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The map label for this gene is tagA [H]

Identifier: 183222311

GI number: 183222311

Start: 3065383

End: 3066195

Strand: Direct

Name: tagA [H]

Synonym: LEPBI_I2963

Alternate gene names: 183222311

Gene position: 3065383-3066195 (Clockwise)

Preceding gene: 183222307

Following gene: 183222313

Centisome position: 85.16

GC content: 44.53

Gene sequence:

>813_bases
ATGAAGCAATTGAGCGAAATCGTTCACAATTCCTCAAAAGACGAGAGAGATATACTACTCGAATACCAGAATATCGATGT
TTCTAAGTTGGAAACCTTAAACGTTCTGGGAATTCCAATAGACAATGTCACAACTGATGAAGCCATTGCCAAACTCTTCC
GCGTGCTTGAGAAAAAAGAAGGCATGCACCACGTACTGTTTTTAGATCCGATCAAACTCATGAGGATGCGCCCGAAAAAA
GCCCTCCACCGCATTGCGGAAAAAGCAGGTACCATTTTAGTGGAAGGTGCCGGGATCGGGTGGATGACAAAGGGACGATT
GAAGGAACGAGTGACCCCAATCGCTGTGATGATGGACCTCATCCGCCTTGCAGAACTCAAAGAATTTACGGCATTTATTT
TTGGTGCCAAAGACGAAATCGTAGAACGAATTTATTTTAACCTCACAAGGCATTTTCCAAAGGTTCGCATTGTGGGAAGG
CATGCTGGCCATCTTGATAGACAACGTGAAATGCGAGTCAAAGAAGCCATCCGTAAAACAGGACCCGATATCATCTTCCT
TGCCATGGACTTCCCTGAACAAGAAATTTGGATCGAAAATAACACTGGTTACTTTGGCAAAGCAGTTGTCATCGGTGTCG
GCGGCGCCTTAGATATGTTATCTGGTGCTGACAAAAAAGCGCCTGAATGGTTCAAAGAAAGAGGTCTTATCTGGTTATGG
CGAATCATCGCAAGACCTTATCGTATCCGAAGGATGGGGGAAACTTTTTACTTCATCCTACTCGGAATCCGCGAACGATT
CCGCAAACATTAA

Upstream 100 bases:

>100_bases
GTTCCAATCCAAGTGAAAAAACGAAAGTTTTTAAAAATTTAGAGGCGACAAGAGAGGTACTGGACATAATGCTTAAGTTA
GGAAAGGAAAACCTGGCTAC

Downstream 100 bases:

>100_bases
ACTCTATTTTTTAATCTGATCCAAACGATCGAGGGTTGGTGCGAGCCAATCTTCGAGTAGTGGTTCTCTATCAAGTTTTG
CACGTGCAAACACCAAATCT

Product: putative glycosyl transferase

Products: NA

Alternate protein names: Major teichoic acid biosynthesis protein A; N-acetylglucosaminyldiphospho-undecaprenol N-acetyl-beta-D-mannosaminyltransferase; UDP-N-acetylmannosamine transferase [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MKQLSEIVHNSSKDERDILLEYQNIDVSKLETLNVLGIPIDNVTTDEAIAKLFRVLEKKEGMHHVLFLDPIKLMRMRPKK
ALHRIAEKAGTILVEGAGIGWMTKGRLKERVTPIAVMMDLIRLAELKEFTAFIFGAKDEIVERIYFNLTRHFPKVRIVGR
HAGHLDRQREMRVKEAIRKTGPDIIFLAMDFPEQEIWIENNTGYFGKAVVIGVGGALDMLSGADKKAPEWFKERGLIWLW
RIIARPYRIRRMGETFYFILLGIRERFRKH

Sequences:

>Translated_270_residues
MKQLSEIVHNSSKDERDILLEYQNIDVSKLETLNVLGIPIDNVTTDEAIAKLFRVLEKKEGMHHVLFLDPIKLMRMRPKK
ALHRIAEKAGTILVEGAGIGWMTKGRLKERVTPIAVMMDLIRLAELKEFTAFIFGAKDEIVERIYFNLTRHFPKVRIVGR
HAGHLDRQREMRVKEAIRKTGPDIIFLAMDFPEQEIWIENNTGYFGKAVVIGVGGALDMLSGADKKAPEWFKERGLIWLW
RIIARPYRIRRMGETFYFILLGIRERFRKH
>Mature_270_residues
MKQLSEIVHNSSKDERDILLEYQNIDVSKLETLNVLGIPIDNVTTDEAIAKLFRVLEKKEGMHHVLFLDPIKLMRMRPKK
ALHRIAEKAGTILVEGAGIGWMTKGRLKERVTPIAVMMDLIRLAELKEFTAFIFGAKDEIVERIYFNLTRHFPKVRIVGR
HAGHLDRQREMRVKEAIRKTGPDIIFLAMDFPEQEIWIENNTGYFGKAVVIGVGGALDMLSGADKKAPEWFKERGLIWLW
RIIARPYRIRRMGETFYFILLGIRERFRKH

Specific function: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, a key lipid intermediate in the de novo synthesis of teichoic acid (Potential) [H]

COG id: COG1922

COG function: function code M; Teichoic acid biosynthesis proteins

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 26 family [H]

Homologues:

Organism=Escherichia coli, GI2367289, Length=119, Percent_Identity=31.9327731092437, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004629 [H]

Pfam domain/function: PF03808 Glyco_tran_WecB [H]

EC number: =2.4.1.187 [H]

Molecular weight: Translated: 31407; Mature: 31407

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLSEIVHNSSKDERDILLEYQNIDVSKLETLNVLGIPIDNVTTDEAIAKLFRVLEKKE
CCHHHHHHHCCCCCCHHEEEEECCCCHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHC
GMHHVLFLDPIKLMRMRPKKALHRIAEKAGTILVEGAGIGWMTKGRLKERVTPIAVMMDL
CCEEEEEECHHHHHHCCHHHHHHHHHHHHCEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
IRLAELKEFTAFIFGAKDEIVERIYFNLTRHFPKVRIVGRHAGHLDRQREMRVKEAIRKT
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHC
GPDIIFLAMDFPEQEIWIENNTGYFGKAVVIGVGGALDMLSGADKKAPEWFKERGLIWLW
CCCEEEEEECCCCCEEEEECCCCCCCCEEEEECCCHHHHHCCCCCCCHHHHHHCCHHHHH
RIIARPYRIRRMGETFYFILLGIRERFRKH
HHHHCCHHHHHHCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKQLSEIVHNSSKDERDILLEYQNIDVSKLETLNVLGIPIDNVTTDEAIAKLFRVLEKKE
CCHHHHHHHCCCCCCHHEEEEECCCCHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHC
GMHHVLFLDPIKLMRMRPKKALHRIAEKAGTILVEGAGIGWMTKGRLKERVTPIAVMMDL
CCEEEEEECHHHHHHCCHHHHHHHHHHHHCEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
IRLAELKEFTAFIFGAKDEIVERIYFNLTRHFPKVRIVGRHAGHLDRQREMRVKEAIRKT
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHC
GPDIIFLAMDFPEQEIWIENNTGYFGKAVVIGVGGALDMLSGADKKAPEWFKERGLIWLW
CCCEEEEEECCCCCEEEEECCCCCCCCEEEEECCCHHHHHCCCCCCCHHHHHHCCHHHHH
RIIARPYRIRRMGETFYFILLGIRERFRKH
HHHHCCHHHHHHCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1906926; 9384377; 11882717 [H]