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The map label for this gene is aspC [H]

Identifier: 182680498

GI number: 182680498

Start: 4078696

End: 4079919

Strand: Reverse

Name: aspC [H]

Synonym: Bind_3600

Alternate gene names: 182680498

Gene position: 4079919-4078696 (Counterclockwise)

Preceding gene: 182680499

Following gene: 182680496

Centisome position: 97.84

GC content: 61.11

Gene sequence:

>1224_bases
TTGTCGTCGCCTTTCGCTCATGTCCAGCAATTGCCCCGCGATCCCGTCCTCGGCATTACCGAGGCTTTTGTGGCGGACTC
GTCGCCGCGAAAGGTCAATCTCGGAGTCGGTGTCTATCTCGACGAGAACGGTCACGTTCCGCTTCTCGATTGCGTGCAGC
AAGCCGAGGAAGAATTGCTGCGCCGCAAGGGACCGCACAGCTATGTGCCAATCGACGGAATCGCGGCTTTCGATAATGCC
GTCGCCAGCTTGATCTTCAGCGGAGAGCGTCCCTCGCTCGACGAGCGGCTGGTCACCGTCCAGGCGCTCGGCGGCACTGG
CGCGCTCAAGCTCGGTGCCGATTTTCTGCGCACCACCAATCCCTCCGCGCGCATCTGGATCAGCGATCCAAGCTGGGAAA
ATCATCGCGCTCTCTTCTCCGCCGCCGGCTTCGAGGTCGAAACCTATCCTTATTATCGCGCCGATGGCGGCCTTGATTTC
GCTGGCCTGATTCAGACCCTGTCATCTTTGCCGAGCGGCGACATCCTGCTTCTGCACGCCTGCTGCCATAATCCAACCGG
GCTCGATCTCGAGCCGTACCAATGGGCGGAGATTCAAGCCCTTGCCGCTGAGCGCGGCGTCATTCCCTTCCTCGATGCGG
CCTATCTCGGCTTTGCCGACGGCCTCGACGCAGATCGCGTGGCGATCGATACATTCGCGCAAGCTGGCCTGCCGTTTCTG
GTCTCCTTTTCCTTCTCGAAATCCTTGTCGCTCTATGGCGAACGCGTCGGTGCCCTTGCCGTCGTGACCGGCGGCGCCGC
CGAGCGCGGGCCAGTTCTCAGCCAGATCAAGCGGATCGCGCGCACCACTTATTCGAGCCCGCCAAGCCATGGCGGCGCTA
CCGTTGCCACGATCCTGAATGAGCCGGGCCTTACTGCTCTCTGGCACGATGAATTGGCCCTGATGCGCGATCGCATTAAA
GCCATGCGCGAGGGACTGGCGGAGCGTCTGCGCGTCCAGGTCCCTGATCGCGATTTCAGCTTCATCACGCGCCAGCGCGG
CATGTTTTCTTATTCGGGCCTGTCGAAGGAAGCGGTCGAGATGTTGCGCAGCCGTTTCTCGATCTATGCGCTGGACAGCG
GTCGCATCTGCGTTGCCGCTCTCAATAAGGCCAATCTCGATATTGTGGCGGAAGCCATTGCCACCGTTCTGCGCGAAAGC
GGAGAACAGAGCCTGGTAGCCTGA

Upstream 100 bases:

>100_bases
ATGAACCTGTTGCCTTCGGCATTCGCCAATGCCGGAGTTAAACCCATGGATAATTCGGCGTTCTTGATAGGCAGGGACGC
AAAACCCGGGAATTGAATTC

Downstream 100 bases:

>100_bases
GAAAATAGGCCCGAGGTGCGGGAAATAAATTCTGCACCCGGGCACAAAATGGCATAAAAAACGCATGTGCTAAGCTAGGA
TAGAGCTTATCCAGCTTGGC

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MSSPFAHVQQLPRDPVLGITEAFVADSSPRKVNLGVGVYLDENGHVPLLDCVQQAEEELLRRKGPHSYVPIDGIAAFDNA
VASLIFSGERPSLDERLVTVQALGGTGALKLGADFLRTTNPSARIWISDPSWENHRALFSAAGFEVETYPYYRADGGLDF
AGLIQTLSSLPSGDILLLHACCHNPTGLDLEPYQWAEIQALAAERGVIPFLDAAYLGFADGLDADRVAIDTFAQAGLPFL
VSFSFSKSLSLYGERVGALAVVTGGAAERGPVLSQIKRIARTTYSSPPSHGGATVATILNEPGLTALWHDELALMRDRIK
AMREGLAERLRVQVPDRDFSFITRQRGMFSYSGLSKEAVEMLRSRFSIYALDSGRICVAALNKANLDIVAEAIATVLRES
GEQSLVA

Sequences:

>Translated_407_residues
MSSPFAHVQQLPRDPVLGITEAFVADSSPRKVNLGVGVYLDENGHVPLLDCVQQAEEELLRRKGPHSYVPIDGIAAFDNA
VASLIFSGERPSLDERLVTVQALGGTGALKLGADFLRTTNPSARIWISDPSWENHRALFSAAGFEVETYPYYRADGGLDF
AGLIQTLSSLPSGDILLLHACCHNPTGLDLEPYQWAEIQALAAERGVIPFLDAAYLGFADGLDADRVAIDTFAQAGLPFL
VSFSFSKSLSLYGERVGALAVVTGGAAERGPVLSQIKRIARTTYSSPPSHGGATVATILNEPGLTALWHDELALMRDRIK
AMREGLAERLRVQVPDRDFSFITRQRGMFSYSGLSKEAVEMLRSRFSIYALDSGRICVAALNKANLDIVAEAIATVLRES
GEQSLVA
>Mature_406_residues
SSPFAHVQQLPRDPVLGITEAFVADSSPRKVNLGVGVYLDENGHVPLLDCVQQAEEELLRRKGPHSYVPIDGIAAFDNAV
ASLIFSGERPSLDERLVTVQALGGTGALKLGADFLRTTNPSARIWISDPSWENHRALFSAAGFEVETYPYYRADGGLDFA
GLIQTLSSLPSGDILLLHACCHNPTGLDLEPYQWAEIQALAAERGVIPFLDAAYLGFADGLDADRVAIDTFAQAGLPFLV
SFSFSKSLSLYGERVGALAVVTGGAAERGPVLSQIKRIARTTYSSPPSHGGATVATILNEPGLTALWHDELALMRDRIKA
MREGLAERLRVQVPDRDFSFITRQRGMFSYSGLSKEAVEMLRSRFSIYALDSGRICVAALNKANLDIVAEAIATVLRESG
EQSLVA

Specific function: Biosynthesis of Phe, Tyr, Asp and Leu. [C]

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=398, Percent_Identity=41.2060301507538, Blast_Score=303, Evalue=2e-82,
Organism=Homo sapiens, GI4504067, Length=401, Percent_Identity=42.643391521197, Blast_Score=299, Evalue=4e-81,
Organism=Homo sapiens, GI117414139, Length=396, Percent_Identity=28.5353535353535, Blast_Score=159, Evalue=4e-39,
Organism=Escherichia coli, GI1790488, Length=398, Percent_Identity=47.7386934673367, Blast_Score=372, Evalue=1e-104,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=44.1919191919192, Blast_Score=350, Evalue=1e-97,
Organism=Caenorhabditis elegans, GI71981858, Length=397, Percent_Identity=38.0352644836272, Blast_Score=298, Evalue=4e-81,
Organism=Caenorhabditis elegans, GI25147133, Length=401, Percent_Identity=38.9027431421446, Blast_Score=292, Evalue=2e-79,
Organism=Caenorhabditis elegans, GI17569539, Length=392, Percent_Identity=34.6938775510204, Blast_Score=241, Evalue=5e-64,
Organism=Caenorhabditis elegans, GI17569537, Length=385, Percent_Identity=29.3506493506493, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI25147136, Length=211, Percent_Identity=37.914691943128, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17550384, Length=269, Percent_Identity=32.3420074349442, Blast_Score=142, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6323055, Length=406, Percent_Identity=35.4679802955665, Blast_Score=263, Evalue=3e-71,
Organism=Saccharomyces cerevisiae, GI6322743, Length=434, Percent_Identity=32.9493087557604, Blast_Score=229, Evalue=5e-61,
Organism=Drosophila melanogaster, GI24580972, Length=402, Percent_Identity=40.7960199004975, Blast_Score=298, Evalue=3e-81,
Organism=Drosophila melanogaster, GI24580970, Length=401, Percent_Identity=40.8977556109726, Blast_Score=298, Evalue=5e-81,
Organism=Drosophila melanogaster, GI19920542, Length=391, Percent_Identity=40.920716112532, Blast_Score=292, Evalue=3e-79,
Organism=Drosophila melanogaster, GI24654046, Length=407, Percent_Identity=38.0835380835381, Blast_Score=282, Evalue=3e-76,
Organism=Drosophila melanogaster, GI19922362, Length=407, Percent_Identity=38.0835380835381, Blast_Score=282, Evalue=3e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43963; Mature: 43832

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPFAHVQQLPRDPVLGITEAFVADSSPRKVNLGVGVYLDENGHVPLLDCVQQAEEELL
CCCCHHHHHHCCCCCCCCHHHHHHCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHH
RRKGPHSYVPIDGIAAFDNAVASLIFSGERPSLDERLVTVQALGGTGALKLGADFLRTTN
HHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHEEEEEECCCCCCHHHCHHHHHCCC
PSARIWISDPSWENHRALFSAAGFEVETYPYYRADGGLDFAGLIQTLSSLPSGDILLLHA
CCCEEEEECCCCCCCHHHHHHCCCEEECCCEEECCCCCCHHHHHHHHHHCCCCCEEEEEE
CCHNPTGLDLEPYQWAEIQALAAERGVIPFLDAAYLGFADGLDADRVAIDTFAQAGLPFL
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEE
VSFSFSKSLSLYGERVGALAVVTGGAAERGPVLSQIKRIARTTYSSPPSHGGATVATILN
EEECHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEC
EPGLTALWHDELALMRDRIKAMREGLAERLRVQVPDRDFSFITRQRGMFSYSGLSKEAVE
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHCCCCEECCCCHHHHH
MLRSRFSIYALDSGRICVAALNKANLDIVAEAIATVLRESGEQSLVA
HHHHCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SSPFAHVQQLPRDPVLGITEAFVADSSPRKVNLGVGVYLDENGHVPLLDCVQQAEEELL
CCCHHHHHHCCCCCCCCHHHHHHCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHH
RRKGPHSYVPIDGIAAFDNAVASLIFSGERPSLDERLVTVQALGGTGALKLGADFLRTTN
HHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHEEEEEECCCCCCHHHCHHHHHCCC
PSARIWISDPSWENHRALFSAAGFEVETYPYYRADGGLDFAGLIQTLSSLPSGDILLLHA
CCCEEEEECCCCCCCHHHHHHCCCEEECCCEEECCCCCCHHHHHHHHHHCCCCCEEEEEE
CCHNPTGLDLEPYQWAEIQALAAERGVIPFLDAAYLGFADGLDADRVAIDTFAQAGLPFL
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEE
VSFSFSKSLSLYGERVGALAVVTGGAAERGPVLSQIKRIARTTYSSPPSHGGATVATILN
EEECHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEC
EPGLTALWHDELALMRDRIKAMREGLAERLRVQVPDRDFSFITRQRGMFSYSGLSKEAVE
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHCCCCEECCCCHHHHH
MLRSRFSIYALDSGRICVAALNKANLDIVAEAIATVLRESGEQSLVA
HHHHCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043; 8808952 [H]