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The map label for this gene is mcpC [H]

Identifier: 183222204

GI number: 183222204

Start: 2943820

End: 2945793

Strand: Direct

Name: mcpC [H]

Synonym: LEPBI_I2854

Alternate gene names: 183222204

Gene position: 2943820-2945793 (Clockwise)

Preceding gene: 183222202

Following gene: 183222205

Centisome position: 81.78

GC content: 33.08

Gene sequence:

>1974_bases
ATGCGTGTGTTTGATCTAAGTATTCTTTCAAAAATATCCATTCAAAGTAGATTGTTATTATTCCCTTTACCACTTCTTAT
TTCGCTATTTTTTATCCTATTTTTACTCGTAACCTCGCAAAACGAATCAATCCAATTCTCCAACAAGGAACAATTGGGTC
TCGAATTGACGAAACCTATTTCTGCATCCTATCGAAAGGGATTAGAGCGCTTGAAAATCGGCCAAGAATCAACAGTGGAA
TTATTGCCGGTAATGGAGGAAATTAAAAAAGAAATTCTCAAGTCAAGTATCATCGACCCTAAATCAAAAGAGTTTACCAA
TATAGAGAGATATAACAAGTTCAAAGAATTTGATCAAACAACTACCCTTCTATTCCTAAATGATCTACAGGAATTGTTAT
TAAAAGTAGGAGATAATTCAAATTTAATTCTTGATCCAGAAGTAGATTCTTACTACCAAATGGAAATTGTTTTATTCAGA
ATTCCAACGATCTACCAAAATATCGCAGTTCTAAAAGAAGTGATTCGAGACGAATATTTGGGAACAATTGCAAACAATAA
AACAATTACGAATGCAAGCATAACAAAAGTAATCATAACAATCAATGGAATTGAAAATGCTTGTAAAGAAATTCGTAAAT
CATACAAAAAATCAAGTGATTCCAATCAGAAATACCAAAAAGAAATCGACGTAGCAGTACACTATGCAAATGCCAACTGT
GATGAATATATAAAAGAGCTCAAAGATACTTTTATTAAAAGTCAAATTAAACCAAACAATTCCGATTCACTTTTTCTCAC
GATACACAAAGGGACAAAAATTGCAGGCAATATACAAGAAAATTCACAAACATTATTAGCGAATATGATCACAGATCGAG
TAGAATTACTATCAATCAAAAGAAATTTCAACATTTTATTGGTTCTAATTTCACTTCTTATATCAACAATTTTTGTATAT
CTCATCTTTAGAAGCATCAATAAACCACTAGTGACTGTACTCACAAAGATCAATGAGCTATCAAGCGGTGAGGCAGACCT
TTCAAAAACATTACCAGATTTTGGAACGAATGAAATTGGCAAAATCACAAAATCAATCAATCAATTTTTAGACAACCTAA
ATCATATCATGAACCAACTAAAGGCCTCTGTTAGCGAGTCTGAAAAATTATCGAGTCAATTAAAACAAGATGCAATCTCT
GTTTCGGACAATGCTTCATCACTTGCTTCCGTATCCGAAGAATCTGCAGCTTCATTAGAAGAACTCACAACCTCTTTTGA
AATTATGTTCGAATTCATAACAAATGAAACAAAAAACATAGTCAATATCACAGAAGAGATGGCAAACATCAAATCCTCAA
TTCAAAATATTGAATTCGCTTTACATCAGTTAACTGACTTATCAAATTATTCTACAAAACTTGCCAATTCTGGAAATTTA
TCCATCAAGAATACTGACACTACGATGTCAGAAATAAGATCTGTGACCAAGGAAATTACGGGAATTATTGATTTAATCAC
TGAAATTTCAGAAAGAACCAATTTGCTTGCATTAAACGCAAGTATAGAAGCAGCAAGAGCAGGTGATGCAGGAATGGGGT
TTGCAGTGGTTGCAGAAGAAATATCTAAACTCGCGGACAAAACTCAATCATCTGTTAAAAGCATAAAAAAATTGATCGAT
AAAAGCCATGTTGTTGTTAATGAAGGTTCAAGTCATGTGATGGAAGCAGTGAACGCACTTAGCGAAATTGTAACACAATC
CAAAAGAATGAATGATGCGGTGAACCATTTAAAAGAAGAAATGACTACTCAATCAAACAGTTTACTCAGCGTAACCAATG
AACTCAATGGACTCGAAGACATGGCTAAAACCATTGAATTCTCAAGCAGAGAACAAAAAAAAGCATCAGAAGATATGGTC
AATACTGTAAATATATTATCGGGAAGCGCCCAAGAACTTGCAAATAATTCCTAA

