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The map label for this gene is cobT [H]

Identifier: 183222286

GI number: 183222286

Start: 3037063

End: 3038127

Strand: Direct

Name: cobT [H]

Synonym: LEPBI_I2938

Alternate gene names: 183222286

Gene position: 3037063-3038127 (Clockwise)

Preceding gene: 183222282

Following gene: 183222287

Centisome position: 84.37

GC content: 39.91

Gene sequence:

>1065_bases
TTGTCCATGTCCCCATTTTCCCTACCCAAAATTTCCCCCGTAACCCATGTTTTGCGAGACAAAATTCGAGAAAAAATTGA
CACCAAAACAAAACCTTTAGGTTCCCTTGGTGCACTCGAATCAGTAGCACAACAAATCGCCGAAATCCAAAATACAACTT
CGCCTTCTTTACGGAATCCGAAACTAATTTTGTTTGCCGCAGACCATGGGATCACCGAAGAACCAGTCTCTCTTTACCCA
AAAGATGTAACATGGCAGATGGTGTTTAATTTTTTACATGGTGGTGCCTGTGCCAATGTATTTGCCAAACACAGTGGAAT
CGAAGTTGAAGTAGTGGATGCAGGTGTGGATCATGATTGGGATAAATCCACAATACAACTACTCCAAAAAAAAATCAGAA
AAGGTACATCTAACTTTCTTAAAACTCCTGCAATGACAAAAGAGGAAGCATATCTTTCTCTGCAAAATGGAATCCATTTA
ATAATGGATGATCGGTACAAAGACACCAATGTATTTTTATTCGGAGAAATGGGAATTGGCAATACCTCATCCGCATCCAT
GGTATTATCTCATCTAACAGGAATTCCACTCTCTAAATTGGTAGGAAAAGGAACTGGATTAAATCCCAAAGGAAAAGAAA
CAAAATTAGAAATATTGGAAAGGGCCTACCTAAGAACAGGAAAACTGAATGATCCTCTAGAAATCCTTTCTGAATTTGGC
GGATTTGAAATAGGGATGATGGCTGGAGCGATGCTCGGGGCCGCATCCAATCAAAAAGTTTTCCTTGTGGATGGATTCAT
CACTACCGCAGCATTTTTTGTCGCCTATCATCTGAATCCACTCGTAAAAGATTATGCTATTTTTTCACATGTTTCTGATG
AAGAAGGCCACATCATTGTTTTGGATCATTTTCAAATCAGACCACTTTTAAAACTAAACTTACGATTAGGAGAAGGAAGT
GGTGCGCTTGCCGCCTACCCTCTCATCGAACTCAGTGTAAAATTTTTGAATGAAATGGCTTCCTTTGCCGACGCAGGTGT
CAGCGACTCAGAGACAAAATCTTAA

Upstream 100 bases:

>100_bases
TTTTCGATTTTTTTAGGCCCAAATTGCCAAATCCCAAACCTGCCAAATCCATCCAAGCCCAAAAACGATGGATGAAGAGA
GAGCCTCAGGCAAACTGGTT

Downstream 100 bases:

>100_bases
TTCACTATGAAATATATCCTATTAGAAATCCGTTTGTTTTTTGTTTGTATGTCCTTTCTCACAAGGATTCCTTCTCCGCG
TTGGATCGGTTTTCAAGAAG

Product: nicotinate-nucleotide--dimethylbenzimidazole phophoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MSMSPFSLPKISPVTHVLRDKIREKIDTKTKPLGSLGALESVAQQIAEIQNTTSPSLRNPKLILFAADHGITEEPVSLYP
KDVTWQMVFNFLHGGACANVFAKHSGIEVEVVDAGVDHDWDKSTIQLLQKKIRKGTSNFLKTPAMTKEEAYLSLQNGIHL
IMDDRYKDTNVFLFGEMGIGNTSSASMVLSHLTGIPLSKLVGKGTGLNPKGKETKLEILERAYLRTGKLNDPLEILSEFG
GFEIGMMAGAMLGAASNQKVFLVDGFITTAAFFVAYHLNPLVKDYAIFSHVSDEEGHIIVLDHFQIRPLLKLNLRLGEGS
GALAAYPLIELSVKFLNEMASFADAGVSDSETKS

Sequences:

>Translated_354_residues
MSMSPFSLPKISPVTHVLRDKIREKIDTKTKPLGSLGALESVAQQIAEIQNTTSPSLRNPKLILFAADHGITEEPVSLYP
KDVTWQMVFNFLHGGACANVFAKHSGIEVEVVDAGVDHDWDKSTIQLLQKKIRKGTSNFLKTPAMTKEEAYLSLQNGIHL
IMDDRYKDTNVFLFGEMGIGNTSSASMVLSHLTGIPLSKLVGKGTGLNPKGKETKLEILERAYLRTGKLNDPLEILSEFG
GFEIGMMAGAMLGAASNQKVFLVDGFITTAAFFVAYHLNPLVKDYAIFSHVSDEEGHIIVLDHFQIRPLLKLNLRLGEGS
GALAAYPLIELSVKFLNEMASFADAGVSDSETKS
>Mature_353_residues
SMSPFSLPKISPVTHVLRDKIREKIDTKTKPLGSLGALESVAQQIAEIQNTTSPSLRNPKLILFAADHGITEEPVSLYPK
DVTWQMVFNFLHGGACANVFAKHSGIEVEVVDAGVDHDWDKSTIQLLQKKIRKGTSNFLKTPAMTKEEAYLSLQNGIHLI
MDDRYKDTNVFLFGEMGIGNTSSASMVLSHLTGIPLSKLVGKGTGLNPKGKETKLEILERAYLRTGKLNDPLEILSEFGG
FEIGMMAGAMLGAASNQKVFLVDGFITTAAFFVAYHLNPLVKDYAIFSHVSDEEGHIIVLDHFQIRPLLKLNLRLGEGSG
ALAAYPLIELSVKFLNEMASFADAGVSDSETKS

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=329, Percent_Identity=33.7386018237082, Blast_Score=189, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 38665; Mature: 38534

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMSPFSLPKISPVTHVLRDKIREKIDTKTKPLGSLGALESVAQQIAEIQNTTSPSLRNP
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
KLILFAADHGITEEPVSLYPKDVTWQMVFNFLHGGACANVFAKHSGIEVEVVDAGVDHDW
EEEEEECCCCCCCCCHHCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEECCCCCCC
DKSTIQLLQKKIRKGTSNFLKTPAMTKEEAYLSLQNGIHLIMDDRYKDTNVFLFGEMGIG
CHHHHHHHHHHHHHCHHHHHCCCCCCHHHHHEECCCCEEEEEECCCCCCCEEEEEECCCC
NTSSASMVLSHLTGIPLSKLVGKGTGLNPKGKETKLEILERAYLRTGKLNDPLEILSEFG
CCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHC
GFEIGMMAGAMLGAASNQKVFLVDGFITTAAFFVAYHLNPLVKDYAIFSHVSDEEGHIIV
CCCHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCEEE
LDHFQIRPLLKLNLRLGEGSGALAAYPLIELSVKFLNEMASFADAGVSDSETKS
EECCCCCEEEEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SMSPFSLPKISPVTHVLRDKIREKIDTKTKPLGSLGALESVAQQIAEIQNTTSPSLRNP
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
KLILFAADHGITEEPVSLYPKDVTWQMVFNFLHGGACANVFAKHSGIEVEVVDAGVDHDW
EEEEEECCCCCCCCCHHCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEECCCCCCC
DKSTIQLLQKKIRKGTSNFLKTPAMTKEEAYLSLQNGIHLIMDDRYKDTNVFLFGEMGIG
CHHHHHHHHHHHHHCHHHHHCCCCCCHHHHHEECCCCEEEEEECCCCCCCEEEEEECCCC
NTSSASMVLSHLTGIPLSKLVGKGTGLNPKGKETKLEILERAYLRTGKLNDPLEILSEFG
CCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHC
GFEIGMMAGAMLGAASNQKVFLVDGFITTAAFFVAYHLNPLVKDYAIFSHVSDEEGHIIV
CCCHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCEEE
LDHFQIRPLLKLNLRLGEGSGALAAYPLIELSVKFLNEMASFADAGVSDSETKS
EECCCCCEEEEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA