVYFIEYKKQYNILLDFSSFS
LCFGILGLTSNEFIRYLFTNTQTLYVLSIISSNFVFIPMLSGVRRLFGSGSFRILDFLIYIDVFICSITTLLVFSLPFSD
ISHSFLISTRSFFIIFNLLNILGPIFITYEAWKRGNKEAFGHFIGFSITLLLVILEIFLAIKYNDTSPSGIVFWGVLFGV
ISQGFALERTLFADRQKALLYKEDLLKAEKTLKESQLKTLQTKMNPHYLFNSLNTIHALHKIKPELIGDAIMSLANNYRF
ISDRTDRDWIPFEEEWNFLEDYLHLQKLRFYDTIQIDFKKSGDFSSVVLPPLLLQPIIENSFKHGFRGSSEVQFQLFIHA
KMIKDSVFSFVVYDNGTGIPDELLSDKQKLMSRSLGNIKERLKNLYSEFHFEITRNYPEGTRSEIEIILTSKVQITS

Sequences:

>Translated_637_residues
MGVAISRFLEKPYLSICLLFLITSVSITSYVYSILKPKDNSISEYYLSENADYFVGDIPADDSGKIDFQRMHKVYWLSTS
GWINDEEFKRITDSEYIWLRSKAFSELENEELHFLLEHAGLNIEIFNEFGDSIFKYGEFSDPKYLPNIFQSKFSWVKIPK
DKSEYYYLRLFHKKGILFSITIIENLIGKQTALYREIALKNLTTIFFHSFFMMIGIICALVYFIEYKKQYNILLDFSSFS
LCFGILGLTSNEFIRYLFTNTQTLYVLSIISSNFVFIPMLSGVRRLFGSGSFRILDFLIYIDVFICSITTLLVFSLPFSD
ISHSFLISTRSFFIIFNLLNILGPIFITYEAWKRGNKEAFGHFIGFSITLLLVILEIFLAIKYNDTSPSGIVFWGVLFGV
ISQGFALERTLFADRQKALLYKEDLLKAEKTLKESQLKTLQTKMNPHYLFNSLNTIHALHKIKPELIGDAIMSLANNYRF
ISDRTDRDWIPFEEEWNFLEDYLHLQKLRFYDTIQIDFKKSGDFSSVVLPPLLLQPIIENSFKHGFRGSSEVQFQLFIHA
KMIKDSVFSFVVYDNGTGIPDELLSDKQKLMSRSLGNIKERLKNLYSEFHFEITRNYPEGTRSEIEIILTSKVQITS
>Mature_636_residues
GVAISRFLEKPYLSICLLFLITSVSITSYVYSILKPKDNSISEYYLSENADYFVGDIPADDSGKIDFQRMHKVYWLSTSG
WINDEEFKRITDSEYIWLRSKAFSELENEELHFLLEHAGLNIEIFNEFGDSIFKYGEFSDPKYLPNIFQSKFSWVKIPKD
KSEYYYLRLFHKKGILFSITIIENLIGKQTALYREIALKNLTTIFFHSFFMMIGIICALVYFIEYKKQYNILLDFSSFSL
CFGILGLTSNEFIRYLFTNTQTLYVLSIISSNFVFIPMLSGVRRLFGSGSFRILDFLIYIDVFICSITTLLVFSLPFSDI
SHSFLISTRSFFIIFNLLNILGPIFITYEAWKRGNKEAFGHFIGFSITLLLVILEIFLAIKYNDTSPSGIVFWGVLFGVI
SQGFALERTLFADRQKALLYKEDLLKAEKTLKESQLKTLQTKMNPHYLFNSLNTIHALHKIKPELIGDAIMSLANNYRFI
SDRTDRDWIPFEEEWNFLEDYLHLQKLRFYDTIQIDFKKSGDFSSVVLPPLLLQPIIENSFKHGFRGSSEVQFQLFIHAK
MIKDSVFSFVVYDNGTGIPDELLSDKQKLMSRSLGNIKERLKNLYSEFHFEITRNYPEGTRSEIEIILTSKVQITS

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3275

COG function: function code T; Putative regulator of cell autolysis

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=182, Percent_Identity=26.3736263736264, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788446, Length=132, Percent_Identity=31.8181818181818, Blast_Score=76, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 74173; Mature: 74042

