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The map label for this gene is bvgS [H]

Identifier: 183219846

GI number: 183219846

Start: 417524

End: 419656

Strand: Reverse

Name: bvgS [H]

Synonym: LEPBI_I0424

Alternate gene names: 183219846

Gene position: 419656-417524 (Counterclockwise)

Preceding gene: 183219847

Following gene: 183219843

Centisome position: 11.66

GC content: 35.96

Gene sequence:

>2133_bases
TTGACTTCCTCCAATACTAAATTTCCAAAATATGATTTTCAAAATATTTTTCAATCATTGCCTGAACTATATATGCTTTT
GGATTTGGATTTTTGTATCATTGATATCAGCGATGCGTATGCAAATGCGACGTTAATCAAAAGGGAAAATGTTGTCGGAC
AGAATCTTTTTGAAGTATTCCCTGACAATCCAGAGGATCAATCCGCGGATGGTGTCAAACAACTTCGTTCCTCGCTTAAG
CAAGTGCTTAACTACAAACGCACGAGCACAATGGCATTACAAAAATATGATATAACAAAGCCGGATGGAAGTGGATTTGA
AGTTCGATATTGGAGTCCTAGAAATTCACCAGTTTTTAATTCCAATGGAGATTTAGTCTGTATTGTACATACGGCAGAAG
ATGTTACGGATTTTGTATATTTAAAACAACAAAGAGTAGAACAGTCGGAACAAACAGATGAAATGACAGAGCGCATTTCA
AAAATGGAATCCGAAGTGATTACCCGTGCAAAAGAAGTAATTGAAAAAAATGAAGCATTACTTAACAGCGAACAAAATTT
ATCTATCACACTCAGTTCTATCGGCGATGCTGTTCTTGCTACGGATGAACATGGAATCATCAATCGATTAAATCCTGTTG
CAGAATCTCTTATCGGTTGGACAGCAAAAGAAGCGATCGGTAAAAACGTAAACGAAGTATTACAATTAGTGTATGCATCC
TCTGGTTTACCCAAAAGCATTCCCATCTTCGAAGTCATCTCTAACGGAACTGTCAAAGGAAGTAGCCAAGATGGAATTTT
AATCCACCGCTATGGAAGAAAAATAAATATTTCTGATACATGTTCACCCATTCGAAATAAAAACGGTGAAATCATTGGAT
CGATTTTAGTTTTTCGCGATATATCGGAAGAATTTGCTGCAAAAACATATCTGGAAAAGGCAAAAGAAAATGCAGAAATG
GCAAACAAAGCAAAGGATTCTTTTCTCGCAACAATGAGCCATGAAATCCGTACACCACTTAGTGGGCTTATCGGTATGTT
AGAGTTACTCTATCAAACTTCATTAAATGATGACCAAAAAAGTTTAGTGAATAATGCATTGGTTTCAGGCAACAGCTTAC
TACGTATCCTTAGCGATATTCTTGATCTTTCAAAAATAGAAGAGGGAAAATTAGAATTATCACTTCAACCAACATCAATT
AGTCGACTACTCTCCGAAGTAGCGACAACCTATTTACAAATCGCAAGTTCAAAAGGATTGACATTAAGTTATGCTGTGGA
TGAAAAAATTACATCTGCGCATATATTGGATTCTTTACGTTTGTCTCAGATTATCAATAATTTTGTAAGCAATGGTATTA
AATTTACATCGAAAGGAAGTATTCATATTTCAGCGAACTTAATTAAAAATATTGATACATTACAACAAATCCAATTTTCC
GTCACTGATACAGGAATAGGCCTCAGCAAAACTGATCAATCAAAATTATTCCAGTCTTATACGCAGGCCACAGCTGACAC
TGCTCGATTGTACGGTGGCACTGGACTTGGACTTGCTATCTGTATGAGATTGTCTGAACTGATGGACGGAAACATAACGA
TTGATAGTTTACCAGGTTCTGGGTCTACATTTAGTATTACATTGTCGCTTCCCACAACGGAAATGGATACCAAAAACGAG
AATTCAAAGGAAAATGCCCCAAAAACAATTGAACCAATTTTTTTTACAGAATTTGATCCTCCTCGAATATTAGCTGTTGA
TGACAATTCAGTCAATTTAGAAATTATTTTACGCCAATTGAAAGTTTTTGGTCTGGAAGTCGATGGAGCTGATGATGGGG
AAAAGGCTTTGCAGTTGTGGTTAAACAATAAATACGATCTCATCATAACCGATTGCCATATGCCCATAAAAGATGGTTAT
ACATTAACCAAAGAGATCCGAAATATAGAAAAATCAAAATTTGAAAAACGAATACCGATTATCGGTTACACTGCCAATGC
TTTGGTGGAAGAAAGAGAGTATTGTTTGTCCATAGGAATGGATGAGCTTTTGATCAAACCAGCTCGATTGTCAAATCTAA
GAGAAACTCTTGTTAAATGGTTGCCAAATCAAATTCAATCGATTGACCAATAG

Upstream 100 bases:

>100_bases
TTGATTGATCACTCTCTATTTTTATGTTCTACTATTCTAATTTGTTTTTTCAACTTTGTTTTAGAAAAAATCCTTTGATG
ACAAAAAGCTAGGCTCGAAA

Downstream 100 bases:

>100_bases
TATTTGGAAATCTACTGCATTTTAAATATCTCCATTTTGACTTAAGAGATTAAAAAGTTCCTGCACGGAATTTTGTAAGG
TCACTTGGAACATCTACCTT

Product: putative two-component sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 710; Mature: 709

Protein sequence:

>710_residues
MTSSNTKFPKYDFQNIFQSLPELYMLLDLDFCIIDISDAYANATLIKRENVVGQNLFEVFPDNPEDQSADGVKQLRSSLK
QVLNYKRTSTMALQKYDITKPDGSGFEVRYWSPRNSPVFNSNGDLVCIVHTAEDVTDFVYLKQQRVEQSEQTDEMTERIS
KMESEVITRAKEVIEKNEALLNSEQNLSITLSSIGDAVLATDEHGIINRLNPVAESLIGWTAKEAIGKNVNEVLQLVYAS
SGLPKSIPIFEVISNGTVKGSSQDGILIHRYGRKINISDTCSPIRNKNGEIIGSILVFRDISEEFAAKTYLEKAKENAEM
ANKAKDSFLATMSHEIRTPLSGLIGMLELLYQTSLNDDQKSLVNNALVSGNSLLRILSDILDLSKIEEGKLELSLQPTSI
SRLLSEVATTYLQIASSKGLTLSYAVDEKITSAHILDSLRLSQIINNFVSNGIKFTSKGSIHISANLIKNIDTLQQIQFS
VTDTGIGLSKTDQSKLFQSYTQATADTARLYGGTGLGLAICMRLSELMDGNITIDSLPGSGSTFSITLSLPTTEMDTKNE
NSKENAPKTIEPIFFTEFDPPRILAVDDNSVNLEIILRQLKVFGLEVDGADDGEKALQLWLNNKYDLIITDCHMPIKDGY
TLTKEIRNIEKSKFEKRIPIIGYTANALVEEREYCLSIGMDELLIKPARLSNLRETLVKWLPNQIQSIDQ

Sequences:

>Translated_710_residues
MTSSNTKFPKYDFQNIFQSLPELYMLLDLDFCIIDISDAYANATLIKRENVVGQNLFEVFPDNPEDQSADGVKQLRSSLK
QVLNYKRTSTMALQKYDITKPDGSGFEVRYWSPRNSPVFNSNGDLVCIVHTAEDVTDFVYLKQQRVEQSEQTDEMTERIS
KMESEVITRAKEVIEKNEALLNSEQNLSITLSSIGDAVLATDEHGIINRLNPVAESLIGWTAKEAIGKNVNEVLQLVYAS
SGLPKSIPIFEVISNGTVKGSSQDGILIHRYGRKINISDTCSPIRNKNGEIIGSILVFRDISEEFAAKTYLEKAKENAEM
ANKAKDSFLATMSHEIRTPLSGLIGMLELLYQTSLNDDQKSLVNNALVSGNSLLRILSDILDLSKIEEGKLELSLQPTSI
SRLLSEVATTYLQIASSKGLTLSYAVDEKITSAHILDSLRLSQIINNFVSNGIKFTSKGSIHISANLIKNIDTLQQIQFS
VTDTGIGLSKTDQSKLFQSYTQATADTARLYGGTGLGLAICMRLSELMDGNITIDSLPGSGSTFSITLSLPTTEMDTKNE
NSKENAPKTIEPIFFTEFDPPRILAVDDNSVNLEIILRQLKVFGLEVDGADDGEKALQLWLNNKYDLIITDCHMPIKDGY
TLTKEIRNIEKSKFEKRIPIIGYTANALVEEREYCLSIGMDELLIKPARLSNLRETLVKWLPNQIQSIDQ
>Mature_709_residues
TSSNTKFPKYDFQNIFQSLPELYMLLDLDFCIIDISDAYANATLIKRENVVGQNLFEVFPDNPEDQSADGVKQLRSSLKQ
VLNYKRTSTMALQKYDITKPDGSGFEVRYWSPRNSPVFNSNGDLVCIVHTAEDVTDFVYLKQQRVEQSEQTDEMTERISK
MESEVITRAKEVIEKNEALLNSEQNLSITLSSIGDAVLATDEHGIINRLNPVAESLIGWTAKEAIGKNVNEVLQLVYASS
GLPKSIPIFEVISNGTVKGSSQDGILIHRYGRKINISDTCSPIRNKNGEIIGSILVFRDISEEFAAKTYLEKAKENAEMA
NKAKDSFLATMSHEIRTPLSGLIGMLELLYQTSLNDDQKSLVNNALVSGNSLLRILSDILDLSKIEEGKLELSLQPTSIS
RLLSEVATTYLQIASSKGLTLSYAVDEKITSAHILDSLRLSQIINNFVSNGIKFTSKGSIHISANLIKNIDTLQQIQFSV
TDTGIGLSKTDQSKLFQSYTQATADTARLYGGTGLGLAICMRLSELMDGNITIDSLPGSGSTFSITLSLPTTEMDTKNEN
SKENAPKTIEPIFFTEFDPPRILAVDDNSVNLEIILRQLKVFGLEVDGADDGEKALQLWLNNKYDLIITDCHMPIKDGYT
LTKEIRNIEKSKFEKRIPIIGYTANALVEEREYCLSIGMDELLIKPARLSNLRETLVKWLPNQIQSIDQ

Specific function: Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=404, Percent_Identity=37.3762376237624, Blast_Score=225, Evalue=8e-60,
Organism=Escherichia coli, GI48994928, Length=584, Percent_Identity=26.8835616438356, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1789149, Length=240, Percent_Identity=43.3333333333333, Blast_Score=182, Evalue=9e-47,
Organism=Escherichia coli, GI145693157, Length=278, Percent_Identity=37.0503597122302, Blast_Score=168, Evalue=1e-42,
Organism=Escherichia coli, GI87081816, Length=405, Percent_Identity=30.3703703703704, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI1788549, Length=394, Percent_Identity=23.3502538071066, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1788393, Length=243, Percent_Identity=30.8641975308642, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1786600, Length=357, Percent_Identity=25.4901960784314, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786912, Length=249, Percent_Identity=26.9076305220884, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1788381, Length=134, Percent_Identity=36.5671641791045, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790436, Length=276, Percent_Identity=26.0869565217391, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1786783, Length=225, Percent_Identity=23.5555555555556, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=104, Percent_Identity=37.5, Blast_Score=68, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322000, Length=129, Percent_Identity=29.4573643410853, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 78985; Mature: 78854

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSNTKFPKYDFQNIFQSLPELYMLLDLDFCIIDISDAYANATLIKRENVVGQNLFEVF
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECHHHCCEEEEECCCHHHHHHHHHC
PDNPEDQSADGVKQLRSSLKQVLNYKRTSTMALQKYDITKPDGSGFEVRYWSPRNSPVFN
CCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHEEEEEECCCCCCCCEEEEEECCCCCCCCC
SNGDLVCIVHTAEDVTDFVYLKQQRVEQSEQTDEMTERISKMESEVITRAKEVIEKNEAL
CCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNSEQNLSITLSSIGDAVLATDEHGIINRLNPVAESLIGWTAKEAIGKNVNEVLQLVYAS
HCCCCCCEEEHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
SGLPKSIPIFEVISNGTVKGSSQDGILIHRYGRKINISDTCSPIRNKNGEIIGSILVFRD
CCCCCCCCHHHHHCCCEECCCCCCCEEEEECCCEECCCCCCCHHHCCCCCEEEHHHHHHH
ISEEFAAKTYLEKAKENAEMANKAKDSFLATMSHEIRTPLSGLIGMLELLYQTSLNDDQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHH
SLVNNALVSGNSLLRILSDILDLSKIEEGKLELSLQPTSISRLLSEVATTYLQIASSKGL
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCC
TLSYAVDEKITSAHILDSLRLSQIINNFVSNGIKFTSKGSIHISANLIKNIDTLQQIQFS
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEHHHHHHHHHHHHHEEE
VTDTGIGLSKTDQSKLFQSYTQATADTARLYGGTGLGLAICMRLSELMDGNITIDSLPGS
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCC
GSTFSITLSLPTTEMDTKNENSKENAPKTIEPIFFTEFDPPRILAVDDNSVNLEIILRQL
CCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCHHHHHHHH
KVFGLEVDGADDGEKALQLWLNNKYDLIITDCHMPIKDGYTLTKEIRNIEKSKFEKRIPI
HHHEEEECCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCE
IGYTANALVEEREYCLSIGMDELLIKPARLSNLRETLVKWLPNQIQSIDQ
EEECHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHCCHHHHHCCC
>Mature Secondary Structure 
TSSNTKFPKYDFQNIFQSLPELYMLLDLDFCIIDISDAYANATLIKRENVVGQNLFEVF
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECHHHCCEEEEECCCHHHHHHHHHC
PDNPEDQSADGVKQLRSSLKQVLNYKRTSTMALQKYDITKPDGSGFEVRYWSPRNSPVFN
CCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHEEEEEECCCCCCCCEEEEEECCCCCCCCC
SNGDLVCIVHTAEDVTDFVYLKQQRVEQSEQTDEMTERISKMESEVITRAKEVIEKNEAL
CCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNSEQNLSITLSSIGDAVLATDEHGIINRLNPVAESLIGWTAKEAIGKNVNEVLQLVYAS
HCCCCCCEEEHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
SGLPKSIPIFEVISNGTVKGSSQDGILIHRYGRKINISDTCSPIRNKNGEIIGSILVFRD
CCCCCCCCHHHHHCCCEECCCCCCCEEEEECCCEECCCCCCCHHHCCCCCEEEHHHHHHH
ISEEFAAKTYLEKAKENAEMANKAKDSFLATMSHEIRTPLSGLIGMLELLYQTSLNDDQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHH
SLVNNALVSGNSLLRILSDILDLSKIEEGKLELSLQPTSISRLLSEVATTYLQIASSKGL
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCC
TLSYAVDEKITSAHILDSLRLSQIINNFVSNGIKFTSKGSIHISANLIKNIDTLQQIQFS
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEHHHHHHHHHHHHHEEE
VTDTGIGLSKTDQSKLFQSYTQATADTARLYGGTGLGLAICMRLSELMDGNITIDSLPGS
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCC
GSTFSITLSLPTTEMDTKNENSKENAPKTIEPIFFTEFDPPRILAVDDNSVNLEIILRQL
CCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCHHHHHHHH
KVFGLEVDGADDGEKALQLWLNNKYDLIITDCHMPIKDGYTLTKEIRNIEKSKFEKRIPI
HHHEEEECCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCE
IGYTANALVEEREYCLSIGMDELLIKPARLSNLRETLVKWLPNQIQSIDQ
EEECHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1791760; 12910271 [H]