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The map label for this gene is plsC [C]

Identifier: 182680462

GI number: 182680462

Start: 4042969

End: 4043763

Strand: Reverse

Name: plsC [C]

Synonym: Bind_3562

Alternate gene names: 182680462

Gene position: 4043763-4042969 (Counterclockwise)

Preceding gene: 182680463

Following gene: 182680461

Centisome position: 96.97

GC content: 57.74

Gene sequence:

>795_bases
ATGATTCTTGTTCGGTCAGTCATCTTCAATATCATCTTTTATCTGGCTCTCGTCGCGCTTTCCCTGACCGGCCTGCCCTG
CCTTCTTCAGGATCGTTTAGCGGCCCAGAATCTTGGCCGGCGTTGGGGACGCGTTTCCCGATGGCTGCTCGAAAAGATCT
GCCGAACAAAAGTGGAATTCCGCGGTCTCGACCATATTCCGCAAGGCGCCTGCATTATCGCCAGCAAGCATCAATCGCTG
CTCGAGACCATGATGCTGCCGCTCCACTCGAAGGATTTTAGTTATATTCTCAAGCGCGAATTGATGTTCCTGCCATTTTT
CGGCTGGTATTTGCGCAAGGCTGGCCAGATTGGCATCAATCGAGCGAAGGGAAGCGCCGCGCTCACCGATCTTACCCGTC
AGGCCTCAAAGGTTCTCGCGGAGGGCCGCCAGATCTTCATCTTTCCCGAGGGCACGCGGCGGCCGCCCGGCGCAGCGCCG
AACTATAAGGCCGGCGTCGCTTTTCTCTATGCCGCGAGTAATGTTCCCTGCGTTCCCGTCGCGGTGAATACAGGGCTTTT
CTGGCCTCGCCGCCGCTTTCTGCGTCGTCCGGGTACGGTCGTCATCGAATATCTCGAGCCAATAGAGCCGGGTCTCGAAA
AAAGGGCCTTCATGCAGCTTCTTGAAACCCGGATCGAGACCGCGACCAATCGGCTGATGGAAGAAGCCATGCGGAACGAC
CCCACCGTGCGGCAGGGGCTCGTCTCGAATGCGCCGGATGTGCCGCAAGAACCTGTGTCCAAGCTCGCTGGTTGA

Upstream 100 bases:

>100_bases
TCGCGCTTCAATGAGGGTGGATACTAGCTGCCGCGTTGATGCTCAAGCATCAAAGTTGTAAAGGGAAAAAACCCATGCAT
TGGGCGAGGGTAGCGATTTC

Downstream 100 bases:

>100_bases
CAGAACGAATCATTTGTTCTAGTTATGTTCTCGTTCCTTGAACGGGAGGCGGCCGCGATGCGGGTGGTTCACCCTTTATC
TCTTTCCATCCTTAGAGGGC

Product: phospholipid/glycerol acyltransferase

Products: CoA; 1,2-diacyl-sn-glycerol 3-phosphate

Alternate protein names: 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase; Acyltransferase; 1-Acylglycerol-3-Phosphate O-Acyltransferase; Acyltransferase Family Protein; Acyltransferase Domain Protein; 1-Acyl-SN-Glycerol-3-Phosphate Acyltransferase; 2-Acylglycerophosphoethanolamine Acyltransferase; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferases; N-Acylhomoserine Lactone Synthase; HdtS Protein; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Protein; 1-Acyl-Sn-Glycerol-3-Phosphateacyltransferase-Like Protein; Acyltransferase Domain-Containing Protein; Scaffold Protein; [Acyl-]Glycerolphosphate Acyltransferase; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Alpha; Acetyltransferase; Phospholipid Biosynthesis-Related Acyltransferase; Protoheme IX Farnesyltransferase; Phospholipid And Glycerol Acyltransferase; 1-Acyl-Sn-Glycerol-3-Phosphate Acetyltransferase; Acylhomoserine Lactone Synthase HdtS; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase PlsC; Acetyltransferase Protein; Cytidylate Kinase; Acyltransferase Family; LPA Acyltransferase Protein

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MILVRSVIFNIIFYLALVALSLTGLPCLLQDRLAAQNLGRRWGRVSRWLLEKICRTKVEFRGLDHIPQGACIIASKHQSL
LETMMLPLHSKDFSYILKRELMFLPFFGWYLRKAGQIGINRAKGSAALTDLTRQASKVLAEGRQIFIFPEGTRRPPGAAP
NYKAGVAFLYAASNVPCVPVAVNTGLFWPRRRFLRRPGTVVIEYLEPIEPGLEKRAFMQLLETRIETATNRLMEEAMRND
PTVRQGLVSNAPDVPQEPVSKLAG

Sequences:

>Translated_264_residues
MILVRSVIFNIIFYLALVALSLTGLPCLLQDRLAAQNLGRRWGRVSRWLLEKICRTKVEFRGLDHIPQGACIIASKHQSL
LETMMLPLHSKDFSYILKRELMFLPFFGWYLRKAGQIGINRAKGSAALTDLTRQASKVLAEGRQIFIFPEGTRRPPGAAP
NYKAGVAFLYAASNVPCVPVAVNTGLFWPRRRFLRRPGTVVIEYLEPIEPGLEKRAFMQLLETRIETATNRLMEEAMRND
PTVRQGLVSNAPDVPQEPVSKLAG
>Mature_264_residues
MILVRSVIFNIIFYLALVALSLTGLPCLLQDRLAAQNLGRRWGRVSRWLLEKICRTKVEFRGLDHIPQGACIIASKHQSL
LETMMLPLHSKDFSYILKRELMFLPFFGWYLRKAGQIGINRAKGSAALTDLTRQASKVLAEGRQIFIFPEGTRRPPGAAP
NYKAGVAFLYAASNVPCVPVAVNTGLFWPRRRFLRRPGTVVIEYLEPIEPGLEKRAFMQLLETRIETATNRLMEEAMRND
PTVRQGLVSNAPDVPQEPVSKLAG

Specific function: Converts Lysophosphatidic Acid (Lpa) Into Phosphatidic Acid By Incorporating An Acyl Moiety At The 2 Position. This Enzyme Can Utilize Either Acyl-CoA Or Acyl-Acyl Carrier Protein As The Fatty Acyl Donor. [C]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6041665, Length=140, Percent_Identity=32.8571428571429, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320151, Length=219, Percent_Identity=26.4840182648402, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24641614, Length=250, Percent_Identity=27.6, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24641612, Length=250, Percent_Identity=27.6, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281364648, Length=202, Percent_Identity=25.2475247524752, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24582856, Length=202, Percent_Identity=25.2475247524752, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24582854, Length=202, Percent_Identity=25.2475247524752, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.51

Molecular weight: Translated: 29730; Mature: 29730

Theoretical pI: Translated: 10.70; Mature: 10.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVRSVIFNIIFYLALVALSLTGLPCLLQDRLAAQNLGRRWGRVSRWLLEKICRTKVEF
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGLDHIPQGACIIASKHQSLLETMMLPLHSKDFSYILKRELMFLPFFGWYLRKAGQIGIN
CCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RAKGSAALTDLTRQASKVLAEGRQIFIFPEGTRRPPGAAPNYKAGVAFLYAASNVPCVPV
CCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCEEEE
AVNTGLFWPRRRFLRRPGTVVIEYLEPIEPGLEKRAFMQLLETRIETATNRLMEEAMRND
EECCCCCHHHHHHHHCCCCEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PTVRQGLVSNAPDVPQEPVSKLAG
CHHHHHHHCCCCCCCHHHHHHHCC
>Mature Secondary Structure
MILVRSVIFNIIFYLALVALSLTGLPCLLQDRLAAQNLGRRWGRVSRWLLEKICRTKVEF
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGLDHIPQGACIIASKHQSLLETMMLPLHSKDFSYILKRELMFLPFFGWYLRKAGQIGIN
CCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RAKGSAALTDLTRQASKVLAEGRQIFIFPEGTRRPPGAAPNYKAGVAFLYAASNVPCVPV
CCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCEEEE
AVNTGLFWPRRRFLRRPGTVVIEYLEPIEPGLEKRAFMQLLETRIETATNRLMEEAMRND
EECCCCCHHHHHHHHCCCCEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PTVRQGLVSNAPDVPQEPVSKLAG
CHHHHHHHCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; 1-acyl-sn-glycerol 3-phosphate

Specific reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA