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The map label for this gene is mcp4 [H]

Identifier: 183219844

GI number: 183219844

Start: 415046

End: 416572

Strand: Direct

Name: mcp4 [H]

Synonym: LEPBI_I0422

Alternate gene names: 183219844

Gene position: 415046-416572 (Clockwise)

Preceding gene: 183219835

Following gene: 183219845

Centisome position: 11.53

GC content: 35.23

Gene sequence:

>1527_bases
ATGATAGCGAACACGATTCGTATTTCCTTTGCAATTGTTATGTTATCTATCAATATTTTCTTTATGGTGGCGATTCCAAC
TACCGAAAAAACGATGAGCCTTATTTTATCATTTCTAGAATTAATAGTTTTGTCATATGGTGTTTATACCTTTTGGCTTT
ATAAAAAACAAAAATTCTTTTTAAAATTTGCATACGTCTCCATCATACTCGATATCATCATTTATTCGAGTGTTTTCGCC
ATTGTTGTCATTATGTCCAAAACTCCTGCAGAAAAGGTTTCGATTGCAACATTACCATTTGTAATGTTGGTTCTACTATT
TGTCGTTATTTACTCAGGTTTTCTTTTGTCATATCGTTTGACTATGACAGTTGGATACATTGCAATTTCAAGTTTACTTC
TATATGTATTTTTAGGAGTAAAGGGTGGTGCTGAAATTAAATTTATTGCGACTGCTGCAAATCAATTTGGGATTCCATTC
ATTGGGATTAATACAATTGCTTTGATTTGTGGTGTGCATATGATGAGTGCCGTCGTAAAATTTATGTCGAATTCTAGTAT
TGAAGCAACAAAATCTGCCGAAGAAGCAAGACTAAAATCTGAATCCGCAAACCAAACAAAGCAAAACATCCAACAAGAAG
CGGAAACGTTGAATCAAAGTGTCCAAGAAATGTTAAAATTTATGGATTCATTGAACACTGAAATCCAAACACAAGTTTCT
AGTGTCGAGGAGATCAGTGCGTCTATGGAAGAACTTGCAGCTTCAATGGACAGTGCTAGCGATTTTGTGAAATCACAGTT
TACGAGAATAGATGATTTAAACCAAGAAAGTTCCGTGATGGATAAAATTTTGTCCGAAGTATACAGTTCAACGATCAATT
TGGCACAAACCACTGATGAATCAAAACAATATAGTGTTCAAGTAACGACAGCTATGGATTCAGTTAGCTCCAATTTTGAA
GAAATTAAAGAAAGTTTTCAAAAAGTGGAAGAAGTGAACCAAATTTTACGAGACATAGCTGATCGAACCAACTTACTTGC
ATTAAATGCTTCTATTGAAGCAGCTCGCGCTGGTGAACATGGAAGAGGTTTTGCTGTAGTAGCTCAAGAAGTCGCTAAAC
TTGCTGACAGTGCACAGGAAAATGCATCACTAATATCAAAAATCATTACACAAGCTGCTAAACAAATTGTGAGCGGAAAT
ACGGCCGCTTATGAAACGAAAGAAAAAATGGGAATCCAGGATAAAAGTTTTGGTATCCTCGTTTCAAACCTTTCTGATTT
AAAAATTCGAGTAGAAAAACAAACATCCATTCATAAATCTTTTTTAAATTCATTCCAAGAATTGTTTTCACTTTCCAAAC
AATTGGAAGTTTTGGCATCAGAACAAAAAACGGGTACACAAGAAATGTCGAGAGCGCTTGTATCGATTGAACAATCTGCT
TCGTCGCTTGCATCCAATACCTCCCACTTGCGTGAAAATGTGGATGGACTCTCAAAACAATCACAACGATTGGCAAATCA
CATTTAA

Upstream 100 bases:

>100_bases
AAAAATAACCTATGTCGATATTTTAAAAAAATATCGTCTATCAATATGGGGATTTTGCCTTATGACATCAGTTTCTGGAA
ACTACTTAGAAAAGGGAAGT

Downstream 100 bases:

>100_bases
GATTGGAGCGAGTATCCGGAAATGTGCTGGCAAAAAAAAACTAAGTCTCCGATACTCACCTTAAAGATCTAGCAAATGCT
TTCCCAGATTCAGTAGTGCT

Product: putative methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MIANTIRISFAIVMLSINIFFMVAIPTTEKTMSLILSFLELIVLSYGVYTFWLYKKQKFFLKFAYVSIILDIIIYSSVFA
IVVIMSKTPAEKVSIATLPFVMLVLLFVVIYSGFLLSYRLTMTVGYIAISSLLLYVFLGVKGGAEIKFIATAANQFGIPF
IGINTIALICGVHMMSAVVKFMSNSSIEATKSAEEARLKSESANQTKQNIQQEAETLNQSVQEMLKFMDSLNTEIQTQVS
SVEEISASMEELAASMDSASDFVKSQFTRIDDLNQESSVMDKILSEVYSSTINLAQTTDESKQYSVQVTTAMDSVSSNFE
EIKESFQKVEEVNQILRDIADRTNLLALNASIEAARAGEHGRGFAVVAQEVAKLADSAQENASLISKIITQAAKQIVSGN
TAAYETKEKMGIQDKSFGILVSNLSDLKIRVEKQTSIHKSFLNSFQELFSLSKQLEVLASEQKTGTQEMSRALVSIEQSA
SSLASNTSHLRENVDGLSKQSQRLANHI

