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The map label for this gene is rsbV [H]

Identifier: 183219939

GI number: 183219939

Start: 520753

End: 521112

Strand: Direct

Name: rsbV [H]

Synonym: LEPBI_I0521

Alternate gene names: 183219939

Gene position: 520753-521112 (Clockwise)

Preceding gene: 183219938

Following gene: 183219941

Centisome position: 14.47

GC content: 40.0

Gene sequence:

>360_bases
ATGGTCATTCGCGAAACGTCTTCGAATCAGGTAGTTGTCATCACCATTGAAGGTGAAGTTGATTTGTACAATGCAAAAGA
ATTGAAAGACATTTTGGATGACAAAATGCGCAAACACCAATACGAGATCGTTGTGAATTTAGAAAAGGTTCCCTTTATGG
ATAGTTCTGGAATTGGAACTCTTGTGACCGCCATGTACAAACTTAAAAAATACCATGGCAATCTAAAGGTATGTAGTGTA
CATGGTTCCGTCGCCAAAGTGTTTAAAATGACTGGGATGGAAAGTCACTTAGAAGTGTTTGATACCGAAGAGATGGCAGT
CCAGTCTCTCATCAGCGAACGAAATTCTCACTCCGATTGA

Upstream 100 bases:

>100_bases
CCATCCTCAGTAGAAGGAAAGAAGAAAGAAAACCGTTCGGTGTCTTTCGAATGTAATTTTTTTCCTTTTCATTTCTTTTT
ATGGTGCAAACTTAAATCAA

Downstream 100 bases:

>100_bases
GGCAGTTGGAGTCCTTGTTTGACTCTCTCCATCACTTCCTTCCCTTCGAACAATTCCAACAAATACAAAGCAAATGCAAA
TGCTGATCCAGGTCCAACAC

Product: anti-sigma factor antagonist

Products: NA

Alternate protein names: Anti-anti-sigma-B factor [H]

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MVIRETSSNQVVVITIEGEVDLYNAKELKDILDDKMRKHQYEIVVNLEKVPFMDSSGIGTLVTAMYKLKKYHGNLKVCSV
HGSVAKVFKMTGMESHLEVFDTEEMAVQSLISERNSHSD

Sequences:

>Translated_119_residues
MVIRETSSNQVVVITIEGEVDLYNAKELKDILDDKMRKHQYEIVVNLEKVPFMDSSGIGTLVTAMYKLKKYHGNLKVCSV
HGSVAKVFKMTGMESHLEVFDTEEMAVQSLISERNSHSD
>Mature_119_residues
MVIRETSSNQVVVITIEGEVDLYNAKELKDILDDKMRKHQYEIVVNLEKVPFMDSSGIGTLVTAMYKLKKYHGNLKVCSV
HGSVAKVFKMTGMESHLEVFDTEEMAVQSLISERNSHSD

Specific function: Positive regulator of sigma-B activity. Non- phosphorylated rsbV binds to rsbW, preventing its association with sigma-B. When phosphorylated, releases rsbW, which is then free to complex with and inactivate sigma-B [H]

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003658
- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 13465; Mature: 13465

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIRETSSNQVVVITIEGEVDLYNAKELKDILDDKMRKHQYEIVVNLEKVPFMDSSGIGT
CEEECCCCCCEEEEEECCCEEECCHHHHHHHHHHHHHHCEEEEEEEECCCCCCCCCCHHH
LVTAMYKLKKYHGNLKVCSVHGSVAKVFKMTGMESHLEVFDTEEMAVQSLISERNSHSD
HHHHHHHHHHHCCCEEEEEECHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MVIRETSSNQVVVITIEGEVDLYNAKELKDILDDKMRKHQYEIVVNLEKVPFMDSSGIGT
CEEECCCCCCEEEEEECCCEEECCHHHHHHHHHHHHHHCEEEEEEEECCCCCCCCCCHHH
LVTAMYKLKKYHGNLKVCSVHGSVAKVFKMTGMESHLEVFDTEEMAVQSLISERNSHSD
HHHHHHHHHHHCCCEEEEEECHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]