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The map label for this gene is ppa [H]

Identifier: 183220703

GI number: 183220703

Start: 1369755

End: 1370378

Strand: Direct

Name: ppa [H]

Synonym: LEPBI_I1313

Alternate gene names: 183220703

Gene position: 1369755-1370378 (Clockwise)

Preceding gene: 183220702

Following gene: 183220704

Centisome position: 38.05

GC content: 39.9

Gene sequence:

>624_bases
ATGAAACCGAATTATTATGTAGCACACCCTTGGCATGGATTAGAACTAGGACCAAAGGCACCAGATGAACTAGATGTATT
CATTGAGCTCACACCACAAGATACTGTGAAGTATGAGATTGATAAAGCATCTGGTTTCATCCGAGTGGATAGACCACAGA
AATATAGCAATCGTTCTCCGACTTTATATGGATTCATTCCTAGGACATTTTCTGGAGAAGCTTCTGGGAAACATTGTTCG
GAAGTAGTGGGAAGGCCAGATATCCTTGGTGATGGAGACCCAATTGATATTTGTGTATTGAGTGTCAATCCGATCACACA
TGGCAATATGATCCTCACTGTGATACCCATTGGTGGACTTCGGATGATCGATAAGGGTGAGGCCGATGACAAAATTGTCG
CAGTGCTCAAAGGGGATGAAGTGTTTGGGCAAATGAAAGATATTTCTGAAGTTCCAAAGGCTCTTATCAACAAACTCCAT
CATTATTTTCTCACTTATAAATTAGATCCAAACTCTCCATCCACTGGAACAGTCGAAATTACAGAAGTGTATGACAGAGT
GGAAGCAATTAAGGTCATTCAATTTGGAATTGAGGATTATATCAAAAAGTTTGTAACTGTATGA

Upstream 100 bases:

>100_bases
ATCTTCCCATGGTCATGGACATACGCATGACGAAGAAACAAGTTTTCATGAAGAAGATAGAAAACAAACAAAACAAAAAT
CAAAACGTAAGAGGACTTAG

Downstream 100 bases:

>100_bases
AGTATATATTAAGATATCTATTCATCCTTAGTTTGGGTTTCATCACAACGAACATTTCTTCAAAAGAAAAAGCAGTGTAT
GAACTCCATTCTAAAGATGA

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MKPNYYVAHPWHGLELGPKAPDELDVFIELTPQDTVKYEIDKASGFIRVDRPQKYSNRSPTLYGFIPRTFSGEASGKHCS
EVVGRPDILGDGDPIDICVLSVNPITHGNMILTVIPIGGLRMIDKGEADDKIVAVLKGDEVFGQMKDISEVPKALINKLH
HYFLTYKLDPNSPSTGTVEITEVYDRVEAIKVIQFGIEDYIKKFVTV

Sequences:

>Translated_207_residues
MKPNYYVAHPWHGLELGPKAPDELDVFIELTPQDTVKYEIDKASGFIRVDRPQKYSNRSPTLYGFIPRTFSGEASGKHCS
EVVGRPDILGDGDPIDICVLSVNPITHGNMILTVIPIGGLRMIDKGEADDKIVAVLKGDEVFGQMKDISEVPKALINKLH
HYFLTYKLDPNSPSTGTVEITEVYDRVEAIKVIQFGIEDYIKKFVTV
>Mature_207_residues
MKPNYYVAHPWHGLELGPKAPDELDVFIELTPQDTVKYEIDKASGFIRVDRPQKYSNRSPTLYGFIPRTFSGEASGKHCS
EVVGRPDILGDGDPIDICVLSVNPITHGNMILTVIPIGGLRMIDKGEADDKIVAVLKGDEVFGQMKDISEVPKALINKLH
HYFLTYKLDPNSPSTGTVEITEVYDRVEAIKVIQFGIEDYIKKFVTV

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=154, Percent_Identity=33.1168831168831, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 23090; Mature: 23090

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPNYYVAHPWHGLELGPKAPDELDVFIELTPQDTVKYEIDKASGFIRVDRPQKYSNRSP
CCCCEEEECCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCEEEECCCCCCCCCCC
TLYGFIPRTFSGEASGKHCSEVVGRPDILGDGDPIDICVLSVNPITHGNMILTVIPIGGL
EEEEEECCCCCCCCCCCHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEEECCCE
RMIDKGEADDKIVAVLKGDEVFGQMKDISEVPKALINKLHHYFLTYKLDPNSPSTGTVEI
EEEECCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCEEEH
TEVYDRVEAIKVIQFGIEDYIKKFVTV
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKPNYYVAHPWHGLELGPKAPDELDVFIELTPQDTVKYEIDKASGFIRVDRPQKYSNRSP
CCCCEEEECCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCEEEECCCCCCCCCCC
TLYGFIPRTFSGEASGKHCSEVVGRPDILGDGDPIDICVLSVNPITHGNMILTVIPIGGL
EEEEEECCCCCCCCCCCHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEEECCCE
RMIDKGEADDKIVAVLKGDEVFGQMKDISEVPKALINKLHHYFLTYKLDPNSPSTGTVEI
EEEECCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCEEEH
TEVYDRVEAIKVIQFGIEDYIKKFVTV
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]