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The map label for this gene is glnL [H]

Identifier: 183221461

GI number: 183221461

Start: 2172961

End: 2174661

Strand: Reverse

Name: glnL [H]

Synonym: LEPBI_I2079

Alternate gene names: 183221461

Gene position: 2174661-2172961 (Counterclockwise)

Preceding gene: 183221469

Following gene: 183221458

Centisome position: 60.41

GC content: 39.21

Gene sequence:

>1701_bases
ATGGATCGCTTTACAATCGAGCTCACACGTGCCAGGTTCCAGCAGAATATCTTGGCACAAGTCTCCTCCCATCCGTGTGC
TCGGACAGGAGACATCCAAACCTTGGCAGAGTTCATTACAAAATCAGTTTCTGATGTTTTGGAAATTGAACGGGTTGGGG
TTTGGCTCTTTAATGATTCTAAAAATGAACTCAAAAATATTGCCACCTACATACGGAGTAACGAGTCCCATACAACGGGA
GCCATTTTAAAGGAAAAAGAATTCCGCGAAGAGTTCCAATATTTGGTGAAAGAAAAATATGTGGATGCAAACGATCCCTA
TACCGATCCGCGCACCAAAGGATTTATTGAATCCTACCTCAAACCCAATGGAATCACGGCTATGTTAGATGGAGTGATCC
GGATGGGAGAAGAGCTAATCGGAACCCTCTGTTTTGAACATGTTGGAAAGATCCATGAATGGACGGAAGATGAAATCACA
TTCTGTAGTCAGTTAGGTGATCAAATAGCCCTCACCATCAGTAACAAAAGGAAAAATGAAATCAATGATGAACTCATTGC
CAGAGAAAATGAACTAAAGGAACTCAATGAAAGTTTGGAACGGCTAGTCGAAGAACGAACGAAAAAATTAAAAACATCGA
ATGAAGAATTAGAACAAACCATCTCTACCTTAAAAAAAGCACAAAACCAATTAGTGCTTTCTGAAAAAATGGCAAGCCTT
GGACAACTCGTAGCAGGGATTGCGCATGAGATCAATAATCCTATCGCCGCCATCCAAGCATCTGCTGAAAACTTGAAAGA
ATCTTTATTTGAATCGGAGCTTTCGGTTTTCCAAAAAGAATTGAAAGTACTGCTCCCCGATGACAAAAACCAGAAACAAT
TTTTGGAATGCATTCAAATCCTCAAATCGCGAATCGAAATCACCTCAGGGCGAGATCGAATGCAAAGAAGAAAACGAATC
GAAGCTTGGTTAGTGGACCAACATATCTCTGATTCTTTTTCCTTTCATCTGATCGATACTGGATTTGATTTGGATGTATT
GGATTTGTTTCCCCAGTTGTTTAGCGGAGAGAATTTAGAAGGAATCCTCAAATTTTTAGTTGAGGAAATCACTGTATACC
AATCCCTTCATATCATGTTACTTGCTGTCGAACGAGCGAGTAAAATGACATTTGCATTAAAAAACTTTGTACGTTATGAA
ATTTCGAAAGATCCGATCCAAGTGAATGTATTAGAAAACATTGAAACGGTTCTCACTTTATACCAAAATCAATTCAAAAA
AAATGTAATCCTAAAGAAGGATTTTGTGGAACTACCTTACATTGAAGGTTACCCAGAAGAATTATTACATCTATGGACCA
ATCTCATCTATAACGCACTGCAGGCGATGTCCTTTCAAGGGAAACTTTTGATCCAAACTAAAACTGATGGAAACAAGGTA
TTCATAATGGTAGAAGATAATGGACCAGGAATTCCGGAATTCATCCAGAACCGAATCTTTGAACCATTTTTTACAACAAA
ACCTCTGGGAGAAGGGAGTGGGCTTGGGCTCGATATCTGCCGTAAAATTGTAGACCGCCATTTTGGTTCGATCTCATTCC
AATCGATACCTGGGAAAACTGTCTTTACGATTGGTTTACCAGTAAAATCTCCAATTGATCATTCGAATCGTTCTCTACCA
CAAAACAGCAAAGAGGAATGA

Upstream 100 bases:

>100_bases
GGAGAAGGTGTAAGGGAAACCAGAGATTTTCGCAATTTTAGGAGTGACTTCTGTCTCTGCCTTTGTATGATTTTTCCACT
CCGATCTGTCTAAATTTCCC

Downstream 100 bases:

>100_bases
TTCTGGGATGGGACCAAGAGTTCTTGAGTCCACGCCGATTTCTCGGTTGTCAGCAAGTAAAAAGAAACTTTTTTCAGGTA
CGGTGACTTCCTTCATATCA

Product: putative two-component sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 566; Mature: 566

Protein sequence:

>566_residues
MDRFTIELTRARFQQNILAQVSSHPCARTGDIQTLAEFITKSVSDVLEIERVGVWLFNDSKNELKNIATYIRSNESHTTG
AILKEKEFREEFQYLVKEKYVDANDPYTDPRTKGFIESYLKPNGITAMLDGVIRMGEELIGTLCFEHVGKIHEWTEDEIT
FCSQLGDQIALTISNKRKNEINDELIARENELKELNESLERLVEERTKKLKTSNEELEQTISTLKKAQNQLVLSEKMASL
GQLVAGIAHEINNPIAAIQASAENLKESLFESELSVFQKELKVLLPDDKNQKQFLECIQILKSRIEITSGRDRMQRRKRI
EAWLVDQHISDSFSFHLIDTGFDLDVLDLFPQLFSGENLEGILKFLVEEITVYQSLHIMLLAVERASKMTFALKNFVRYE
ISKDPIQVNVLENIETVLTLYQNQFKKNVILKKDFVELPYIEGYPEELLHLWTNLIYNALQAMSFQGKLLIQTKTDGNKV
FIMVEDNGPGIPEFIQNRIFEPFFTTKPLGEGSGLGLDICRKIVDRHFGSISFQSIPGKTVFTIGLPVKSPIDHSNRSLP
QNSKEE

Sequences:

>Translated_566_residues
MDRFTIELTRARFQQNILAQVSSHPCARTGDIQTLAEFITKSVSDVLEIERVGVWLFNDSKNELKNIATYIRSNESHTTG
AILKEKEFREEFQYLVKEKYVDANDPYTDPRTKGFIESYLKPNGITAMLDGVIRMGEELIGTLCFEHVGKIHEWTEDEIT
FCSQLGDQIALTISNKRKNEINDELIARENELKELNESLERLVEERTKKLKTSNEELEQTISTLKKAQNQLVLSEKMASL
GQLVAGIAHEINNPIAAIQASAENLKESLFESELSVFQKELKVLLPDDKNQKQFLECIQILKSRIEITSGRDRMQRRKRI
EAWLVDQHISDSFSFHLIDTGFDLDVLDLFPQLFSGENLEGILKFLVEEITVYQSLHIMLLAVERASKMTFALKNFVRYE
ISKDPIQVNVLENIETVLTLYQNQFKKNVILKKDFVELPYIEGYPEELLHLWTNLIYNALQAMSFQGKLLIQTKTDGNKV
FIMVEDNGPGIPEFIQNRIFEPFFTTKPLGEGSGLGLDICRKIVDRHFGSISFQSIPGKTVFTIGLPVKSPIDHSNRSLP
QNSKEE
>Mature_566_residues
MDRFTIELTRARFQQNILAQVSSHPCARTGDIQTLAEFITKSVSDVLEIERVGVWLFNDSKNELKNIATYIRSNESHTTG
AILKEKEFREEFQYLVKEKYVDANDPYTDPRTKGFIESYLKPNGITAMLDGVIRMGEELIGTLCFEHVGKIHEWTEDEIT
FCSQLGDQIALTISNKRKNEINDELIARENELKELNESLERLVEERTKKLKTSNEELEQTISTLKKAQNQLVLSEKMASL
GQLVAGIAHEINNPIAAIQASAENLKESLFESELSVFQKELKVLLPDDKNQKQFLECIQILKSRIEITSGRDRMQRRKRI
EAWLVDQHISDSFSFHLIDTGFDLDVLDLFPQLFSGENLEGILKFLVEEITVYQSLHIMLLAVERASKMTFALKNFVRYE
ISKDPIQVNVLENIETVLTLYQNQFKKNVILKKDFVELPYIEGYPEELLHLWTNLIYNALQAMSFQGKLLIQTKTDGNKV
FIMVEDNGPGIPEFIQNRIFEPFFTTKPLGEGSGLGLDICRKIVDRHFGSISFQSIPGKTVFTIGLPVKSPIDHSNRSLP
QNSKEE

Specific function: NtrB acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC. In nitrogen limitation ntrB activates ntrC by phosphorylating it, while in nitrogen excess ntrC is dephosphorylated and consequently inactiva

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790300, Length=204, Percent_Identity=28.921568627451, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1788549, Length=181, Percent_Identity=35.3591160220994, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1790436, Length=112, Percent_Identity=41.0714285714286, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI145693157, Length=114, Percent_Identity=35.0877192982456, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 64846; Mature: 64846

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRFTIELTRARFQQNILAQVSSHPCARTGDIQTLAEFITKSVSDVLEIERVGVWLFNDS
CCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCC
KNELKNIATYIRSNESHTTGAILKEKEFREEFQYLVKEKYVDANDPYTDPRTKGFIESYL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHC
KPNGITAMLDGVIRMGEELIGTLCFEHVGKIHEWTEDEITFCSQLGDQIALTISNKRKNE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEEECCCCCCC
INDELIARENELKELNESLERLVEERTKKLKTSNEELEQTISTLKKAQNQLVLSEKMASL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQLVAGIAHEINNPIAAIQASAENLKESLFESELSVFQKELKVLLPDDKNQKQFLECIQI
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHH
LKSRIEITSGRDRMQRRKRIEAWLVDQHISDSFSFHLIDTGFDLDVLDLFPQLFSGENLE
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCHH
GILKFLVEEITVYQSLHIMLLAVERASKMTFALKNFVRYEISKDPIQVNVLENIETVLTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHH
YQNQFKKNVILKKDFVELPYIEGYPEELLHLWTNLIYNALQAMSFQGKLLIQTKTDGNKV
HHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEE
FIMVEDNGPGIPEFIQNRIFEPFFTTKPLGEGSGLGLDICRKIVDRHFGSISFQSIPGKT
EEEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCE
VFTIGLPVKSPIDHSNRSLPQNSKEE
EEEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDRFTIELTRARFQQNILAQVSSHPCARTGDIQTLAEFITKSVSDVLEIERVGVWLFNDS
CCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCC
KNELKNIATYIRSNESHTTGAILKEKEFREEFQYLVKEKYVDANDPYTDPRTKGFIESYL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHC
KPNGITAMLDGVIRMGEELIGTLCFEHVGKIHEWTEDEITFCSQLGDQIALTISNKRKNE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEEECCCCCCC
INDELIARENELKELNESLERLVEERTKKLKTSNEELEQTISTLKKAQNQLVLSEKMASL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQLVAGIAHEINNPIAAIQASAENLKESLFESELSVFQKELKVLLPDDKNQKQFLECIQI
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHH
LKSRIEITSGRDRMQRRKRIEAWLVDQHISDSFSFHLIDTGFDLDVLDLFPQLFSGENLE
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCHH
GILKFLVEEITVYQSLHIMLLAVERASKMTFALKNFVRYEISKDPIQVNVLENIETVLTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHH
YQNQFKKNVILKKDFVELPYIEGYPEELLHLWTNLIYNALQAMSFQGKLLIQTKTDGNKV
HHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEE
FIMVEDNGPGIPEFIQNRIFEPFFTTKPLGEGSGLGLDICRKIVDRHFGSISFQSIPGKT
EEEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCE
VFTIGLPVKSPIDHSNRSLPQNSKEE
EEEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]