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The map label for this gene is ucpA [C]

Identifier: 183222000

GI number: 183222000

Start: 2734130

End: 2734987

Strand: Reverse

Name: ucpA [C]

Synonym: LEPBI_I2641

Alternate gene names: 183222000

Gene position: 2734987-2734130 (Counterclockwise)

Preceding gene: 183222001

Following gene: 183221999

Centisome position: 75.98

GC content: 36.36

Gene sequence:

>858_bases
ATGAGTCAAACTATTTTAATCACAGGCGCAACAGACGGAATTGGAAGAGTTTGTGCTCATTCCTTTGCGAAATCAAAAAA
CGAACTCATATTAGTTGGAAGAAATCCCGAAAAACTTTCAGCATTAGTGTATAGTTTGCAAGTACACGGTGTAAATGCTC
ACTCCTATGTCGCGGATTTATCTTTAGCCAAAGAAACTTTCGCCGTTACTGAAAAGATTAGAAACGACCATTCTAAAATT
GATGTGCTTCTCAATAATGCAGGTGCTTATTTTGATAAACGTGTGGTCACAAAAGAAGGATTAGAATCTACATTCGCTTT
GAACCATTTGAATTATTATATCATGGCATTAGGATTGTTACCATCGTTAAAAAATGCAAACCAAGCTCGTATCATAAACG
TTGCTTCTCGTGCTCATGAAGGAGTGGCGTTGGATTTTAATGACATCTTGGCTGAAACCAATTACTCGGGATGGAAACAA
TACCAAAGATCCAAATTGATGAATATATATTTTACCTACGAATTGGCCGAAAGACTCAACCAAACAAAGATTACTGTGAA
TTGTTTGCATCCTGGGTTCGTAAAAACCAAATTTGGTCAAAACAATGATGGATTGGCTAAAGTCGTTTTAACATTCGCAC
AGAATATATTTGCGATTTCTGAGGAAAAAGGTGCGGAAACTTCCATCTATTTGGCAACGGAACCGAGTTTAAGCAGTGTT
ACTGGTAAGTATTTTGTGAAAAAGAAAGAACGGAACAGTTCACCCGTTTCCTATGATAAAACCACTCGAAGGAATTTATG
GACTTATACAGAAGATCTTCTCAAACACAAATTTTCTTTTAAATTTCCTGGTAACTAA

Upstream 100 bases:

>100_bases
TGACAGTGAATGGTGGAACACTTTCTGCAGACAGTGATGGAGCCTCAGGTTCTGTATTTCAATTTAGCATCCCCAAAAAA
CAAAACGAGGAAGTTTTTAT

Downstream 100 bases:

>100_bases
CGTGGGTTACTTACACCAAAAAAATCCAACAGTGATTCCCGTTCCTGGAAATAAAACGATTGAAGAACACTTTGGGATCC
CCTCAACAAATACAAATGAA

Product: putative short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MSQTILITGATDGIGRVCAHSFAKSKNELILVGRNPEKLSALVYSLQVHGVNAHSYVADLSLAKETFAVTEKIRNDHSKI
DVLLNNAGAYFDKRVVTKEGLESTFALNHLNYYIMALGLLPSLKNANQARIINVASRAHEGVALDFNDILAETNYSGWKQ
YQRSKLMNIYFTYELAERLNQTKITVNCLHPGFVKTKFGQNNDGLAKVVLTFAQNIFAISEEKGAETSIYLATEPSLSSV
TGKYFVKKKERNSSPVSYDKTTRRNLWTYTEDLLKHKFSFKFPGN

Sequences:

>Translated_285_residues
MSQTILITGATDGIGRVCAHSFAKSKNELILVGRNPEKLSALVYSLQVHGVNAHSYVADLSLAKETFAVTEKIRNDHSKI
DVLLNNAGAYFDKRVVTKEGLESTFALNHLNYYIMALGLLPSLKNANQARIINVASRAHEGVALDFNDILAETNYSGWKQ
YQRSKLMNIYFTYELAERLNQTKITVNCLHPGFVKTKFGQNNDGLAKVVLTFAQNIFAISEEKGAETSIYLATEPSLSSV
TGKYFVKKKERNSSPVSYDKTTRRNLWTYTEDLLKHKFSFKFPGN
>Mature_284_residues
SQTILITGATDGIGRVCAHSFAKSKNELILVGRNPEKLSALVYSLQVHGVNAHSYVADLSLAKETFAVTEKIRNDHSKID
VLLNNAGAYFDKRVVTKEGLESTFALNHLNYYIMALGLLPSLKNANQARIINVASRAHEGVALDFNDILAETNYSGWKQY
QRSKLMNIYFTYELAERLNQTKITVNCLHPGFVKTKFGQNNDGLAKVVLTFAQNIFAISEEKGAETSIYLATEPSLSSVT
GKYFVKKKERNSSPVSYDKTTRRNLWTYTEDLLKHKFSFKFPGN

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI10190746, Length=291, Percent_Identity=32.9896907216495, Blast_Score=147, Evalue=9e-36,
Organism=Homo sapiens, GI225579078, Length=279, Percent_Identity=32.9749103942652, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI186928839, Length=274, Percent_Identity=31.3868613138686, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI7706523, Length=288, Percent_Identity=30.5555555555556, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI19923931, Length=231, Percent_Identity=33.7662337662338, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI166795268, Length=274, Percent_Identity=29.9270072992701, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI193804850, Length=279, Percent_Identity=30.1075268817204, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI146231950, Length=278, Percent_Identity=28.4172661870504, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI210032110, Length=206, Percent_Identity=30.5825242718447, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI142976729, Length=204, Percent_Identity=30.8823529411765, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI72534732, Length=155, Percent_Identity=34.1935483870968, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI13375997, Length=178, Percent_Identity=30.8988764044944, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI32483357, Length=201, Percent_Identity=26.3681592039801, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI87082100, Length=204, Percent_Identity=26.4705882352941, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787820, Length=243, Percent_Identity=26.3374485596708, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115533172, Length=278, Percent_Identity=32.3741007194245, Blast_Score=120, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI115533174, Length=283, Percent_Identity=32.1554770318021, Blast_Score=120, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17558006, Length=284, Percent_Identity=30.2816901408451, Blast_Score=118, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI72001364, Length=285, Percent_Identity=29.8245614035088, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17532805, Length=287, Percent_Identity=27.8745644599303, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17532791, Length=291, Percent_Identity=26.1168384879725, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI193207620, Length=287, Percent_Identity=25.4355400696864, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI193203117, Length=185, Percent_Identity=29.7297297297297, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=185, Percent_Identity=29.7297297297297, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17505416, Length=291, Percent_Identity=25.7731958762887, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17540960, Length=213, Percent_Identity=26.2910798122066, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71992402, Length=285, Percent_Identity=23.1578947368421, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=253, Percent_Identity=27.6679841897233, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=204, Percent_Identity=30.8823529411765, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24586328, Length=281, Percent_Identity=32.0284697508897, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI45554248, Length=274, Percent_Identity=30.2919708029197, Blast_Score=131, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24640117, Length=274, Percent_Identity=30.2919708029197, Blast_Score=131, Evalue=7e-31,
Organism=Drosophila melanogaster, GI22024069, Length=275, Percent_Identity=30.5454545454545, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI161076371, Length=279, Percent_Identity=30.4659498207885, Blast_Score=124, Evalue=7e-29,
Organism=Drosophila melanogaster, GI19921754, Length=278, Percent_Identity=30.5755395683453, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24647946, Length=276, Percent_Identity=31.8840579710145, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI45553409, Length=276, Percent_Identity=31.8840579710145, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24647948, Length=276, Percent_Identity=31.8840579710145, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28573296, Length=274, Percent_Identity=29.9270072992701, Blast_Score=118, Evalue=5e-27,
Organism=Drosophila melanogaster, GI20129347, Length=282, Percent_Identity=30.1418439716312, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24647931, Length=299, Percent_Identity=29.4314381270903, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24656154, Length=279, Percent_Identity=27.9569892473118, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI19922628, Length=279, Percent_Identity=27.9569892473118, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24643142, Length=205, Percent_Identity=29.7560975609756, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI23397609, Length=201, Percent_Identity=29.3532338308458, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31931; Mature: 31800

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTILITGATDGIGRVCAHSFAKSKNELILVGRNPEKLSALVYSLQVHGVNAHSYVADL
CCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHEEEEEEECCCHHHHHHHH
SLAKETFAVTEKIRNDHSKIDVLLNNAGAYFDKRVVTKEGLESTFALNHLNYYIMALGLL
HHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
PSLKNANQARIINVASRAHEGVALDFNDILAETNYSGWKQYQRSKLMNIYFTYELAERLN
CCCCCCCCEEEEEEHHHCCCCEEEEHHHHHHCCCCHHHHHHHHHHHEEEEEEEHHHHHCC
QTKITVNCLHPGFVKTKFGQNNDGLAKVVLTFAQNIFAISEEKGAETSIYLATEPSLSSV
CCEEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHEEEECCCCCCEEEEEEECCCHHHC
TGKYFVKKKERNSSPVSYDKTTRRNLWTYTEDLLKHKFSFKFPGN
CHHHEEEECCCCCCCCCCCCHHHCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SQTILITGATDGIGRVCAHSFAKSKNELILVGRNPEKLSALVYSLQVHGVNAHSYVADL
CCEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHEEEEEEECCCHHHHHHHH
SLAKETFAVTEKIRNDHSKIDVLLNNAGAYFDKRVVTKEGLESTFALNHLNYYIMALGLL
HHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
PSLKNANQARIINVASRAHEGVALDFNDILAETNYSGWKQYQRSKLMNIYFTYELAERLN
CCCCCCCCEEEEEEHHHCCCCEEEEHHHHHHCCCCHHHHHHHHHHHEEEEEEEHHHHHCC
QTKITVNCLHPGFVKTKFGQNNDGLAKVVLTFAQNIFAISEEKGAETSIYLATEPSLSSV
CCEEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHEEEECCCCCCEEEEEEECCCHHHC
TGKYFVKKKERNSSPVSYDKTTRRNLWTYTEDLLKHKFSFKFPGN
CHHHEEEECCCCCCCCCCCCHHHCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]