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The map label for this gene is p20 [H]

Identifier: 183221416

GI number: 183221416

Start: 2115641

End: 2116192

Strand: Reverse

Name: p20 [H]

Synonym: LEPBI_I2034

Alternate gene names: 183221416

Gene position: 2116192-2115641 (Counterclockwise)

Preceding gene: 183221417

Following gene: 183221415

Centisome position: 58.79

GC content: 32.97

Gene sequence:

>552_bases
ATGAGTGTAAAATACCCAACAGGAAATAAAATTTATCTCAGGGATCTTCAGGTACAAGATGTTGGAGATCGCTACTATTC
CTGGTTAAGCGATCCAGAAATTAATCAATATATAGAAACAAGATTTCTTCTACAATCTAAGGATGTAATTGCAGATTTTG
TAAAATCAAAACAGGGCAGCACAAATGAGATTCTTTGGGCAATATGTGAGAAGGAAAACAATCGCCATATTGGAAATATT
AAACTTGGACCAATAAATTGGTATCACCGATTTGCGGATATTAGTTTGTTTATTGGTGAAAAGGATTGCTGGTTTAAAGG
ATATAGTTCTGAATCAATTTCTTTAGTCGTTGATTTTGCCTTTAATACATTAAATTTGCACAAGGTGAAAGCTGGAGCTT
ATTCTCCTAATCTCGGTTCAATTCGGTCGTTTGAAAAAAATGGATTTAGTCAAGAAGGATTATTAAAAAATCATTTTTAT
TCAAATGGAAGTTATGTTGATGGAGTGCTTCTTGGGCTTACCCGTGAAGATTATAAACTCAAACGTTTATAA

Upstream 100 bases:

>100_bases
TCGATTCCTATCATTCCGGAAAAAATTTCGAAGGAATCGATTATTCTAAATTTGCAATTTTTGACGAGAGTATTACCAAT
CCTTCCAAATGGAAACTCAA

Downstream 100 bases:

>100_bases
TCTTCAATAAATAGATTGTGCACTTATATTAAATACGATTCAGGAAATTTATGAAAGTAATTGCTATTATCCAGGCAAGA
TTGGGATCCACAAGGTTACC

Product: putative N-acetyltransferase

Products: Coenzyme A; H+; N8-Acetylspermidine [C]

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MSVKYPTGNKIYLRDLQVQDVGDRYYSWLSDPEINQYIETRFLLQSKDVIADFVKSKQGSTNEILWAICEKENNRHIGNI
KLGPINWYHRFADISLFIGEKDCWFKGYSSESISLVVDFAFNTLNLHKVKAGAYSPNLGSIRSFEKNGFSQEGLLKNHFY
SNGSYVDGVLLGLTREDYKLKRL

Sequences:

>Translated_183_residues
MSVKYPTGNKIYLRDLQVQDVGDRYYSWLSDPEINQYIETRFLLQSKDVIADFVKSKQGSTNEILWAICEKENNRHIGNI
KLGPINWYHRFADISLFIGEKDCWFKGYSSESISLVVDFAFNTLNLHKVKAGAYSPNLGSIRSFEKNGFSQEGLLKNHFY
SNGSYVDGVLLGLTREDYKLKRL
>Mature_182_residues
SVKYPTGNKIYLRDLQVQDVGDRYYSWLSDPEINQYIETRFLLQSKDVIADFVKSKQGSTNEILWAICEKENNRHIGNIK
LGPINWYHRFADISLFIGEKDCWFKGYSSESISLVVDFAFNTLNLHKVKAGAYSPNLGSIRSFEKNGFSQEGLLKNHFYS
NGSYVDGVLLGLTREDYKLKRL

Specific function: Regulates Polyamine Concentration By Their Degradation. Acts On Spermidine, Forming N(1)- And N(8)-Acetylspermidine. [C]

COG id: COG1670

COG function: function code J; Acetyltransferases, including N-acetylases of ribosomal proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181 [H]

Pfam domain/function: PF00583 Acetyltransf_1 [H]

EC number: 2.3.1.57 [C]

Molecular weight: Translated: 21109; Mature: 20978

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKYPTGNKIYLRDLQVQDVGDRYYSWLSDPEINQYIETRFLLQSKDVIADFVKSKQGS
CCCCCCCCCEEEEEEEEEEECCHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCC
TNEILWAICEKENNRHIGNIKLGPINWYHRFADISLFIGEKDCWFKGYSSESISLVVDFA
CCCEEEEEEECCCCCEECEEEECCCHHHHHEEEEEEEECCCCCEEECCCCCCEEEEEEEE
FNTLNLHKVKAGAYSPNLGSIRSFEKNGFSQEGLLKNHFYSNGSYVDGVLLGLTREDYKL
CCEEEEEEEECCCCCCCCCCHHHHHHCCCCCCCCHHHHCCCCCCEECEEEEECCCCCEEE
KRL
CCC
>Mature Secondary Structure 
SVKYPTGNKIYLRDLQVQDVGDRYYSWLSDPEINQYIETRFLLQSKDVIADFVKSKQGS
CCCCCCCCEEEEEEEEEEECCHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCC
TNEILWAICEKENNRHIGNIKLGPINWYHRFADISLFIGEKDCWFKGYSSESISLVVDFA
CCCEEEEEEECCCCCEECEEEECCCHHHHHEEEEEEEECCCCCEEECCCCCCEEEEEEEE
FNTLNLHKVKAGAYSPNLGSIRSFEKNGFSQEGLLKNHFYSNGSYVDGVLLGLTREDYKL
CCEEEEEEEECCCCCCCCCCHHHHHHCCCCCCCCHHHHCCCCCCEECEEEEECCCCCEEE
KRL
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; Spermidine [C]

Specific reaction: Acetyl-CoA + Spermidine --> Coenzyme A + H+ + N8-Acetylspermidine [C]

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2838827 [H]