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The map label for this gene is qor [H]

Identifier: 183219617

GI number: 183219617

Start: 186529

End: 187527

Strand: Reverse

Name: qor [H]

Synonym: LEPBI_I0192

Alternate gene names: 183219617

Gene position: 187527-186529 (Counterclockwise)

Preceding gene: 183219625

Following gene: 183219616

Centisome position: 5.21

GC content: 40.84

Gene sequence:

>999_bases
ATGAGTGAATGGGATGAGATGAAAGCAGTCACCATTCTCAAATACGATGAATCCGAACCACAATTGGAACTCCGTGAAAA
AGAAATTCCAACCCCGAAAGAGAACGAAGTAAGGATCAAAATCCACCTTTCGCCCATCAATCCATCTGACCTAATGTTCA
TTCGTGGATTGTACGGATTCAAAAAAAAGGCACCTGTTTCTGCAGGATTTGAAGCGAGTGGGATCGTGGATGCAGTCGGA
TCAGGAATCAAAACACTCAAAGTGGGAATGTCTGTCTCTTGTGTTGCCCCACAAAATGATGGGTCTTGGGCCGAATATAT
GATCACAACAGAAGACAACTGTTTGCCGTTAGTGGATGGTGTCACACTGGACGAAGGATCTAGTTTTTTTGTAAACCCAA
TGACCGCCTGGGCGATGGTCTCTCGTTGCCAAAAAGAAGGACATGGAGCCATGATCCAAACTGCCGCCGCAAGTGCCCTT
GGCAAAATGGTGGTTCGCCTCTGCAAAGAAAAAGGAATCCCTCTAATCAATGTTGTGCGAAAAAAAGAACAAGAGGATAA
CCTTTTGGCCATTGGAGCAGAAAATATTCTCAACTCCTCTTCTCCCAACTACCAAAAAGATTTATATAAAATTTCTAAAA
AGCTAAATGCAACTTATGCAATCGATGCAGTGGCCGGAGAAACAGCACAATCCCTTGTGGAATGTATGCCTTATGGATCA
AAAATTGTTTGTTACGGTGCGTTGTCAGAAAAACCATTTGCGGTCAATGCTGGAATCATGTTGTTTCAGAACAAAAAGAT
CGAAGGTTTTTGGTTATCCTCTTGGATCTATGAAATAGGATTGGAAGAGTTTCAAAAACAAGCAAAAGAAGCACAGACGT
ATTTAAAAACAGTTTTCCAAACCAAAATCAACAAACGATTTAAGTTTGAAGATTTTAAAGAAGGATTAGAATTTTATAAA
CAACACATGACAGAAGGGAAGGTAGTCTTTGGTCCGTAA

Upstream 100 bases:

>100_bases
AAAATGATACCTGTGATGGTTTCGTTGTTTATTTTTTTTGATTTCACGGGGGACTCAAAGTAATTTCCTTCAAAAGAAAG
AGTTGGCAAGCAGATTTTAC

Downstream 100 bases:

>100_bases
AAGTTTCCAATTCCTTTGGATCACGGCTTTTGTATCGTTTACAATTTCACATTGTATCAGCGATACCAAAAAAAATTTAG
ATAGTTTAAAGGCGTGTAAG

Product: NADPH:quinone reductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MSEWDEMKAVTILKYDESEPQLELREKEIPTPKENEVRIKIHLSPINPSDLMFIRGLYGFKKKAPVSAGFEASGIVDAVG
SGIKTLKVGMSVSCVAPQNDGSWAEYMITTEDNCLPLVDGVTLDEGSSFFVNPMTAWAMVSRCQKEGHGAMIQTAAASAL
GKMVVRLCKEKGIPLINVVRKKEQEDNLLAIGAENILNSSSPNYQKDLYKISKKLNATYAIDAVAGETAQSLVECMPYGS
KIVCYGALSEKPFAVNAGIMLFQNKKIEGFWLSSWIYEIGLEEFQKQAKEAQTYLKTVFQTKINKRFKFEDFKEGLEFYK
QHMTEGKVVFGP

Sequences:

>Translated_332_residues
MSEWDEMKAVTILKYDESEPQLELREKEIPTPKENEVRIKIHLSPINPSDLMFIRGLYGFKKKAPVSAGFEASGIVDAVG
SGIKTLKVGMSVSCVAPQNDGSWAEYMITTEDNCLPLVDGVTLDEGSSFFVNPMTAWAMVSRCQKEGHGAMIQTAAASAL
GKMVVRLCKEKGIPLINVVRKKEQEDNLLAIGAENILNSSSPNYQKDLYKISKKLNATYAIDAVAGETAQSLVECMPYGS
KIVCYGALSEKPFAVNAGIMLFQNKKIEGFWLSSWIYEIGLEEFQKQAKEAQTYLKTVFQTKINKRFKFEDFKEGLEFYK
QHMTEGKVVFGP
>Mature_331_residues
SEWDEMKAVTILKYDESEPQLELREKEIPTPKENEVRIKIHLSPINPSDLMFIRGLYGFKKKAPVSAGFEASGIVDAVGS
GIKTLKVGMSVSCVAPQNDGSWAEYMITTEDNCLPLVDGVTLDEGSSFFVNPMTAWAMVSRCQKEGHGAMIQTAAASALG
KMVVRLCKEKGIPLINVVRKKEQEDNLLAIGAENILNSSSPNYQKDLYKISKKLNATYAIDAVAGETAQSLVECMPYGSK
IVCYGALSEKPFAVNAGIMLFQNKKIEGFWLSSWIYEIGLEEFQKQAKEAQTYLKTVFQTKINKRFKFEDFKEGLEFYKQ
HMTEGKVVFGP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI67078404, Length=294, Percent_Identity=27.5510204081633, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI67078406, Length=256, Percent_Identity=28.90625, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI24308257, Length=351, Percent_Identity=23.6467236467236, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI194239674, Length=315, Percent_Identity=22.5396825396825, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI13236495, Length=315, Percent_Identity=22.5396825396825, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI194239676, Length=201, Percent_Identity=24.8756218905473, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI18379349, Length=316, Percent_Identity=23.7341772151899, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI22538446, Length=236, Percent_Identity=25.8474576271186, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI22538444, Length=236, Percent_Identity=25.8474576271186, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1790485, Length=232, Percent_Identity=25.8620689655172, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788407, Length=365, Percent_Identity=23.8356164383562, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787863, Length=281, Percent_Identity=26.3345195729537, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17536829, Length=256, Percent_Identity=30.859375, Blast_Score=131, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17556000, Length=292, Percent_Identity=27.0547945205479, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17507255, Length=199, Percent_Identity=26.1306532663317, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6319500, Length=273, Percent_Identity=26.007326007326, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323961, Length=209, Percent_Identity=24.8803827751196, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI45550423, Length=287, Percent_Identity=32.0557491289199, Blast_Score=139, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 36991; Mature: 36860

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEWDEMKAVTILKYDESEPQLELREKEIPTPKENEVRIKIHLSPINPSDLMFIRGLYGF
CCCHHHCCEEEEEEECCCCCCHHHHHCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHCC
KKKAPVSAGFEASGIVDAVGSGIKTLKVGMSVSCVAPQNDGSWAEYMITTEDNCLPLVDG
CCCCCCCCCCCCCCHHHHHCCCCEEEEECCEEEEECCCCCCCEEEEEEECCCCCEEEECC
VTLDEGSSFFVNPMTAWAMVSRCQKEGHGAMIQTAAASALGKMVVRLCKEKGIPLINVVR
EEECCCCCEEECHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCCHHHHHH
KKEQEDNLLAIGAENILNSSSPNYQKDLYKISKKLNATYAIDAVAGETAQSLVECMPYGS
HCCCCCCEEEEEHHHHHCCCCCCHHHHHHHHHHHCCCEEEEEHHCCHHHHHHHHHCCCCC
KIVCYGALSEKPFAVNAGIMLFQNKKIEGFWLSSWIYEIGLEEFQKQAKEAQTYLKTVFQ
EEEEEECCCCCCEEEECCEEEEECCCCCEEHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
TKINKRFKFEDFKEGLEFYKQHMTEGKVVFGP
HHHCCCCCHHHHHHHHHHHHHHCCCCCEEECC
>Mature Secondary Structure 
SEWDEMKAVTILKYDESEPQLELREKEIPTPKENEVRIKIHLSPINPSDLMFIRGLYGF
CCHHHCCEEEEEEECCCCCCHHHHHCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHCC
KKKAPVSAGFEASGIVDAVGSGIKTLKVGMSVSCVAPQNDGSWAEYMITTEDNCLPLVDG
CCCCCCCCCCCCCCHHHHHCCCCEEEEECCEEEEECCCCCCCEEEEEEECCCCCEEEECC
VTLDEGSSFFVNPMTAWAMVSRCQKEGHGAMIQTAAASALGKMVVRLCKEKGIPLINVVR
EEECCCCCEEECHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCCHHHHHH
KKEQEDNLLAIGAENILNSSSPNYQKDLYKISKKLNATYAIDAVAGETAQSLVECMPYGS
HCCCCCCEEEEEHHHHHCCCCCCHHHHHHHHHHHCCCEEEEEHHCCHHHHHHHHHCCCCC
KIVCYGALSEKPFAVNAGIMLFQNKKIEGFWLSSWIYEIGLEEFQKQAKEAQTYLKTVFQ
EEEEEECCCCCCEEEECCEEEEECCCCCEEHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
TKINKRFKFEDFKEGLEFYKQHMTEGKVVFGP
HHHCCCCCHHHHHHHHHHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]