Sequences:

>Translated_508_residues
MIANTIRISFAIVMLSINIFFMVAIPTTEKTMSLILSFLELIVLSYGVYTFWLYKKQKFFLKFAYVSIILDIIIYSSVFA
IVVIMSKTPAEKVSIATLPFVMLVLLFVVIYSGFLLSYRLTMTVGYIAISSLLLYVFLGVKGGAEIKFIATAANQFGIPF
IGINTIALICGVHMMSAVVKFMSNSSIEATKSAEEARLKSESANQTKQNIQQEAETLNQSVQEMLKFMDSLNTEIQTQVS
SVEEISASMEELAASMDSASDFVKSQFTRIDDLNQESSVMDKILSEVYSSTINLAQTTDESKQYSVQVTTAMDSVSSNFE
EIKESFQKVEEVNQILRDIADRTNLLALNASIEAARAGEHGRGFAVVAQEVAKLADSAQENASLISKIITQAAKQIVSGN
TAAYETKEKMGIQDKSFGILVSNLSDLKIRVEKQTSIHKSFLNSFQELFSLSKQLEVLASEQKTGTQEMSRALVSIEQSA
SSLASNTSHLRENVDGLSKQSQRLANHI
>Mature_508_residues
MIANTIRISFAIVMLSINIFFMVAIPTTEKTMSLILSFLELIVLSYGVYTFWLYKKQKFFLKFAYVSIILDIIIYSSVFA
IVVIMSKTPAEKVSIATLPFVMLVLLFVVIYSGFLLSYRLTMTVGYIAISSLLLYVFLGVKGGAEIKFIATAANQFGIPF
IGINTIALICGVHMMSAVVKFMSNSSIEATKSAEEARLKSESANQTKQNIQQEAETLNQSVQEMLKFMDSLNTEIQTQVS
SVEEISASMEELAASMDSASDFVKSQFTRIDDLNQESSVMDKILSEVYSSTINLAQTTDESKQYSVQVTTAMDSVSSNFE
EIKESFQKVEEVNQILRDIADRTNLLALNASIEAARAGEHGRGFAVVAQEVAKLADSAQENASLISKIITQAAKQIVSGN
TAAYETKEKMGIQDKSFGILVSNLSDLKIRVEKQTSIHKSFLNSFQELFSLSKQLEVLASEQKTGTQEMSRALVSIEQSA
SSLASNTSHLRENVDGLSKQSQRLANHI

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=199, Percent_Identity=33.6683417085427, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1788195, Length=191, Percent_Identity=30.3664921465969, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI2367378, Length=248, Percent_Identity=29.0322580645161, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788194, Length=194, Percent_Identity=29.3814432989691, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787690, Length=191, Percent_Identity=31.413612565445, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 56043; Mature: 56043

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIANTIRISFAIVMLSINIFFMVAIPTTEKTMSLILSFLELIVLSYGVYTFWLYKKQKFF
CCCCHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKFAYVSIILDIIIYSSVFAIVVIMSKTPAEKVSIATLPFVMLVLLFVVIYSGFLLSYRL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TMTVGYIAISSLLLYVFLGVKGGAEIKFIATAANQFGIPFIGINTIALICGVHMMSAVVK
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECHHCCCCEEHHHHHHHHHHHHHHHHHHH
FMSNSSIEATKSAEEARLKSESANQTKQNIQQEAETLNQSVQEMLKFMDSLNTEIQTQVS
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
SVEEISASMEELAASMDSASDFVKSQFTRIDDLNQESSVMDKILSEVYSSTINLAQTTDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
SKQYSVQVTTAMDSVSSNFEEIKESFQKVEEVNQILRDIADRTNLLALNASIEAARAGEH
CHHEEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHCCCC
GRGFAVVAQEVAKLADSAQENASLISKIITQAAKQIVSGNTAAYETKEKMGIQDKSFGIL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCE
VSNLSDLKIRVEKQTSIHKSFLNSFQELFSLSKQLEVLASEQKTGTQEMSRALVSIEQSA
EECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
SSLASNTSHLRENVDGLSKQSQRLANHI
HHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIANTIRISFAIVMLSINIFFMVAIPTTEKTMSLILSFLELIVLSYGVYTFWLYKKQKFF
CCCCHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKFAYVSIILDIIIYSSVFAIVVIMSKTPAEKVSIATLPFVMLVLLFVVIYSGFLLSYRL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TMTVGYIAISSLLLYVFLGVKGGAEIKFIATAANQFGIPFIGINTIALICGVHMMSAVVK
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECHHCCCCEEHHHHHHHHHHHHHHHHHHH
FMSNSSIEATKSAEEARLKSESANQTKQNIQQEAETLNQSVQEMLKFMDSLNTEIQTQVS
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
SVEEISASMEELAASMDSASDFVKSQFTRIDDLNQESSVMDKILSEVYSSTINLAQTTDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
SKQYSVQVTTAMDSVSSNFEEIKESFQKVEEVNQILRDIADRTNLLALNASIEAARAGEH
CHHEEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHCCCC
GRGFAVVAQEVAKLADSAQENASLISKIITQAAKQIVSGNTAAYETKEKMGIQDKSFGIL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCE
VSNLSDLKIRVEKQTSIHKSFLNSFQELFSLSKQLEVLASEQKTGTQEMSRALVSIEQSA
EECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
SSLASNTSHLRENVDGLSKQSQRLANHI
HHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]