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The map label for this gene is tsr [H]

Identifier: 183219902

GI number: 183219902

Start: 478194

End: 479969

Strand: Direct

Name: tsr [H]

Synonym: LEPBI_I0484

Alternate gene names: 183219902

Gene position: 478194-479969 (Clockwise)

Preceding gene: 183219901

Following gene: 183219903

Centisome position: 13.28

GC content: 33.84

Gene sequence:

>1776_bases
ATGAAACCAAAAGAAATTATTTCCAAACCAAAATCAAAAAGTTTTTTCCTAGTTTATACACTCTTTACCAATTTGGATCC
ATTTTTATTCTTTGTAGGGATATTTCTTATTTTTGGTTGGGCAAATTTTGCATCCTTTATTAAAATTTTACTCTACTTAG
CACCCCCCATTATAGGATTTCACTCGCTTCTGTTTTTTCTGAAACATAAAGAGTTTAAAAAACTATTATATCGTCCAGAA
GAGATCCCCTATACTGAAAAAGAACTCAATATCATTCGCAAACTTTCCAAAAATGGAGCACTCAATATTCTTTCTACGAA
TGTGGGGGGACCTATTCTCACAATGGTCCTTGCTTACCATTTTGGTATGGTAAGATCTTATGGTGAAGTCGTGTTTCTTT
CTTTGTTAGGTGTATTACTTGCGATGGCAATTTCTTCTTTTTTCTACGTTTATGTTGAGCAAAGAATGTATGATGTTTAC
AATCAATTGAAACTCAAACCTCTCAGTTTGTTTGCTAATTTATTTTTCCCTATTTTTTCTACATTTGTGATCGAATACTT
TTTGTTTTCATTTTACATCTATTCACAATTTCGAAGTCATGTTGATGTCAACCAATTACAATTGATCTGTATTGGATTGA
GTTTTTTCATAATATTGATCATTTCTTTATTGTTTTTTGTTCTATGGAAATTGACAGGTAATACATCAGCAACCATCCGA
GATGTATCCGATATCTTGAAATCTTTCGCCGAAGGTGATTTACGTTCTGATGTTCGAATCAATGAAACTCGAAATGAAAT
TGGTGTAATCTCTCTCTATTTAGAAGAAGCAAAAACAAAACTCAATCGCCTATTGACTTCAATTATAAACCATTCTTCCA
AAATCCAATTAGAAGCAAAAACGTTAGAAGGTTTATCAAGTGAGTCAGCAGAACATTCACAAGTTCAAGCTGCTTCTTTA
GAAGAGGTTGCTGCAGCATTAGAAGAAAATGGGTCATCCATCAATGGAATTTATTCGGATGCTTTAGAACAAAAAAAATT
AACGGCCGCTACAAATGAATCCATTGAACATTTATTTACAATATCATCCAGTGTGAAAGATATTTCGCTTCATGCCAAAG
AGAAGGCAGACTCGGTAGAATCTGAAGTAATCAAAAGTGGAAAATCAATTACAAGTGCAATCCAATCCATAGAAGAAGTA
GACAAAAATGCAGTTGAAATTGGAAAAATTTTGGAGATCATAAAAGATATTTCGGAACAAGTCAACTTACTTGCGTTAAA
TGCTTCAATTGAGGCAGCTCGTGCTGGTGATATGGGAAGAGGATTTGCTGTGGTTGCTTCCGAAGTGGGAAAACTCGCCG
AAAGAACCGCATCTTCTACAAAAACCATATCAGATCTTATCAAACGAGTTTCCATTTCAACTCATATGTCGGTTGATTCT
GTAAAATCTGCGAGCGAGACATTCCGTTATCTATCAGAAAGTGTCATCGAGATCATCAATAATATAGATAAGGTAAACCA
AGCCAATTTAGAACAAATCACAGAAGTGGAAGAAATTAGAAAACAATCGGAAAATATAGTCAATAGGTCCTCTTCTGTTT
CGTTTGCAACGGAAGAACAAAAAAAAGTAAATGAAGAGATGGGAACGTCCGTCCATCATTTGGCAAATGATACAGCAAAA
TTATCGATGATGTCTGAAAAAACAGCTAAATCATCGGCTGAATTAAATTCTCTCATTGTCGAATTGAACAAAGAATTATC
TTTGTTTAAATTATGA

Upstream 100 bases:

>100_bases
TCTTATGGTATCTACTCATATCATAAGATCAAGGAATTCGAATCAAAAGATTAAATTCATTTGACAGAGGAATTAGAATC
CTTTTAAAATTCCTCTGTCA

Downstream 100 bases:

>100_bases
TCTCTGCAACATTTCTATTCAAACAATTTGCTTCTGATCCAGTATTTGAGTCCTTAGACCAATCTATCGAGAATTTTGTA
ACCAACCATCCTGAATATTT

Product: putative methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: MCP-I; Serine chemoreceptor protein [H]

Number of amino acids: Translated: 591; Mature: 591

Protein sequence:

>591_residues
MKPKEIISKPKSKSFFLVYTLFTNLDPFLFFVGIFLIFGWANFASFIKILLYLAPPIIGFHSLLFFLKHKEFKKLLYRPE
EIPYTEKELNIIRKLSKNGALNILSTNVGGPILTMVLAYHFGMVRSYGEVVFLSLLGVLLAMAISSFFYVYVEQRMYDVY
NQLKLKPLSLFANLFFPIFSTFVIEYFLFSFYIYSQFRSHVDVNQLQLICIGLSFFIILIISLLFFVLWKLTGNTSATIR
DVSDILKSFAEGDLRSDVRINETRNEIGVISLYLEEAKTKLNRLLTSIINHSSKIQLEAKTLEGLSSESAEHSQVQAASL
EEVAAALEENGSSINGIYSDALEQKKLTAATNESIEHLFTISSSVKDISLHAKEKADSVESEVIKSGKSITSAIQSIEEV
DKNAVEIGKILEIIKDISEQVNLLALNASIEAARAGDMGRGFAVVASEVGKLAERTASSTKTISDLIKRVSISTHMSVDS
VKSASETFRYLSESVIEIINNIDKVNQANLEQITEVEEIRKQSENIVNRSSSVSFATEEQKKVNEEMGTSVHHLANDTAK
LSMMSEKTAKSSAELNSLIVELNKELSLFKL

Sequences:

>Translated_591_residues
MKPKEIISKPKSKSFFLVYTLFTNLDPFLFFVGIFLIFGWANFASFIKILLYLAPPIIGFHSLLFFLKHKEFKKLLYRPE
EIPYTEKELNIIRKLSKNGALNILSTNVGGPILTMVLAYHFGMVRSYGEVVFLSLLGVLLAMAISSFFYVYVEQRMYDVY
NQLKLKPLSLFANLFFPIFSTFVIEYFLFSFYIYSQFRSHVDVNQLQLICIGLSFFIILIISLLFFVLWKLTGNTSATIR
DVSDILKSFAEGDLRSDVRINETRNEIGVISLYLEEAKTKLNRLLTSIINHSSKIQLEAKTLEGLSSESAEHSQVQAASL
EEVAAALEENGSSINGIYSDALEQKKLTAATNESIEHLFTISSSVKDISLHAKEKADSVESEVIKSGKSITSAIQSIEEV
DKNAVEIGKILEIIKDISEQVNLLALNASIEAARAGDMGRGFAVVASEVGKLAERTASSTKTISDLIKRVSISTHMSVDS
VKSASETFRYLSESVIEIINNIDKVNQANLEQITEVEEIRKQSENIVNRSSSVSFATEEQKKVNEEMGTSVHHLANDTAK
LSMMSEKTAKSSAELNSLIVELNKELSLFKL
>Mature_591_residues
MKPKEIISKPKSKSFFLVYTLFTNLDPFLFFVGIFLIFGWANFASFIKILLYLAPPIIGFHSLLFFLKHKEFKKLLYRPE
EIPYTEKELNIIRKLSKNGALNILSTNVGGPILTMVLAYHFGMVRSYGEVVFLSLLGVLLAMAISSFFYVYVEQRMYDVY
NQLKLKPLSLFANLFFPIFSTFVIEYFLFSFYIYSQFRSHVDVNQLQLICIGLSFFIILIISLLFFVLWKLTGNTSATIR
DVSDILKSFAEGDLRSDVRINETRNEIGVISLYLEEAKTKLNRLLTSIINHSSKIQLEAKTLEGLSSESAEHSQVQAASL
EEVAAALEENGSSINGIYSDALEQKKLTAATNESIEHLFTISSSVKDISLHAKEKADSVESEVIKSGKSITSAIQSIEEV
DKNAVEIGKILEIIKDISEQVNLLALNASIEAARAGDMGRGFAVVASEVGKLAERTASSTKTISDLIKRVSISTHMSVDS
VKSASETFRYLSESVIEIINNIDKVNQANLEQITEVEEIRKQSENIVNRSSSVSFATEEQKKVNEEMGTSVHHLANDTAK
LSMMSEKTAKSSAELNSLIVELNKELSLFKL

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=380, Percent_Identity=25.7894736842105, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1787690, Length=347, Percent_Identity=25.3602305475504, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788194, Length=228, Percent_Identity=31.140350877193, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788195, Length=296, Percent_Identity=25.6756756756757, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1789453, Length=295, Percent_Identity=25.7627118644068, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 66128; Mature: 66128

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC
>Mature Secondary Structure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HHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6402709; 7610040; 9278503; 8384293; 6213619; 2033064; 10466731 [H]