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The map label for this gene is ybiT [H]

Identifier: 183222023

GI number: 183222023

Start: 2761964

End: 2763604

Strand: Direct

Name: ybiT [H]

Synonym: LEPBI_I2665

Alternate gene names: 183222023

Gene position: 2761964-2763604 (Clockwise)

Preceding gene: 183222019

Following gene: 183222029

Centisome position: 76.73

GC content: 44.24

Gene sequence:

>1641_bases
ATGATCCAAGCTAGCGGCATTACAGTCTCCTTCGGGAAAAAACCCCTTTTCGAAAACGTCTCCATCAAGTTCAAACCGGA
GTGCCGTTATGGGCTGATTGGAGCCAATGGTTCGGGGAAATCGACCTTTATGAAGGTCCTCGCGGGCATTTTACAGCCAT
CTGCGGGCTCCGTAGTCCTCGACAAGGACATCAAGGTGGGGTATTTGAAGCAGGACCACTATGAATACGAAAATGAGACC
GTTTTAGGGACTGTTTTACGGGGGAATCCAGAACTTTGGAGCCTCATGGCAGAACGGGATGCCATTTATGCCAAAGAAGA
CATGACGGACGAAGAAGGGATCCGTATTTCCGAAATTGAGGAGCTATTTGCCGATATGGGAGGCTACGAGGCCGAATCGG
TTGCTGGAGAGCTTTTGGAAGGACTCGGAATCCCAACCACTGCGCACAGCCGCCCACTTAATTTTTTAACTGGTGGATTC
AAATTACGGGTTCTCCTTGCCCAAGTTCTCTTTTTAAAACCAGATGTCCTTCTCCTTGACGAACCAACAAACCACTTGGA
TATCAAAACCATCCACTGGCTCGAGGAACTTCTCACGAATTATGAAGGTGTGGTGATTGTCATCTCCCACGACCGTCACT
TTATCAATTCCGTGGCAACCCATATTGCCGACTTAGATTATAATACCATCCGAGTTTTCCCAGGAAATTACGACGATTTT
ATGATCGCCGCAGAGCAGTCACGCGAACAACTTATGAGTGATAGCAAACGTGCAAAAGAAAAAATTGCCGACTTACAAGA
GTTTGTTTCAAGGTTCTCCGCCAATGCAAGTAAATCCAAACAGGCGACCTCTCGTCAAAAGATGATCGAAAAAATCAAAG
CTGATATGGTGGATGTGAAACCTTCCTCCCGTGTTGCACCTTACATTCGTTTTAAGGCAAAACGAGTTTTGGGAAAGGAT
GTATTTGAAGCCATCAATGTCTCCAAGTCTTATGATGGAAAGCCCGTCATCAAAGACTTTAGTATCTCCATCACCAAAGG
GGAAAAAGTGGGAATTGTGGGTACAAACGGTGTAGGAAAAACGACTCTTCTCAAAATGTTATTAAAAAAATTAGAACCGG
ATTCAGGACAAGTGAAATGGGGAGATTCAGTCGAAACTTCCTTTTTTCCACAAGACCACCGTGAGGCGATGGAACCTGAT
GCTGACACACTTGTGGAATGGTTACTCCGAAACTCACCGCAAGGAACAGAAGTACAAGAAATTCGTGCCATCTTAGGAAG
GATGTTATTTTCAGGAGACATGGCAAACAAATCCACTACGGTTTTGTCTGGAGGCGAAAAATCAAGGATGATCATTGGAA
AAATGATCCTTGCTTGCGACAATGTCATTGCACTCGATGAACCTACAAACCACTTAGACTTAGAAACCATTGAGGCATTA
AACTACGCTTTATCATTGTTTGATGGAACTGTGATCCTTGTTTCGCACGATAGGGAGTTTATTTCCTCACTTTGTACACG
GATCATTGAAGTGACTCCAGAAGGAATCAATGACTTCAAAGGGAATTACGAAGAATTTTTGGAACGAGAAGGAAGTGATT
TTTACAAACGGCTCACTGGAGGAGCGATTCTTTCGACTTAA

Upstream 100 bases:

>100_bases
GTGAGCCCGCTCCCAAAAAGGAAGAGAATGATGAGAAGAATCCGTGCCATACCATACGAAATGTCGGTTGAAACCTCCGA
TTCCCTTAGAAAATTGACCT

Downstream 100 bases:

>100_bases
AATTGATAATTCAGGGAGAGATTCGCGGATTGCATCTCTCTCCCTGCCATCAGTTCCGTTGTCACACTAAAATTCCCCTG
CCCTAATCGAAATCCCAAAC

Product: ABC transporter ATP-binding component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MIQASGITVSFGKKPLFENVSIKFKPECRYGLIGANGSGKSTFMKVLAGILQPSAGSVVLDKDIKVGYLKQDHYEYENET
VLGTVLRGNPELWSLMAERDAIYAKEDMTDEEGIRISEIEELFADMGGYEAESVAGELLEGLGIPTTAHSRPLNFLTGGF
KLRVLLAQVLFLKPDVLLLDEPTNHLDIKTIHWLEELLTNYEGVVIVISHDRHFINSVATHIADLDYNTIRVFPGNYDDF
MIAAEQSREQLMSDSKRAKEKIADLQEFVSRFSANASKSKQATSRQKMIEKIKADMVDVKPSSRVAPYIRFKAKRVLGKD
VFEAINVSKSYDGKPVIKDFSISITKGEKVGIVGTNGVGKTTLLKMLLKKLEPDSGQVKWGDSVETSFFPQDHREAMEPD
ADTLVEWLLRNSPQGTEVQEIRAILGRMLFSGDMANKSTTVLSGGEKSRMIIGKMILACDNVIALDEPTNHLDLETIEAL
NYALSLFDGTVILVSHDREFISSLCTRIIEVTPEGINDFKGNYEEFLEREGSDFYKRLTGGAILST

Sequences:

>Translated_546_residues
MIQASGITVSFGKKPLFENVSIKFKPECRYGLIGANGSGKSTFMKVLAGILQPSAGSVVLDKDIKVGYLKQDHYEYENET
VLGTVLRGNPELWSLMAERDAIYAKEDMTDEEGIRISEIEELFADMGGYEAESVAGELLEGLGIPTTAHSRPLNFLTGGF
KLRVLLAQVLFLKPDVLLLDEPTNHLDIKTIHWLEELLTNYEGVVIVISHDRHFINSVATHIADLDYNTIRVFPGNYDDF
MIAAEQSREQLMSDSKRAKEKIADLQEFVSRFSANASKSKQATSRQKMIEKIKADMVDVKPSSRVAPYIRFKAKRVLGKD
VFEAINVSKSYDGKPVIKDFSISITKGEKVGIVGTNGVGKTTLLKMLLKKLEPDSGQVKWGDSVETSFFPQDHREAMEPD
ADTLVEWLLRNSPQGTEVQEIRAILGRMLFSGDMANKSTTVLSGGEKSRMIIGKMILACDNVIALDEPTNHLDLETIEAL
NYALSLFDGTVILVSHDREFISSLCTRIIEVTPEGINDFKGNYEEFLEREGSDFYKRLTGGAILST
>Mature_546_residues
MIQASGITVSFGKKPLFENVSIKFKPECRYGLIGANGSGKSTFMKVLAGILQPSAGSVVLDKDIKVGYLKQDHYEYENET
VLGTVLRGNPELWSLMAERDAIYAKEDMTDEEGIRISEIEELFADMGGYEAESVAGELLEGLGIPTTAHSRPLNFLTGGF
KLRVLLAQVLFLKPDVLLLDEPTNHLDIKTIHWLEELLTNYEGVVIVISHDRHFINSVATHIADLDYNTIRVFPGNYDDF
MIAAEQSREQLMSDSKRAKEKIADLQEFVSRFSANASKSKQATSRQKMIEKIKADMVDVKPSSRVAPYIRFKAKRVLGKD
VFEAINVSKSYDGKPVIKDFSISITKGEKVGIVGTNGVGKTTLLKMLLKKLEPDSGQVKWGDSVETSFFPQDHREAMEPD
ADTLVEWLLRNSPQGTEVQEIRAILGRMLFSGDMANKSTTVLSGGEKSRMIIGKMILACDNVIALDEPTNHLDLETIEAL
NYALSLFDGTVILVSHDREFISSLCTRIIEVTPEGINDFKGNYEEFLEREGSDFYKRLTGGAILST

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=531, Percent_Identity=32.391713747646, Blast_Score=276, Evalue=4e-74,
Organism=Homo sapiens, GI10947137, Length=541, Percent_Identity=30.4990757855823, Blast_Score=238, Evalue=1e-62,
Organism=Homo sapiens, GI27881506, Length=541, Percent_Identity=30.4990757855823, Blast_Score=238, Evalue=1e-62,
Organism=Homo sapiens, GI10947135, Length=543, Percent_Identity=29.4659300184162, Blast_Score=211, Evalue=2e-54,
Organism=Homo sapiens, GI69354671, Length=543, Percent_Identity=29.4659300184162, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI27262624, Length=237, Percent_Identity=26.1603375527426, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI27262626, Length=237, Percent_Identity=26.1603375527426, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1787041, Length=531, Percent_Identity=52.9190207156309, Blast_Score=596, Evalue=1e-171,
Organism=Escherichia coli, GI1789751, Length=529, Percent_Identity=32.1361058601134, Blast_Score=295, Evalue=4e-81,
Organism=Escherichia coli, GI2367384, Length=548, Percent_Identity=32.6642335766423, Blast_Score=267, Evalue=1e-72,
Organism=Escherichia coli, GI1787182, Length=550, Percent_Identity=32.7272727272727, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI145693107, Length=527, Percent_Identity=22.7703984819734, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1788165, Length=181, Percent_Identity=30.939226519337, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788897, Length=523, Percent_Identity=22.5621414913958, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87081791, Length=222, Percent_Identity=27.4774774774775, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1787029, Length=233, Percent_Identity=27.4678111587983, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787758, Length=208, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081782, Length=220, Percent_Identity=29.0909090909091, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788225, Length=220, Percent_Identity=26.8181818181818, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790739, Length=225, Percent_Identity=27.5555555555556, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788761, Length=221, Percent_Identity=23.5294117647059, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082267, Length=229, Percent_Identity=26.6375545851528, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1787112, Length=218, Percent_Identity=27.0642201834862, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1787370, Length=201, Percent_Identity=26.3681592039801, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=551, Percent_Identity=33.7568058076225, Blast_Score=279, Evalue=3e-75,
Organism=Caenorhabditis elegans, GI17555318, Length=535, Percent_Identity=30.4672897196262, Blast_Score=240, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI17559834, Length=544, Percent_Identity=28.6764705882353, Blast_Score=231, Evalue=5e-61,
Organism=Caenorhabditis elegans, GI17558664, Length=203, Percent_Identity=27.0935960591133, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115533608, Length=202, Percent_Identity=28.2178217821782, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71992285, Length=226, Percent_Identity=27.4336283185841, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=536, Percent_Identity=31.9029850746269, Blast_Score=248, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6320874, Length=539, Percent_Identity=29.4990723562152, Blast_Score=227, Evalue=4e-60,
Organism=Saccharomyces cerevisiae, GI6325030, Length=414, Percent_Identity=23.6714975845411, Blast_Score=113, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6323278, Length=395, Percent_Identity=24.3037974683544, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324314, Length=386, Percent_Identity=24.0932642487047, Blast_Score=107, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24666836, Length=538, Percent_Identity=32.8996282527881, Blast_Score=271, Evalue=7e-73,
Organism=Drosophila melanogaster, GI24642252, Length=535, Percent_Identity=30.8411214953271, Blast_Score=254, Evalue=9e-68,
Organism=Drosophila melanogaster, GI18859989, Length=535, Percent_Identity=30.8411214953271, Blast_Score=254, Evalue=9e-68,
Organism=Drosophila melanogaster, GI24641342, Length=545, Percent_Identity=29.1743119266055, Blast_Score=234, Evalue=8e-62,
Organism=Drosophila melanogaster, GI116007184, Length=182, Percent_Identity=28.021978021978, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221500365, Length=182, Percent_Identity=28.021978021978, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 60715; Mature: 60715

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQASGITVSFGKKPLFENVSIKFKPECRYGLIGANGSGKSTFMKVLAGILQPSAGSVVL
CEECCCCEEECCCCCCCCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEE
DKDIKVGYLKQDHYEYENETVLGTVLRGNPELWSLMAERDAIYAKEDMTDEEGIRISEIE
ECCCEEEEEECCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCEECCCCCCCCCCCHHHHH
ELFADMGGYEAESVAGELLEGLGIPTTAHSRPLNFLTGGFKLRVLLAQVLFLKPDVLLLD
HHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCEEEEE
EPTNHLDIKTIHWLEELLTNYEGVVIVISHDRHFINSVATHIADLDYNTIRVFPGNYDDF
CCCCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCCE
MIAAEQSREQLMSDSKRAKEKIADLQEFVSRFSANASKSKQATSRQKMIEKIKADMVDVK
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
PSSRVAPYIRFKAKRVLGKDVFEAINVSKSYDGKPVIKDFSISITKGEKVGIVGTNGVGK
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCEEEEEECCCCCH
TTLLKMLLKKLEPDSGQVKWGDSVETSFFPQDHREAMEPDADTLVEWLLRNSPQGTEVQE
HHHHHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCHHH
IRAILGRMLFSGDMANKSTTVLSGGEKSRMIIGKMILACDNVIALDEPTNHLDLETIEAL
HHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHH
NYALSLFDGTVILVSHDREFISSLCTRIIEVTPEGINDFKGNYEEFLEREGSDFYKRLTG
HHHHHHHCCEEEEEECCHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHCCCHHHHHHHCC
GAILST
CCCCCC
>Mature Secondary Structure
MIQASGITVSFGKKPLFENVSIKFKPECRYGLIGANGSGKSTFMKVLAGILQPSAGSVVL
CEECCCCEEECCCCCCCCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEE
DKDIKVGYLKQDHYEYENETVLGTVLRGNPELWSLMAERDAIYAKEDMTDEEGIRISEIE
ECCCEEEEEECCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCEECCCCCCCCCCCHHHHH
ELFADMGGYEAESVAGELLEGLGIPTTAHSRPLNFLTGGFKLRVLLAQVLFLKPDVLLLD
HHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCEEEEE
EPTNHLDIKTIHWLEELLTNYEGVVIVISHDRHFINSVATHIADLDYNTIRVFPGNYDDF
CCCCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCCE
MIAAEQSREQLMSDSKRAKEKIADLQEFVSRFSANASKSKQATSRQKMIEKIKADMVDVK
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
PSSRVAPYIRFKAKRVLGKDVFEAINVSKSYDGKPVIKDFSISITKGEKVGIVGTNGVGK
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCEEEEEECCCCCH
TTLLKMLLKKLEPDSGQVKWGDSVETSFFPQDHREAMEPDADTLVEWLLRNSPQGTEVQE
HHHHHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCHHH
IRAILGRMLFSGDMANKSTTVLSGGEKSRMIIGKMILACDNVIALDEPTNHLDLETIEAL
HHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHH
NYALSLFDGTVILVSHDREFISSLCTRIIEVTPEGINDFKGNYEEFLEREGSDFYKRLTG
HHHHHHHCCEEEEEECCHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHCCCHHHHHHHCC
GAILST
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]