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The map label for this gene is cobK [H]

Identifier: 182680412

GI number: 182680412

Start: 3991032

End: 3991799

Strand: Reverse

Name: cobK [H]

Synonym: Bind_3512

Alternate gene names: 182680412

Gene position: 3991799-3991032 (Counterclockwise)

Preceding gene: 182680416

Following gene: 182680405

Centisome position: 95.72

GC content: 63.28

Gene sequence:

>768_bases
ATGAAGCAAATCCTTCTCCTTGGTGGCACCAGCGAGGCCAGCGCCTTGGCCAAAATGCTCGCGAGGCGGCCGGATCTTGC
CTGCCTGCTCTCCTTGGCCGGGCGGACCAGCGCGCCGGTGGCGCCGCCCATTTCCTTTCGCATCGGGGGCTTCGGTGGCA
TTGCGGGGCTTGTGGCTTTTCTGCGTGACCACAAGATCGACGTGCTGGTCGATGCGACGCATCCATTCGCGGCGATCATG
TCCGACCATGCGCGTGTGGCGGCGCGGGAAGCAGGGGTCAAGCTCATTACCTTGACCCGCGCGCCCTGGCGGGAACAGGA
GGGCGATCACTGGATTTCCGTCCCGGATATGAAGGCCGCCACGCAGGTTTTGGGACCCATTCCTCGCCGCGTCTTCCTCA
CCATCGGGCGCTTGCAGGTCGAGGCTTTTGTCATGGCGCCGCAGCATTTCTATTTGATCCGCACCATTGAACCGGTGGAG
GATCTGCCCCTGCCCGATTATCATGTCATCCAGGATCGTGGGCCCTTCGACGCCGAACGCGAGGCCGCCTTGCTCGTAGC
GGAACGGATTGATTGTCTCGTCACCAAGAACAGCGGCGGGGCGGCGACCTATGGCAAGATTCTCGCGGCGCGCCGCCTCG
GTCTGCCGGTGATCATGGTCGAAAGGCCGGAGACGGAGTCCTCGGCGGCCATGGTTGTGCATGCACCGGCCGATGTTCTG
GATCTGATCGATGCTCATGAGGTGACACCCATGCCGCGCGGCGTATAG

Upstream 100 bases:

>100_bases
GGTGAGAGGCCGGCGCGGCCGTCCTCGCCAATGCCGATCAGCGACAGCCAAGGGCGGGGCTTTTCACTCATGACGGCCAA
AGCGGAAAAAACGGGGCGCG

Downstream 100 bases:

>100_bases
ACGAAAGGTTGTGTCTGCGTGCGCGCGATCAGGCGTGTCGTGCTGGAGCCGATGAGAACGAGTGTGCTCATATCGGCGCA
TCCGGGCTCGGCTTCAGCCA

Product: precorrin-6x reductase

Products: NA

Alternate protein names: Precorrin-6X reductase [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MKQILLLGGTSEASALAKMLARRPDLACLLSLAGRTSAPVAPPISFRIGGFGGIAGLVAFLRDHKIDVLVDATHPFAAIM
SDHARVAAREAGVKLITLTRAPWREQEGDHWISVPDMKAATQVLGPIPRRVFLTIGRLQVEAFVMAPQHFYLIRTIEPVE
DLPLPDYHVIQDRGPFDAEREAALLVAERIDCLVTKNSGGAATYGKILAARRLGLPVIMVERPETESSAAMVVHAPADVL
DLIDAHEVTPMPRGV

Sequences:

>Translated_255_residues
MKQILLLGGTSEASALAKMLARRPDLACLLSLAGRTSAPVAPPISFRIGGFGGIAGLVAFLRDHKIDVLVDATHPFAAIM
SDHARVAAREAGVKLITLTRAPWREQEGDHWISVPDMKAATQVLGPIPRRVFLTIGRLQVEAFVMAPQHFYLIRTIEPVE
DLPLPDYHVIQDRGPFDAEREAALLVAERIDCLVTKNSGGAATYGKILAARRLGLPVIMVERPETESSAAMVVHAPADVL
DLIDAHEVTPMPRGV
>Mature_255_residues
MKQILLLGGTSEASALAKMLARRPDLACLLSLAGRTSAPVAPPISFRIGGFGGIAGLVAFLRDHKIDVLVDATHPFAAIM
SDHARVAAREAGVKLITLTRAPWREQEGDHWISVPDMKAATQVLGPIPRRVFLTIGRLQVEAFVMAPQHFYLIRTIEPVE
DLPLPDYHVIQDRGPFDAEREAALLVAERIDCLVTKNSGGAATYGKILAARRLGLPVIMVERPETESSAAMVVHAPADVL
DLIDAHEVTPMPRGV

Specific function: Catalyzes the reduction of the macrocycle of precorrin- 6X into precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: =1.3.1.54 [H]

Molecular weight: Translated: 27566; Mature: 27566

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQILLLGGTSEASALAKMLARRPDLACLLSLAGRTSAPVAPPISFRIGGFGGIAGLVAF
CCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHH
LRDHKIDVLVDATHPFAAIMSDHARVAAREAGVKLITLTRAPWREQEGDHWISVPDMKAA
HHCCCEEEEEECCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCEEEECCCHHHH
TQVLGPIPRRVFLTIGRLQVEAFVMAPQHFYLIRTIEPVEDLPLPDYHVIQDRGPFDAER
HHHHCCCCCEEEEEECCEEEEEEEECCCEEEEEEEECCHHHCCCCCEEEECCCCCCCCCH
EAALLVAERIDCLVTKNSGGAATYGKILAARRLGLPVIMVERPETESSAAMVVHAPADVL
HHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEECCHHHH
DLIDAHEVTPMPRGV
HHHHHHCCCCCCCCC
>Mature Secondary Structure
MKQILLLGGTSEASALAKMLARRPDLACLLSLAGRTSAPVAPPISFRIGGFGGIAGLVAF
CCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHH
LRDHKIDVLVDATHPFAAIMSDHARVAAREAGVKLITLTRAPWREQEGDHWISVPDMKAA
HHCCCEEEEEECCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCEEEECCCHHHH
TQVLGPIPRRVFLTIGRLQVEAFVMAPQHFYLIRTIEPVEDLPLPDYHVIQDRGPFDAER
HHHHCCCCCEEEEEECCEEEEEEEECCCEEEEEEEECCHHHCCCCCEEEECCCCCCCCCH
EAALLVAERIDCLVTKNSGGAATYGKILAARRLGLPVIMVERPETESSAAMVVHAPADVL
HHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEECCHHHH
DLIDAHEVTPMPRGV
HHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732193 [H]