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The map label for this gene is iorA [H]

Identifier: 182680268

GI number: 182680268

Start: 3823512

End: 3823985

Strand: Reverse

Name: iorA [H]

Synonym: Bind_3368

Alternate gene names: 182680268

Gene position: 3823985-3823512 (Counterclockwise)

Preceding gene: 182680269

Following gene: 182680267

Centisome position: 91.7

GC content: 62.03

Gene sequence:

>474_bases
ATGACCAGTTTCACGATCAATGACCGTGCCGTCACGGTGGATGTCGAGGAGGACACGCCGCTCCTCTGGGTTATCCGCGA
AACGATCGGCCTGACCGGCACCAAATTCGGCTGTGGCATTGGCATGTGCGGCGTCTGCACCGTGCATGTTGGGGGGCGCC
CGACGCGCTCCTGCATCACGCCCATCAGTGCGGTCGAGGGTGCGGCGATCACCACCATCGAGGGGATCGCCGCGACCGAT
GCGCATGTGGTGCAAAAGGCCTGGACCGACCTGCAAGTGCCGCAATGCGGCTATTGTCAATCTGGCCAGATCATGCAGGC
CGTTGCCTTGATCAAGGATTTTCCCTCGCCCACGGACGAGGATATCGATGCCGTGATGACCGGCAATCTCTGTCGTTGCA
TGACCTATGTGCGCATTCGCGCGGCCATCAAGCAGGCGGCCGCCGCGCTGCGGGGAGAAGTCACCAATGGCTAG

Upstream 100 bases:

>100_bases
GAAGGTCGCGTCGATCCGCGCGCAAGGCAAGACACAGGAATGAACGCGTGATGGAAGCTCCTTGTCTCGCTTTCGATGCG
ACATCCAATGGAAAACGCTC

Downstream 100 bases:

>100_bases
ACTGGGCTCTATGCAAAATGCCGCGATGATCCAGTCGCGGCGCAGCTTCCTCGTTACTATGGCGGGCGCGAGCCTTGCTT
TCGGCTTTACGCGCGGAGCC

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MTSFTINDRAVTVDVEEDTPLLWVIRETIGLTGTKFGCGIGMCGVCTVHVGGRPTRSCITPISAVEGAAITTIEGIAATD
AHVVQKAWTDLQVPQCGYCQSGQIMQAVALIKDFPSPTDEDIDAVMTGNLCRCMTYVRIRAAIKQAAAALRGEVTNG

Sequences:

>Translated_157_residues
MTSFTINDRAVTVDVEEDTPLLWVIRETIGLTGTKFGCGIGMCGVCTVHVGGRPTRSCITPISAVEGAAITTIEGIAATD
AHVVQKAWTDLQVPQCGYCQSGQIMQAVALIKDFPSPTDEDIDAVMTGNLCRCMTYVRIRAAIKQAAAALRGEVTNG
>Mature_156_residues
TSFTINDRAVTVDVEEDTPLLWVIRETIGLTGTKFGCGIGMCGVCTVHVGGRPTRSCITPISAVEGAAITTIEGIAATDA
HVVQKAWTDLQVPQCGYCQSGQIMQAVALIKDFPSPTDEDIDAVMTGNLCRCMTYVRIRAAIKQAAAALRGEVTNG

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=146, Percent_Identity=36.986301369863, Blast_Score=79, Evalue=1e-15,
Organism=Homo sapiens, GI71773480, Length=93, Percent_Identity=38.7096774193548, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1786480, Length=165, Percent_Identity=38.7878787878788, Blast_Score=111, Evalue=2e-26,
Organism=Escherichia coli, GI1789232, Length=138, Percent_Identity=38.4057971014493, Blast_Score=75, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17540638, Length=151, Percent_Identity=37.7483443708609, Blast_Score=99, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17539860, Length=152, Percent_Identity=33.5526315789474, Blast_Score=98, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI32566215, Length=152, Percent_Identity=34.2105263157895, Blast_Score=96, Evalue=7e-21,
Organism=Drosophila melanogaster, GI17737937, Length=146, Percent_Identity=36.986301369863, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24647193, Length=159, Percent_Identity=34.5911949685535, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24647201, Length=164, Percent_Identity=34.1463414634146, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24647197, Length=154, Percent_Identity=32.4675324675325, Blast_Score=73, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24647195, Length=154, Percent_Identity=32.4675324675325, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24647199, Length=156, Percent_Identity=32.6923076923077, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 16620; Mature: 16489

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSFTINDRAVTVDVEEDTPLLWVIRETIGLTGTKFGCGIGMCGVCTVHVGGRPTRSCIT
CCEEEECCEEEEEEECCCCCEEEEEEHHHCCCCCCCCCCCCCCEEEEEEECCCCCHHHHC
PISAVEGAAITTIEGIAATDAHVVQKAWTDLQVPQCGYCQSGQIMQAVALIKDFPSPTDE
HHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCC
DIDAVMTGNLCRCMTYVRIRAAIKQAAAALRGEVTNG
CHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TSFTINDRAVTVDVEEDTPLLWVIRETIGLTGTKFGCGIGMCGVCTVHVGGRPTRSCIT
CEEEECCEEEEEEECCCCCEEEEEEHHHCCCCCCCCCCCCCCEEEEEEECCCCCHHHHC
PISAVEGAAITTIEGIAATDAHVVQKAWTDLQVPQCGYCQSGQIMQAVALIKDFPSPTDE
HHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCC
DIDAVMTGNLCRCMTYVRIRAAIKQAAAALRGEVTNG
CHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]