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The map label for this gene is yggV [C]

Identifier: 183222025

GI number: 183222025

Start: 2764769

End: 2765311

Strand: Reverse

Name: yggV [C]

Synonym: LEPBI_I2667

Alternate gene names: 183222025

Gene position: 2765311-2764769 (Counterclockwise)

Preceding gene: 183222026

Following gene: 183222024

Centisome position: 76.82

GC content: 38.67

Gene sequence:

>543_bases
ATGCAAATGTTACTCTCACCCTTCGGGTATGAAATTGTCACACCCAAAATTCTCGGAATTCCATTTTCTCCAGAAGAAAC
AGAATCCACATTTGTTGGAAATTCTTTTATCAAATCCAAAGAACTCTTTCGCCTAACAGGTTTTCCTTCGTTTGCAGATG
ATTCGGGGATCTCTGTGGATGCATTGGGTGGTGAACCTGGAGTCCTATCGGCAAGGTTTGGTGGGCCAGGGTTATCAGAT
AAAGATAGGGCATTGTATTTGCTAAATAAACTAGGAACCAATCATAATCGAAAGGCTCATTACTCTTGTGTGGTCAGTTT
TGTGGATGCGAACCATCAAGTTTCATTTGAAGGAAAAGTAGAAGGCCTCATTGCATCTGATTACGATGAATTGGGAAAAT
TTGGTTTTGGATATGATCCTATTTTTTATTACCCAGAGTTTGGGAAACGTTTTTCAGAAGTACCTGAAGGAGAGAAAAAC
AAAGTCTCTCATAGAAAAAAAGCGATGGAACTATTTTTGGAATGGTTTCAAACTATCCAATAA

Upstream 100 bases:

>100_bases
TTGCTTCCGCAATGGAAGGATTCCAACTCGACGAGGAAGATTCACACTGACAAAAAAAACATTAGCATTTGCATCTGGCA
GTGACCATAAAACGAAAGAA

Downstream 100 bases:

>100_bases
CGAATGTTACTCTAAAATTCCAATTGATTTTGGGAGCGATTACACTAGATCGGCATTGTACGAATAAAATCAGACATTGG
AATAGATGACAAAACCAGGT

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MQMLLSPFGYEIVTPKILGIPFSPEETESTFVGNSFIKSKELFRLTGFPSFADDSGISVDALGGEPGVLSARFGGPGLSD
KDRALYLLNKLGTNHNRKAHYSCVVSFVDANHQVSFEGKVEGLIASDYDELGKFGFGYDPIFYYPEFGKRFSEVPEGEKN
KVSHRKKAMELFLEWFQTIQ

Sequences:

>Translated_180_residues
MQMLLSPFGYEIVTPKILGIPFSPEETESTFVGNSFIKSKELFRLTGFPSFADDSGISVDALGGEPGVLSARFGGPGLSD
KDRALYLLNKLGTNHNRKAHYSCVVSFVDANHQVSFEGKVEGLIASDYDELGKFGFGYDPIFYYPEFGKRFSEVPEGEKN
KVSHRKKAMELFLEWFQTIQ
>Mature_180_residues
MQMLLSPFGYEIVTPKILGIPFSPEETESTFVGNSFIKSKELFRLTGFPSFADDSGISVDALGGEPGVLSARFGGPGLSD
KDRALYLLNKLGTNHNRKAHYSCVVSFVDANHQVSFEGKVEGLIASDYDELGKFGFGYDPIFYYPEFGKRFSEVPEGEKN
KVSHRKKAMELFLEWFQTIQ

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Escherichia coli, GI1789324, Length=182, Percent_Identity=36.2637362637363, Blast_Score=118, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_LEPBA (B0SE38)

Other databases:

- EMBL:   CP000777
- RefSeq:   YP_001963647.1
- ProteinModelPortal:   B0SE38
- SMR:   B0SE38
- GeneID:   6387391
- GenomeReviews:   CP000777_GR
- KEGG:   lbf:LBF_2585
- HOGENOM:   HBG697237
- OMA:   YSKRYDQ
- ProtClustDB:   PRK00120
- BioCyc:   LBIF355278:LBF_2585-MONOMER
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067
- TIGRFAMs:   TIGR00042

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 20097; Mature: 20097

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMLLSPFGYEIVTPKILGIPFSPEETESTFVGNSFIKSKELFRLTGFPSFADDSGISVD
CCCCCCCCCCEEECCEEEECCCCCCCCCCEECCCHHHHCCCEEEEECCCCCCCCCCCEEE
ALGGEPGVLSARFGGPGLSDKDRALYLLNKLGTNHNRKAHYSCVVSFVDANHQVSFEGKV
ECCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCHHHEEEEEEECCCCEEEECCCC
EGLIASDYDELGKFGFGYDPIFYYPEFGKRFSEVPEGEKNKVSHRKKAMELFLEWFQTIQ
CEEEECCHHHHHCCCCCCCCEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQMLLSPFGYEIVTPKILGIPFSPEETESTFVGNSFIKSKELFRLTGFPSFADDSGISVD
CCCCCCCCCCEEECCEEEECCCCCCCCCCEECCCHHHHCCCEEEEECCCCCCCCCCCEEE
ALGGEPGVLSARFGGPGLSDKDRALYLLNKLGTNHNRKAHYSCVVSFVDANHQVSFEGKV
ECCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCHHHEEEEEEECCCCEEEECCCC
EGLIASDYDELGKFGFGYDPIFYYPEFGKRFSEVPEGEKNKVSHRKKAMELFLEWFQTIQ
CEEEECCHHHHHCCCCCCCCEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA