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The map label for this gene is degQ [H]

Identifier: 183219941

GI number: 183219941

Start: 521784

End: 522941

Strand: Direct

Name: degQ [H]

Synonym: LEPBI_I0523

Alternate gene names: 183219941

Gene position: 521784-522941 (Clockwise)

Preceding gene: 183219939

Following gene: 183219942

Centisome position: 14.5

GC content: 45.08

Gene sequence:

>1158_bases
TTGTCTATGACTGAGAAAAAAACGAATCCTTTACGATACATTGCCGTCGCGTTTAGCTTTTTATTACTCGGGACATTTTT
GTCTCCCATCTTAACATGCGGAAATTCTTCTGAAAACCCATTGCAACTCAAGGCAGATGGTGGCGAAAAATTATCACCAG
CCCAAACCCAAGCCGTTGCCTTAGAAGATGCCTTCCAAGAAGTTTTTGATAAAGTTTCCCCAAGTGTTGTTTCGATTGCC
ACGGAAGGAACGGTGAATGTGCCCTTACACCCGTTTGAGTATTTTTTTGGGAATCCCCAAAACCAAAGAAAAGGGTCTCG
CCAACAAAAACTTTCAGGGCTTGGTTCAGGCATCGTCCTCAATGAAGATGGTTACGTTATGACAAACCACCATGTTGTCC
AAAACATGGATAAGTTTACGGTGAAGTTAAAAAACAAAAGTGAATACGAAGCAAAACTCATTGGTTCGGATCCCACTGCC
GACATTGCCTTATTAAAAATCAGCGCTCCCAAAGGAACACTTGTGCCCAGTTTGATTGGCGACTCGAGTAAAGTCAGAGT
GGGGAATTGGGCGATCGCCATTGGTGCGCCCCTTGGCCTCGAACAATCGTTTACTGTAGGAGTGGTATCGGCCATCCAAA
GGGGGGGGCTTGATAAATCAGGTCTTGCCTACATCCAAACGGATGCTGCCATCAACCAAGGGAATAGTGGAGGGCCACTC
CTCAATATCCGAGGCGAAGTGATTGGGATCAACCGAATGATTGTGAGCCAATCTGGTGGGTCTGATGGAATTGGTTTTGC
CATTCCGATCAATGAAGCTCGTCGTGTTGTGGAAGAATTGAAGTTGAATGGAGTTGTCGCACGTGCATGGATTGGAGCTG
GGGTAGATTATATTACGGAACGTGACATCGCACAATTTGGTTTGAAAAACAACCAAGGGGCCATTGTCCACCAAATCTAC
AAGGGATCGCCTGCCAACAAAGCGGGATTACAACTGATGGATGTGATCATTGAATTTGATGGCAAACCAGTGCGCACTCC
AGATGAGCTCGTGGGAATGATTGTGAATTCCAAAATTGGCAAACGAGTCGAACTAAAAATCATCCGAAATAAAAATGAAA
TCTTGACGTCCATCACTCCAGAGAAGAAACCCAATTGA

Upstream 100 bases:

>100_bases
GTGTTACAAATTGTTCAAGTTTTTTTGTAAAAAAACGATCCCAAGAAATGGGAACTTTCCCGCCCTTCTTTGGGTCTGAT
ACTATAGGAGAGAGTATTCA

Downstream 100 bases:

>100_bases
GGTGAGTTTACGAGAAGATTGGATGCAAGCGGGCGAAGAAGAACCAAACCTTCGCCCCACAAAACTGTCTGAGTTCATTG
GACAAAAAGAGGTCTTAGCC

Product: putative serine-type endopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MSMTEKKTNPLRYIAVAFSFLLLGTFLSPILTCGNSSENPLQLKADGGEKLSPAQTQAVALEDAFQEVFDKVSPSVVSIA
TEGTVNVPLHPFEYFFGNPQNQRKGSRQQKLSGLGSGIVLNEDGYVMTNHHVVQNMDKFTVKLKNKSEYEAKLIGSDPTA
DIALLKISAPKGTLVPSLIGDSSKVRVGNWAIAIGAPLGLEQSFTVGVVSAIQRGGLDKSGLAYIQTDAAINQGNSGGPL
LNIRGEVIGINRMIVSQSGGSDGIGFAIPINEARRVVEELKLNGVVARAWIGAGVDYITERDIAQFGLKNNQGAIVHQIY
KGSPANKAGLQLMDVIIEFDGKPVRTPDELVGMIVNSKIGKRVELKIIRNKNEILTSITPEKKPN

Sequences:

>Translated_385_residues
MSMTEKKTNPLRYIAVAFSFLLLGTFLSPILTCGNSSENPLQLKADGGEKLSPAQTQAVALEDAFQEVFDKVSPSVVSIA
TEGTVNVPLHPFEYFFGNPQNQRKGSRQQKLSGLGSGIVLNEDGYVMTNHHVVQNMDKFTVKLKNKSEYEAKLIGSDPTA
DIALLKISAPKGTLVPSLIGDSSKVRVGNWAIAIGAPLGLEQSFTVGVVSAIQRGGLDKSGLAYIQTDAAINQGNSGGPL
LNIRGEVIGINRMIVSQSGGSDGIGFAIPINEARRVVEELKLNGVVARAWIGAGVDYITERDIAQFGLKNNQGAIVHQIY
KGSPANKAGLQLMDVIIEFDGKPVRTPDELVGMIVNSKIGKRVELKIIRNKNEILTSITPEKKPN
>Mature_384_residues
SMTEKKTNPLRYIAVAFSFLLLGTFLSPILTCGNSSENPLQLKADGGEKLSPAQTQAVALEDAFQEVFDKVSPSVVSIAT
EGTVNVPLHPFEYFFGNPQNQRKGSRQQKLSGLGSGIVLNEDGYVMTNHHVVQNMDKFTVKLKNKSEYEAKLIGSDPTAD
IALLKISAPKGTLVPSLIGDSSKVRVGNWAIAIGAPLGLEQSFTVGVVSAIQRGGLDKSGLAYIQTDAAINQGNSGGPLL
NIRGEVIGINRMIVSQSGGSDGIGFAIPINEARRVVEELKLNGVVARAWIGAGVDYITERDIAQFGLKNNQGAIVHQIYK
GSPANKAGLQLMDVIIEFDGKPVRTPDELVGMIVNSKIGKRVELKIIRNKNEILTSITPEKKPN

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=331, Percent_Identity=34.441087613293, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI24308541, Length=329, Percent_Identity=32.2188449848024, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI22129776, Length=333, Percent_Identity=33.6336336336336, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI7019477, Length=332, Percent_Identity=32.5301204819277, Blast_Score=144, Evalue=2e-34,
Organism=Escherichia coli, GI1789629, Length=334, Percent_Identity=41.6167664670659, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI1786356, Length=332, Percent_Identity=37.9518072289157, Blast_Score=204, Evalue=9e-54,
Organism=Escherichia coli, GI1789630, Length=282, Percent_Identity=35.1063829787234, Blast_Score=171, Evalue=8e-44,
Organism=Drosophila melanogaster, GI24646839, Length=362, Percent_Identity=31.4917127071823, Blast_Score=142, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 41290; Mature: 41159

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMTEKKTNPLRYIAVAFSFLLLGTFLSPILTCGNSSENPLQLKADGGEKLSPAQTQAVA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHH
LEDAFQEVFDKVSPSVVSIATEGTVNVPLHPFEYFFGNPQNQRKGSRQQKLSGLGSGIVL
HHHHHHHHHHHCCCCEEEEEECCEEECCCCHHHHHCCCCCHHHCCCHHHHHHCCCCCEEE
NEDGYVMTNHHVVQNMDKFTVKLKNKSEYEAKLIGSDPTADIALLKISAPKGTLVPSLIG
CCCCEEEECCHHHHCCCEEEEEECCCCCCEEEEECCCCCCCEEEEEEECCCCCCCHHHCC
DSSKVRVGNWAIAIGAPLGLEQSFTVGVVSAIQRGGLDKSGLAYIQTDAAINQGNSGGPL
CCCEEEECCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCHHCCCCCCCCE
LNIRGEVIGINRMIVSQSGGSDGIGFAIPINEARRVVEELKLNGVVARAWIGAGVDYITE
EEECCCEEEEEEEEEECCCCCCCCEEEEEHHHHHHHHHHHHHCCEEEEHHHHCCHHHHHH
RDIAQFGLKNNQGAIVHQIYKGSPANKAGLQLMDVIIEFDGKPVRTPDELVGMIVNSKIG
HHHHHHCCCCCCCCEEEEEECCCCCCHHHHHEEEHHHCCCCCCCCCHHHHHHHHHHHCCC
KRVELKIIRNKNEILTSITPEKKPN
CEEEEEEEECCCCEEEECCCCCCCC
>Mature Secondary Structure 
SMTEKKTNPLRYIAVAFSFLLLGTFLSPILTCGNSSENPLQLKADGGEKLSPAQTQAVA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHH
LEDAFQEVFDKVSPSVVSIATEGTVNVPLHPFEYFFGNPQNQRKGSRQQKLSGLGSGIVL
HHHHHHHHHHHCCCCEEEEEECCEEECCCCHHHHHCCCCCHHHCCCHHHHHHCCCCCEEE
NEDGYVMTNHHVVQNMDKFTVKLKNKSEYEAKLIGSDPTADIALLKISAPKGTLVPSLIG
CCCCEEEECCHHHHCCCEEEEEECCCCCCEEEEECCCCCCCEEEEEEECCCCCCCHHHCC
DSSKVRVGNWAIAIGAPLGLEQSFTVGVVSAIQRGGLDKSGLAYIQTDAAINQGNSGGPL
CCCEEEECCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCHHCCCCCCCCE
LNIRGEVIGINRMIVSQSGGSDGIGFAIPINEARRVVEELKLNGVVARAWIGAGVDYITE
EEECCCEEEEEEEEEECCCCCCCCEEEEEHHHHHHHHHHHHHCCEEEEHHHHCCHHHHHH
RDIAQFGLKNNQGAIVHQIYKGSPANKAGLQLMDVIIEFDGKPVRTPDELVGMIVNSKIG
HHHHHHCCCCCCCCEEEEEECCCCCCHHHHHEEEHHHCCCCCCCCCHHHHHHHHHHHCCC
KRVELKIIRNKNEILTSITPEKKPN
CEEEEEEEECCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]