Upstream 100 bases:

>100_bases
GATTCTCCGTAGTTCCTCTAGGAAATAAAATGAGCGAAATTTTGAAAATCAATTATCGCCTCGATAATATTTTGAAAATT
AATTCGTCATCTTTCGTAAG

Downstream 100 bases:

>100_bases
GACTTAATCCAAGTGAGCCAAAAAATCGGAGATATCGCAACTAACATTGCGGTAATCACAAACACATTTCATACACATTA
ATCAATAAAATAATCAAATA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 657; Mature: 657

Protein sequence:

>657_residues
MRVFDLSILSKISIQSRLLLFPLPLLISLFFILFLLVTSQNESIQFSNKEQLGLELTKPISASYRKGLERLKIGQESTVE
LLPVMEEIKKEILKSSIIDPKSKEFTNIERYNKFKEFDQTTTLLFLNDLQELLLKVGDNSNLILDPEVDSYYQMEIVLFR
IPTIYQNIAVLKEVIRDEYLGTIANNKTITNASITKVIITINGIENACKEIRKSYKKSSDSNQKYQKEIDVAVHYANANC
DEYIKELKDTFIKSQIKPNNSDSLFLTIHKGTKIAGNIQENSQTLLANMITDRVELLSIKRNFNILLVLISLLISTIFVY
LIFRSINKPLVTVLTKINELSSGEADLSKTLPDFGTNEIGKITKSINQFLDNLNHIMNQLKASVSESEKLSSQLKQDAIS
VSDNASSLASVSEESAASLEELTTSFEIMFEFITNETKNIVNITEEMANIKSSIQNIEFALHQLTDLSNYSTKLANSGNL
SIKNTDTTMSEIRSVTKEITGIIDLITEISERTNLLALNASIEAARAGDAGMGFAVVAEEISKLADKTQSSVKSIKKLID
KSHVVVNEGSSHVMEAVNALSEIVTQSKRMNDAVNHLKEEMTTQSNSLLSVTNELNGLEDMAKTIEFSSREQKKASEDMV
NTVNILSGSAQELANNS

Sequences:

>Translated_657_residues
MRVFDLSILSKISIQSRLLLFPLPLLISLFFILFLLVTSQNESIQFSNKEQLGLELTKPISASYRKGLERLKIGQESTVE
LLPVMEEIKKEILKSSIIDPKSKEFTNIERYNKFKEFDQTTTLLFLNDLQELLLKVGDNSNLILDPEVDSYYQMEIVLFR
IPTIYQNIAVLKEVIRDEYLGTIANNKTITNASITKVIITINGIENACKEIRKSYKKSSDSNQKYQKEIDVAVHYANANC
DEYIKELKDTFIKSQIKPNNSDSLFLTIHKGTKIAGNIQENSQTLLANMITDRVELLSIKRNFNILLVLISLLISTIFVY
LIFRSINKPLVTVLTKINELSSGEADLSKTLPDFGTNEIGKITKSINQFLDNLNHIMNQLKASVSESEKLSSQLKQDAIS
VSDNASSLASVSEESAASLEELTTSFEIMFEFITNETKNIVNITEEMANIKSSIQNIEFALHQLTDLSNYSTKLANSGNL
SIKNTDTTMSEIRSVTKEITGIIDLITEISERTNLLALNASIEAARAGDAGMGFAVVAEEISKLADKTQSSVKSIKKLID
KSHVVVNEGSSHVMEAVNALSEIVTQSKRMNDAVNHLKEEMTTQSNSLLSVTNELNGLEDMAKTIEFSSREQKKASEDMV
NTVNILSGSAQELANNS
>Mature_657_residues
MRVFDLSILSKISIQSRLLLFPLPLLISLFFILFLLVTSQNESIQFSNKEQLGLELTKPISASYRKGLERLKIGQESTVE
LLPVMEEIKKEILKSSIIDPKSKEFTNIERYNKFKEFDQTTTLLFLNDLQELLLKVGDNSNLILDPEVDSYYQMEIVLFR
IPTIYQNIAVLKEVIRDEYLGTIANNKTITNASITKVIITINGIENACKEIRKSYKKSSDSNQKYQKEIDVAVHYANANC
DEYIKELKDTFIKSQIKPNNSDSLFLTIHKGTKIAGNIQENSQTLLANMITDRVELLSIKRNFNILLVLISLLISTIFVY
LIFRSINKPLVTVLTKINELSSGEADLSKTLPDFGTNEIGKITKSINQFLDNLNHIMNQLKASVSESEKLSSQLKQDAIS
VSDNASSLASVSEESAASLEELTTSFEIMFEFITNETKNIVNITEEMANIKSSIQNIEFALHQLTDLSNYSTKLANSGNL
SIKNTDTTMSEIRSVTKEITGIIDLITEISERTNLLALNASIEAARAGDAGMGFAVVAEEISKLADKTQSSVKSIKKLID
KSHVVVNEGSSHVMEAVNALSEIVTQSKRMNDAVNHLKEEMTTQSNSLLSVTNELNGLEDMAKTIEFSSREQKKASEDMV
NTVNILSGSAQELANNS

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=354, Percent_Identity=27.1186440677966, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI2367378, Length=305, Percent_Identity=28.8524590163934, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1787690, Length=324, Percent_Identity=27.7777777777778, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1788195, Length=289, Percent_Identity=29.4117647058824, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1789453, Length=315, Percent_Identity=28.5714285714286, Blast_Score=98, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 73323; Mature: 73323

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVFDLSILSKISIQSRLLLFPLPLLISLFFILFLLVTSQNESIQFSNKEQLGLELTKPI
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHCCCCCCCCC
SASYRKGLERLKIGQESTVELLPVMEEIKKEILKSSIIDPKSKEFTNIERYNKFKEFDQT
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
TTLLFLNDLQELLLKVGDNSNLILDPEVDSYYQMEIVLFRIPTIYQNIAVLKEVIRDEYL
HHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEEHEEEEEEHHHHHHHHHHHHHHHHHHHH
GTIANNKTITNASITKVIITINGIENACKEIRKSYKKSSDSNQKYQKEIDVAVHYANANC
HHHCCCCEECCCEEEEEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHEEEECCCCH
DEYIKELKDTFIKSQIKPNNSDSLFLTIHKGTKIAGNIQENSQTLLANMITDRVELLSIK
HHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHH
RNFNILLVLISLLISTIFVYLIFRSINKPLVTVLTKINELSSGEADLSKTLPDFGTNEIG
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHH
KITKSINQFLDNLNHIMNQLKASVSESEKLSSQLKQDAISVSDNASSLASVSEESAASLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ELTTSFEIMFEFITNETKNIVNITEEMANIKSSIQNIEFALHQLTDLSNYSTKLANSGNL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
SIKNTDTTMSEIRSVTKEITGIIDLITEISERTNLLALNASIEAARAGDAGMGFAVVAEE
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHCCCCCCCHHHHHHHH
ISKLADKTQSSVKSIKKLIDKSHVVVNEGSSHVMEAVNALSEIVTQSKRMNDAVNHLKEE
HHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTTQSNSLLSVTNELNGLEDMAKTIEFSSREQKKASEDMVNTVNILSGSAQELANNS
HHHCCCCHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCC
>Mature Secondary Structure
MRVFDLSILSKISIQSRLLLFPLPLLISLFFILFLLVTSQNESIQFSNKEQLGLELTKPI
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHCCCCCCCCC
SASYRKGLERLKIGQESTVELLPVMEEIKKEILKSSIIDPKSKEFTNIERYNKFKEFDQT
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
TTLLFLNDLQELLLKVGDNSNLILDPEVDSYYQMEIVLFRIPTIYQNIAVLKEVIRDEYL
HHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEEHEEEEEEHHHHHHHHHHHHHHHHHHHH
GTIANNKTITNASITKVIITINGIENACKEIRKSYKKSSDSNQKYQKEIDVAVHYANANC
HHHCCCCEECCCEEEEEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHEEEECCCCH
DEYIKELKDTFIKSQIKPNNSDSLFLTIHKGTKIAGNIQENSQTLLANMITDRVELLSIK
HHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHH
RNFNILLVLISLLISTIFVYLIFRSINKPLVTVLTKINELSSGEADLSKTLPDFGTNEIG
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHH
KITKSINQFLDNLNHIMNQLKASVSESEKLSSQLKQDAISVSDNASSLASVSEESAASLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ELTTSFEIMFEFITNETKNIVNITEEMANIKSSIQNIEFALHQLTDLSNYSTKLANSGNL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
SIKNTDTTMSEIRSVTKEITGIIDLITEISERTNLLALNASIEAARAGDAGMGFAVVAEE
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHCCCCCCCHHHHHHHH
ISKLADKTQSSVKSIKKLIDKSHVVVNEGSSHVMEAVNALSEIVTQSKRMNDAVNHLKEE
HHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTTQSNSLLSVTNELNGLEDMAKTIEFSSREQKKASEDMVNTVNILSGSAQELANNS
HHHCCCCHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353924; 9384377 [H]