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The map label for this gene is xylB [H]

Identifier: 183220157

GI number: 183220157

Start: 761386

End: 762984

Strand: Direct

Name: xylB [H]

Synonym: LEPBI_I0745

Alternate gene names: 183220157

Gene position: 761386-762984 (Clockwise)

Preceding gene: 183220155

Following gene: 183220158

Centisome position: 21.15

GC content: 40.34

Gene sequence:

>1599_bases
ATGGATACAGACTGCATTTTGGCCTATGATATTGGCACCACGGGAGTCAAAACATGCCTTTTCCGTGTGAATTCCACTCT
TGAATTGCTCGCATCTGCCACAAAGGAATACCCCATCCAACTCCTTGCAAACGGGGGAGCAGAACAGAATCCAGAGGATT
GGTGGTTGGCAATGCAATCTACCACTGCAACCGTATTAAGCGATGCAAAGATGAACAAAGATCGGATCCAAGGGATTTCG
TTTTGTTCTCAGATGCAAGGATTAGTCCTTGTTGATGAAAATTTTGATCCAGTTCGAAATGCAATGAGTTATATGGACCA
AAGGGCCAGTTCGGAAATGAAAAAAGGAATCAGCCATGGATTCAAAATTGAAGGGATTAATGCCATTAAACTATTGTTAT
CTCTTTGGATCACCGGTGCAGTTGCTGCGAGTGTAAAAGATCCTATCTGGAAATACAAATGGGTAGAAAAGAACGAACCA
GAAAACTTTGGTAAGGTGAGGTGGTGGTTTGATGTCAAAGAATATTTAATCGCTAGGTGTACAAACGAGGCGGTCATGAC
TCGGGATTCTGCATTTGCAACTTTTTTATACAACTCTAGAAAAGGAAAGGGCGATTGGAGTCCTCTCCTTTGTAAATTGT
TTGGAGTTCGTAGGGAACATTTGCCAAAAATCATTAACGCAGAAGAAAAAGTTGGCGGATTAACAAGAGAAGCCGCTGAA
TTTTTGGGATTAAAGACCGATACACTCGTGTTTGGTGGTGGGGGAGATGCCTCTCTCATTGGAGTTGGCGCGGGTGCAGT
AGAAGAAGGAGATACACATATCTATGCCGGTACTTCTGGTTGGATTGGTACTGTTACCAAAAAAAGAACTGTCGATATTG
ATGCGAGAATCGCTTCCATTGTAGGTGCAAGAGATGGGTATTATAATTATTTTGGGGAACAAGAAACATCAGGTAAATGT
TTACAATGGGTAAAAGACCATTTGGCATTGGATGAAATTGATTTATATTTAGAAAAAAAGAAAATCACAGATGGACCTGA
CGCTATCTATGAAAGTTTGTTTGAGTTTATGTTTGATTCCATCAAAGACACAGAACCAGGATCGCATGGTGTCATCTTTA
CACCTTGGTTACATGGGAATCGTTGTCCATTTGAAGATCCAAAAGCAAGAGGGATCTTTTTTAATATCAGTTTACATACT
GGTAAACGAGTGTTGATCCGTGCTGTGATTGAAGGGATTTTATTTCACAAACGTTGGATTTTGGAATTGTCTGATCGGAA
AGTAAAAACATCCAACAAGATTCGATTTGTGGGTGGTGTGGCAAGGTCTAGTTTTATTTGTCAAATGTTAGCTGATATAA
CAGGTAAAACGATCGAAAGGGTTATCCACCCAGAAAACGTGGGTGCCATTGGTGCTGCCGCCATCGCCGCACTAGGACTC
GGCAAAATCAAGGAGTTCGAAGACATCAAACAAATGATCCCTGTGGATCAAACATGGACACCTAACACTTTTCTAAAACC
TGTATACGATAAAAACTTTTCTGTGTTTCAGAATCTATACGAATCAAACAAAAAACATTTTGCGATGTTAAATTCTTAA

Upstream 100 bases:

>100_bases
ACTTTTTTCTCTTTGGCGTAGAAAATTACCAGATTTTTCCCAAATGGAAGGATTAAGCGTAACATTAGGGGGAAACGGTC
CCCGAAACGAAGGAGTTTCC

Downstream 100 bases:

>100_bases
ATTGAAGAAGGTAAAAAATGAATTTATATACTGAGTTAACGTATGAAAAATTGGGTAATCCTTTTGCCATCGGTCGGTCG
GCTGATTTGTATCTACTTCC

Product: putative xylulokinase

Products: ADP; D-xylulose 5-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 532; Mature: 532

Protein sequence:

>532_residues
MDTDCILAYDIGTTGVKTCLFRVNSTLELLASATKEYPIQLLANGGAEQNPEDWWLAMQSTTATVLSDAKMNKDRIQGIS
FCSQMQGLVLVDENFDPVRNAMSYMDQRASSEMKKGISHGFKIEGINAIKLLLSLWITGAVAASVKDPIWKYKWVEKNEP
ENFGKVRWWFDVKEYLIARCTNEAVMTRDSAFATFLYNSRKGKGDWSPLLCKLFGVRREHLPKIINAEEKVGGLTREAAE
FLGLKTDTLVFGGGGDASLIGVGAGAVEEGDTHIYAGTSGWIGTVTKKRTVDIDARIASIVGARDGYYNYFGEQETSGKC
LQWVKDHLALDEIDLYLEKKKITDGPDAIYESLFEFMFDSIKDTEPGSHGVIFTPWLHGNRCPFEDPKARGIFFNISLHT
GKRVLIRAVIEGILFHKRWILELSDRKVKTSNKIRFVGGVARSSFICQMLADITGKTIERVIHPENVGAIGAAAIAALGL
GKIKEFEDIKQMIPVDQTWTPNTFLKPVYDKNFSVFQNLYESNKKHFAMLNS

Sequences:

>Translated_532_residues
MDTDCILAYDIGTTGVKTCLFRVNSTLELLASATKEYPIQLLANGGAEQNPEDWWLAMQSTTATVLSDAKMNKDRIQGIS
FCSQMQGLVLVDENFDPVRNAMSYMDQRASSEMKKGISHGFKIEGINAIKLLLSLWITGAVAASVKDPIWKYKWVEKNEP
ENFGKVRWWFDVKEYLIARCTNEAVMTRDSAFATFLYNSRKGKGDWSPLLCKLFGVRREHLPKIINAEEKVGGLTREAAE
FLGLKTDTLVFGGGGDASLIGVGAGAVEEGDTHIYAGTSGWIGTVTKKRTVDIDARIASIVGARDGYYNYFGEQETSGKC
LQWVKDHLALDEIDLYLEKKKITDGPDAIYESLFEFMFDSIKDTEPGSHGVIFTPWLHGNRCPFEDPKARGIFFNISLHT
GKRVLIRAVIEGILFHKRWILELSDRKVKTSNKIRFVGGVARSSFICQMLADITGKTIERVIHPENVGAIGAAAIAALGL
GKIKEFEDIKQMIPVDQTWTPNTFLKPVYDKNFSVFQNLYESNKKHFAMLNS
>Mature_532_residues
MDTDCILAYDIGTTGVKTCLFRVNSTLELLASATKEYPIQLLANGGAEQNPEDWWLAMQSTTATVLSDAKMNKDRIQGIS
FCSQMQGLVLVDENFDPVRNAMSYMDQRASSEMKKGISHGFKIEGINAIKLLLSLWITGAVAASVKDPIWKYKWVEKNEP
ENFGKVRWWFDVKEYLIARCTNEAVMTRDSAFATFLYNSRKGKGDWSPLLCKLFGVRREHLPKIINAEEKVGGLTREAAE
FLGLKTDTLVFGGGGDASLIGVGAGAVEEGDTHIYAGTSGWIGTVTKKRTVDIDARIASIVGARDGYYNYFGEQETSGKC
LQWVKDHLALDEIDLYLEKKKITDGPDAIYESLFEFMFDSIKDTEPGSHGVIFTPWLHGNRCPFEDPKARGIFFNISLHT
GKRVLIRAVIEGILFHKRWILELSDRKVKTSNKIRFVGGVARSSFICQMLADITGKTIERVIHPENVGAIGAAAIAALGL
GKIKEFEDIKQMIPVDQTWTPNTFLKPVYDKNFSVFQNLYESNKKHFAMLNS

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI164663828, Length=564, Percent_Identity=25.886524822695, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI164663830, Length=588, Percent_Identity=25.5102040816327, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI42794763, Length=476, Percent_Identity=22.8991596638655, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI189409120, Length=476, Percent_Identity=23.109243697479, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI4504007, Length=476, Percent_Identity=23.109243697479, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI88196792, Length=527, Percent_Identity=20.1138519924099, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI41393575, Length=472, Percent_Identity=22.0338983050847, Blast_Score=79, Evalue=9e-15,
Organism=Escherichia coli, GI1789987, Length=521, Percent_Identity=25.1439539347409, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1790005, Length=488, Percent_Identity=25.2049180327869, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI1790361, Length=508, Percent_Identity=23.6220472440945, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1787789, Length=540, Percent_Identity=22.5925925925926, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1789168, Length=505, Percent_Identity=20.7920792079208, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786249, Length=329, Percent_Identity=22.1884498480243, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71986140, Length=245, Percent_Identity=26.9387755102041, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71986147, Length=245, Percent_Identity=26.9387755102041, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24656367, Length=511, Percent_Identity=21.3307240704501, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI21357867, Length=523, Percent_Identity=21.0325047801147, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24657106, Length=566, Percent_Identity=24.2049469964664, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24657102, Length=566, Percent_Identity=24.2049469964664, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24656372, Length=323, Percent_Identity=23.5294117647059, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21356323, Length=463, Percent_Identity=25.0539956803456, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17864214, Length=539, Percent_Identity=22.8200371057514, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24654573, Length=466, Percent_Identity=22.7467811158798, Blast_Score=74, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: 2.7.1.17

Molecular weight: Translated: 59424; Mature: 59424

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTDCILAYDIGTTGVKTCLFRVNSTLELLASATKEYPIQLLANGGAEQNPEDWWLAMQS
CCCCEEEEEECCCHHHHHHHHHHCHHHHHHHHHHHCCCEEEEECCCCCCCCCHHEEEEEC
TTATVLSDAKMNKDRIQGISFCSQMQGLVLVDENFDPVRNAMSYMDQRASSEMKKGISHG
CHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCC
FKIEGINAIKLLLSLWITGAVAASVKDPIWKYKWVEKNEPENFGKVRWWFDVKEYLIARC
CEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEEEEHHHHHHHHC
TNEAVMTRDSAFATFLYNSRKGKGDWSPLLCKLFGVRREHLPKIINAEEKVGGLTREAAE
CCCHHEECCCHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHH
FLGLKTDTLVFGGGGDASLIGVGAGAVEEGDTHIYAGTSGWIGTVTKKRTVDIDARIASI
HHCCCCCEEEEECCCCCEEEEECCCCCCCCCCEEEECCCCCEECCCCCEEEEHHHHHHHH
VGARDGYYNYFGEQETSGKCLQWVKDHLALDEIDLYLEKKKITDGPDAIYESLFEFMFDS
HCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHH
IKDTEPGSHGVIFTPWLHGNRCPFEDPKARGIFFNISLHTGKRVLIRAVIEGILFHKRWI
HCCCCCCCCCEEECCEECCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHE
LELSDRKVKTSNKIRFVGGVARSSFICQMLADITGKTIERVIHPENVGAIGAAAIAALGL
EEECCCEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
GKIKEFEDIKQMIPVDQTWTPNTFLKPVYDKNFSVFQNLYESNKKHFAMLNS
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCHHHHHHHHHCCCCEEEEECC
>Mature Secondary Structure
MDTDCILAYDIGTTGVKTCLFRVNSTLELLASATKEYPIQLLANGGAEQNPEDWWLAMQS
CCCCEEEEEECCCHHHHHHHHHHCHHHHHHHHHHHCCCEEEEECCCCCCCCCHHEEEEEC
TTATVLSDAKMNKDRIQGISFCSQMQGLVLVDENFDPVRNAMSYMDQRASSEMKKGISHG
CHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCC
FKIEGINAIKLLLSLWITGAVAASVKDPIWKYKWVEKNEPENFGKVRWWFDVKEYLIARC
CEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEEEEHHHHHHHHC
TNEAVMTRDSAFATFLYNSRKGKGDWSPLLCKLFGVRREHLPKIINAEEKVGGLTREAAE
CCCHHEECCCHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHH
FLGLKTDTLVFGGGGDASLIGVGAGAVEEGDTHIYAGTSGWIGTVTKKRTVDIDARIASI
HHCCCCCEEEEECCCCCEEEEECCCCCCCCCCEEEECCCCCEECCCCCEEEEHHHHHHHH
VGARDGYYNYFGEQETSGKCLQWVKDHLALDEIDLYLEKKKITDGPDAIYESLFEFMFDS
HCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHH
IKDTEPGSHGVIFTPWLHGNRCPFEDPKARGIFFNISLHTGKRVLIRAVIEGILFHKRWI
HCCCCCCCCCEEECCEECCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHE
LELSDRKVKTSNKIRFVGGVARSSFICQMLADITGKTIERVIHPENVGAIGAAAIAALGL
EEECCCEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
GKIKEFEDIKQMIPVDQTWTPNTFLKPVYDKNFSVFQNLYESNKKHFAMLNS
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCHHHHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-xylulose

Specific reaction: ATP + D-xylulose = ADP + D-xylulose 5-phosphate

General reaction: Phospho group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA