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The map label for this gene is 183222197

Identifier: 183222197

GI number: 183222197

Start: 2938489

End: 2938902

Strand: Direct

Name: 183222197

Synonym: LEPBI_I2847

Alternate gene names: NA

Gene position: 2938489-2938902 (Clockwise)

Preceding gene: 183222195

Following gene: 183222198

Centisome position: 81.63

GC content: 37.44

Gene sequence:

>414_bases
ATGTCCACAAAAGATACGACTTTCGTTTATTGTGATGGAAGCTCCAGAGGGAATCCTGGACCCGCTGCAATCGGTGTTTC
CTTTCAAAACAATGAAGGAATGGAATTTCATTTCCTTTCAGAAAAAATAGGGAACGCAACCAATAATGTCGCTGAATGGA
ACGCACTATCTCGTGGAATGGAAGAAGCGATTAGGCAAAGCATAAAAAAGATTAAGTTTCGATTGGACTCAGAACTTGTC
GTCAAACAAATGAAAGGTGAATATAAAGTAAAAAATAAAGATCTAATGGTATTTAAAACGAAGTGTGACCAACTTAAAAA
TTCATTTGAGAGCTTTGATATTCAATACATTCCGCGCGAACAAAATGCACGAGCCGATCAACTTGCTAATTTTGCTCAAG
ATTCCAAACCATGA

Upstream 100 bases:

>100_bases
AAAAAAAGTCCTCCCTAATTCCAGTTCTTCGATTTTTTTTTCTAATTGGTTCGTGTTTTTGATTGGTGAGGAGGGTCTCC
AGAAAAACAATGTCGGCTAT

Downstream 100 bases:

>100_bases
TAAGATTCACACATCATCAGATTCTTGGCTTGGCATTCATTCTGATTCAATTAGGTTGTAAATTATCACCCGCTAAACAA
TTGGATCGATTATTGGAAGA

Product: putative ribonuclease H

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 137; Mature: 136

Protein sequence:

>137_residues
MSTKDTTFVYCDGSSRGNPGPAAIGVSFQNNEGMEFHFLSEKIGNATNNVAEWNALSRGMEEAIRQSIKKIKFRLDSELV
VKQMKGEYKVKNKDLMVFKTKCDQLKNSFESFDIQYIPREQNARADQLANFAQDSKP

Sequences:

>Translated_137_residues
MSTKDTTFVYCDGSSRGNPGPAAIGVSFQNNEGMEFHFLSEKIGNATNNVAEWNALSRGMEEAIRQSIKKIKFRLDSELV
VKQMKGEYKVKNKDLMVFKTKCDQLKNSFESFDIQYIPREQNARADQLANFAQDSKP
>Mature_136_residues
STKDTTFVYCDGSSRGNPGPAAIGVSFQNNEGMEFHFLSEKIGNATNNVAEWNALSRGMEEAIRQSIKKIKFRLDSELVV
KQMKGEYKVKNKDLMVFKTKCDQLKNSFESFDIQYIPREQNARADQLANFAQDSKP

Specific function: Unknown

COG id: COG0328

COG function: function code L; Ribonuclease HI

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase H domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR012337
- InterPro:   IPR014636
- InterPro:   IPR002156 [H]

Pfam domain/function: PF00300 PGAM; PF00075 RnaseH [H]

EC number: NA

Molecular weight: Translated: 15539; Mature: 15407

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: PS50879 RNASE_H

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTKDTTFVYCDGSSRGNPGPAAIGVSFQNNEGMEFHFLSEKIGNATNNVAEWNALSRGM
CCCCCCEEEEECCCCCCCCCCEEEEEEEECCCCCEEEEHHHHHCCCCCCHHHHHHHHHHH
EEAIRQSIKKIKFRLDSELVVKQMKGEYKVKNKDLMVFKTKCDQLKNSFESFDIQYIPRE
HHHHHHHHHHHHHHCCHHHHHHHHCCCEEECCCCEEEEHHHHHHHHHHHHHCCEEECCCC
QNARADQLANFAQDSKP
CCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
STKDTTFVYCDGSSRGNPGPAAIGVSFQNNEGMEFHFLSEKIGNATNNVAEWNALSRGM
CCCCCEEEEECCCCCCCCCCEEEEEEEECCCCCEEEEHHHHHCCCCCCHHHHHHHHHHH
EEAIRQSIKKIKFRLDSELVVKQMKGEYKVKNKDLMVFKTKCDQLKNSFESFDIQYIPRE
HHHHHHHHHHHHHHCCHHHHHHHHCCCEEECCCCEEEEHHHHHHHHHHHHHCCEEECCCC
QNARADQLANFAQDSKP
CCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]