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The map label for this gene is coaE [H]

Identifier: 183220838

GI number: 183220838

Start: 1513685

End: 1514302

Strand: Reverse

Name: coaE [H]

Synonym: LEPBI_I1450

Alternate gene names: 183220838

Gene position: 1514302-1513685 (Counterclockwise)

Preceding gene: 183220839

Following gene: 183220837

Centisome position: 42.07

GC content: 41.1

Gene sequence:

>618_bases
GTGGCACTTGCTCCAAACAAAACATTAATCGGTATTACCGGCTCCATTGGATCCGGGAAATCCACTGCGCTTTCCATCTT
TGGAGAATTAGGTGCAGTGACGATTAGTTCTGATACAATTGCCAGAAGTTTCACAGAACCAAATAGCCCTGTCAAATCCG
AACTCGTTTCGATCTTTGGACCATCGATTGTCTCAGAAAATGATACAATCAATCGCACAAAAATCGCAGAACTTGCTTTT
AGCGACGAAACAAAACTAAAAGCACTCAATGAACTCCTCCACCCACTCGTAAGAAAACAATTCCTGGAATTTTTCCAAGG
AACGAAGGAAGGGAGTCTCGTCGCCTGGGAAGTCCCACTTTTATTTGAAACCGATGCTCATACCATTTGTGATTTTACAG
TCACAATTTCCCTTCCCAAAGAACAAAACTGGGATCGTGTGAAAGTAAGGGGTGGGATGGACAAAGCCGATTTCGAAAGA
AGGACCGCTTCCCAAATGGACATCGAGAAAAAAAAGATCCTCTCTGATTTTGTCGTAACGAACGATACTGATAGAGAAGG
GTTAAAAGAACAAATCGTTATTATCTATAAGGAAATTCAAAAAAGGATTCAAAAATGA

Upstream 100 bases:

>100_bases
TCAGTAAACAAAGATTAAGTACAAAATCCTTTAGTATTTTTTTTCTCAAATGAAGTAAAAAAATACTTGTACTTTCACGG
GTTTTTTATGTTATAAACCC

Downstream 100 bases:

>100_bases
AAGAGAGAGTATTTTACGTAATCAATTTAGACAAACAAAGGATTGGAGTTCTATCACTCTTTCTTTTCGCCCTATTCTTT
TCTATTTTTTTCTTAGGCGT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MALAPNKTLIGITGSIGSGKSTALSIFGELGAVTISSDTIARSFTEPNSPVKSELVSIFGPSIVSENDTINRTKIAELAF
SDETKLKALNELLHPLVRKQFLEFFQGTKEGSLVAWEVPLLFETDAHTICDFTVTISLPKEQNWDRVKVRGGMDKADFER
RTASQMDIEKKKILSDFVVTNDTDREGLKEQIVIIYKEIQKRIQK

Sequences:

>Translated_205_residues
MALAPNKTLIGITGSIGSGKSTALSIFGELGAVTISSDTIARSFTEPNSPVKSELVSIFGPSIVSENDTINRTKIAELAF
SDETKLKALNELLHPLVRKQFLEFFQGTKEGSLVAWEVPLLFETDAHTICDFTVTISLPKEQNWDRVKVRGGMDKADFER
RTASQMDIEKKKILSDFVVTNDTDREGLKEQIVIIYKEIQKRIQK
>Mature_204_residues
ALAPNKTLIGITGSIGSGKSTALSIFGELGAVTISSDTIARSFTEPNSPVKSELVSIFGPSIVSENDTINRTKIAELAFS
DETKLKALNELLHPLVRKQFLEFFQGTKEGSLVAWEVPLLFETDAHTICDFTVTISLPKEQNWDRVKVRGGMDKADFERR
TASQMDIEKKKILSDFVVTNDTDREGLKEQIVIIYKEIQKRIQK

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=202, Percent_Identity=28.2178217821782, Blast_Score=110, Evalue=6e-25,
Organism=Homo sapiens, GI191252795, Length=202, Percent_Identity=28.2178217821782, Blast_Score=110, Evalue=6e-25,
Organism=Homo sapiens, GI110227607, Length=199, Percent_Identity=27.1356783919598, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI110227605, Length=199, Percent_Identity=27.1356783919598, Blast_Score=71, Evalue=5e-13,
Organism=Homo sapiens, GI110227603, Length=199, Percent_Identity=27.1356783919598, Blast_Score=71, Evalue=5e-13,
Organism=Homo sapiens, GI110227601, Length=199, Percent_Identity=27.1356783919598, Blast_Score=71, Evalue=5e-13,
Organism=Homo sapiens, GI205277394, Length=199, Percent_Identity=27.1356783919598, Blast_Score=71, Evalue=6e-13,
Organism=Escherichia coli, GI1786292, Length=192, Percent_Identity=26.5625, Blast_Score=88, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17554944, Length=200, Percent_Identity=31.5, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6320402, Length=202, Percent_Identity=29.2079207920792, Blast_Score=94, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24644728, Length=195, Percent_Identity=29.7435897435897, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24658602, Length=205, Percent_Identity=26.3414634146341, Blast_Score=80, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22820; Mature: 22689

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALAPNKTLIGITGSIGSGKSTALSIFGELGAVTISSDTIARSFTEPNSPVKSELVSIFG
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHCEEEECCCHHHHHCCCCCCHHHHHHHHHHC
PSIVSENDTINRTKIAELAFSDETKLKALNELLHPLVRKQFLEFFQGTKEGSLVAWEVPL
CCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECE
LFETDAHTICDFTVTISLPKEQNWDRVKVRGGMDKADFERRTASQMDIEKKKILSDFVVT
EEECCCCEEEEEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
NDTDREGLKEQIVIIYKEIQKRIQK
CCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALAPNKTLIGITGSIGSGKSTALSIFGELGAVTISSDTIARSFTEPNSPVKSELVSIFG
CCCCCCEEEEEECCCCCCCHHHHHHHHHHCEEEECCCHHHHHCCCCCCHHHHHHHHHHC
PSIVSENDTINRTKIAELAFSDETKLKALNELLHPLVRKQFLEFFQGTKEGSLVAWEVPL
CCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECE
LFETDAHTICDFTVTISLPKEQNWDRVKVRGGMDKADFERRTASQMDIEKKKILSDFVVT
EEECCCCEEEEEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
NDTDREGLKEQIVIIYKEIQKRIQK
CCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA