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The map label for this gene is 183219670

Identifier: 183219670

GI number: 183219670

Start: 235123

End: 236541

Strand: Reverse

Name: 183219670

Synonym: LEPBI_I0245

Alternate gene names: NA

Gene position: 236541-235123 (Counterclockwise)

Preceding gene: 183219671

Following gene: 183219669

Centisome position: 6.57

GC content: 42.57

Gene sequence:

>1419_bases
ATGGCACTTCCCAAAGTATGTGTAGTTGGAGCTGGTTCATCTGGAATCACCGTCATCAAATCGTTAAAGGAACATGGCAT
CCCCTTTGATTGTTATGAAAAGGGAAGTGATGTCGGTGGCAACTGGCGATACAAAAATGACAACGGTCTCAGTAATATTT
ATAAATCATTACACATCAATACCCATCGGGATCGGATGGAATACCGTGACTTTCCCATGCCAACAAATTACCCTGACTAC
CCCAATCACGAACCCATCCAACAATACTTTTTAGCCTATGTGGACCACTTCGGACTTCGCAAACACATCCAATTCAAAAA
CGGAGTGAAAAAAGCAGAACGAACAGAAGAAGGACTTTGGAGGATCACACCCGAAAAAGGACCCACACAAACCTATGATG
TGCTCGTGGTTGCAAACGGCCACCATTGGAGTGAACGTTGGCCTGACCCACCATTCCCTGGAAAATTTTCTGGTCAAACC
ATCCACTCTCATTCCTATGTTGACCCAAAAACACCAGTTAACTGCGAAGGGAAAAACGTTGTGATACTTGGTATGGGAAA
CAGTGCCATGGACATCTCGGTTGAGCTGTCGAGACCAGGTGTTGCCAAAAAAGTATTTTTATCTGCAAGAAGAGGGGCTT
ACGTCATTCCGAATTATTTATTTGGAAAACCATTAGACAAACTCACAGAATACACACCACATTGGGTTCCTTTTTTCATC
CAACAAACACTCGCTCACCTACTCATCCGATTTGGTGTGGGAAAAATGGAAGACTTTGGTCTTCCAAAACCAGATCATAA
ATTTGGTTCTGCTCACCCCACCATTTCCCAAGATTTACTCGTGAGACTTGGTCGAGGGGACATCAAACCAAAACCTGTCA
TCACAGAACTCCGTGGCAAAAAAATTGCCTTTGCTGATGGGACCGAGGAAGAGGCAGATGTTCTCATTTACTGCACAGGA
TATAATATCAAATTTCCATTTTTTGAAGAAGATTTGATTTCTGCACCTAACAATTACATTCCACTTTATTATAAAATGAT
GAAACCAGGAATCAACAATTTGTTTTTCGTGGGCCTTATGCAACCGTTAGGTGCCATTATGCCTCTTGCGGAATGCCAAG
GCAAATGGATCGCACAATACTTAACAGGGAATTATGTTCTGCCTTCTAAGGAAGAGATGGAGACCTCGATTTCAAAAGAT
GAAAAGGCGATGAAAAAAAGGTATGTGAGTAGCACAAGGCATACCATCCAAGTGGACTATGATAGTTTTTTGTACGAGAT
GAAAAGGGAAATGGAACGAGGCAAAAAAAAGGCAATGCAGGAAGGAAACCATTTGCCAATCGAAGCGCGTGCTATGTACC
ATTCAGAGAAGAGTCATGTCCCGTCGTCCCGCAAACAAAAACAATTGGTTTCGAAGTAA

Upstream 100 bases:

>100_bases
TTTTTCAAAATAGTCCCAAAATCTTCTTGATAACGATGTTCGCTATTCTATAACTCTTTCCCAAACGTTCATCGAATCTT
TAGTAAGAGAGAAACCCATT

Downstream 100 bases:

>100_bases
AACAATCATATTTCTGTTTCACACAATCAGTATCCTAGGATTAGGATCTGGTTGTGTTTCCAGAGGGTATTCCTACCAGG
GCAATCCTCTCTTTGGTTGG

Product: putative dimethylaniline monooxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MALPKVCVVGAGSSGITVIKSLKEHGIPFDCYEKGSDVGGNWRYKNDNGLSNIYKSLHINTHRDRMEYRDFPMPTNYPDY
PNHEPIQQYFLAYVDHFGLRKHIQFKNGVKKAERTEEGLWRITPEKGPTQTYDVLVVANGHHWSERWPDPPFPGKFSGQT
IHSHSYVDPKTPVNCEGKNVVILGMGNSAMDISVELSRPGVAKKVFLSARRGAYVIPNYLFGKPLDKLTEYTPHWVPFFI
QQTLAHLLIRFGVGKMEDFGLPKPDHKFGSAHPTISQDLLVRLGRGDIKPKPVITELRGKKIAFADGTEEEADVLIYCTG
YNIKFPFFEEDLISAPNNYIPLYYKMMKPGINNLFFVGLMQPLGAIMPLAECQGKWIAQYLTGNYVLPSKEEMETSISKD
EKAMKKRYVSSTRHTIQVDYDSFLYEMKREMERGKKKAMQEGNHLPIEARAMYHSEKSHVPSSRKQKQLVSK

Sequences:

>Translated_472_residues
MALPKVCVVGAGSSGITVIKSLKEHGIPFDCYEKGSDVGGNWRYKNDNGLSNIYKSLHINTHRDRMEYRDFPMPTNYPDY
PNHEPIQQYFLAYVDHFGLRKHIQFKNGVKKAERTEEGLWRITPEKGPTQTYDVLVVANGHHWSERWPDPPFPGKFSGQT
IHSHSYVDPKTPVNCEGKNVVILGMGNSAMDISVELSRPGVAKKVFLSARRGAYVIPNYLFGKPLDKLTEYTPHWVPFFI
QQTLAHLLIRFGVGKMEDFGLPKPDHKFGSAHPTISQDLLVRLGRGDIKPKPVITELRGKKIAFADGTEEEADVLIYCTG
YNIKFPFFEEDLISAPNNYIPLYYKMMKPGINNLFFVGLMQPLGAIMPLAECQGKWIAQYLTGNYVLPSKEEMETSISKD
EKAMKKRYVSSTRHTIQVDYDSFLYEMKREMERGKKKAMQEGNHLPIEARAMYHSEKSHVPSSRKQKQLVSK
>Mature_471_residues
ALPKVCVVGAGSSGITVIKSLKEHGIPFDCYEKGSDVGGNWRYKNDNGLSNIYKSLHINTHRDRMEYRDFPMPTNYPDYP
NHEPIQQYFLAYVDHFGLRKHIQFKNGVKKAERTEEGLWRITPEKGPTQTYDVLVVANGHHWSERWPDPPFPGKFSGQTI
HSHSYVDPKTPVNCEGKNVVILGMGNSAMDISVELSRPGVAKKVFLSARRGAYVIPNYLFGKPLDKLTEYTPHWVPFFIQ
QTLAHLLIRFGVGKMEDFGLPKPDHKFGSAHPTISQDLLVRLGRGDIKPKPVITELRGKKIAFADGTEEEADVLIYCTGY
NIKFPFFEEDLISAPNNYIPLYYKMMKPGINNLFFVGLMQPLGAIMPLAECQGKWIAQYLTGNYVLPSKEEMETSISKDE
KAMKKRYVSSTRHTIQVDYDSFLYEMKREMERGKKKAMQEGNHLPIEARAMYHSEKSHVPSSRKQKQLVSK

Specific function: Unknown

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI221316672, Length=446, Percent_Identity=38.1165919282511, Blast_Score=270, Evalue=2e-72,
Organism=Homo sapiens, GI4503757, Length=455, Percent_Identity=33.1868131868132, Blast_Score=248, Evalue=8e-66,
Organism=Homo sapiens, GI221316674, Length=425, Percent_Identity=37.1764705882353, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI50541965, Length=445, Percent_Identity=33.0337078651685, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI50541961, Length=445, Percent_Identity=33.0337078651685, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI4503759, Length=441, Percent_Identity=31.7460317460317, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI4503755, Length=449, Percent_Identity=29.8440979955457, Blast_Score=193, Evalue=4e-49,
Organism=Homo sapiens, GI221316678, Length=283, Percent_Identity=35.6890459363958, Blast_Score=149, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI25145785, Length=441, Percent_Identity=33.7868480725624, Blast_Score=279, Evalue=3e-75,
Organism=Caenorhabditis elegans, GI25150462, Length=451, Percent_Identity=35.920177383592, Blast_Score=264, Evalue=8e-71,
Organism=Caenorhabditis elegans, GI17541300, Length=448, Percent_Identity=34.375, Blast_Score=251, Evalue=8e-67,
Organism=Caenorhabditis elegans, GI17561948, Length=449, Percent_Identity=34.5211581291759, Blast_Score=231, Evalue=6e-61,
Organism=Caenorhabditis elegans, GI17555726, Length=449, Percent_Identity=34.7438752783964, Blast_Score=222, Evalue=4e-58,
Organism=Caenorhabditis elegans, GI193202226, Length=397, Percent_Identity=27.455919395466, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17506045, Length=215, Percent_Identity=30.2325581395349, Blast_Score=99, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6321970, Length=198, Percent_Identity=28.7878787878788, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19922866, Length=218, Percent_Identity=29.8165137614679, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI19921694, Length=216, Percent_Identity=28.2407407407407, Blast_Score=96, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: NA

Molecular weight: Translated: 53827; Mature: 53695

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALPKVCVVGAGSSGITVIKSLKEHGIPFDCYEKGSDVGGNWRYKNDNGLSNIYKSLHIN
CCCCCEEEEECCCCCHHHHHHHHHCCCCEEHHHCCCCCCCCEEECCCCCHHHHHHHHCCC
THRDRMEYRDFPMPTNYPDYPNHEPIQQYFLAYVDHFGLRKHIQFKNGVKKAERTEEGLW
CCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
RITPEKGPTQTYDVLVVANGHHWSERWPDPPFPGKFSGQTIHSHSYVDPKTPVNCEGKNV
EECCCCCCCCEEEEEEEECCCCCHHCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCEE
VILGMGNSAMDISVELSRPGVAKKVFLSARRGAYVIPNYLFGKPLDKLTEYTPHWVPFFI
EEEECCCCCEEEEEEECCCCCHHHHHHHHCCCCEECCCHHHCCCHHHHHHCCCCHHHHHH
QQTLAHLLIRFGVGKMEDFGLPKPDHKFGSAHPTISQDLLVRLGRGDIKPKPVITELRGK
HHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHCCCC
KIAFADGTEEEADVLIYCTGYNIKFPFFEEDLISAPNNYIPLYYKMMKPGINNLFFVGLM
EEEECCCCCCCCCEEEEEECCCEECCCCHHHHHCCCCCCEEEEHEECCCCCCCEEHHHHH
QPLGAIMPLAECQGKWIAQYLTGNYVLPSKEEMETSISKDEKAMKKRYVSSTRHTIQVDY
HHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECH
DSFLYEMKREMERGKKKAMQEGNHLPIEARAMYHSEKSHVPSSRKQKQLVSK
HHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHCCHHHCCCCHHHHHHHHCC
>Mature Secondary Structure 
ALPKVCVVGAGSSGITVIKSLKEHGIPFDCYEKGSDVGGNWRYKNDNGLSNIYKSLHIN
CCCCEEEEECCCCCHHHHHHHHHCCCCEEHHHCCCCCCCCEEECCCCCHHHHHHHHCCC
THRDRMEYRDFPMPTNYPDYPNHEPIQQYFLAYVDHFGLRKHIQFKNGVKKAERTEEGLW
CCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
RITPEKGPTQTYDVLVVANGHHWSERWPDPPFPGKFSGQTIHSHSYVDPKTPVNCEGKNV
EECCCCCCCCEEEEEEEECCCCCHHCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCEE
VILGMGNSAMDISVELSRPGVAKKVFLSARRGAYVIPNYLFGKPLDKLTEYTPHWVPFFI
EEEECCCCCEEEEEEECCCCCHHHHHHHHCCCCEECCCHHHCCCHHHHHHCCCCHHHHHH
QQTLAHLLIRFGVGKMEDFGLPKPDHKFGSAHPTISQDLLVRLGRGDIKPKPVITELRGK
HHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHCCCC
KIAFADGTEEEADVLIYCTGYNIKFPFFEEDLISAPNNYIPLYYKMMKPGINNLFFVGLM
EEEECCCCCCCCCEEEEEECCCEECCCCHHHHHCCCCCCEEEEHEECCCCCCCEEHHHHH
QPLGAIMPLAECQGKWIAQYLTGNYVLPSKEEMETSISKDEKAMKKRYVSSTRHTIQVDY
HHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECH
DSFLYEMKREMERGKKKAMQEGNHLPIEARAMYHSEKSHVPSSRKQKQLVSK
HHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHCCHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]