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVAISRFLEKPYLSICLLFLITSVSITSYVYSILKPKDNSISEYYLSENADYFVGDIPA
CCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCEEEECCCC
DDSGKIDFQRMHKVYWLSTSGWINDEEFKRITDSEYIWLRSKAFSELENEELHFLLEHAG
CCCCCCCHHHHCEEEEEECCCCCCHHHHHHCCCCCEEEEEHHHHHHCCCHHHHHHHHHCC
LNIEIFNEFGDSIFKYGEFSDPKYLPNIFQSKFSWVKIPKDKSEYYYLRLFHKKGILFSI
CCEEEHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEEECCCCCCCEEEEEEEECCCCEEEH
TIIENLIGKQTALYREIALKNLTTIFFHSFFMMIGIICALVYFIEYKKQYNILLDFSSFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHH
LCFGILGLTSNEFIRYLFTNTQTLYVLSIISSNFVFIPMLSGVRRLFGSGSFRILDFLIY
HHHHHHCCCHHHHHHHHHCCCCCEEEEEEHHCCCEEEHHHHHHHHHHCCCCHHHHHHHHH
IDVFICSITTLLVFSLPFSDISHSFLISTRSFFIIFNLLNILGPIFITYEAWKRGNKEAF
HHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHCCCHHHH
GHFIGFSITLLLVILEIFLAIKYNDTSPSGIVFWGVLFGVISQGFALERTLFADRQKALL
HHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
YKEDLLKAEKTLKESQLKTLQTKMNPHYLFNSLNTIHALHKIKPELIGDAIMSLANNYRF
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCEE
ISDRTDRDWIPFEEEWNFLEDYLHLQKLRFYDTIQIDFKKSGDFSSVVLPPLLLQPIIEN
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCHHHHHHHHHHHHHHH
SFKHGFRGSSEVQFQLFIHAKMIKDSVFSFVVYDNGTGIPDELLSDKQKLMSRSLGNIKE
HHHCCCCCCCCEEEEEEEHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
RLKNLYSEFHFEITRNYPEGTRSEIEIILTSKVQITS
HHHHHHHHHEEHEECCCCCCCCCCEEEEEECCEEECC
>Mature Secondary Structure 
GVAISRFLEKPYLSICLLFLITSVSITSYVYSILKPKDNSISEYYLSENADYFVGDIPA
CCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCEEEECCCC
DDSGKIDFQRMHKVYWLSTSGWINDEEFKRITDSEYIWLRSKAFSELENEELHFLLEHAG
CCCCCCCHHHHCEEEEEECCCCCCHHHHHHCCCCCEEEEEHHHHHHCCCHHHHHHHHHCC
LNIEIFNEFGDSIFKYGEFSDPKYLPNIFQSKFSWVKIPKDKSEYYYLRLFHKKGILFSI
CCEEEHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEEECCCCCCCEEEEEEEECCCCEEEH
TIIENLIGKQTALYREIALKNLTTIFFHSFFMMIGIICALVYFIEYKKQYNILLDFSSFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHH
LCFGILGLTSNEFIRYLFTNTQTLYVLSIISSNFVFIPMLSGVRRLFGSGSFRILDFLIY
HHHHHHCCCHHHHHHHHHCCCCCEEEEEEHHCCCEEEHHHHHHHHHHCCCCHHHHHHHHH
IDVFICSITTLLVFSLPFSDISHSFLISTRSFFIIFNLLNILGPIFITYEAWKRGNKEAF
HHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHCCCHHHH
GHFIGFSITLLLVILEIFLAIKYNDTSPSGIVFWGVLFGVISQGFALERTLFADRQKALL
HHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
YKEDLLKAEKTLKESQLKTLQTKMNPHYLFNSLNTIHALHKIKPELIGDAIMSLANNYRF
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCEE
ISDRTDRDWIPFEEEWNFLEDYLHLQKLRFYDTIQIDFKKSGDFSSVVLPPLLLQPIIEN
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCHHHHHHHHHHHHHHH
SFKHGFRGSSEVQFQLFIHAKMIKDSVFSFVVYDNGTGIPDELLSDKQKLMSRSLGNIKE
HHHCCCCCCCCEEEEEEEHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
RLKNLYSEFHFEITRNYPEGTRSEIEIILTSKVQITS
HHHHHHHHHEEHEECCCCCCCCCCEEEEEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12663927 [H]