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The map label for this gene is 183221103

Identifier: 183221103

GI number: 183221103

Start: 1788603

End: 1790180

Strand: Direct

Name: 183221103

Synonym: LEPBI_I1717

Alternate gene names: NA

Gene position: 1788603-1790180 (Clockwise)

Preceding gene: 183221102

Following gene: 183221104

Centisome position: 49.69

GC content: 38.21

Gene sequence:

>1578_bases
ATGATGAAAGAGAGACAAGCGGAACACCAAGAAGGTTGGGCCAGTCGTGTCGGTTTGATTTTAGCGGTTGCGAGTGGTGC
CATCGGGCTTGGGAATTTTTTACGGTTTCCTGGACAGGCGGCACAAAACGGTGGTGGTGCCTTTATGGTACCCTACATCA
TCAGTTTTCTCATATTGGGTATCCCCGTTTGTTTGGCAGAATGGACCATGGGAAGGATGGGTGGAAAACACGGTCATAGC
ACTCCTTTTATATTCCGTGAATACCTAAAAGGATTTCCATTACGATTATCAGGAACCATCGGTGTGATGATTTACGTATA
TTATGTTTTCATTGAATCCTGGTGTTTGGCATATGCTTATTATTTTTTAACTGGCCAAATGTCATTATCTGCGACCACAC
AAGCTGGTATGACAAAAGAAGCTTCTACATTTTTTATGAACCTGACGGGAGCATCAGAGAATGGATCTAGTTTTCATTCC
CCAATCATTGTCTTTTTTCTGATTTGTGTCTTATTTAATTTTTTTTTAGTGTATCGGGGATTATCCAAAGGTTTGGAAGC
ATTTGCAAAAATTGCAATGCCATTGATGGGGATATGTGCAACCATCATTTTAATTCGAGTCCTTACCATCCCTGGGATTG
AAAAAGGGCTTGCTGTGATGTGGAATCCAGATTGGTCCAAATTAACCGAACCAAAAGTTTGGATCAGTGCTGCAGGCCAG
ATTTTTTTCTCTTTATCAACAGGATTTGGAATTGCTCTCGTGTTTTCTAGTTTTCTGAAGAAAAAAGATGATGTTGTTTT
ATCAAGTTTGTCGTCTGCTTCGATCAATGAATTCGCAGAAGTTGTGTTTGGTGGAATGATTACCATCCCAGTTGCTTTTT
TATTCTTAGGAATGCAAGTAACATCCTTTGGGACTTTTGGGATGGGATTCATTGCCTTACCCTCTGTTTTTGGAATGATG
CCTGGTGGGGATTTTTTTGGTGGTCTTTGGTTTCTTGTACTTTTCCTAGCTGCCATCACCTCTTCTGTCACTATGTTACA
GCCAGGGATATTATTTCTAGAAGAAGGATTTCGAATGGGAAGGCGTAAGTCCTCATTGATGCTGTTTCTATTTACATTTG
TATTATGTTTACCGATTATTTACTTTAACAAAGATTTTGCGGCGCTTGATATCGCCGATTTTTATATTGGAACGATTATG
ATTTATATTTTGGCTTCCATTCAAATATTTGTCTATGTCTTTAAGATAGGTGTGGATAGAGGAGAAAAAGAGGCGAATGA
GGGAAGCTTGATCCCTTTCCCGAAACCGATTAAATTTGTTTTAAAATACATCACTCCTTGGTTTTTATTTTTTATTTTTG
TATCCTTTTGTTATATGAATTTGCCTGAATATTTAGATAAAATGAACCCCGAAGTGATGGGACTTCTTGCTGAAAATAAA
GGCCAAAATGTTGAGGATGCCAAAACAAAAGCTGTGATTGCCAGATCCGTTGTGATTGGACTTTTACTCATCTACGGTTT
TATATATTTTTTGGTCTCAAAAGCATTAGAACATAAAAAAGATAAGGTACTCACTTAA

Upstream 100 bases:

>100_bases
TAAATTGAAAATCAACAAAGCAAGGTCTCTCTGGCCTTGCTTTTTCTCACTTCCAGACAAAAAGATTTTGTCACATAATT
CCAAAACCATTCAATAGTCC

Downstream 100 bases:

>100_bases
ATGACGACACAAGCTGAACTCAATTGGCAAGGAATCCTGATTATGACTGTTTCTTTGGTTTCTGTGATTAGTTTAACTGT
TGTCTGTGTGATCCTTCTTT

Product: putative sodium and chloride dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MMKERQAEHQEGWASRVGLILAVASGAIGLGNFLRFPGQAAQNGGGAFMVPYIISFLILGIPVCLAEWTMGRMGGKHGHS
TPFIFREYLKGFPLRLSGTIGVMIYVYYVFIESWCLAYAYYFLTGQMSLSATTQAGMTKEASTFFMNLTGASENGSSFHS
PIIVFFLICVLFNFFLVYRGLSKGLEAFAKIAMPLMGICATIILIRVLTIPGIEKGLAVMWNPDWSKLTEPKVWISAAGQ
IFFSLSTGFGIALVFSSFLKKKDDVVLSSLSSASINEFAEVVFGGMITIPVAFLFLGMQVTSFGTFGMGFIALPSVFGMM
PGGDFFGGLWFLVLFLAAITSSVTMLQPGILFLEEGFRMGRRKSSLMLFLFTFVLCLPIIYFNKDFAALDIADFYIGTIM
IYILASIQIFVYVFKIGVDRGEKEANEGSLIPFPKPIKFVLKYITPWFLFFIFVSFCYMNLPEYLDKMNPEVMGLLAENK
GQNVEDAKTKAVIARSVVIGLLLIYGFIYFLVSKALEHKKDKVLT

Sequences:

>Translated_525_residues
MMKERQAEHQEGWASRVGLILAVASGAIGLGNFLRFPGQAAQNGGGAFMVPYIISFLILGIPVCLAEWTMGRMGGKHGHS
TPFIFREYLKGFPLRLSGTIGVMIYVYYVFIESWCLAYAYYFLTGQMSLSATTQAGMTKEASTFFMNLTGASENGSSFHS
PIIVFFLICVLFNFFLVYRGLSKGLEAFAKIAMPLMGICATIILIRVLTIPGIEKGLAVMWNPDWSKLTEPKVWISAAGQ
IFFSLSTGFGIALVFSSFLKKKDDVVLSSLSSASINEFAEVVFGGMITIPVAFLFLGMQVTSFGTFGMGFIALPSVFGMM
PGGDFFGGLWFLVLFLAAITSSVTMLQPGILFLEEGFRMGRRKSSLMLFLFTFVLCLPIIYFNKDFAALDIADFYIGTIM
IYILASIQIFVYVFKIGVDRGEKEANEGSLIPFPKPIKFVLKYITPWFLFFIFVSFCYMNLPEYLDKMNPEVMGLLAENK
GQNVEDAKTKAVIARSVVIGLLLIYGFIYFLVSKALEHKKDKVLT
>Mature_525_residues
MMKERQAEHQEGWASRVGLILAVASGAIGLGNFLRFPGQAAQNGGGAFMVPYIISFLILGIPVCLAEWTMGRMGGKHGHS
TPFIFREYLKGFPLRLSGTIGVMIYVYYVFIESWCLAYAYYFLTGQMSLSATTQAGMTKEASTFFMNLTGASENGSSFHS
PIIVFFLICVLFNFFLVYRGLSKGLEAFAKIAMPLMGICATIILIRVLTIPGIEKGLAVMWNPDWSKLTEPKVWISAAGQ
IFFSLSTGFGIALVFSSFLKKKDDVVLSSLSSASINEFAEVVFGGMITIPVAFLFLGMQVTSFGTFGMGFIALPSVFGMM
PGGDFFGGLWFLVLFLAAITSSVTMLQPGILFLEEGFRMGRRKSSLMLFLFTFVLCLPIIYFNKDFAALDIADFYIGTIM
IYILASIQIFVYVFKIGVDRGEKEANEGSLIPFPKPIKFVLKYITPWFLFFIFVSFCYMNLPEYLDKMNPEVMGLLAENK
GQNVEDAKTKAVIARSVVIGLLLIYGFIYFLVSKALEHKKDKVLT

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI289191377, Length=497, Percent_Identity=25.9557344064386, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI289191351, Length=497, Percent_Identity=25.9557344064386, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI4557046, Length=497, Percent_Identity=25.9557344064386, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI4507043, Length=384, Percent_Identity=27.34375, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI7657587, Length=417, Percent_Identity=27.0983213429257, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI21361581, Length=404, Percent_Identity=25.4950495049505, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI194018524, Length=293, Percent_Identity=29.6928327645051, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI171184408, Length=459, Percent_Identity=25.7080610021786, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI171184406, Length=459, Percent_Identity=25.7080610021786, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI171184404, Length=459, Percent_Identity=25.7080610021786, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI4507041, Length=516, Percent_Identity=24.8062015503876, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI51468073, Length=496, Percent_Identity=23.991935483871, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI188528618, Length=393, Percent_Identity=24.4274809160305, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI11181770, Length=297, Percent_Identity=29.2929292929293, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI197276623, Length=356, Percent_Identity=26.685393258427, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI54607094, Length=356, Percent_Identity=26.685393258427, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI92859670, Length=520, Percent_Identity=22.5, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI58219014, Length=297, Percent_Identity=26.9360269360269, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI33354281, Length=296, Percent_Identity=27.027027027027, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI134304856, Length=352, Percent_Identity=26.1363636363636, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI5032097, Length=355, Percent_Identity=26.1971830985915, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI67782317, Length=373, Percent_Identity=24.6648793565684, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI67782313, Length=373, Percent_Identity=24.6648793565684, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI67782315, Length=373, Percent_Identity=24.6648793565684, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI218563756, Length=290, Percent_Identity=26.2068965517241, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI289191353, Length=304, Percent_Identity=27.3026315789474, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI6005715, Length=411, Percent_Identity=22.6277372262774, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI12408638, Length=294, Percent_Identity=25.5102040816327, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI197276625, Length=171, Percent_Identity=28.0701754385965, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71995588, Length=475, Percent_Identity=25.4736842105263, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI133952791, Length=439, Percent_Identity=25.2847380410023, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI25146584, Length=515, Percent_Identity=24.4660194174757, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17555248, Length=425, Percent_Identity=24, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17554804, Length=457, Percent_Identity=22.9759299781182, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17569475, Length=395, Percent_Identity=22.7848101265823, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17535731, Length=389, Percent_Identity=24.9357326478149, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17542050, Length=131, Percent_Identity=32.0610687022901, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24762620, Length=483, Percent_Identity=28.3643892339545, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI221329674, Length=389, Percent_Identity=27.5064267352185, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24639514, Length=389, Percent_Identity=27.5064267352185, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI281365034, Length=465, Percent_Identity=25.3763440860215, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24661428, Length=396, Percent_Identity=27.020202020202, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI17136952, Length=472, Percent_Identity=22.4576271186441, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24639516, Length=299, Percent_Identity=29.4314381270903, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI45550877, Length=417, Percent_Identity=25.1798561151079, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI45551183, Length=417, Percent_Identity=25.1798561151079, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI19921352, Length=471, Percent_Identity=24.6284501061571, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24584353, Length=471, Percent_Identity=24.6284501061571, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI281364394, Length=472, Percent_Identity=22.4576271186441, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28574704, Length=472, Percent_Identity=22.4576271186441, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17136950, Length=472, Percent_Identity=22.4576271186441, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28574702, Length=472, Percent_Identity=22.4576271186441, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24582567, Length=449, Percent_Identity=24.7216035634744, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI45551088, Length=457, Percent_Identity=24.72647702407, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24652942, Length=457, Percent_Identity=24.72647702407, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281363702, Length=489, Percent_Identity=25.9713701431493, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24655079, Length=295, Percent_Identity=27.4576271186441, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI19921936, Length=379, Percent_Identity=25.5936675461741, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI281364136, Length=407, Percent_Identity=26.2899262899263, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281363700, Length=304, Percent_Identity=27.3026315789474, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24639853, Length=462, Percent_Identity=25.3246753246753, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24654186, Length=306, Percent_Identity=27.1241830065359, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24582569, Length=414, Percent_Identity=23.1884057971014, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 58211; Mature: 58211

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKERQAEHQEGWASRVGLILAVASGAIGLGNFLRFPGQAAQNGGGAFMVPYIISFLILG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHH
IPVCLAEWTMGRMGGKHGHSTPFIFREYLKGFPLRLSGTIGVMIYVYYVFIESWCLAYAY
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHH
YFLTGQMSLSATTQAGMTKEASTFFMNLTGASENGSSFHSPIIVFFLICVLFNFFLVYRG
HHHHCCCEECHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LSKGLEAFAKIAMPLMGICATIILIRVLTIPGIEKGLAVMWNPDWSKLTEPKVWISAAGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHCCCCHHHHHHCC
IFFSLSTGFGIALVFSSFLKKKDDVVLSSLSSASINEFAEVVFGGMITIPVAFLFLGMQV
EEEEECCCHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSFGTFGMGFIALPSVFGMMPGGDFFGGLWFLVLFLAAITSSVTMLQPGILFLEEGFRMG
HHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHC
RRKSSLMLFLFTFVLCLPIIYFNKDFAALDIADFYIGTIMIYILASIQIFVYVFKIGVDR
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GEKEANEGSLIPFPKPIKFVLKYITPWFLFFIFVSFCYMNLPEYLDKMNPEVMGLLAENK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHCCC
GQNVEDAKTKAVIARSVVIGLLLIYGFIYFLVSKALEHKKDKVLT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MMKERQAEHQEGWASRVGLILAVASGAIGLGNFLRFPGQAAQNGGGAFMVPYIISFLILG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHH
IPVCLAEWTMGRMGGKHGHSTPFIFREYLKGFPLRLSGTIGVMIYVYYVFIESWCLAYAY
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHH
YFLTGQMSLSATTQAGMTKEASTFFMNLTGASENGSSFHSPIIVFFLICVLFNFFLVYRG
HHHHCCCEECHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LSKGLEAFAKIAMPLMGICATIILIRVLTIPGIEKGLAVMWNPDWSKLTEPKVWISAAGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHCCCCHHHHHHCC
IFFSLSTGFGIALVFSSFLKKKDDVVLSSLSSASINEFAEVVFGGMITIPVAFLFLGMQV
EEEEECCCHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSFGTFGMGFIALPSVFGMMPGGDFFGGLWFLVLFLAAITSSVTMLQPGILFLEEGFRMG
HHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHC
RRKSSLMLFLFTFVLCLPIIYFNKDFAALDIADFYIGTIMIYILASIQIFVYVFKIGVDR
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GEKEANEGSLIPFPKPIKFVLKYITPWFLFFIFVSFCYMNLPEYLDKMNPEVMGLLAENK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHCCC
GQNVEDAKTKAVIARSVVIGLLLIYGFIYFLVSKALEHKKDKVLT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]