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The map label for this gene is trmB [H]

Identifier: 183222245

GI number: 183222245

Start: 2986430

End: 2987095

Strand: Direct

Name: trmB [H]

Synonym: LEPBI_I2896

Alternate gene names: 183222245

Gene position: 2986430-2987095 (Clockwise)

Preceding gene: 183222243

Following gene: 183222250

Centisome position: 82.96

GC content: 37.54

Gene sequence:

>666_bases
ATGCAATTGTTAGTTAATCCAGAAATCCAAGAAAAACTTTGGAAGTTTACTACCAAAACTTCCTATCAATCAGACTATCT
CCTGCAACCTAACGAACGTGGGAAAAAAATCGATCTAAAAAAATCTTTCCCATCAACAACCACTCAGTTTGTTTTAGAGC
TTGGCTCGGGTTGGGGTGAAGTTGCCATTGAATTGGCAAAAAATGACCACCAAACAGGTTACCTACTGATGGAAAAAAAG
GTAAACCGAATCATCCACACAGAAAAACAAAGGAAAACACTCGGATTAGAGAATATTCGTTATATGACAGTTAACTTCCA
ATGGTTTTTCGATGAGTTACTCGAGAAAGAAATTTTTGACAAAATCATCATCAACTTTCCCGATCCATGGCCCAAAAAAA
AACACCGCAAGAATCGACTCATGCAGCCCTATATGTTACAACAGATATACACATTGCTAAAACCAGGTGGTGAACTTTTT
TTTGCGACTGACTACGGCCCGTATGCGAGAAAAACCATCTCCTTGTTTCGAAAATTCCCAAACTTTCAATGGAAGGAGAA
GGAATATGAATTCGAAAGGCCTAATTTCCCGATTTCTTTCTTCGAGGCCGAAAAAAGAAACGAAGGGAAAACAATTTATT
ATCTAAAACGAATCAAAGCAATTTGA

Upstream 100 bases:

>100_bases
CCTGTTTTGATATCGGTGTAGGAAGGGAACCTCGTACACCAAAAAGAGTTATTTTCATCTAGTTCCTTTTTAAAATCCTG
ACATTAAATCATCGGAAGAA

Downstream 100 bases:

>100_bases
ACTGACAGTTGTGTTAGAGTCCACTGCTCCCGTAACCTCATGTGAACGGGAGATCCAATCGATCGATTGTTAGTCCACTG
TAATCGTACTGATCCTAAGT

Product: tRNA (guanine-N(7)-)-methyltransferase

Products: NA

Alternate protein names: tRNA(m7G46)-methyltransferase [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MQLLVNPEIQEKLWKFTTKTSYQSDYLLQPNERGKKIDLKKSFPSTTTQFVLELGSGWGEVAIELAKNDHQTGYLLMEKK
VNRIIHTEKQRKTLGLENIRYMTVNFQWFFDELLEKEIFDKIIINFPDPWPKKKHRKNRLMQPYMLQQIYTLLKPGGELF
FATDYGPYARKTISLFRKFPNFQWKEKEYEFERPNFPISFFEAEKRNEGKTIYYLKRIKAI

Sequences:

>Translated_221_residues
MQLLVNPEIQEKLWKFTTKTSYQSDYLLQPNERGKKIDLKKSFPSTTTQFVLELGSGWGEVAIELAKNDHQTGYLLMEKK
VNRIIHTEKQRKTLGLENIRYMTVNFQWFFDELLEKEIFDKIIINFPDPWPKKKHRKNRLMQPYMLQQIYTLLKPGGELF
FATDYGPYARKTISLFRKFPNFQWKEKEYEFERPNFPISFFEAEKRNEGKTIYYLKRIKAI
>Mature_221_residues
MQLLVNPEIQEKLWKFTTKTSYQSDYLLQPNERGKKIDLKKSFPSTTTQFVLELGSGWGEVAIELAKNDHQTGYLLMEKK
VNRIIHTEKQRKTLGLENIRYMTVNFQWFFDELLEKEIFDKIIINFPDPWPKKKHRKNRLMQPYMLQQIYTLLKPGGELF
FATDYGPYARKTISLFRKFPNFQWKEKEYEFERPNFPISFFEAEKRNEGKTIYYLKRIKAI

Specific function: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA [H]

COG id: COG0220

COG function: function code R; Predicted S-adenosylmethionine-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. TrmB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003358 [H]

Pfam domain/function: PF02390 Methyltransf_4 [H]

EC number: =2.1.1.33 [H]

Molecular weight: Translated: 26656; Mature: 26656

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLLVNPEIQEKLWKFTTKTSYQSDYLLQPNERGKKIDLKKSFPSTTTQFVLELGSGWGE
CCEEECCHHHHHHHHHHHCCCCCCCCEECCCCCCCEEEECCCCCCHHHHHHHHHCCCCCC
VAIELAKNDHQTGYLLMEKKVNRIIHTEKQRKTLGLENIRYMTVNFQWFFDELLEKEIFD
EEEEEECCCCCCCEEEHHHHHHHHHHCHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHH
KIIINFPDPWPKKKHRKNRLMQPYMLQQIYTLLKPGGELFFATDYGPYARKTISLFRKFP
HHEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCC
NFQWKEKEYEFERPNFPISFFEAEKRNEGKTIYYLKRIKAI
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEHHHCC
>Mature Secondary Structure
MQLLVNPEIQEKLWKFTTKTSYQSDYLLQPNERGKKIDLKKSFPSTTTQFVLELGSGWGE
CCEEECCHHHHHHHHHHHCCCCCCCCEECCCCCCCEEEECCCCCCHHHHHHHHHCCCCCC
VAIELAKNDHQTGYLLMEKKVNRIIHTEKQRKTLGLENIRYMTVNFQWFFDELLEKEIFD
EEEEEECCCCCCCEEEHHHHHHHHHHCHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHH
KIIINFPDPWPKKKHRKNRLMQPYMLQQIYTLLKPGGELFFATDYGPYARKTISLFRKFP
HHEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCC
NFQWKEKEYEFERPNFPISFFEAEKRNEGKTIYYLKRIKAI
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA