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The map label for this gene is dapB [H]

Identifier: 183220146

GI number: 183220146

Start: 748830

End: 749633

Strand: Direct

Name: dapB [H]

Synonym: LEPBI_I0734

Alternate gene names: 183220146

Gene position: 748830-749633 (Clockwise)

Preceding gene: 183220145

Following gene: 183220147

Centisome position: 20.8

GC content: 41.42

Gene sequence:

>804_bases
TTGTCTAAAATCAAAGTAGGTGTGATAGGGGCTGGAGGAAGGATGGGGAAAGCCATCATCCAAGTACTTTCCCTTTCCAA
AAAATCAGAGTTAAGCGCTGCTGTTGTGAGAGAAGGCGCCATTTATGCTGGATTTGATTCTGGAAATCATGCTGGAATCA
AAGAAACGGGTATCTTACTTTCATCCGACTTACAGAAAGCATGTGAAGGATCCGATGTCCTCATTGATTTTAGTACTCAT
ACAGGTTTTGAATCAATATTAAATGCGGCATTACAAAATCACAAACCATTGGTCATCGGAACGACAGGTCTTACTGATTC
AGACAAAACATTAATCCAATCGGCCGCAAAAACCATTCCGATTGTTTTTTCTCCCAATATGTCTGTTGGTGTGAACTTAC
TATTTAAACTCACCGAAATTGCCGCAAAAGTCCTTCACGAAGATTTTGATATTGAAGTTTTGGACATCCACCATCGCCAC
AAAAAAGATGCTCCATCGGGTACAGCCATGTACCTAAAAGAAGTGTTGCTTGGGGCAAGCAAACGAAGTGAAGAGAATGT
GATTTATGGTCGCCATGGGATGTATCCAGAACGTGACCAAAAGGAAATTGCGATGCACACTATGCGTGCAGGTGAAGTGG
TTGGGGAACACACCGTTTATTTTTTTAGTCCTGAAGAAAGGATAGAGATCACACACCGTGCACAGGACCGCAAAACATTT
GCTAGTGGTGCAGTCAAAGCTGCCGAATTTTTACATGGCAAATCGAAAGGTTTGTACAATATGTTTGATGTTTTAGGGAT
TTAA

Upstream 100 bases:

>100_bases
TATTGTAGTAACGAACTCAGATTACCGATGACTTCTTTATCTGAAGGTACAGCATCAGAGTCGTTCAAAAAAATTGTATT
CCAACTAAAAGAGGAAGGCA

Downstream 100 bases:

>100_bases
ATTGGATTTTTTTCGAGGATTATACATCATTCCGTGGAGTAAAAATTATATCTCCATTACACTTGATGTACTCATCGTCG
CGTTTCTGATTTATAAAACA

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR [H]

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MSKIKVGVIGAGGRMGKAIIQVLSLSKKSELSAAVVREGAIYAGFDSGNHAGIKETGILLSSDLQKACEGSDVLIDFSTH
TGFESILNAALQNHKPLVIGTTGLTDSDKTLIQSAAKTIPIVFSPNMSVGVNLLFKLTEIAAKVLHEDFDIEVLDIHHRH
KKDAPSGTAMYLKEVLLGASKRSEENVIYGRHGMYPERDQKEIAMHTMRAGEVVGEHTVYFFSPEERIEITHRAQDRKTF
ASGAVKAAEFLHGKSKGLYNMFDVLGI

Sequences:

>Translated_267_residues
MSKIKVGVIGAGGRMGKAIIQVLSLSKKSELSAAVVREGAIYAGFDSGNHAGIKETGILLSSDLQKACEGSDVLIDFSTH
TGFESILNAALQNHKPLVIGTTGLTDSDKTLIQSAAKTIPIVFSPNMSVGVNLLFKLTEIAAKVLHEDFDIEVLDIHHRH
KKDAPSGTAMYLKEVLLGASKRSEENVIYGRHGMYPERDQKEIAMHTMRAGEVVGEHTVYFFSPEERIEITHRAQDRKTF
ASGAVKAAEFLHGKSKGLYNMFDVLGI
>Mature_266_residues
SKIKVGVIGAGGRMGKAIIQVLSLSKKSELSAAVVREGAIYAGFDSGNHAGIKETGILLSSDLQKACEGSDVLIDFSTHT
GFESILNAALQNHKPLVIGTTGLTDSDKTLIQSAAKTIPIVFSPNMSVGVNLLFKLTEIAAKVLHEDFDIEVLDIHHRHK
KDAPSGTAMYLKEVLLGASKRSEENVIYGRHGMYPERDQKEIAMHTMRAGEVVGEHTVYFFSPEERIEITHRAQDRKTFA
SGAVKAAEFLHGKSKGLYNMFDVLGI

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786214, Length=265, Percent_Identity=45.2830188679245, Blast_Score=204, Evalue=6e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040 [H]

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N [H]

EC number: =1.3.1.26 [H]

Molecular weight: Translated: 29007; Mature: 28875

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIKVGVIGAGGRMGKAIIQVLSLSKKSELSAAVVREGAIYAGFDSGNHAGIKETGILL
CCCEEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCCCCCCHHHCEEE
SSDLQKACEGSDVLIDFSTHTGFESILNAALQNHKPLVIGTTGLTDSDKTLIQSAAKTIP
HHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHEE
IVFSPNMSVGVNLLFKLTEIAAKVLHEDFDIEVLDIHHRHKKDAPSGTAMYLKEVLLGAS
EEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHCCCCCCCCHHHHHHHHHHCCC
KRSEENVIYGRHGMYPERDQKEIAMHTMRAGEVVGEHTVYFFSPEERIEITHRAQDRKTF
CCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCEECCCEEEEECCHHHEEEEHHHHHHHHH
ASGAVKAAEFLHGKSKGLYNMFDVLGI
HHHHHHHHHHHHCCCCCHHHHHHHHCC
>Mature Secondary Structure 
SKIKVGVIGAGGRMGKAIIQVLSLSKKSELSAAVVREGAIYAGFDSGNHAGIKETGILL
CCEEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCCCCCCHHHCEEE
SSDLQKACEGSDVLIDFSTHTGFESILNAALQNHKPLVIGTTGLTDSDKTLIQSAAKTIP
HHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHEE
IVFSPNMSVGVNLLFKLTEIAAKVLHEDFDIEVLDIHHRHKKDAPSGTAMYLKEVLLGAS
EEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHCCCCCCCCHHHHHHHHHHCCC
KRSEENVIYGRHGMYPERDQKEIAMHTMRAGEVVGEHTVYFFSPEERIEITHRAQDRKTF
CCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCEECCCEEEEECCHHHEEEEHHHHHHHHH
ASGAVKAAEFLHGKSKGLYNMFDVLGI
HHHHHHHHHHHHCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA