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The map label for this gene is rpiB [H]

Identifier: 183221739

GI number: 183221739

Start: 2439697

End: 2440134

Strand: Direct

Name: rpiB [H]

Synonym: LEPBI_I2368

Alternate gene names: 183221739

Gene position: 2439697-2440134 (Clockwise)

Preceding gene: 183221738

Following gene: 183221740

Centisome position: 67.78

GC content: 46.35

Gene sequence:

>438_bases
ATGAAAGAAAAAATTGGAATCGCCACTGATCATGGAGGATTTGCTCTGAAAGAATTCCTCAGGAAAAGTCTCGAGGAAAC
GTATGAAATGGTCGATTACGGTACTAAGAGCGAAGAGTCCGTCGACTACCCAACCATCATTGGAGATGCCTGCCGAAAGG
TACTCTCAAATGAAGTCCCACGACTCATCGCTCTCTGCGGAACGGGCATTGGAGCTTCCATTGCGGCGAACCGAATGAAA
GGCATTCGAGCGGCCCTTTGCCATGATGAGTTTACGGCAGAAATGTCGAGACGCCATAACAATGCCAATGTGTTGGTTTT
AGGGGGAAGAGTTCTTGGAACGGATTTAGCTCTGAGAATTGTGAAAAAATGGATCGAAACAGATTTCGAAGGTGGACGCC
ACCAAAAACGATTGGGTCTTATCGAAGAACAGTCTTAA

Upstream 100 bases:

>100_bases
GAAGTATGCTCCGAGAAAGGGATAAATTTTTGCTCTCCCTCTCCGTGGAAAGTTATGCGTCATACACCGAAGCCCTAAAA
CTAAGAAAGGAAAAATCCGA

Downstream 100 bases:

>100_bases
TCTCTCTTTGTTTCCTTTTTGGTGGCTCCTCTCTTTTATCATGGGAAGTTCCCAAAAAGGAAACCCTCAACCTTAGCCTT
TGGAAAAAAATTGGCGTCGT

Product: ribose-5-phosphate isomerase B

Products: D-ribulose 5-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MKEKIGIATDHGGFALKEFLRKSLEETYEMVDYGTKSEESVDYPTIIGDACRKVLSNEVPRLIALCGTGIGASIAANRMK
GIRAALCHDEFTAEMSRRHNNANVLVLGGRVLGTDLALRIVKKWIETDFEGGRHQKRLGLIEEQS

Sequences:

>Translated_145_residues
MKEKIGIATDHGGFALKEFLRKSLEETYEMVDYGTKSEESVDYPTIIGDACRKVLSNEVPRLIALCGTGIGASIAANRMK
GIRAALCHDEFTAEMSRRHNNANVLVLGGRVLGTDLALRIVKKWIETDFEGGRHQKRLGLIEEQS
>Mature_145_residues
MKEKIGIATDHGGFALKEFLRKSLEETYEMVDYGTKSEESVDYPTIIGDACRKVLSNEVPRLIALCGTGIGASIAANRMK
GIRAALCHDEFTAEMSRRHNNANVLVLGGRVLGTDLALRIVKKWIETDFEGGRHQKRLGLIEEQS

Specific function: In Addition To Its Activity On D-Ribose 5-Phosphate It Probably Also Has Activity On D-Allose 6-Phosphate. [C]

COG id: COG0698

COG function: function code G; Ribose 5-phosphate isomerase RpiB

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacAB/rpiB family [H]

Homologues:

Organism=Escherichia coli, GI1790528, Length=137, Percent_Identity=45.2554744525547, Blast_Score=125, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003500
- InterPro:   IPR004785 [H]

Pfam domain/function: PF02502 LacAB_rpiB [H]

EC number: 5.3.1.6

Molecular weight: Translated: 16049; Mature: 16049

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKIGIATDHGGFALKEFLRKSLEETYEMVDYGTKSEESVDYPTIIGDACRKVLSNEVP
CCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCHH
RLIALCGTGIGASIAANRMKGIRAALCHDEFTAEMSRRHNNANVLVLGGRVLGTDLALRI
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHH
VKKWIETDFEGGRHQKRLGLIEEQS
HHHHHHCCCCCCCHHHHHCCCCCCC
>Mature Secondary Structure
MKEKIGIATDHGGFALKEFLRKSLEETYEMVDYGTKSEESVDYPTIIGDACRKVLSNEVP
CCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCHH
RLIALCGTGIGASIAANRMKGIRAALCHDEFTAEMSRRHNNANVLVLGGRVLGTDLALRI
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHH
VKKWIETDFEGGRHQKRLGLIEEQS
HHHHHHCCCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 4.4 {D-ribose} 0.83 {D-ribose} [C]

Substrates: D-ribose 5-phosphate

Specific reaction: D-ribose 5-phosphate = D-ribulose 5-phosphate

General reaction: Intramolecular oxidoreduction; Isomerization [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]