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The map label for this gene is aroH [H]

Identifier: 183219696

GI number: 183219696

Start: 265448

End: 266497

Strand: Reverse

Name: aroH [H]

Synonym: LEPBI_I0272

Alternate gene names: 183219696

Gene position: 266497-265448 (Counterclockwise)

Preceding gene: 183219697

Following gene: 183219692

Centisome position: 7.4

GC content: 41.9

Gene sequence:

>1050_bases
ATGAAACCAACAGCAAACTTAAGAATATTAGAACAACATAGCCTCATCCCTCCTTCTGTCATCATGGAAGAGCTTCCCCT
CACTGATGAAGCCTCTGACGTTGTGGTGAGAACCAGAAGTGAAATATCGGATATCATTCATGGGAAAGACGAGAAACGCA
TGTTAGTTGTCGTTGGTCCATGTTCTGTTCACGACATTGGTGCCGTGATGGAATACGCTGAAAAATTAAAACCAAAAATC
AAAGAATTTCAAAAAGAACTCCTCATTGTGATGCGAGTCTATTTTGAAAAACCTAGGACCACTGTGGGTTGGAAAGGACT
CATCAATGATCCTGATTTAGATGGTTCGTTTCATATCAACAAAGGTTTACAACTCGCAAGGAAACTTTTACTCGACCTAA
ATAAAATGGGAATCCCATGTGGAACAGAATTTTTAGATGTCATCTCTCCGCAATACATCGCAGACCTCGTGGCATGGGGT
GCCATTGGAGCAAGGACAACAGAAAGCCAAGTCCACAGAGAATTGGCATCTGGGCTTTCCGCACCCATTGGTTTCAAAAA
TGGAACGGATGGAAATGTACAAATTGCTGTTGATGCCATTCGTTCTGCAAGTTCCAGCCACCATTTCCTTTCTGTTACCA
ACCAAGGAAGTAGTGCCATTTTTCGAACAGCAGGAAACAAAGACACACATGTGATTTTACGTGGTGGAAACAAAGGACCT
AACTTTGATGAGGCGTCTGTCAATGACGTGGGATCTCAAATCGAAAAAGCTGGACTTCCCCCAAAAGTGATGGTGGATTG
TTCTCATGGTAATAGCCAAAAAGATTTTCGAAAACAACCAGGTGTAGTGGATTCCGTTGCAGAACAATTTGCCAAAGGGA
GCAAATACATTTTAGGTGTGATGATTGAAAGCCACTTAAAAGAAGGAAACCAATCCATTGATGCCAAACCTTTGACATAT
GGACAATCCATCACCGATGCTTGTGTGTCTTGGGAAACAACAGTTCCAATGCTTGAAAAACTAGCAGAAGCCGCAAACAA
ACGAAAATAA

Upstream 100 bases:

>100_bases
GGATTTTGGCGCAAGCGGGATTTAAGTCTTACAAAAACGTAGCTGGCGGAACATTAGCCTATTCCGATTTAGTGGACCCA
AACATGCAGAAGTATTAATT

Downstream 100 bases:

>100_bases
ACCAATCTAACAAAGGATTGGTTCGATCCCAATCTCTTCCATAAGAGGGTGTCAAAACCCTCTCATTTCACTCTGACGAC
GAGTTGATTTTTCTAATGGA

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MKPTANLRILEQHSLIPPSVIMEELPLTDEASDVVVRTRSEISDIIHGKDEKRMLVVVGPCSVHDIGAVMEYAEKLKPKI
KEFQKELLIVMRVYFEKPRTTVGWKGLINDPDLDGSFHINKGLQLARKLLLDLNKMGIPCGTEFLDVISPQYIADLVAWG
AIGARTTESQVHRELASGLSAPIGFKNGTDGNVQIAVDAIRSASSSHHFLSVTNQGSSAIFRTAGNKDTHVILRGGNKGP
NFDEASVNDVGSQIEKAGLPPKVMVDCSHGNSQKDFRKQPGVVDSVAEQFAKGSKYILGVMIESHLKEGNQSIDAKPLTY
GQSITDACVSWETTVPMLEKLAEAANKRK

Sequences:

>Translated_349_residues
MKPTANLRILEQHSLIPPSVIMEELPLTDEASDVVVRTRSEISDIIHGKDEKRMLVVVGPCSVHDIGAVMEYAEKLKPKI
KEFQKELLIVMRVYFEKPRTTVGWKGLINDPDLDGSFHINKGLQLARKLLLDLNKMGIPCGTEFLDVISPQYIADLVAWG
AIGARTTESQVHRELASGLSAPIGFKNGTDGNVQIAVDAIRSASSSHHFLSVTNQGSSAIFRTAGNKDTHVILRGGNKGP
NFDEASVNDVGSQIEKAGLPPKVMVDCSHGNSQKDFRKQPGVVDSVAEQFAKGSKYILGVMIESHLKEGNQSIDAKPLTY
GQSITDACVSWETTVPMLEKLAEAANKRK
>Mature_349_residues
MKPTANLRILEQHSLIPPSVIMEELPLTDEASDVVVRTRSEISDIIHGKDEKRMLVVVGPCSVHDIGAVMEYAEKLKPKI
KEFQKELLIVMRVYFEKPRTTVGWKGLINDPDLDGSFHINKGLQLARKLLLDLNKMGIPCGTEFLDVISPQYIADLVAWG
AIGARTTESQVHRELASGLSAPIGFKNGTDGNVQIAVDAIRSASSSHHFLSVTNQGSSAIFRTAGNKDTHVILRGGNKGP
NFDEASVNDVGSQIEKAGLPPKVMVDCSHGNSQKDFRKQPGVVDSVAEQFAKGSKYILGVMIESHLKEGNQSIDAKPLTY
GQSITDACVSWETTVPMLEKLAEAANKRK

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786969, Length=345, Percent_Identity=57.9710144927536, Blast_Score=412, Evalue=1e-116,
Organism=Escherichia coli, GI1787996, Length=349, Percent_Identity=51.8624641833811, Blast_Score=377, Evalue=1e-106,
Organism=Escherichia coli, GI1788953, Length=343, Percent_Identity=52.1865889212828, Blast_Score=375, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6319726, Length=347, Percent_Identity=55.3314121037464, Blast_Score=385, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6320240, Length=356, Percent_Identity=50.2808988764045, Blast_Score=374, Evalue=1e-104,

Paralogues:

None

Copy number: 600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38064; Mature: 38064

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPTANLRILEQHSLIPPSVIMEELPLTDEASDVVVRTRSEISDIIHGKDEKRMLVVVGP
CCCCCCEEEECCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECC
CSVHDIGAVMEYAEKLKPKIKEFQKELLIVMRVYFEKPRTTVGWKGLINDPDLDGSFHIN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEC
KGLQLARKLLLDLNKMGIPCGTEFLDVISPQYIADLVAWGAIGARTTESQVHRELASGLS
HHHHHHHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
APIGFKNGTDGNVQIAVDAIRSASSSHHFLSVTNQGSSAIFRTAGNKDTHVILRGGNKGP
CCCCCCCCCCCCEEEEEHHHHCCCCCCEEEEEECCCCCEEEEECCCCCCEEEEECCCCCC
NFDEASVNDVGSQIEKAGLPPKVMVDCSHGNSQKDFRKQPGVVDSVAEQFAKGSKYILGV
CCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHCCCHHHHHHHHHHCCCCEEHHH
MIESHLKEGNQSIDAKPLTYGQSITDACVSWETTVPMLEKLAEAANKRK
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKPTANLRILEQHSLIPPSVIMEELPLTDEASDVVVRTRSEISDIIHGKDEKRMLVVVGP
CCCCCCEEEECCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECC
CSVHDIGAVMEYAEKLKPKIKEFQKELLIVMRVYFEKPRTTVGWKGLINDPDLDGSFHIN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEC
KGLQLARKLLLDLNKMGIPCGTEFLDVISPQYIADLVAWGAIGARTTESQVHRELASGLS
HHHHHHHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
APIGFKNGTDGNVQIAVDAIRSASSSHHFLSVTNQGSSAIFRTAGNKDTHVILRGGNKGP
CCCCCCCCCCCCEEEEEHHHHCCCCCCEEEEEECCCCCEEEEECCCCCCEEEEECCCCCC
NFDEASVNDVGSQIEKAGLPPKVMVDCSHGNSQKDFRKQPGVVDSVAEQFAKGSKYILGV
CCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHCCCHHHHHHHHHHCCCCEEHHH
MIESHLKEGNQSIDAKPLTYGQSITDACVSWETTVPMLEKLAEAANKRK
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]