| Definition | Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)' chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_010602 |
| Length | 3,599,677 |
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The map label for this gene is mrcA [H]
Identifier: 183220050
GI number: 183220050
Start: 641764
End: 644346
Strand: Direct
Name: mrcA [H]
Synonym: LEPBI_I0637
Alternate gene names: 183220050
Gene position: 641764-644346 (Clockwise)
Preceding gene: 183220049
Following gene: 183220051
Centisome position: 17.83
GC content: 41.5
Gene sequence:
>2583_bases ATGTCGGCACCGTCTCTTAAATACCTTTGTCCTCACTGCCAGAAAGCATCTCGTTTGCCAGAACCAACTCCGAAAGAAGG AAAATTCCAGCTAACGTGTGCTCACTGTTCCGAGAAGGTAGTTTTACAGTTTATTGACTATCGATTTGAGATTGTCCAAG TTTTGCCGAGTGCCATCGATGAATCCAAACAATCCTACCAAAGTTTTAAGATTCCAGTTCCAGGCATTTCCGCACAATCG AAAGAGAATTTTCCTTCCCGTTCCCCTTCCAAACCTTTCTTTGAAAAAAAAATAATCTGGGAAAAAGAATCGAAGAAACC AAATCCAAAACCGTTTGCTTTTTCGAAACGGATTCCTGTTTTGAAAAAAGATCCCAGTAAATTTTCCTATTGGAAAGTTG GGTTTACCATCACCTCGATCACTTTGTTTTTATTCATTGTTAGTTTTTCCTATTTTGTTGCGGGTGTCCTTGTTACCAAA AAGGAAGTTCCTCTCTATTTGGAATCTTTGTCAAAAAATATTCCCACAAAAATCTTGGATCGAAATGGACAGGTAGTGAG TGAGATTTTCCAAAAACGTACTTCCACCTTACATTTGCAAGACTATCCAGAAGATATGATCTCCATTTTGCTTAATATTG AAGATCAAAAGTTTTTTTTCCATGGTGGGATTGATTATTCTGCCATACTACGAGCCTTTTTTAAAAACATTGTGAATTTG AGTTACAAACAAGGTGCGTCGACCATCACCCAACAGTTAGCAAGGATTATCTTGGATGACCGTCGCAAAAGTTTGAATCG AAAATGGAGGGAAGCACAACTTGCCTTTGCTCTTGAATCCGTTTTAACCAAAGAACAAATCCTTGAGACCTATATGAACC ATGTGTATTTGGGCCATGGTGCCTTTGGATTTGGAGAAGGGATCAAGTTTTATTTTCAGAAAAATCCTATGGAGTTATCC AAAGAAGAAATGGTGTTACTCGCTTCTTTGCCATCCGCTCCTAACAAGTATTCACCGTTAAAAAACCCTGAGGATTCATA TACTCGTGTTCGTGCCATATTAAATATGTTTCGTAACCGTGGGATTTATCCGAATTTGGATCGGGATAAGTTGATTGGTT TGTATCACAATTTATCGACACGTTCTCCAAATGAAACTGTCTTCGGTTCAAGGCATGACATCGCACCATATGTAACAGAA CATGTTCGCTCGGTACTTTCATCACTCGAAGGGGAAAAAAATATTTATGAAAGTGGTGGGTATACAGTGGAAACCACTTT GGATCGAAATGCCCAAGAAGTAATCGGTCCAATCGTCAGGGAATATTTAGCCAAAAACAAACGTTCTGGCAAAATCCAAA AACGACGGATTCGATTAAAACCAGAGTCACCATTGGATCTTGCCTTTCGCCAAAAGATGGAAGAAGTTTCTCTTCTTAAT GAATTTGTTTGGAATCCAGACCAATTGGAATCAGATAAAGACCAAAGTATCGTCCAGGCGGCCATTGTGGGGATTCAACC TAACACTGGACAGGTGCTGTTTTTGCATGGTGGGGATGAATTTAATTCACAAAACCAGTTCAATCGTGCCACTCAGATGC GTAGGCAGACAGGAAGCTCCATTAAAGCTGTGTTATATGCTTCCGCAATTGATTCAGGGTCCATCCATGCTGGTATGAAA ATCCTAGATGCTCCTTTGTATTACCGTGGAGGTGGGGGAAAGGAATGGGCTCCGGAGAATTTAGGTGGGAGTTTTGATGG AGAGATCTCTCTACGCACTGCCCTTGTGAAATCTAAAAACACAGCAGCCGTACAAGTCGCAGAGCGACTTGGGAGTGCGG GCATTGAAAAGTATTTTACGAAGTTCTTTTTTCCAAATGATGCTGAGAAAAAAAATCGATACCGTGGTGACCTTTCCTTG GCATTGGGAACACTTGAAATTTCACCACTGGAAATGGCTTCTGCCTTCACTAGTTTTGTGAACCAGGGGAATGTCAAACG ACCATACCTCATCCAAAGGATTAAAAATGCCAAAGGAAATGTATTGTATGAAGTTGGTGCCAGTGATGAGTTCAAATTAA AATTACCAGAAGAACGCCAAGTGATTCGGCCTGACACGGCTGAAGTGATGGTGTCATTACTTCGAGATAGTGGAAGGGCG AGTGGTGTACGGAACGGCGGTTATACGGGAGATCTCATCGGTAAAACAGGTACCACCAATGATTATAAAGATGCATGGTT TGTGGGTGCACGGCCAGATCTATCGCTTGCCGTTTGGGTGGGGTATGATAACCCAAAATTTGGAATGGGACCGAGTGGAC TCGGCGGAGCGGTCGCGGCTCCTCTTTGGGGAGAGATCCTAGCGACCATCGACAAAAAAAGTATCCTTCCCAAAATCCAA TTTAGTTTGCCTGTCTATGCCAAAGCATATAAAATTTGTACCTTAACAGGCAAACAGGCTTCCCCCACATGTCCGAGTAC TCAAGAATTGTATTTATCCGATTATCCACCAGAAGGTCCTTGTAATGATGATCATAAATCGACATCCTCAGATCACAAAG ATTTAATGAAGGGTTTGTATTAA
Upstream 100 bases:
>100_bases TCTCTCTGGATTTCAAAAAGGAAGGGAATCGGCCGAAGATTTTGTGAAAATCGCTGATTTTGTAATTTTAACAAATGACC GATAAGAGTAGGGAGAACCT
Downstream 100 bases:
>100_bases TTGAATTCCTTACGAAGTAATTTTCCAAATACCACCAACTTATTACTGTTTGCCTGTATCCTTTTACTCGTTGGAGTCTT GCAACCAATCAATGCGAGTG
Product: penicillin-binding protein
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 860; Mature: 859
Protein sequence:
>860_residues MSAPSLKYLCPHCQKASRLPEPTPKEGKFQLTCAHCSEKVVLQFIDYRFEIVQVLPSAIDESKQSYQSFKIPVPGISAQS KENFPSRSPSKPFFEKKIIWEKESKKPNPKPFAFSKRIPVLKKDPSKFSYWKVGFTITSITLFLFIVSFSYFVAGVLVTK KEVPLYLESLSKNIPTKILDRNGQVVSEIFQKRTSTLHLQDYPEDMISILLNIEDQKFFFHGGIDYSAILRAFFKNIVNL SYKQGASTITQQLARIILDDRRKSLNRKWREAQLAFALESVLTKEQILETYMNHVYLGHGAFGFGEGIKFYFQKNPMELS KEEMVLLASLPSAPNKYSPLKNPEDSYTRVRAILNMFRNRGIYPNLDRDKLIGLYHNLSTRSPNETVFGSRHDIAPYVTE HVRSVLSSLEGEKNIYESGGYTVETTLDRNAQEVIGPIVREYLAKNKRSGKIQKRRIRLKPESPLDLAFRQKMEEVSLLN EFVWNPDQLESDKDQSIVQAAIVGIQPNTGQVLFLHGGDEFNSQNQFNRATQMRRQTGSSIKAVLYASAIDSGSIHAGMK ILDAPLYYRGGGGKEWAPENLGGSFDGEISLRTALVKSKNTAAVQVAERLGSAGIEKYFTKFFFPNDAEKKNRYRGDLSL ALGTLEISPLEMASAFTSFVNQGNVKRPYLIQRIKNAKGNVLYEVGASDEFKLKLPEERQVIRPDTAEVMVSLLRDSGRA SGVRNGGYTGDLIGKTGTTNDYKDAWFVGARPDLSLAVWVGYDNPKFGMGPSGLGGAVAAPLWGEILATIDKKSILPKIQ FSLPVYAKAYKICTLTGKQASPTCPSTQELYLSDYPPEGPCNDDHKSTSSDHKDLMKGLY
Sequences:
>Translated_860_residues MSAPSLKYLCPHCQKASRLPEPTPKEGKFQLTCAHCSEKVVLQFIDYRFEIVQVLPSAIDESKQSYQSFKIPVPGISAQS KENFPSRSPSKPFFEKKIIWEKESKKPNPKPFAFSKRIPVLKKDPSKFSYWKVGFTITSITLFLFIVSFSYFVAGVLVTK KEVPLYLESLSKNIPTKILDRNGQVVSEIFQKRTSTLHLQDYPEDMISILLNIEDQKFFFHGGIDYSAILRAFFKNIVNL SYKQGASTITQQLARIILDDRRKSLNRKWREAQLAFALESVLTKEQILETYMNHVYLGHGAFGFGEGIKFYFQKNPMELS KEEMVLLASLPSAPNKYSPLKNPEDSYTRVRAILNMFRNRGIYPNLDRDKLIGLYHNLSTRSPNETVFGSRHDIAPYVTE HVRSVLSSLEGEKNIYESGGYTVETTLDRNAQEVIGPIVREYLAKNKRSGKIQKRRIRLKPESPLDLAFRQKMEEVSLLN EFVWNPDQLESDKDQSIVQAAIVGIQPNTGQVLFLHGGDEFNSQNQFNRATQMRRQTGSSIKAVLYASAIDSGSIHAGMK ILDAPLYYRGGGGKEWAPENLGGSFDGEISLRTALVKSKNTAAVQVAERLGSAGIEKYFTKFFFPNDAEKKNRYRGDLSL ALGTLEISPLEMASAFTSFVNQGNVKRPYLIQRIKNAKGNVLYEVGASDEFKLKLPEERQVIRPDTAEVMVSLLRDSGRA SGVRNGGYTGDLIGKTGTTNDYKDAWFVGARPDLSLAVWVGYDNPKFGMGPSGLGGAVAAPLWGEILATIDKKSILPKIQ FSLPVYAKAYKICTLTGKQASPTCPSTQELYLSDYPPEGPCNDDHKSTSSDHKDLMKGLY >Mature_859_residues SAPSLKYLCPHCQKASRLPEPTPKEGKFQLTCAHCSEKVVLQFIDYRFEIVQVLPSAIDESKQSYQSFKIPVPGISAQSK ENFPSRSPSKPFFEKKIIWEKESKKPNPKPFAFSKRIPVLKKDPSKFSYWKVGFTITSITLFLFIVSFSYFVAGVLVTKK EVPLYLESLSKNIPTKILDRNGQVVSEIFQKRTSTLHLQDYPEDMISILLNIEDQKFFFHGGIDYSAILRAFFKNIVNLS YKQGASTITQQLARIILDDRRKSLNRKWREAQLAFALESVLTKEQILETYMNHVYLGHGAFGFGEGIKFYFQKNPMELSK EEMVLLASLPSAPNKYSPLKNPEDSYTRVRAILNMFRNRGIYPNLDRDKLIGLYHNLSTRSPNETVFGSRHDIAPYVTEH VRSVLSSLEGEKNIYESGGYTVETTLDRNAQEVIGPIVREYLAKNKRSGKIQKRRIRLKPESPLDLAFRQKMEEVSLLNE FVWNPDQLESDKDQSIVQAAIVGIQPNTGQVLFLHGGDEFNSQNQFNRATQMRRQTGSSIKAVLYASAIDSGSIHAGMKI LDAPLYYRGGGGKEWAPENLGGSFDGEISLRTALVKSKNTAAVQVAERLGSAGIEKYFTKFFFPNDAEKKNRYRGDLSLA LGTLEISPLEMASAFTSFVNQGNVKRPYLIQRIKNAKGNVLYEVGASDEFKLKLPEERQVIRPDTAEVMVSLLRDSGRAS GVRNGGYTGDLIGKTGTTNDYKDAWFVGARPDLSLAVWVGYDNPKFGMGPSGLGGAVAAPLWGEILATIDKKSILPKIQF SLPVYAKAYKICTLTGKQASPTCPSTQELYLSDYPPEGPCNDDHKSTSSDHKDLMKGLY
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1786343, Length=587, Percent_Identity=27.5979557069847, Blast_Score=170, Evalue=3e-43, Organism=Escherichia coli, GI87082258, Length=274, Percent_Identity=33.2116788321168, Blast_Score=148, Evalue=1e-36, Organism=Escherichia coli, GI1788867, Length=586, Percent_Identity=25.4266211604096, Blast_Score=139, Evalue=8e-34, Organism=Escherichia coli, GI1789601, Length=164, Percent_Identity=33.5365853658537, Blast_Score=76, Evalue=7e-15,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 3.4.-.-
Molecular weight: Translated: 96515; Mature: 96384
Theoretical pI: Translated: 9.67; Mature: 9.67
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.4 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSAPSLKYLCPHCQKASRLPEPTPKEGKFQLTCAHCSEKVVLQFIDYRFEIVQVLPSAID CCCCCCCHHCCCHHHHHCCCCCCCCCCCEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHH ESKQSYQSFKIPVPGISAQSKENFPSRSPSKPFFEKKIIWEKESKKPNPKPFAFSKRIPV HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHEECCCCCCCCCCCCCCCCCCCC LKKDPSKFSYWKVGFTITSITLFLFIVSFSYFVAGVLVTKKEVPLYLESLSKNIPTKILD CCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHC RNGQVVSEIFQKRTSTLHLQDYPEDMISILLNIEDQKFFFHGGIDYSAILRAFFKNIVNL CCCHHHHHHHHHHHCEEEECCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCC SYKQGASTITQQLARIILDDRRKSLNRKWREAQLAFALESVLTKEQILETYMNHVYLGHG HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC AFGFGEGIKFYFQKNPMELSKEEMVLLASLPSAPNKYSPLKNPEDSYTRVRAILNMFRNR CCCCCCCEEEEEECCCCCCCHHHEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC GIYPNLDRDKLIGLYHNLSTRSPNETVFGSRHDIAPYVTEHVRSVLSSLEGEKNIYESGG CCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHCCC YTVETTLDRNAQEVIGPIVREYLAKNKRSGKIQKRRIRLKPESPLDLAFRQKMEEVSLLN EEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEHEEEECCCCCCHHHHHHHHHHHHHHH EFVWNPDQLESDKDQSIVQAAIVGIQPNTGQVLFLHGGDEFNSQNQFNRATQMRRQTGSS HHCCCCHHCCCCHHHHHHHHHHEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCH IKAVLYASAIDSGSIHAGMKILDAPLYYRGGGGKEWAPENLGGSFDGEISLRTALVKSKN HEEHHEEHHCCCCCCHHCHHHHCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEHHHHCCC TAAVQVAERLGSAGIEKYFTKFFFPNDAEKKNRYRGDLSLALGTLEISPLEMASAFTSFV HHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHH NQGNVKRPYLIQRIKNAKGNVLYEVGASDEFKLKLPEERQVIRPDTAEVMVSLLRDSGRA HCCCCCCHHHHHHHHCCCCCEEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCC SGVRNGGYTGDLIGKTGTTNDYKDAWFVGARPDLSLAVWVGYDNPKFGMGPSGLGGAVAA CCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEEECCCCCCCCCCCCCCCHHHH PLWGEILATIDKKSILPKIQFSLPVYAKAYKICTLTGKQASPTCPSTQELYLSDYPPEGP HHHHHHHHHHHHHHCCCEEEECCCHHHHHEEEEEEECCCCCCCCCCCHHEEECCCCCCCC CNDDHKSTSSDHKDLMKGLY CCCCCCCCCCHHHHHHHHCC >Mature Secondary Structure SAPSLKYLCPHCQKASRLPEPTPKEGKFQLTCAHCSEKVVLQFIDYRFEIVQVLPSAID CCCCCCHHCCCHHHHHCCCCCCCCCCCEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHH ESKQSYQSFKIPVPGISAQSKENFPSRSPSKPFFEKKIIWEKESKKPNPKPFAFSKRIPV HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHEECCCCCCCCCCCCCCCCCCCC LKKDPSKFSYWKVGFTITSITLFLFIVSFSYFVAGVLVTKKEVPLYLESLSKNIPTKILD CCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHC RNGQVVSEIFQKRTSTLHLQDYPEDMISILLNIEDQKFFFHGGIDYSAILRAFFKNIVNL CCCHHHHHHHHHHHCEEEECCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCC SYKQGASTITQQLARIILDDRRKSLNRKWREAQLAFALESVLTKEQILETYMNHVYLGHG HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC AFGFGEGIKFYFQKNPMELSKEEMVLLASLPSAPNKYSPLKNPEDSYTRVRAILNMFRNR CCCCCCCEEEEEECCCCCCCHHHEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC GIYPNLDRDKLIGLYHNLSTRSPNETVFGSRHDIAPYVTEHVRSVLSSLEGEKNIYESGG CCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHCCC YTVETTLDRNAQEVIGPIVREYLAKNKRSGKIQKRRIRLKPESPLDLAFRQKMEEVSLLN EEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEHEEEECCCCCCHHHHHHHHHHHHHHH EFVWNPDQLESDKDQSIVQAAIVGIQPNTGQVLFLHGGDEFNSQNQFNRATQMRRQTGSS HHCCCCHHCCCCHHHHHHHHHHEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCH IKAVLYASAIDSGSIHAGMKILDAPLYYRGGGGKEWAPENLGGSFDGEISLRTALVKSKN HEEHHEEHHCCCCCCHHCHHHHCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEHHHHCCC TAAVQVAERLGSAGIEKYFTKFFFPNDAEKKNRYRGDLSLALGTLEISPLEMASAFTSFV HHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHH NQGNVKRPYLIQRIKNAKGNVLYEVGASDEFKLKLPEERQVIRPDTAEVMVSLLRDSGRA HCCCCCCHHHHHHHHCCCCCEEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCC SGVRNGGYTGDLIGKTGTTNDYKDAWFVGARPDLSLAVWVGYDNPKFGMGPSGLGGAVAA CCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEEECCCCCCCCCCCCCCCHHHH PLWGEILATIDKKSILPKIQFSLPVYAKAYKICTLTGKQASPTCPSTQELYLSDYPPEGP HHHHHHHHHHHHHHCCCEEEECCCHHHHHEEEEEEECCCCCCCCCCCHHEEECCCCCCCC CNDDHKSTSSDHKDLMKGLY CCCCCCCCCCHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA