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The map label for this gene is qseD [H]

Identifier: 182680356

GI number: 182680356

Start: 3922302

End: 3923219

Strand: Reverse

Name: qseD [H]

Synonym: Bind_3456

Alternate gene names: 182680356

Gene position: 3923219-3922302 (Counterclockwise)

Preceding gene: 182680360

Following gene: 182680355

Centisome position: 94.08

GC content: 61.87

Gene sequence:

>918_bases
ATGGATACCGGGTGGATCGAGGATTTTCTGAAACTCGCGGAGGAGGGTAACTTTTCCCGTGCCGCCGAAGCACGCAATCT
CAGCCAACCCGCCTTTAGCCGTCGCATCAAGGGGCTTGAGGAATGGGTCGGCACCGTCCTGATTGATCGGGACACGCACC
GGATTGCCCTGACTGAAGCCGGGGTCGCGTTTCGGGCTGTCGCGGAGGAAGTCCTGCGCCGCCTCGCGCTTGGGCGAGAT
GAAGCGCGAGAGATTGGAACCACGCAGGCAAACACATTGCGCTTTGCGGCGACCCACGCCCTCTCGACAACCTTCTTTCC
GGATTGGCTGCGCACATTTGAAGATCAGGAGGACGTCGGCACCATTAGTCTGATTGCCGATAATATGCAGGCCTGCGAGC
GTCTCATGCTTGAAGGACGGGTGGATCTGCTGCTTTGCCATCACCATCCTGCCGCATCGCACAAGCTTGACCAAAGCGGG
TTTCGATCGATGGCCCTTGGCGAAGACATCCTTATCCCTGTCTGCGTGCCGGATGCCCAAAACAGGCCCCGTTTCCCCCT
TCCAGGCAGTGACCGGGAGCCGCTGCCGTTTCTCGAATTCGACGAGCGGTCCGGAATGGGGCGTATCCTTGCGGCATCCG
AGGTCATCACCCGCAGCGATGCGTCACTGCGTCCCGTCTTTCGATCCCATCTGGCCAGCGCGTTGTTGAGGATGGCGCGC
GATGGCAAGGGGGTCGCGTGGGCCCCTCTCAGCCTCTGTGCTCCTGACCTCGCGGCGGGCCGGCTCGTGCGCGCCGGCGG
CGAACAATGGAGCGTTCCGCTTGAAATACGGCTTTTCCGCCCTCGTGCGCGTCGAAGCGCCGTCGTCGAAGCTTTCTGGA
ACCGATTGCCCGCTGCCGCTCCTCTCGCAGAGACATGA

Upstream 100 bases:

>100_bases
CGCGAAAGTCCTTTTCTAGCTTATAAAAGCTATCTAACGCGAAGGCCGTGGCACCGGCCAATGCCGGCTTTCGATCAAAT
CATGCGGCGGATGGGATGCG

Downstream 100 bases:

>100_bases
TTGGACTCGAAAGAATGATTATCTCAATGATCTGTCATTATGATCCAGTGAATAGTCTAATTTAATGATAAAATTGGACT
GTAGTCTGGTCCAGACAGGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Quorum-sensing regulator protein D [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MDTGWIEDFLKLAEEGNFSRAAEARNLSQPAFSRRIKGLEEWVGTVLIDRDTHRIALTEAGVAFRAVAEEVLRRLALGRD
EAREIGTTQANTLRFAATHALSTTFFPDWLRTFEDQEDVGTISLIADNMQACERLMLEGRVDLLLCHHHPAASHKLDQSG
FRSMALGEDILIPVCVPDAQNRPRFPLPGSDREPLPFLEFDERSGMGRILAASEVITRSDASLRPVFRSHLASALLRMAR
DGKGVAWAPLSLCAPDLAAGRLVRAGGEQWSVPLEIRLFRPRARRSAVVEAFWNRLPAAAPLAET

Sequences:

>Translated_305_residues
MDTGWIEDFLKLAEEGNFSRAAEARNLSQPAFSRRIKGLEEWVGTVLIDRDTHRIALTEAGVAFRAVAEEVLRRLALGRD
EAREIGTTQANTLRFAATHALSTTFFPDWLRTFEDQEDVGTISLIADNMQACERLMLEGRVDLLLCHHHPAASHKLDQSG
FRSMALGEDILIPVCVPDAQNRPRFPLPGSDREPLPFLEFDERSGMGRILAASEVITRSDASLRPVFRSHLASALLRMAR
DGKGVAWAPLSLCAPDLAAGRLVRAGGEQWSVPLEIRLFRPRARRSAVVEAFWNRLPAAAPLAET
>Mature_305_residues
MDTGWIEDFLKLAEEGNFSRAAEARNLSQPAFSRRIKGLEEWVGTVLIDRDTHRIALTEAGVAFRAVAEEVLRRLALGRD
EAREIGTTQANTLRFAATHALSTTFFPDWLRTFEDQEDVGTISLIADNMQACERLMLEGRVDLLLCHHHPAASHKLDQSG
FRSMALGEDILIPVCVPDAQNRPRFPLPGSDREPLPFLEFDERSGMGRILAASEVITRSDASLRPVFRSHLASALLRMAR
DGKGVAWAPLSLCAPDLAAGRLVRAGGEQWSVPLEIRLFRPRARRSAVVEAFWNRLPAAAPLAET

Specific function: Down-regulates expression of the flagellar regulon, decreasing motility [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790783, Length=297, Percent_Identity=29.96632996633, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI157672245, Length=179, Percent_Identity=28.4916201117318, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786401, Length=271, Percent_Identity=25.0922509225092, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790208, Length=302, Percent_Identity=24.5033112582781, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33841; Mature: 33841

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTGWIEDFLKLAEEGNFSRAAEARNLSQPAFSRRIKGLEEWVGTVLIDRDTHRIALTEA
CCCHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEECCCCEEEEECC
GVAFRAVAEEVLRRLALGRDEAREIGTTQANTLRFAATHALSTTFFPDWLRTFEDQEDVG
CHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCC
TISLIADNMQACERLMLEGRVDLLLCHHHPAASHKLDQSGFRSMALGEDILIPVCVPDAQ
CHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHCCCCHHHHHHHHCCCCCEEEEECCCCC
NRPRFPLPGSDREPLPFLEFDERSGMGRILAASEVITRSDASLRPVFRSHLASALLRMAR
CCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
DGKGVAWAPLSLCAPDLAAGRLVRAGGEQWSVPLEIRLFRPRARRSAVVEAFWNRLPAAA
CCCCEEECHHHHCCCCHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCC
PLAET
CCCCC
>Mature Secondary Structure
MDTGWIEDFLKLAEEGNFSRAAEARNLSQPAFSRRIKGLEEWVGTVLIDRDTHRIALTEA
CCCHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEECCCCEEEEECC
GVAFRAVAEEVLRRLALGRDEAREIGTTQANTLRFAATHALSTTFFPDWLRTFEDQEDVG
CHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCC
TISLIADNMQACERLMLEGRVDLLLCHHHPAASHKLDQSGFRSMALGEDILIPVCVPDAQ
CHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHCCCCHHHHHHHHCCCCCEEEEECCCCC
NRPRFPLPGSDREPLPFLEFDERSGMGRILAASEVITRSDASLRPVFRSHLASALLRMAR
CCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
DGKGVAWAPLSLCAPDLAAGRLVRAGGEQWSVPLEIRLFRPRARRSAVVEAFWNRLPAAA
CCCCEEECHHHHCCCCHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCC
PLAET
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 7876157 [H]