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The map label for this gene is crp [C]

Identifier: 183219593

GI number: 183219593

Start: 163235

End: 164446

Strand: Reverse

Name: crp [C]

Synonym: LEPBI_I0168

Alternate gene names: 183219593

Gene position: 164446-163235 (Counterclockwise)

Preceding gene: 183219594

Following gene: 183219592

Centisome position: 4.57

GC content: 41.5

Gene sequence:

>1212_bases
ATGTCGTTTTTTCAAATGGTTACTTTCCCGGCGAACTCCTACATCATTGTAGAGGGGAAAAAGGATGCGAACAATTTCTA
TATCATCCGCGAGGGAAAAGTACGTGTCACGCGTGAGACGGCTGTTGTCGGAGAAGACCCCAATCAGGTTTTAGGACCTG
GTGACTTTTTCGGTGTAGTGGCGGCGATGAGCCAACACCCTCAAATTGAATCAGCAACTTCCCTTACGAATGTATCGTTA
ATCTCTGTGAGTTACGACCAATTCGGGACTCTCATCCAAAAATCCACAGCTGTGGCAATGAATATCATACGTTTCTTCTC
CATGAAGTTACGACAATTTGATACCACCATCACTCGGTTATCCTTTCGAAACGCAGTAGAAGAAGATCCAAACGAACTGT
TTAAGATTGGGGAATACTACTTCCAACAGCAAAACACGTCTCATGCCACCTTTGCATACCAAAGTTATTTAAAACACCTT
CCCAATGGTCAATTTGTACCGCAGGCAAAACTGCGATTACAAACCATGAACCAAGCATTCCAGTCCGCTCCCATTGATTA
TACAAAATTCAATCGGAACTACAAAGACAGCGAGATGATCTTTTGTGAGCATGAACCTGGTAAGGAATTATTCATTTTAC
AAAGTGGGAAGGTAAAAATTTCCAAAATCGTAAACCAAAATGAAGTGATGCTCGCTGTCCTCCAAGCGGGAGACATTTTT
GGTGAGATGGCAATCCTTGATAACAAACCTCGCTCTGCTTCGGCAGTGGCAGCGGGTGATGTAGAACTACTTGCCATCAA
CAAAGCAAACTTCGAGGGAATGGTAAAAGCACAACCGCAACTGGCCACTCGCCTCATTACCCTTTTATCAGAACGGATTT
GGATTGATTACAAACAATTAGCAAATTTACTTTTGAAAGACCCTCAAGGTCGCATTGTCGATACACTGATGACGTTGGCA
GAAAAAAACCGAATCAAAGTGGCACCCAAACAAGCTTATAATTTTGAAATTGGTACCAAGGACTTACTCAAAATGGTCGG
TCTCACGGATCCGAAAGACGAACTCATCATTTCCGATATCATGAAAAATAATAAATTTATTCGAATGGATATGGGAAAAA
TTGTTTGTTCTGATATGGCAGAGCTAGAAAAACTCGTCCAATTCTATCATAAGAAGGCTAACATGGAGAATAAGCTGAAG
AAGTTGAAATAA

Upstream 100 bases:

>100_bases
AGGAGAGAGTAAAAATAAGTAATTTTTACGAAAATATTGCCCTAGGGATCTCCGATAATAAACTAGGCACGTTGAGCAAA
AAGGGTCCAGAGATTTAAGA

Downstream 100 bases:

>100_bases
CTTCTTGCCATCTGAATTCTCCTGACTAATGTTAGAGGCCAAAGAAATATGAGTGATAAGATACTAGTCGAAGAAAAAGG
AAACACGATCCGCGTTCGTT

Product: putative cAMP-binding protein

Products: NA

Alternate protein names: Crp/Fnr Family Transcriptional Regulator; Transcriptional Regulator; Crp/FNR Family Transcriptional Regulator; Crp Family Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Transcriptional Regulatory Protein; Catabolite Gene Activator; Transcription Regulator; Transcriptional Regulator Crp/Fnr Family Protein; Cyclic AMP Receptor Protein; Histidine Kinase; Stage II Sporulation E Family Protein; CRP Family Transcriptional Regulator; Transcriptional Regulator Crp; Transcriptional Regulator MrpC; CAMP-Dependent Protein Kinase

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MSFFQMVTFPANSYIIVEGKKDANNFYIIREGKVRVTRETAVVGEDPNQVLGPGDFFGVVAAMSQHPQIESATSLTNVSL
ISVSYDQFGTLIQKSTAVAMNIIRFFSMKLRQFDTTITRLSFRNAVEEDPNELFKIGEYYFQQQNTSHATFAYQSYLKHL
PNGQFVPQAKLRLQTMNQAFQSAPIDYTKFNRNYKDSEMIFCEHEPGKELFILQSGKVKISKIVNQNEVMLAVLQAGDIF
GEMAILDNKPRSASAVAAGDVELLAINKANFEGMVKAQPQLATRLITLLSERIWIDYKQLANLLLKDPQGRIVDTLMTLA
EKNRIKVAPKQAYNFEIGTKDLLKMVGLTDPKDELIISDIMKNNKFIRMDMGKIVCSDMAELEKLVQFYHKKANMENKLK
KLK

Sequences:

>Translated_403_residues
MSFFQMVTFPANSYIIVEGKKDANNFYIIREGKVRVTRETAVVGEDPNQVLGPGDFFGVVAAMSQHPQIESATSLTNVSL
ISVSYDQFGTLIQKSTAVAMNIIRFFSMKLRQFDTTITRLSFRNAVEEDPNELFKIGEYYFQQQNTSHATFAYQSYLKHL
PNGQFVPQAKLRLQTMNQAFQSAPIDYTKFNRNYKDSEMIFCEHEPGKELFILQSGKVKISKIVNQNEVMLAVLQAGDIF
GEMAILDNKPRSASAVAAGDVELLAINKANFEGMVKAQPQLATRLITLLSERIWIDYKQLANLLLKDPQGRIVDTLMTLA
EKNRIKVAPKQAYNFEIGTKDLLKMVGLTDPKDELIISDIMKNNKFIRMDMGKIVCSDMAELEKLVQFYHKKANMENKLK
KLK
>Mature_402_residues
SFFQMVTFPANSYIIVEGKKDANNFYIIREGKVRVTRETAVVGEDPNQVLGPGDFFGVVAAMSQHPQIESATSLTNVSLI
SVSYDQFGTLIQKSTAVAMNIIRFFSMKLRQFDTTITRLSFRNAVEEDPNELFKIGEYYFQQQNTSHATFAYQSYLKHLP
NGQFVPQAKLRLQTMNQAFQSAPIDYTKFNRNYKDSEMIFCEHEPGKELFILQSGKVKISKIVNQNEVMLAVLQAGDIFG
EMAILDNKPRSASAVAAGDVELLAINKANFEGMVKAQPQLATRLITLLSERIWIDYKQLANLLLKDPQGRIVDTLMTLAE
KNRIKVAPKQAYNFEIGTKDLLKMVGLTDPKDELIISDIMKNNKFIRMDMGKIVCSDMAELEKLVQFYHKKANMENKLKK
LK

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 45734; Mature: 45602

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS00889 CNMP_BINDING_2 ; PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFFQMVTFPANSYIIVEGKKDANNFYIIREGKVRVTRETAVVGEDPNQVLGPGDFFGVV
CCCEEEEEECCCCEEEEECCCCCCCEEEEECCCEEEEEEEEEECCCCCCCCCCCHHHHHH
AAMSQHPQIESATSLTNVSLISVSYDQFGTLIQKSTAVAMNIIRFFSMKLRQFDTTITRL
HHHHCCCCCCCHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFRNAVEEDPNELFKIGEYYFQQQNTSHATFAYQSYLKHLPNGQFVPQAKLRLQTMNQAF
HHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
QSAPIDYTKFNRNYKDSEMIFCEHEPGKELFILQSGKVKISKIVNQNEVMLAVLQAGDIF
HHCCCCHHHCCCCCCCCCEEEEECCCCCEEEEEECCCEEEEHHCCCCCEEEEEEHHCCHH
GEMAILDNKPRSASAVAAGDVELLAINKANFEGMVKAQPQLATRLITLLSERIWIDYKQL
EEEEEECCCCCCCCEEEECCEEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHEEEHHHH
ANLLLKDPQGRIVDTLMTLAEKNRIKVAPKQAYNFEIGTKDLLKMVGLTDPKDELIISDI
HHHHHCCCCCHHHHHHHHHHHCCCEEECCCCCCEECCCHHHHHHHHCCCCCHHHHHHHHH
MKNNKFIRMDMGKIVCSDMAELEKLVQFYHKKANMENKLKKLK
HHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC
>Mature Secondary Structure 
SFFQMVTFPANSYIIVEGKKDANNFYIIREGKVRVTRETAVVGEDPNQVLGPGDFFGVV
CCEEEEEECCCCEEEEECCCCCCCEEEEECCCEEEEEEEEEECCCCCCCCCCCHHHHHH
AAMSQHPQIESATSLTNVSLISVSYDQFGTLIQKSTAVAMNIIRFFSMKLRQFDTTITRL
HHHHCCCCCCCHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFRNAVEEDPNELFKIGEYYFQQQNTSHATFAYQSYLKHLPNGQFVPQAKLRLQTMNQAF
HHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
QSAPIDYTKFNRNYKDSEMIFCEHEPGKELFILQSGKVKISKIVNQNEVMLAVLQAGDIF
HHCCCCHHHCCCCCCCCCEEEEECCCCCEEEEEECCCEEEEHHCCCCCEEEEEEHHCCHH
GEMAILDNKPRSASAVAAGDVELLAINKANFEGMVKAQPQLATRLITLLSERIWIDYKQL
EEEEEECCCCCCCCEEEECCEEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHEEEHHHH
ANLLLKDPQGRIVDTLMTLAEKNRIKVAPKQAYNFEIGTKDLLKMVGLTDPKDELIISDI
HHHHHCCCCCHHHHHHHHHHHCCCEEECCCCCCEECCCHHHHHHHHCCCCCHHHHHHHHH
MKNNKFIRMDMGKIVCSDMAELEKLVQFYHKKANMENKLKKLK
HHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA