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The map label for this gene is apxID [H]

Identifier: 183219781

GI number: 183219781

Start: 360432

End: 361535

Strand: Direct

Name: apxID [H]

Synonym: LEPBI_I0358

Alternate gene names: 183219781

Gene position: 360432-361535 (Clockwise)

Preceding gene: 183219780

Following gene: 183219782

Centisome position: 10.01

GC content: 34.06

Gene sequence:

>1104_bases
ATGTTTAAAAAGTTTAAAAATATAAAAGAAACTGATTCCAATTGGGAATCAAGACATTCCGCTTCCTATTATGATGAATT
ATTGAAACACCCTGCACCTAACTGGGAAAAGAAGGGAATCTACCTAATCGCCATATTCTTTTTTTGTTTTGTTTTATTTT
TGATGATTGGGCGTGTCGATGTTGTCGTGCAGGCAAATGGTAATATAAGACCCAAAGGGAATTACCATGTTGTAGAAGCA
TTGGAGACGGGAACATTAACGAATTTGTATGTGAAATCAGGGGATTTTCTAAAAAAAGGTGATCCCATTATGGAGTTAGA
ATTCTCCGAACAACAAATCGAATTATCCAAAGATACAAACAATTTAGATTATGAAGAAAAAAAATTACAAAGACTCATTC
GAAATAAAAGAGAAGCGGATAAAATTTTAAAAAATCTTGCTTATAATTTAGAAAACAATTCTGGTTCCTCACTCTCCGGC
GGTGTTTTGAGTAAATTTGTAAGTTTAAAAAAAGCATTTATGGATTTTCAAAATGGAGTGGGAGCCAAATTCATTTACGA
CCAAAGTTTATTAGAATTTAATGAAGAGTTTGGAAATCTAAAAGATGAAATCCAACGTGAAGAGAATATCATAGCGAGTT
TACGTGGAGATACAAAATTAAAAAAGGAAAGAGTTGCGAATGCTGTGATTCGAATGCCTTTTTCAGGCGTGATTGGAGAA
TTGGCCGTCAATAACGTCGGGCAAAATATCATACGAGGCCAGACTGTTGCATCGTTAATGGAAGAAGGCCAACCATTAGA
AGCCATCGTTGAAGTAAGTAGTAAAGATATCGGGGCCGTAAAAATCGGTTTATCGGCTGTGATTAAAGTCAAAGCCTTCC
ATCAAAATGATTTTGGAGTTGTGGAAGGTACTGTTTCACAAATCATTCCAAATACAAAAGAGAAAGATTCTTTTTCAGTG
ATTCTTATTTTAGGAACACAAGATCTAAACCAAGACGGAAAACAATTTCAACTTTTTCCAGGTCTTAAAGTGGTTGCTGA
TATCGTCATTGATCGAAAAAATATTTATCAAATTTTATTTCGATATGCTGATCCTAGGAATTAA

Upstream 100 bases:

>100_bases
GATGAAGGACGCATTGTTGAAATGGGTAATCACGCGGAATTAATCCAAACTAAAGGATATTATTATCATTTGTTTCCTAC
GTTAACGGAAGAGGAAAGCC

Downstream 100 bases:

>100_bases
ATTTGAAACAAAAATTAAAAGATATTTCAGATTCAATTAAAGAAGATGGTTTTTTATCTCAACTCTCTTCGGCAGATCTG
AAAAAATTAATTTCACTTTT

Product: putative associated RTX toxin transporter

Products: NA

Alternate protein names: APX-ID; Cytolysin ID; CLY-ID; HLY-ID; Toxin RTX-I secretion protein D [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MFKKFKNIKETDSNWESRHSASYYDELLKHPAPNWEKKGIYLIAIFFFCFVLFLMIGRVDVVVQANGNIRPKGNYHVVEA
LETGTLTNLYVKSGDFLKKGDPIMELEFSEQQIELSKDTNNLDYEEKKLQRLIRNKREADKILKNLAYNLENNSGSSLSG
GVLSKFVSLKKAFMDFQNGVGAKFIYDQSLLEFNEEFGNLKDEIQREENIIASLRGDTKLKKERVANAVIRMPFSGVIGE
LAVNNVGQNIIRGQTVASLMEEGQPLEAIVEVSSKDIGAVKIGLSAVIKVKAFHQNDFGVVEGTVSQIIPNTKEKDSFSV
ILILGTQDLNQDGKQFQLFPGLKVVADIVIDRKNIYQILFRYADPRN

Sequences:

>Translated_367_residues
MFKKFKNIKETDSNWESRHSASYYDELLKHPAPNWEKKGIYLIAIFFFCFVLFLMIGRVDVVVQANGNIRPKGNYHVVEA
LETGTLTNLYVKSGDFLKKGDPIMELEFSEQQIELSKDTNNLDYEEKKLQRLIRNKREADKILKNLAYNLENNSGSSLSG
GVLSKFVSLKKAFMDFQNGVGAKFIYDQSLLEFNEEFGNLKDEIQREENIIASLRGDTKLKKERVANAVIRMPFSGVIGE
LAVNNVGQNIIRGQTVASLMEEGQPLEAIVEVSSKDIGAVKIGLSAVIKVKAFHQNDFGVVEGTVSQIIPNTKEKDSFSV
ILILGTQDLNQDGKQFQLFPGLKVVADIVIDRKNIYQILFRYADPRN
>Mature_367_residues
MFKKFKNIKETDSNWESRHSASYYDELLKHPAPNWEKKGIYLIAIFFFCFVLFLMIGRVDVVVQANGNIRPKGNYHVVEA
LETGTLTNLYVKSGDFLKKGDPIMELEFSEQQIELSKDTNNLDYEEKKLQRLIRNKREADKILKNLAYNLENNSGSSLSG
GVLSKFVSLKKAFMDFQNGVGAKFIYDQSLLEFNEEFGNLKDEIQREENIIASLRGDTKLKKERVANAVIRMPFSGVIGE
LAVNNVGQNIIRGQTVASLMEEGQPLEAIVEVSSKDIGAVKIGLSAVIKVKAFHQNDFGVVEGTVSQIIPNTKEKDSFSV
ILILGTQDLNQDGKQFQLFPGLKVVADIVIDRKNIYQILFRYADPRN

Specific function: Involved in the transport of the toxin RTX-I as well as that of RTX-II [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41443; Mature: 41443

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKKFKNIKETDSNWESRHSASYYDELLKHPAPNWEKKGIYLIAIFFFCFVLFLMIGRVD
CCCHHCCCHHCCCCHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEE
VVVQANGNIRPKGNYHVVEALETGTLTNLYVKSGDFLKKGDPIMELEFSEQQIELSKDTN
EEEECCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCEEEEECCCHHEEECCCCC
NLDYEEKKLQRLIRNKREADKILKNLAYNLENNSGSSLSGGVLSKFVSLKKAFMDFQNGV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
GAKFIYDQSLLEFNEEFGNLKDEIQREENIIASLRGDTKLKKERVANAVIRMPFSGVIGE
CCEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHH
LAVNNVGQNIIRGQTVASLMEEGQPLEAIVEVSSKDIGAVKIGLSAVIKVKAFHQNDFGV
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEEECHHHEEEEEEECCCCCCH
VEGTVSQIIPNTKEKDSFSVILILGTQDLNQDGKQFQLFPGLKVVADIVIDRKNIYQILF
HHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCEEEECCCHHHHHHHHHCHHHHHHHHH
RYADPRN
HHCCCCC
>Mature Secondary Structure
MFKKFKNIKETDSNWESRHSASYYDELLKHPAPNWEKKGIYLIAIFFFCFVLFLMIGRVD
CCCHHCCCHHCCCCHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEE
VVVQANGNIRPKGNYHVVEALETGTLTNLYVKSGDFLKKGDPIMELEFSEQQIELSKDTN
EEEECCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCEEEEECCCHHEEECCCCC
NLDYEEKKLQRLIRNKREADKILKNLAYNLENNSGSSLSGGVLSKFVSLKKAFMDFQNGV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
GAKFIYDQSLLEFNEEFGNLKDEIQREENIIASLRGDTKLKKERVANAVIRMPFSGVIGE
CCEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHH
LAVNNVGQNIIRGQTVASLMEEGQPLEAIVEVSSKDIGAVKIGLSAVIKVKAFHQNDFGV
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEEECHHHEEEEEEECCCCCCH
VEGTVSQIIPNTKEKDSFSVILILGTQDLNQDGKQFQLFPGLKVVADIVIDRKNIYQILF
HHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCEEEECCCHHHHHHHHHCHHHHHHHHH
RYADPRN
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1860823; 1937809; 8181764 [H]