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The map label for this gene is ydjH [C]

Identifier: 183219919

GI number: 183219919

Start: 498841

End: 499902

Strand: Direct

Name: ydjH [C]

Synonym: LEPBI_I0501

Alternate gene names: 183219919

Gene position: 498841-499902 (Clockwise)

Preceding gene: 183219913

Following gene: 183219922

Centisome position: 13.86

GC content: 40.21

Gene sequence:

>1062_bases
TTGCCAAACTGGAATAGGAAAATTGAGTGTCAATTCCCTAAAGGAAAAAAGCATTGTCCCATGAGACATTACGACGTATT
CGGCGTAGGGAACGCCCTGGTAGATATCATTGCCTTCATAGATCCAAAATTTTTAGAAAAACAAAATATCACCAAAGGTG
TGATGACCTTAGTTGATGAATCCAGGCAAGGTCAAATTCTTGCAGATCTTCATGATGAGAAGAAGGAACTTAGGTCAGGT
GGAAGTGCCGCAAACACGATGATTGCCATTGCCAATTCTGGTGGTACTTGCTGTTATACGGGAAAAGTCACTCATGATAC
ATATGGTGAATTTTATAAAAAAGATATGGAAGATGCGGGAGTTTTATTTGAGACCACTCCTGACAAATTAGGACATACGG
GAACTTGTGTAGTTCTCACAACACCTGACGCCGAAAGGACAATGCTTACCAATCTTGCGATTTCTACTTCACTTGGCCCT
GACGATATCGATATTGAAAACTTAAAAAAAAGTAAGTATGTCTATGTGGAAGGGTATTTATGGGATGGTGATTCCACAAA
AAAAGCAAGTGAACTTACGATGAAAATTGCAAAAGAAAACAAGGTAAAGGTATCCTTTACATACAGCGATCCTTTTTGTG
TGAATCGTTCTAGAGATGAGTTCATCCATTTAACAAAAGAATACGTTGATGTCGTTTTTTGTAATACAGAAGAAGGGCTT
GCCTTAAGTGGTGCCAAAACAGCTGAAGAAGCAGTACAATTTATATCTAAACTTTGTTCTTTGGTATTTATGACTGCAGG
AAAAGAGGGAGCTTATGTTGCTGAAAACGGCAAAATCACTTTGGTTCCTGGATTTCCTGTGAAGCCGATTGATACGACAG
GAGCAGGAGATGCTTTTGCGGCTGGGGTATTGTATGGCCTCACCCAAGGTTATTCTGCACAAAAGTCGGCAAGATGGGGC
AATTATGTTGCTTCGCGTATCGTTTGTGAGGTGGGACCAAGGTTATCTGTAAAACTTATGGGCCGCCAAGAAGAAATTTT
AACCGGTTTCCAAGATCAGTAA

Upstream 100 bases:

>100_bases
GGAGTCTCTTGCCCATATAGAAGAATTGGTCCGAGTAAGAATCCCATGCATAAAAATAAATTGAATTTGGAAACCATGAA
GTCCTTTTTTTCTCGGTACC

Downstream 100 bases:

>100_bases
TTTAAAAAAGAAATTACTGATGATGAAAATCCTCCCATAGGGTTTGGATTTTTTCTGAGATTTCAAGAGGGGCAAAGGGT
TTTTCAATCACACCAATGCC

Product: PfkB family carbohydrate kinase

Products: ADP; D-ribose 5-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MPNWNRKIECQFPKGKKHCPMRHYDVFGVGNALVDIIAFIDPKFLEKQNITKGVMTLVDESRQGQILADLHDEKKELRSG
GSAANTMIAIANSGGTCCYTGKVTHDTYGEFYKKDMEDAGVLFETTPDKLGHTGTCVVLTTPDAERTMLTNLAISTSLGP
DDIDIENLKKSKYVYVEGYLWDGDSTKKASELTMKIAKENKVKVSFTYSDPFCVNRSRDEFIHLTKEYVDVVFCNTEEGL
ALSGAKTAEEAVQFISKLCSLVFMTAGKEGAYVAENGKITLVPGFPVKPIDTTGAGDAFAAGVLYGLTQGYSAQKSARWG
NYVASRIVCEVGPRLSVKLMGRQEEILTGFQDQ

Sequences:

>Translated_353_residues
MPNWNRKIECQFPKGKKHCPMRHYDVFGVGNALVDIIAFIDPKFLEKQNITKGVMTLVDESRQGQILADLHDEKKELRSG
GSAANTMIAIANSGGTCCYTGKVTHDTYGEFYKKDMEDAGVLFETTPDKLGHTGTCVVLTTPDAERTMLTNLAISTSLGP
DDIDIENLKKSKYVYVEGYLWDGDSTKKASELTMKIAKENKVKVSFTYSDPFCVNRSRDEFIHLTKEYVDVVFCNTEEGL
ALSGAKTAEEAVQFISKLCSLVFMTAGKEGAYVAENGKITLVPGFPVKPIDTTGAGDAFAAGVLYGLTQGYSAQKSARWG
NYVASRIVCEVGPRLSVKLMGRQEEILTGFQDQ
>Mature_352_residues
PNWNRKIECQFPKGKKHCPMRHYDVFGVGNALVDIIAFIDPKFLEKQNITKGVMTLVDESRQGQILADLHDEKKELRSGG
SAANTMIAIANSGGTCCYTGKVTHDTYGEFYKKDMEDAGVLFETTPDKLGHTGTCVVLTTPDAERTMLTNLAISTSLGPD
DIDIENLKKSKYVYVEGYLWDGDSTKKASELTMKIAKENKVKVSFTYSDPFCVNRSRDEFIHLTKEYVDVVFCNTEEGLA
LSGAKTAEEAVQFISKLCSLVFMTAGKEGAYVAENGKITLVPGFPVKPIDTTGAGDAFAAGVLYGLTQGYSAQKSARWGN
YVASRIVCEVGPRLSVKLMGRQEEILTGFQDQ

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI32484975, Length=362, Percent_Identity=25.6906077348066, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI32484973, Length=347, Percent_Identity=26.5129682997118, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI5670342, Length=303, Percent_Identity=25.4125412541254, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI4557693, Length=306, Percent_Identity=25.8169934640523, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI87081971, Length=339, Percent_Identity=25.9587020648968, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1788417, Length=275, Percent_Identity=24, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1790193, Length=239, Percent_Identity=23.8493723849372, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17541820, Length=330, Percent_Identity=27.5757575757576, Blast_Score=96, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6322565, Length=335, Percent_Identity=29.2537313432836, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21355521, Length=351, Percent_Identity=24.7863247863248, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24663633, Length=343, Percent_Identity=24.4897959183673, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571668, Length=334, Percent_Identity=23.9520958083832, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356339, Length=338, Percent_Identity=24.5562130177515, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: 2.7.1.15

Molecular weight: Translated: 38777; Mature: 38645

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNWNRKIECQFPKGKKHCPMRHYDVFGVGNALVDIIAFIDPKFLEKQNITKGVMTLVDE
CCCCCCEEEEECCCCCCCCCCCCEEEEECHHHHHHHHHHHCHHHHHHCCCHHHHHHHHCC
SRQGQILADLHDEKKELRSGGSAANTMIAIANSGGTCCYTGKVTHDTYGEFYKKDMEDAG
CCCCCEEEHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHCC
VLFETTPDKLGHTGTCVVLTTPDAERTMLTNLAISTSLGPDDIDIENLKKSKYVYVEGYL
EEEECCHHHCCCCCEEEEEECCCCHHHHHHHEEEECCCCCCCCCHHHCCCCEEEEEEEEE
WDGDSTKKASELTMKIAKENKVKVSFTYSDPFCVNRSRDEFIHLTKEYVDVVFCNTEEGL
ECCCCCCCHHHHHHEEECCCEEEEEEEECCCEEECCCHHHHHHHHHHCEEEEEECCCCCC
ALSGAKTAEEAVQFISKLCSLVFMTAGKEGAYVAENGKITLVPGFPVKPIDTTGAGDAFA
EECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEECCCCCCCCCCCCCCHHHH
AGVLYGLTQGYSAQKSARWGNYVASRIVCEVGPRLSVKLMGRQEEILTGFQDQ
HHHHHHHHCCCCCHHHCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCC
>Mature Secondary Structure 
PNWNRKIECQFPKGKKHCPMRHYDVFGVGNALVDIIAFIDPKFLEKQNITKGVMTLVDE
CCCCCEEEEECCCCCCCCCCCCEEEEECHHHHHHHHHHHCHHHHHHCCCHHHHHHHHCC
SRQGQILADLHDEKKELRSGGSAANTMIAIANSGGTCCYTGKVTHDTYGEFYKKDMEDAG
CCCCCEEEHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHCC
VLFETTPDKLGHTGTCVVLTTPDAERTMLTNLAISTSLGPDDIDIENLKKSKYVYVEGYL
EEEECCHHHCCCCCEEEEEECCCCHHHHHHHEEEECCCCCCCCCHHHCCCCEEEEEEEEE
WDGDSTKKASELTMKIAKENKVKVSFTYSDPFCVNRSRDEFIHLTKEYVDVVFCNTEEGL
ECCCCCCCHHHHHHEEECCCEEEEEEEECCCEEECCCHHHHHHHHHHCEEEEEECCCCCC
ALSGAKTAEEAVQFISKLCSLVFMTAGKEGAYVAENGKITLVPGFPVKPIDTTGAGDAFA
EECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEECCCCCCCCCCCCCCHHHH
AGVLYGLTQGYSAQKSARWGNYVASRIVCEVGPRLSVKLMGRQEEILTGFQDQ
HHHHHHHHCCCCCHHHCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-ribose

Specific reaction: ATP + D-ribose = ADP + D-ribose 5-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]