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The map label for this gene is yciC [H]

Identifier: 183220648

GI number: 183220648

Start: 1301080

End: 1302351

Strand: Reverse

Name: yciC [H]

Synonym: LEPBI_I1256

Alternate gene names: 183220648

Gene position: 1302351-1301080 (Counterclockwise)

Preceding gene: 183220659

Following gene: 183220647

Centisome position: 36.18

GC content: 40.09

Gene sequence:

>1272_bases
TTGCAAAAAGTGGTAAACCCTATGGACAAAAAAATACCCGTCACAGTCTTATCTGGATTTTTAGGTGCTGGCAAAACAAC
CCTACTCAATCACGTTCTTTCCAATCGAGAAGGGCTTCGCGTTGCAGTCATCGTCAATGATATGAGCGATGTGAACATTG
ATGCAAAGTTAGTTGCGAATGGGGGGAAACTCAGCCGGACTAACGAATCTCTCGTCGAAATGTCCAATGGTTGTATCTGC
TGCACCTTAAGAGAAGACCTTCTCATTGAAATCACAAAACTTGCTAAAGAGAATGTATTTGATTTTATTCTGATTGAATC
CACTGGGATCTCTGAACCATTACCCATCGCAGAGACGTTTACCTTTGCAGATGAAAACGGAGTGAGTTTATCTGACCTCG
TGACATTGGATTCAATGATTACCGTTGTGGATGCAGTCAATTTTTTAAATGATTTTGAAAGTTTGGATTCACTGAAAGAA
CGAGAATTAGGTGCTGGAGAAGAAGATGATAGAGATATAGTGGACTTACTTGTAGACCAAGTAGAATTCTCCAACACGTT
GGTCGTCAATAAAATTAGCCTCTTATCAGAATCAAAAAAACAAAAACTCCTTACCATTTTACGTTCCTTAAATGCTCAGG
CAGAAATCATTACAACCGATTATGGACAGGTTCCCTTTGATAAGGTATTCCAAACGGGGAAGTTTGATTTTGAAAAGGCA
AAACAATTTCCCTTATGGCTAAAAGAACTAAGAGGGGAACATATCCCGGAAACAGAAGAATATGGAATCAAAAGTTTCGT
GTATGGTAACAGAAGGCCAATGCATCCAAAACGTTTTTATGAATGGTTAGATTCCGAAAAACCAGGTTTGATCAGAGCAA
AAGGTTTCGTATGGCTTGCCTCCAAAATGGATTGGGTTCTTCTGTATTCACAAGCAGGGAATTTATCTTCTTACAAACCG
GAAGGGTATTGGTGGGCAAGTATCGCTTCAGAAGACATTCCTGATGATCCTGATGTCCAAGAGAATTTAAAACAACATTG
GTTGGAACCGTGGGGAGATCGGAGGCAAGAAATTGTCCTCATCGGTCGGGATCTGAATGAAAAAAAACTAAGGTCTTCAT
TGAATGCATGTTTGTTAACTGAGGATGAAATCAAACAGGGCCCAGAATTTTGGGAAACCTTAGAAGATCCATTTCCCAAT
TGGGATGAGATGATGGAATCCTCTGAACAACTAACAGAATCTGAGTTGGATCCTCTGAGGGTCACGAAATGA

Upstream 100 bases:

>100_bases
GATCCAACTACGATCCCCTTCCCAACTCCGATCGAACATTTTGCAACATTGTTGCATTTGTGATTGACAGAATTAGCCAC
TGCTTTTAAATGCAACTTAA

Downstream 100 bases:

>100_bases
AAGTGTATTTAGGTGACCTGCCAGTGGAACTCATTGGCAAAAGACCAAAAACAGGCGAACCTATCGATGGTAAGTTTGGT
TTTAGACCGGTGCTCAACAC

Product: putative cobalt reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MQKVVNPMDKKIPVTVLSGFLGAGKTTLLNHVLSNREGLRVAVIVNDMSDVNIDAKLVANGGKLSRTNESLVEMSNGCIC
CTLREDLLIEITKLAKENVFDFILIESTGISEPLPIAETFTFADENGVSLSDLVTLDSMITVVDAVNFLNDFESLDSLKE
RELGAGEEDDRDIVDLLVDQVEFSNTLVVNKISLLSESKKQKLLTILRSLNAQAEIITTDYGQVPFDKVFQTGKFDFEKA
KQFPLWLKELRGEHIPETEEYGIKSFVYGNRRPMHPKRFYEWLDSEKPGLIRAKGFVWLASKMDWVLLYSQAGNLSSYKP
EGYWWASIASEDIPDDPDVQENLKQHWLEPWGDRRQEIVLIGRDLNEKKLRSSLNACLLTEDEIKQGPEFWETLEDPFPN
WDEMMESSEQLTESELDPLRVTK

Sequences:

>Translated_423_residues
MQKVVNPMDKKIPVTVLSGFLGAGKTTLLNHVLSNREGLRVAVIVNDMSDVNIDAKLVANGGKLSRTNESLVEMSNGCIC
CTLREDLLIEITKLAKENVFDFILIESTGISEPLPIAETFTFADENGVSLSDLVTLDSMITVVDAVNFLNDFESLDSLKE
RELGAGEEDDRDIVDLLVDQVEFSNTLVVNKISLLSESKKQKLLTILRSLNAQAEIITTDYGQVPFDKVFQTGKFDFEKA
KQFPLWLKELRGEHIPETEEYGIKSFVYGNRRPMHPKRFYEWLDSEKPGLIRAKGFVWLASKMDWVLLYSQAGNLSSYKP
EGYWWASIASEDIPDDPDVQENLKQHWLEPWGDRRQEIVLIGRDLNEKKLRSSLNACLLTEDEIKQGPEFWETLEDPFPN
WDEMMESSEQLTESELDPLRVTK
>Mature_423_residues
MQKVVNPMDKKIPVTVLSGFLGAGKTTLLNHVLSNREGLRVAVIVNDMSDVNIDAKLVANGGKLSRTNESLVEMSNGCIC
CTLREDLLIEITKLAKENVFDFILIESTGISEPLPIAETFTFADENGVSLSDLVTLDSMITVVDAVNFLNDFESLDSLKE
RELGAGEEDDRDIVDLLVDQVEFSNTLVVNKISLLSESKKQKLLTILRSLNAQAEIITTDYGQVPFDKVFQTGKFDFEKA
KQFPLWLKELRGEHIPETEEYGIKSFVYGNRRPMHPKRFYEWLDSEKPGLIRAKGFVWLASKMDWVLLYSQAGNLSSYKP
EGYWWASIASEDIPDDPDVQENLKQHWLEPWGDRRQEIVLIGRDLNEKKLRSSLNACLLTEDEIKQGPEFWETLEDPFPN
WDEMMESSEQLTESELDPLRVTK

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI126722884, Length=319, Percent_Identity=31.0344827586207, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI33469141, Length=319, Percent_Identity=30.7210031347962, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI146231952, Length=319, Percent_Identity=31.3479623824451, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI148727351, Length=319, Percent_Identity=31.0344827586207, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI223941779, Length=319, Percent_Identity=30.0940438871473, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI223941776, Length=305, Percent_Identity=30.1639344262295, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI119120938, Length=141, Percent_Identity=41.1347517730496, Blast_Score=98, Evalue=2e-20,
Organism=Escherichia coli, GI87082430, Length=379, Percent_Identity=27.9683377308707, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788499, Length=210, Percent_Identity=25.7142857142857, Blast_Score=69, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6324356, Length=234, Percent_Identity=27.7777777777778, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 48090; Mature: 48090

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKVVNPMDKKIPVTVLSGFLGAGKTTLLNHVLSNREGLRVAVIVNDMSDVNIDAKLVAN
CCCCCCCHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEEEEC
GGKLSRTNESLVEMSNGCICCTLREDLLIEITKLAKENVFDFILIESTGISEPLPIAETF
CCCCCCCCHHHHHHCCCEEEEEECHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCHHEE
TFADENGVSLSDLVTLDSMITVVDAVNFLNDFESLDSLKERELGAGEEDDRDIVDLLVDQ
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
VEFSNTLVVNKISLLSESKKQKLLTILRSLNAQAEIITTDYGQVPFDKVFQTGKFDFEKA
HHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCCCCHHHH
KQFPLWLKELRGEHIPETEEYGIKSFVYGNRRPMHPKRFYEWLDSEKPGLIRAKGFVWLA
HCCHHHHHHHCCCCCCCHHHHCCHHHCCCCCCCCCHHHHHHHHCCCCCCEEEECCEEEEE
SKMDWVLLYSQAGNLSSYKPEGYWWASIASEDIPDDPDVQENLKQHWLEPWGDRRQEIVL
CCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEE
IGRDLNEKKLRSSLNACLLTEDEIKQGPEFWETLEDPFPNWDEMMESSEQLTESELDPLR
EECCCCHHHHHHHHHEEEEEHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCC
VTK
CCC
>Mature Secondary Structure
MQKVVNPMDKKIPVTVLSGFLGAGKTTLLNHVLSNREGLRVAVIVNDMSDVNIDAKLVAN
CCCCCCCHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEEEEC
GGKLSRTNESLVEMSNGCICCTLREDLLIEITKLAKENVFDFILIESTGISEPLPIAETF
CCCCCCCCHHHHHHCCCEEEEEECHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCHHEE
TFADENGVSLSDLVTLDSMITVVDAVNFLNDFESLDSLKERELGAGEEDDRDIVDLLVDQ
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
VEFSNTLVVNKISLLSESKKQKLLTILRSLNAQAEIITTDYGQVPFDKVFQTGKFDFEKA
HHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCCCCHHHH
KQFPLWLKELRGEHIPETEEYGIKSFVYGNRRPMHPKRFYEWLDSEKPGLIRAKGFVWLA
HCCHHHHHHHCCCCCCCHHHHCCHHHCCCCCCCCCHHHHHHHHCCCCCCEEEECCEEEEE
SKMDWVLLYSQAGNLSSYKPEGYWWASIASEDIPDDPDVQENLKQHWLEPWGDRRQEIVL
CCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEE
IGRDLNEKKLRSSLNACLLTEDEIKQGPEFWETLEDPFPNWDEMMESSEQLTESELDPLR
EECCCCHHHHHHHHHEEEEEHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCC
VTK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]